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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of protein tyrosine kinase activity
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Accession:GO:0061099 term browser browse the term
Definition:Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity.


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negative regulation of protein tyrosine kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cav1 caveolin 1, caveolae protein JBrowse link 6 17,306,335 17,341,328 RGD:2290270
G Ggnbp2 gametogenetin binding protein 2 JBrowse link 11 84,832,361 84,870,837 RGD:2290270
G Gm45915 predicted gene, 45915 JBrowse link 14 25,603,513 25,605,636 RGD:2290270
G Hyal2 hyaluronoglucosaminidase 2 JBrowse link 9 107,567,873 107,572,778 RGD:2290270
G Mvp major vault protein JBrowse link 7 126,986,860 127,014,594 RGD:2290270
G Ptk6 PTK6 protein tyrosine kinase 6 JBrowse link 2 181,195,124 181,202,789 RGD:2290270
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 JBrowse link 18 67,665,501 67,724,632 RGD:2290270
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 1 138,062,859 138,175,756 RGD:2290270
G Sh3bp5 SH3-domain binding protein 5 (BTK-associated) JBrowse link 14 31,372,614 31,436,100 RGD:2290270
G Sh3bp5l SH3 binding domain protein 5 like JBrowse link 11 58,330,707 58,347,728 RGD:2290270
G Srcin1 SRC kinase signaling inhibitor 1 JBrowse link 11 97,509,340 97,575,246 RGD:2290270
G Thy1 thymus cell antigen 1, theta JBrowse link 9 44,043,384 44,048,579 RGD:2290270
negative regulation of brain-derived neurotrophic factor-activated receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fam72a family with sequence similarity 72, member A JBrowse link 1 131,526,598 131,539,035 RGD:2290270
negative regulation of epidermal growth factor-activated receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cbl Casitas B-lineage lymphoma JBrowse link 9 44,142,976 44,234,259 RGD:2290270
G Cblb Casitas B-lineage lymphoma b JBrowse link 16 52,031,230 52,208,047 RGD:2290270
G Cblc Casitas B-lineage lymphoma c JBrowse link 7 19,779,718 19,796,809 RGD:2290270
G Chmp6 charged multivesicular body protein 6 JBrowse link 11 119,913,409 119,919,552 RGD:2290270
G Errfi1 ERBB receptor feedback inhibitor 1 JBrowse link 4 150,853,796 150,868,889 RGD:2290270
G Gprc5a G protein-coupled receptor, family C, group 5, member A JBrowse link 6 135,065,662 135,084,709 RGD:2290270
G Psen1 presenilin 1 JBrowse link 12 83,688,152 83,735,095 RGD:2290270
G Psen2 presenilin 2 JBrowse link 1 180,227,004 180,263,467 RGD:2290270
G Socs4 suppressor of cytokine signaling 4 JBrowse link 14 47,277,143 47,291,591 RGD:2290270
G Socs5 suppressor of cytokine signaling 5 JBrowse link 17 87,107,278 87,137,647 RGD:2290270
G Tsg101 tumor susceptibility gene 101 JBrowse link 7 46,888,949 46,926,320 RGD:2290270
G Vps25 vacuolar protein sorting 25 JBrowse link 11 101,252,326 101,259,551 RGD:2290270
G Zfyve28 zinc finger, FYVE domain containing 28 JBrowse link 5 34,194,893 34,288,368 RGD:2290270
G Zgpat zinc finger, CCCH-type with G patch domain JBrowse link 2 181,364,931 181,380,793 RGD:2290270
negative regulation of non-membrane spanning protein tyrosine kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dusp22 dual specificity phosphatase 22 JBrowse link 13 30,660,059 30,711,232 RGD:2290270

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23017
    metabolic process 10332
      negative regulation of metabolic process 2858
        negative regulation of cellular metabolic process 2446
          negative regulation of cellular protein metabolic process 1004
            negative regulation of protein modification process 568
              negative regulation of protein phosphorylation 411
                negative regulation of protein kinase activity 197
                  negative regulation of protein tyrosine kinase activity 28
                    negative regulation of brain-derived neurotrophic factor-activated receptor activity 1
                    negative regulation of epidermal growth factor-activated receptor activity 14
                    negative regulation of non-membrane spanning protein tyrosine kinase activity 1
Path 2
Term Annotations click to browse term
  biological_process 23017
    metabolic process 10332
      organic substance metabolic process 9795
        macromolecule metabolic process 8329
          protein metabolic process 5165
            protein modification process 3440
              cellular protein modification process 3440
                peptidyl-amino acid modification 1144
                  peptidyl-tyrosine modification 324
                    peptidyl-tyrosine phosphorylation 321
                      regulation of peptidyl-tyrosine phosphorylation 265
                        negative regulation of peptidyl-tyrosine phosphorylation 56
                          negative regulation of protein tyrosine kinase activity 28
                            negative regulation of brain-derived neurotrophic factor-activated receptor activity 1
                            negative regulation of epidermal growth factor-activated receptor activity 14
                            negative regulation of non-membrane spanning protein tyrosine kinase activity 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.