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ONTOLOGY REPORT - ANNOTATIONS


Term:mammary gland epithelium development
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Accession:GO:0061180 term browser browse the term
Definition:The process whose specific outcome is the progression of the mammary gland epithelium over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.
Synonyms:exact_synonym: breast epithelium development


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mammary gland epithelium development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2c2 ATPase secretory pathway Ca2+ transporting 2 ISO
IEA
(MGI:MGI:5528587|PMID:23840669)
GO_REF:0000107
RGD
Ensembl
PMID:23840669 GO_REF:0000107, MGI:MGI:5528587 NCBI chr19:52,347,480...52,404,608
Ensembl chr19:52,347,580...52,404,607
JBrowse link
G Jak2 Janus kinase 2 ISO (MGI:MGI:2180453|PMID:12040017) RGD PMID:12040017 MGI:MGI:2180453 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Msx1 msh homeobox 1 ISO MGI:MGI:97169 (MGI:MGI:1355063|PMID:10742104) RGD PMID:10742104 MGI:MGI:1355063 NCBI chr14:77,712,262...77,716,061
Ensembl chr14:77,712,240...77,716,059
JBrowse link
G Msx2 msh homeobox 2 ISO MGI:MGI:97168 (MGI:MGI:1355063|PMID:10742104) RGD PMID:10742104 MGI:MGI:1355063 NCBI chr17:11,683,862...11,689,527
Ensembl chr17:11,683,862...11,689,527
JBrowse link
G Orai1 ORAI calcium release-activated calcium modulator 1 ISO
IEA
(MGI:MGI:5528587|PMID:23840669)
GO_REF:0000107
RGD
Ensembl
PMID:23840669 GO_REF:0000107, MGI:MGI:5528587 NCBI chr12:38,981,903...38,995,570
Ensembl chr12:38,981,927...38,995,570
JBrowse link
G Prlr prolactin receptor ISO (MGI:MGI:2180453|PMID:12040017) RGD PMID:12040017 MGI:MGI:2180453 NCBI chr 2:60,131,410...60,325,686
Ensembl chr 2:60,131,776...60,325,692
JBrowse link
G Stat5a signal transducer and activator of transcription 5A ISO MGI:MGI:103035|MGI:MGI:103036 (MGI:MGI:2180453|PMID:12040017) RGD PMID:12040017 MGI:MGI:2180453 NCBI chr10:88,764,732...88,789,060
Ensembl chr10:88,764,732...88,789,057
JBrowse link
G Wnt2 Wnt family member 2 ISO (PMID:8168088) RGD PMID:8168088 NCBI chr 4:45,286,845...45,332,899
Ensembl chr 4:45,292,437...45,332,420
JBrowse link
G Wnt3 Wnt family member 3 ISO
IEA
(PMID:8168088)
GO_REF:0000107
RGD
Ensembl
PMID:8168088 GO_REF:0000107 NCBI chr10:91,830,709...91,874,907
Ensembl chr10:91,830,654...91,874,793
JBrowse link
G Wnt4 Wnt family member 4 ISO (PMID:8168088) RGD PMID:8168088 NCBI chr 5:155,649,238...155,668,065
Ensembl chr 5:155,649,217...155,672,579
JBrowse link
G Wnt7b Wnt family member 7B ISO (PMID:8168088) RGD PMID:8168088 NCBI chr 7:126,423,418...126,465,724
Ensembl chr 7:126,420,656...126,465,723
JBrowse link
branch elongation involved in mammary gland duct branching term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfb1 transforming growth factor, beta 1 ISO MGI:MGI:1857258 (MGI:MGI:3814777|PMID:18614704) RGD PMID:18614704 MGI:MGI:3814777 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
branching involved in mammary gland duct morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07034833.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr12:53,872...54,885 JBrowse link
