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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of protein tyrosine kinase activity
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Accession:GO:0061099 term browser browse the term
Definition:Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity.


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negative regulation of protein tyrosine kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CAV1 caveolin 1 JBrowse link 18 29,648,120 29,682,451 RGD:14298760
G FGFR1OP FGFR1 oncogene partner JBrowse link 1 2,093,329 2,120,832 RGD:14298760
G GGNBP2 gametogenetin binding protein 2 JBrowse link 12 38,074,033 38,111,719 RGD:14298760
G HYAL2 hyaluronidase 2 JBrowse link 13 32,805,220 32,813,684 RGD:14298760
G IBTK inhibitor of Bruton tyrosine kinase JBrowse link 1 83,973,541 84,070,751 RGD:14298760
G MVP major vault protein JBrowse link 3 18,056,548 18,081,169 RGD:14298760
G PTK6 protein tyrosine kinase 6 JBrowse link 17 62,538,853 62,547,866 RGD:14298760
G PTPN2 protein tyrosine phosphatase non-receptor type 2 JBrowse link 6 96,769,862 96,847,136 RGD:14298760
G PTPRC protein tyrosine phosphatase receptor type C JBrowse link 10 21,482,984 21,601,627 RGD:14298760
G RACK1 receptor for activated C kinase 1 JBrowse link 2 57,280,192 57,284,846 RGD:14298760
G SH3BP5 SH3 domain binding protein 5 JBrowse link 13 2,504,282 2,585,601 RGD:14298760
G SH3BP5L SH3 binding domain protein 5 like JBrowse link 2 52,323,009 52,337,198 RGD:14298760
G SRCIN1 SRC kinase signaling inhibitor 1 JBrowse link 12 23,494,487 23,571,560 RGD:14298760
negative regulation of epidermal growth factor-activated receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CBL Cbl proto-oncogene JBrowse link 9 46,416,937 46,512,855 RGD:14298760
G CBLB Cbl proto-oncogene B JBrowse link 13 153,480,525 153,700,115 RGD:14298760
G CBLC Cbl proto-oncogene C JBrowse link 6 51,274,717 51,292,546 RGD:14298760
G CHMP6 charged multivesicular body protein 6 JBrowse link 12 1,691,821 1,698,347 RGD:14298760
G ERRFI1 ERBB receptor feedback inhibitor 1 JBrowse link 6 68,667,651 68,682,629 RGD:14298760
G PSEN1 presenilin 1 JBrowse link 7 96,478,179 96,567,884 RGD:14298760
G SOCS4 suppressor of cytokine signaling 4 JBrowse link 1 184,379,017 184,398,902 RGD:14298760
G SOCS5 suppressor of cytokine signaling 5 JBrowse link 3 93,777,402 93,925,859 RGD:14298760
G VPS25 vacuolar protein sorting 25 homolog JBrowse link 12 20,082,864 20,088,443 RGD:14298760
G ZFYVE28 zinc finger FYVE-type containing 28 JBrowse link 8 1,225,417 1,312,938 RGD:14298760
negative regulation of non-membrane spanning protein tyrosine kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DUSP22 dual specificity phosphatase 22 JBrowse link 7 43,437 96,270 RGD:14298760

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14320
    metabolic process 8826
      negative regulation of metabolic process 2080
        negative regulation of cellular metabolic process 1869
          negative regulation of cellular protein metabolic process 747
            negative regulation of protein modification process 423
              negative regulation of protein phosphorylation 286
                negative regulation of protein kinase activity 168
                  negative regulation of protein tyrosine kinase activity 24
                    negative regulation of brain-derived neurotrophic factor-activated receptor activity 0
                    negative regulation of epidermal growth factor-activated receptor activity 10
                    negative regulation of non-membrane spanning protein tyrosine kinase activity 1
Path 2
Term Annotations click to browse term
  biological_process 14320
    metabolic process 8826
      organic substance metabolic process 8295
        macromolecule metabolic process 7115
          protein metabolic process 4358
            protein modification process 2969
              cellular protein modification process 2969
                peptidyl-amino acid modification 936
                  peptidyl-tyrosine modification 265
                    peptidyl-tyrosine phosphorylation 263
                      regulation of peptidyl-tyrosine phosphorylation 177
                        negative regulation of peptidyl-tyrosine phosphorylation 41
                          negative regulation of protein tyrosine kinase activity 24
                            negative regulation of brain-derived neurotrophic factor-activated receptor activity 0
                            negative regulation of epidermal growth factor-activated receptor activity 10
                            negative regulation of non-membrane spanning protein tyrosine kinase activity 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.