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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of protein tyrosine kinase activity
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Accession:GO:0061099 term browser browse the term
Definition:Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity.


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negative regulation of protein tyrosine kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CAV1 caveolin 1 JBrowse link 7 116,525,009 116,561,185 RGD:2290271
G CEP43 centrosomal protein 43 JBrowse link 6 166,999,317 167,052,718 RGD:2290271
G GGNBP2 gametogenetin binding protein 2 JBrowse link 17 36,544,913 36,589,848 RGD:2290271
G HYAL2 hyaluronidase 2 JBrowse link 3 50,317,790 50,322,850 RGD:2290271
G IBTK inhibitor of Bruton tyrosine kinase JBrowse link 6 82,169,987 82,247,747 RGD:2290271
G MVP major vault protein JBrowse link 16 29,820,394 29,848,039 RGD:2290271
G PTK6 protein tyrosine kinase 6 JBrowse link 20 63,528,001 63,537,376 RGD:2290271
G PTPN2 protein tyrosine phosphatase non-receptor type 2 JBrowse link 18 12,785,478 12,884,351 RGD:2290271
G PTPRC protein tyrosine phosphatase receptor type C JBrowse link 1 198,638,968 198,757,476 RGD:2290271
G RACK1 receptor for activated C kinase 1 JBrowse link 5 181,236,897 181,243,906 RGD:2290271
G SH3BP5 SH3 domain binding protein 5 JBrowse link 3 15,254,353 15,341,380 RGD:2290271
G SH3BP5L SH3 binding domain protein 5 like JBrowse link 1 248,810,446 248,825,915 RGD:2290271
G SRCIN1 SRC kinase signaling inhibitor 1 JBrowse link 17 38,530,015 38,607,166 RGD:2290271
G THY1 Thy-1 cell surface antigen JBrowse link 11 119,415,476 119,424,985 RGD:2290271
negative regulation of epidermal growth factor-activated receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CBL Cbl proto-oncogene JBrowse link 11 119,206,339 119,308,149 RGD:2290271
G CBLB Cbl proto-oncogene B JBrowse link 3 105,655,461 105,869,552 RGD:2290271
G CBLC Cbl proto-oncogene C JBrowse link 19 44,777,855 44,800,652 RGD:2290271
G CHMP6 charged multivesicular body protein 6 JBrowse link 17 80,991,841 81,000,133 RGD:2290271
G ERRFI1 ERBB receptor feedback inhibitor 1 JBrowse link 1 8,011,725 8,026,309 RGD:2290271
G GPRC5A G protein-coupled receptor class C group 5 member A JBrowse link 12 12,891,562 12,917,937 RGD:2290271
G PSEN1 presenilin 1 JBrowse link 14 73,136,436 73,223,691 RGD:2290271
G SNX6 sorting nexin 6 JBrowse link 14 34,561,093 34,630,148 RGD:2290271
G SOCS4 suppressor of cytokine signaling 4 JBrowse link 14 55,027,131 55,049,489 RGD:2290271
G SOCS5 suppressor of cytokine signaling 5 JBrowse link 2 46,698,960 46,763,129 RGD:2290271
G TSG101 tumor susceptibility 101 JBrowse link 11 18,480,311 18,526,942 RGD:2290271
G VPS25 vacuolar protein sorting 25 homolog JBrowse link 17 42,773,449 42,779,599 RGD:2290271
G ZFYVE28 zinc finger FYVE-type containing 28 JBrowse link 4 2,269,585 2,418,698 RGD:2290271
G ZGPAT zinc finger CCCH-type and G-patch domain containing JBrowse link 20 63,707,442 63,736,142 RGD:2290271
negative regulation of non-membrane spanning protein tyrosine kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DUSP22 dual specificity phosphatase 22 JBrowse link 6 292,057 351,355 RGD:2290271

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17988
    metabolic process 11592
      negative regulation of metabolic process 3130
        negative regulation of cellular metabolic process 2671
          negative regulation of cellular protein metabolic process 1058
            negative regulation of protein modification process 607
              negative regulation of protein phosphorylation 409
                negative regulation of protein kinase activity 231
                  negative regulation of protein tyrosine kinase activity 29
                    negative regulation of brain-derived neurotrophic factor-activated receptor activity 0
                    negative regulation of epidermal growth factor-activated receptor activity 14
                    negative regulation of non-membrane spanning protein tyrosine kinase activity 1
Path 2
Term Annotations click to browse term
  biological_process 17988
    metabolic process 11592
      organic substance metabolic process 11013
        macromolecule metabolic process 9483
          protein metabolic process 5904
            protein modification process 4217
              cellular protein modification process 4217
                peptidyl-amino acid modification 1290
                  peptidyl-tyrosine modification 376
                    peptidyl-tyrosine phosphorylation 373
                      regulation of peptidyl-tyrosine phosphorylation 255
                        negative regulation of peptidyl-tyrosine phosphorylation 51
                          negative regulation of protein tyrosine kinase activity 29
                            negative regulation of brain-derived neurotrophic factor-activated receptor activity 0
                            negative regulation of epidermal growth factor-activated receptor activity 14
                            negative regulation of non-membrane spanning protein tyrosine kinase activity 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.