G AABR07071701.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 8:126,975,833...126,976,850 JBrowse link
G Btrc beta-transducin repeat containing E3 ubiquitin protein ligase ISO MGI:MGI:3055737 (MGI:MGI:3054694|PMID:15340078) RGD PMID:15340078 MGI:MGI:3054694 NCBI chr 1:265,100,094...265,270,263
Ensembl chr 1:265,157,379...265,269,837
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 ISO MGI:MGI:2384435 (MGI:MGI:3640884|PMID:10804170) RGD PMID:10804170 MGI:MGI:3640884 NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575
JBrowse link
G Csf1 colony stimulating factor 1 ISO MGI:MGI:1856333 (MGI:MGI:3640884|PMID:10804170) RGD PMID:10804170 MGI:MGI:3640884 NCBI chr 2:210,522,370...210,550,546
Ensembl chr 2:210,522,375...210,550,560
JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 ISO
IEA
MGI:MGI:2388024 (MGI:MGI:1932625|PMID:11283268)
GO_REF:0000107
RGD
Ensembl
PMID:11283268 GO_REF:0000107, MGI:MGI:1932625 NCBI chr20:3,553,430...3,574,959
Ensembl chr20:3,552,929...3,575,780
JBrowse link
G Epha2 Eph receptor A2 ISO (MGI:MGI:5284750|PMID:19321667) RGD PMID:19321667 MGI:MGI:5284750 NCBI chr 5:159,845,773...159,874,203
Ensembl chr 5:159,845,774...159,874,206
JBrowse link
G Etv4 ETS variant transcription factor 4 ISO MGI:MGI:2445834 (MGI:MGI:2667785|PMID:12871699), (MGI:MGI:3828920|PMID:18977342) RGD PMID:12871699, PMID:18977342 MGI:MGI:2667785, MGI:MGI:3828920 NCBI chr10:89,685,058...89,700,300
Ensembl chr10:89,685,058...89,700,283
JBrowse link
G Kdm5b lysine demethylase 5B ISO MGI:MGI:4329395 (MGI:MGI:5619178|PMID:24802759) RGD PMID:24802759 MGI:MGI:5619178 NCBI chr13:51,384,371...51,455,392
Ensembl chr13:51,384,389...51,455,357
JBrowse link
G LOC102554748 nidogen-2-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:380,313...427,615
Ensembl chr 7:380,741...381,732
JBrowse link
G Lrp5 LDL receptor related protein 5 ISO
IBA
MGI:MGI:3663738 (MGI:MGI:3692480|PMID:16973609)
PMID:21873635
RGD PMID:16973609, PMID:21873635 MGI:MGI:3692480, RGD:13792537 NCBI chr 1:218,816,833...218,920,147
Ensembl chr 1:218,816,841...218,920,094
JBrowse link
G Lrp6 LDL receptor related protein 6 ISO
IBA
MGI:MGI:2156191 (MGI:MGI:3849913|PMID:19503830)
PMID:21873635
RGD PMID:19503830, PMID:21873635 MGI:MGI:3849913, RGD:13792537 NCBI chr 4:168,194,054...168,323,962
Ensembl chr 4:168,194,927...168,323,751
JBrowse link
G Msx2 msh homeobox 2 ISO
IEA
MGI:MGI:1926381 (MGI:MGI:1355063|PMID:10742104)
GO_REF:0000107
RGD
Ensembl
PMID:10742104 GO_REF:0000107, MGI:MGI:1355063 NCBI chr17:11,683,862...11,689,527
Ensembl chr17:11,683,862...11,689,527
JBrowse link
G Pml PML nuclear body scaffold ISO MGI:MGI:2429949 (MGI:MGI:3839212|PMID:19261859) RGD PMID:19261859 MGI:MGI:3839212 NCBI chr 8:63,002,515...63,034,310
Ensembl chr 8:63,004,870...63,034,226
JBrowse link
G Slc12a2 solute carrier family 12 member 2 ISO MGI:MGI:1935144 (MGI:MGI:2180693|PMID:8864124) RGD PMID:8864124 MGI:MGI:2180693 NCBI chr18:52,917,124...52,985,281
Ensembl chr18:52,917,124...52,985,261
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO MGI:MGI:1857247 (MGI:MGI:3589531|PMID:16007215) RGD PMID:16007215 MGI:MGI:3589531 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Tbx3 T-box transcription factor 3 ISO MGI:MGI:2655214 (MGI:MGI:3608166|PMID:16222716) RGD PMID:16222716 MGI:MGI:3608166 NCBI chr12:42,479,518...42,494,588
