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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of protein tyrosine kinase activity
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Accession:GO:0061099 term browser browse the term
Definition:Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity.


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negative regulation of protein tyrosine kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CAV1 caveolin 1 JBrowse link 14 55,458,934 55,494,563 RGD:13508589
G GGNBP2 gametogenetin binding protein 2 JBrowse link 9 36,430,194 36,463,248 RGD:13508589
G HYAL2 hyaluronidase 2 JBrowse link 20 39,029,426 39,034,451 RGD:13508589
G IBTK inhibitor of Bruton tyrosine kinase JBrowse link 12 42,670,082 42,771,179 RGD:13508589
G MVP major vault protein JBrowse link 6 17,879,687 17,903,184 RGD:13508589
G PTPN2 protein tyrosine phosphatase non-receptor type 2 JBrowse link 7 78,160,564 78,252,382 RGD:13508589
G RACK1 receptor for activated C kinase 1 JBrowse link 11 426,734 431,087 RGD:13508589
G SH3BP5 SH3 domain binding protein 5 JBrowse link 23 27,258,502 27,335,175 RGD:13508589
G SH3BP5L SH3 binding domain protein 5 like JBrowse link 16 13,709,586 13,723,908 RGD:13508589
negative regulation of epidermal growth factor-activated receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CBL Cbl proto-oncogene JBrowse link 5 14,600,409 14,676,974 RGD:13508589
G CBLB Cbl proto-oncogene B JBrowse link 33 11,255,453 11,665,755 RGD:13508589
G CBLC Cbl proto-oncogene C JBrowse link 1 110,590,548 110,606,775 RGD:13508589
G ERRFI1 ERBB receptor feedback inhibitor 1 JBrowse link 5 61,621,964 61,636,152 RGD:13508589
G PSEN1 presenilin 1 JBrowse link 8 46,495,551 46,569,532 RGD:13508589
G SOCS4 suppressor of cytokine signaling 4 JBrowse link 8 30,892,663 30,898,896 RGD:13508589
G SOCS5 suppressor of cytokine signaling 5 JBrowse link 10 48,916,446 48,977,183 RGD:13508589
G TSG101 tumor susceptibility 101 JBrowse link 21 40,910,870 40,952,922 RGD:13508589
G VPS25 vacuolar protein sorting 25 homolog JBrowse link 9 20,242,230 20,247,396 RGD:13508589
G ZFYVE28 zinc finger FYVE-type containing 28 JBrowse link 3 61,786,160 61,919,668 RGD:13508589
negative regulation of non-membrane spanning protein tyrosine kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DUSP22 dual specificity phosphatase 22 JBrowse link 35 678,320 733,225 RGD:13508589

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 13312
    metabolic process 8295
      negative regulation of metabolic process 1788
        negative regulation of cellular metabolic process 1613
          negative regulation of cellular protein metabolic process 639
            negative regulation of protein modification process 350
              negative regulation of protein phosphorylation 237
                negative regulation of protein kinase activity 136
                  negative regulation of protein tyrosine kinase activity 20
                    negative regulation of brain-derived neurotrophic factor-activated receptor activity 0
                    negative regulation of epidermal growth factor-activated receptor activity 10
                    negative regulation of non-membrane spanning protein tyrosine kinase activity 1
Path 2
Term Annotations click to browse term
  biological_process 13312
    metabolic process 8295
      organic substance metabolic process 7842
        macromolecule metabolic process 6699
          protein metabolic process 4083
            protein modification process 2773
              cellular protein modification process 2773
                peptidyl-amino acid modification 864
                  peptidyl-tyrosine modification 237
                    peptidyl-tyrosine phosphorylation 234
                      regulation of peptidyl-tyrosine phosphorylation 137
                        negative regulation of peptidyl-tyrosine phosphorylation 31
                          negative regulation of protein tyrosine kinase activity 20
                            negative regulation of brain-derived neurotrophic factor-activated receptor activity 0
                            negative regulation of epidermal growth factor-activated receptor activity 10
                            negative regulation of non-membrane spanning protein tyrosine kinase activity 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.