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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of protein tyrosine kinase activity
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Accession:GO:0061099 term browser browse the term
Definition:Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity.


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negative regulation of protein tyrosine kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ahsg alpha-2-HS-glycoprotein JBrowse link 11 81,711,269 81,717,594 RGD:1600115
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:1624291
RGD:13792537
RGD:1600115
G Fgfr1op Fgfr1 oncogene partner JBrowse link 1 53,122,330 53,152,872 RGD:1600115
G Ggnbp2 gametogenetin binding protein 2 JBrowse link 10 72,156,729 72,188,834 RGD:1624291
RGD:1600115
G Hyal2 hyaluronidase 2 JBrowse link 8 116,324,062 116,328,978 RGD:1600115
RGD:1624291
G Ibtk inhibitor of Bruton tyrosine kinase JBrowse link 8 93,323,454 93,397,044 RGD:1600115
G Mvp major vault protein JBrowse link 1 198,420,813 198,448,612 RGD:1600115
RGD:1624291
G Ptk6 protein tyrosine kinase 6 JBrowse link 3 176,698,305 176,706,896 RGD:1624291
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 JBrowse link 18 63,415,298 63,489,240 RGD:1624291
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 13 55,061,561 55,174,150 RGD:1624291
G Rack1 receptor for activated C kinase 1 JBrowse link 10 34,149,717 34,155,198 RGD:1600115
G Sh3bp5 SH3-domain binding protein 5 JBrowse link 16 7,473,367 7,559,976 RGD:13792537
G Sh3bp5l SH3 binding domain protein 5 like JBrowse link 10 43,768,620 43,785,702 RGD:13792537
G Srcin1 SRC kinase signaling inhibitor 1 JBrowse link 10 85,460,059 85,517,671 RGD:1624291
RGD:1600115
G Thy1 Thy-1 cell surface antigen JBrowse link 8 48,382,121 48,387,271 RGD:12793046
negative regulation of brain-derived neurotrophic factor-activated receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fam72a family with sequence similarity 72, member A JBrowse link 13 48,288,071 48,298,604 RGD:8553945
negative regulation of epidermal growth factor-activated receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cbl Cbl proto-oncogene JBrowse link 8 48,481,256 48,564,775 RGD:13792537
G Cblb Cbl proto-oncogene B JBrowse link 11 51,037,383 51,202,761 RGD:13792537
G Cblc Cbl proto-oncogene C JBrowse link 1 80,699,321 80,716,146 RGD:1624291
RGD:13792537
G Chmp6 charged multivesicular body protein 6 JBrowse link 10 109,073,678 109,079,348 RGD:1624291
G Errfi1 ERBB receptor feedback inhibitor 1 JBrowse link 5 167,951,564 167,966,011 RGD:8553726
RGD:1600115
RGD:1624291
G Gprc5a G protein-coupled receptor, class C, group 5, member A JBrowse link 4 168,832,937 168,851,650 RGD:1624291
G Psen1 presenilin 1 JBrowse link 6 107,169,514 107,221,000 RGD:1624291
G Psen2 presenilin 2 JBrowse link 13 98,513,600 98,539,347 RGD:1624291
G Socs4 suppressor of cytokine signaling 4 JBrowse link 15 24,056,383 24,070,868 RGD:1624291
G Socs5 suppressor of cytokine signaling 5 JBrowse link 6 10,671,311 10,705,610 RGD:1624291
G Tsg101 tumor susceptibility 101 JBrowse link 1 102,941,151 102,971,017 RGD:1624291
G Vps25 vacuolar protein sorting 25 homolog JBrowse link 10 89,174,684 89,180,165 RGD:1624291
G Zfyve28 zinc finger FYVE-type containing 28 JBrowse link 14 81,725,513 81,811,142 RGD:1624291
RGD:13792537
G Zgpat zinc finger CCCH-type and G-patch domain containing JBrowse link 3 176,865,078 176,881,603 RGD:1624291
RGD:1600115
negative regulation of non-membrane spanning protein tyrosine kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dusp22 dual specificity phosphatase 22 JBrowse link 17 34,986,589 35,037,297 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19332
    metabolic process 11554
      negative regulation of metabolic process 3059
        negative regulation of cellular metabolic process 2677
          negative regulation of cellular protein metabolic process 1113
            negative regulation of protein modification process 626
              negative regulation of protein phosphorylation 430
                negative regulation of protein kinase activity 223
                  negative regulation of protein tyrosine kinase activity 31
                    negative regulation of brain-derived neurotrophic factor-activated receptor activity 1
                    negative regulation of epidermal growth factor-activated receptor activity 14
                    negative regulation of non-membrane spanning protein tyrosine kinase activity 1
Path 2
Term Annotations click to browse term
  biological_process 19332
    metabolic process 11554
      organic substance metabolic process 10949
        macromolecule metabolic process 9418
          protein metabolic process 5973
            protein modification process 3851
              cellular protein modification process 3851
                peptidyl-amino acid modification 1272
                  peptidyl-tyrosine modification 390
                    peptidyl-tyrosine phosphorylation 387
                      regulation of peptidyl-tyrosine phosphorylation 276
                        negative regulation of peptidyl-tyrosine phosphorylation 57
                          negative regulation of protein tyrosine kinase activity 31
                            negative regulation of brain-derived neurotrophic factor-activated receptor activity 1
                            negative regulation of epidermal growth factor-activated receptor activity 14
                            negative regulation of non-membrane spanning protein tyrosine kinase activity 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.