Ensembl chr12:42,480,560...42,492,526
JBrowse link
dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Areg amphiregulin ISO MGI:MGI:2176531 (MGI:MGI:3703920|PMID:17369357) RGD PMID:17369357 MGI:MGI:3703920 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
JBrowse link
G Tfap2c transcription factor AP-2 gamma ISO MGI:MGI:3040993 (MGI:MGI:4422106|PMID:20131354) RGD PMID:20131354 MGI:MGI:4422106 NCBI chr 3:170,550,314...170,558,197
Ensembl chr 3:170,550,314...170,558,194
JBrowse link
epithelial cell differentiation involved in mammary gland alveolus development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxb1 forkhead box B1 ISO
ISS
(MGI:MGI:1931655|PMID:11170346)
GO_REF:0000024
RGD
UniProt
PMID:11170346 GO_REF:0000024, MGI:MGI:1931655 NCBI chr 8:75,992,751...75,995,371
Ensembl chr 8:75,992,755...75,995,371
JBrowse link
G Foxf1 forkhead box F1 ISO MGI:MGI:96432 (MGI:MGI:3640953|PMID:16691571) RGD PMID:16691571 MGI:MGI:3640953 NCBI chr19:53,012,306...53,016,100
Ensembl chr19:53,012,332...53,016,086
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha ISO
IEA
MGI:MGI:2386679 (MGI:MGI:2654263|PMID:12620994)
GO_REF:0000107
RGD
Ensembl
PMID:12620994 GO_REF:0000107, MGI:MGI:2654263 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Id2 inhibitor of DNA binding 2 ISO
ISS
(MGI:MGI:2446740|PMID:12456807)
GO_REF:0000024
RGD
UniProt
PMID:12456807 GO_REF:0000024, MGI:MGI:2446740 NCBI chr 6:44,360,077...44,361,908
Ensembl chr 6:44,348,501...44,363,915
JBrowse link
epithelial cell proliferation involved in mammary gland duct elongation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Areg amphiregulin ISO MGI:MGI:2176531 (MGI:MGI:3703920|PMID:17369357) RGD PMID:17369357 MGI:MGI:3703920 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
JBrowse link
G Esr1 estrogen receptor 1 ISO
IEA
MGI:MGI:2150897 (MGI:MGI:3629536|PMID:12021201)
GO_REF:0000107
RGD
Ensembl
PMID:12021201 GO_REF:0000107, MGI:MGI:3629536 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Med1 mediator complex subunit 1 ISO MGI:MGI:3511276 (MGI:MGI:3576991|PMID:15647257) RGD PMID:15647257 MGI:MGI:3576991 NCBI chr10:86,101,560...86,145,271
Ensembl chr10:86,103,600...86,144,880
JBrowse link
G Tfap2c transcription factor AP-2 gamma ISO MGI:MGI:3040993 (MGI:MGI:4422106|PMID:20131354) RGD PMID:20131354 MGI:MGI:4422106 NCBI chr 3:170,550,314...170,558,197
Ensembl chr 3:170,550,314...170,558,194
JBrowse link
G Wnt5a Wnt family member 5A ISO
IEA
(MGI:MGI:3761053|PMID:17898001)
GO_REF:0000107
RGD
Ensembl
PMID:17898001 GO_REF:0000107, MGI:MGI:3761053 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
lateral sprouting involved in mammary gland duct morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor ISO
IEA
MGI:MGI:2687199 (MGI:MGI:2683859|PMID:14676301)
GO_REF:0000107
RGD
Ensembl
PMID:14676301 GO_REF:0000107, MGI:MGI:2683859 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Wnt5a Wnt family member 5A ISO
IEA
(MGI:MGI:3761053|PMID:17898001)
GO_REF:0000107
RGD
Ensembl
PMID:17898001 GO_REF:0000107, MGI:MGI:3761053 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
mammary duct terminal end bud growth term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl11 C-C motif chemokine ligand 11 ISO MGI:MGI:2384435 (MGI:MGI:3640884|PMID:10804170) RGD PMID:10804170 MGI:MGI:3640884 NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575
JBrowse link
G Csf1 colony stimulating factor 1 ISO MGI:MGI:1856333 (MGI:MGI:3640884|PMID:10804170) RGD PMID:10804170 MGI:MGI:3640884 NCBI chr 2:210,522,370...210,550,546
Ensembl chr 2:210,522,375...210,550,560
JBrowse link
G Kdm5b lysine demethylase 5B ISO MGI:MGI:4329395 (MGI:MGI:5619178|PMID:24802759) RGD PMID:24802759 MGI:MGI:5619178 NCBI chr13:51,384,371...51,455,392
Ensembl chr13:51,384,389...51,455,357
JBrowse link
G Mst1 macrophage stimulating 1 ISO MGI:MGI:2445230 (MGI:MGI:5614192|PMID:25049204) RGD PMID:25049204 MGI:MGI:5614192 NCBI chr 8:116,857,716...116,862,286
Ensembl chr 8:116,857,684...116,862,423
JBrowse link
G Robo1 roundabout guidance receptor 1 ISO MGI:MGI:3043142 (MGI:MGI:3617129|PMID:16439476) RGD PMID:16439476 MGI:MGI:3617129 NCBI chr11:9,079,291...10,146,302
Ensembl chr11:9,642,365...10,143,317
JBrowse link
G Slc12a2 solute carrier family 12 member 2 ISO MGI:MGI:1935144 (MGI:MGI:2180453|PMID:12040017) RGD PMID:12040017 MGI:MGI:2180453 NCBI chr18:52,917,124...52,985,281
Ensembl chr18:52,917,124...52,985,261
JBrowse link
G Slit2 slit guidance ligand 2 ISO MGI:MGI:2179460 (MGI:MGI:3617129|PMID:16439476) RGD PMID:16439476 MGI:MGI:3617129 NCBI chr14:66,831,848...67,171,491
Ensembl chr14:66,831,848...67,170,361
JBrowse link
mammary gland branching involved in pregnancy term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csmd1 CUB and Sushi multiple domains 1 ISO MGI:MGI:5473214 (MGI:MGI:6369467|PMID:31604923) RGD PMID:31604923 MGI:MGI:6369467 NCBI chr16:77,152,823...78,850,222
Ensembl chr16:78,539,489...78,850,222
JBrowse link
G Esr1 estrogen receptor 1 ISO
IEA
MGI:MGI:2150897 (MGI:MGI:1926565|PMID:10919287)
GO_REF:0000107
RGD
Ensembl
PMID:10919287 GO_REF:0000107, MGI:MGI:1926565 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Med1 mediator complex subunit 1 ISO MGI:MGI:3511276 (MGI:MGI:3576991|PMID:15647257) RGD PMID:15647257 MGI:MGI:3576991 NCBI chr10:86,101,560...86,145,271
Ensembl chr10:86,103,600...86,144,880
JBrowse link
G Vdr vitamin D receptor ISO
IEA
MGI:MGI:2183404 (MGI:MGI:3051725|PMID:15178742)
GO_REF:0000107
RGD
Ensembl
PMID:15178742 GO_REF:0000107, MGI:MGI:3051725 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166
JBrowse link
mammary gland branching involved in thelarche term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Areg amphiregulin ISO MGI:MGI:2176531 (MGI:MGI:1336843|PMID:10331984), (MGI:MGI:3703920|PMID:17369357) RGD PMID:10331984, PMID:17369357 MGI:MGI:1336843, MGI:MGI:3703920 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
JBrowse link
G Med1 mediator complex subunit 1 ISO MGI:MGI:3511276 (MGI:MGI:3576991|PMID:15647257) RGD PMID:15647257 MGI:MGI:3576991 NCBI chr10:86,101,560...86,145,271
Ensembl chr10:86,103,600...86,144,880
JBrowse link
G Ncoa3 nuclear receptor coactivator 3 ISO MGI:MGI:1931860 (MGI:MGI:1859522|PMID:11015591) RGD PMID:11015591 MGI:MGI:1859522 NCBI chr 3:162,692,176...162,788,582
Ensembl chr 3:162,692,185...162,787,548
JBrowse link
G Phb2 prohibitin 2 ISO MGI:MGI:3574361 (MGI:MGI:3695669|PMID:17065319) RGD PMID:17065319 MGI:MGI:3695669 NCBI chr 4:157,230,769...157,235,375
Ensembl chr 4:157,230,769...157,235,367
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO MGI:MGI:1857258 (MGI:MGI:3814777|PMID:18614704) RGD PMID:18614704 MGI:MGI:3814777 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Wnt5a Wnt family member 5A ISO
IEA
(MGI:MGI:3761053|PMID:17898001)
GO_REF:0000107
RGD
Ensembl
PMID:17898001 GO_REF:0000107, MGI:MGI:3761053 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
mammary gland bud elongation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pthlh parathyroid hormone-like hormone ISO MGI:MGI:2154515 (MGI:MGI:1203302|PMID:9477327) RGD PMID:9477327 MGI:MGI:1203302 NCBI chr 4:181,663,425...181,674,181 JBrowse link
mammary gland bud formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf10 fibroblast growth factor 10 ISO MGI:MGI:1859647 (MGI:MGI:2155478|PMID:11782400) RGD PMID:11782400 MGI:MGI:2155478 NCBI chr 2:51,673,480...51,747,533
Ensembl chr 2:51,672,722...51,750,369
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 ISO MGI:MGI:2153811 (MGI:MGI:2155478|PMID:11782400) RGD PMID:11782400 MGI:MGI:2155478 NCBI chr 1:200,590,951...200,696,946
Ensembl chr 1:200,590,953...200,696,928
JBrowse link
mammary gland bud morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sostdc1 sclerostin domain containing 1 ISO MGI:MGI:3604658 (MGI:MGI:5319554|PMID:22509524) RGD PMID:22509524 MGI:MGI:5319554 NCBI chr 6:55,812,820...55,816,994
Ensembl chr 6:55,812,747...55,817,066
JBrowse link
mammary gland duct morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli2 GLI family zinc finger 2 ISO MGI:MGI:1857509 (MGI:MGI:2151643|PMID:11783999) RGD PMID:11783999 MGI:MGI:2151643 NCBI chr13:34,829,021...35,049,172
Ensembl chr13:34,829,139...35,048,444
JBrowse link
G Lrp5 LDL receptor related protein 5 ISO MGI:MGI:1298218 (MGI:MGI:3849913|PMID:19503830) RGD PMID:19503830 MGI:MGI:3849913 NCBI chr 1:218,816,833...218,920,147
Ensembl chr 1:218,816,841...218,920,094
JBrowse link
G Lrp6 LDL receptor related protein 6 ISO MGI:MGI:1278315 (MGI:MGI:3849913|PMID:19503830) RGD PMID:19503830 MGI:MGI:3849913 NCBI chr 4:168,194,054...168,323,962
Ensembl chr 4:168,194,927...168,323,751
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 ISO MGI:MGI:1857745 (MGI:MGI:3758540|PMID:12198239) RGD PMID:12198239 MGI:MGI:3758540 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Ntn1 netrin 1 ISO
IEA
MGI:MGI:1315205 (MGI:MGI:3617129|PMID:16439476)
GO_REF:0000107
RGD
Ensembl
PMID:16439476 GO_REF:0000107, MGI:MGI:3617129 NCBI chr10:54,761,925...54,982,072
Ensembl chr10:54,761,871...54,967,585
JBrowse link
G Ptch1 patched 1 ISO MGI:MGI:1857447 (MGI:MGI:1346456|PMID:10529434) RGD PMID:10529434 MGI:MGI:1346456 NCBI chr17:1,032,242...1,085,885
Ensembl chr17:1,029,048...1,093,873
JBrowse link
G Scrib scribble planar cell polarity protein ISO (MGI:MGI:4359580|PMID:19041750) RGD PMID:19041750 MGI:MGI:4359580 NCBI chr 7:117,105,810...117,128,802
Ensembl chr 7:117,105,810...117,128,798
JBrowse link
G Slit2 slit guidance ligand 2 ISO MGI:MGI:105088|MGI:MGI:2179460 (MGI:MGI:3617129|PMID:16439476) RGD PMID:16439476 MGI:MGI:3617129 NCBI chr14:66,831,848...67,171,491
Ensembl chr14:66,831,848...67,170,361
JBrowse link
mammary gland epithelial cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cebpb CCAAT/enhancer binding protein beta ISO MGI:MGI:2149329 (MGI:MGI:1353872|PMID:10707954) RGD PMID:10707954 MGI:MGI:1353872 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Elf5 E74 like ETS transcription factor 5 ISO MGI:MGI:97763 (MGI:MGI:3623843|PMID:16469767) RGD PMID:16469767 MGI:MGI:3623843 NCBI chr 3:93,333,514...93,374,454
Ensembl chr 3:93,351,619...93,371,656
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:3689173|PMID:16837552)
Ensembl
UniProt
RGD
PMID:16837552 GO_REF:0000024, GO_REF:0000107, MGI:MGI:3689173 NCBI chr 9:75,021,790...76,178,936
Ensembl chr 9:75,021,790...75,528,644
JBrowse link
G Fgf2 fibroblast growth factor 2 ISO (MGI:MGI:49188|PMID:1376141) RGD PMID:1376141 MGI:MGI:49188 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Hoxa5 homeo box A5 ISO MGI:MGI:2150397 (MGI:MGI:3624927|PMID:16607641) RGD PMID:16607641 MGI:MGI:3624927
G Irf6 interferon regulatory factor 6 ISO (PMID:18212048) RGD PMID:18212048 NCBI chr13:111,870,121...111,889,328
Ensembl chr13:111,870,121...111,889,328
JBrowse link
G Lats1 large tumor suppressor kinase 1 ISO (PMID:28068668) RGD PMID:28068668 NCBI chr 1:1,784,078...1,817,310
Ensembl chr 1:1,784,078...1,817,310
JBrowse link
G Lbh LBH regulator of WNT signaling pathway ISO (MGI:MGI:5634223|PMID:25655704) RGD PMID:25655704 MGI:MGI:5634223 NCBI chr 6:24,154,207...24,184,217
Ensembl chr 6:24,160,226...24,181,866
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase IEP RGD PMID:16086375 RGD:2316910 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
JBrowse link
G Prlr prolactin receptor ISO MGI:MGI:1335079 (MGI:MGI:3623843|PMID:16469767) RGD PMID:16469767 MGI:MGI:3623843 NCBI chr 2:60,131,410...60,325,686
Ensembl chr 2:60,131,776...60,325,692
JBrowse link
G Ptch1 patched 1 ISO MGI:MGI:1857447 (MGI:MGI:1346456|PMID:10529434) RGD PMID:10529434 MGI:MGI:1346456 NCBI chr17:1,032,242...1,085,885
Ensembl chr17:1,029,048...1,093,873
JBrowse link
G Smo smoothened, frizzled class receptor ISO
IEA
MGI:MGI:1934268|MGI:MGI:2445832 (MGI:MGI:3696007|PMID:17199044)
GO_REF:0000107
RGD
Ensembl
PMID:17199044 GO_REF:0000107, MGI:MGI:3696007 NCBI chr 4:57,019,941...57,041,779
Ensembl chr 4:57,019,941...57,042,770
JBrowse link
G Zfp703 zinc finger protein 703 ISO (PMID:21337521) RGD PMID:21337521 NCBI chr16:69,237,857...69,242,028
Ensembl chr16:69,237,857...69,242,028
JBrowse link
mammary gland epithelial cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btrc beta-transducin repeat containing E3 ubiquitin protein ligase ISO MGI:MGI:3055737 (MGI:MGI:3054694|PMID:15340078) RGD PMID:15340078 MGI:MGI:3054694 NCBI chr 1:265,100,094...265,270,263
Ensembl chr 1:265,157,379...265,269,837
JBrowse link
G Ccnd1 cyclin D1 ISO MGI:MGI:99484 (MGI:MGI:3045614|PMID:11747812) RGD PMID:11747812 MGI:MGI:3045614 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta ISO MGI:MGI:2149329 (MGI:MGI:1353782|PMID:10683373) RGD PMID:10683373 MGI:MGI:1353782 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex ISO MGI:MGI:3045616|MGI:MGI:88313 (MGI:MGI:3045614|PMID:11747812) RGD PMID:11747812 MGI:MGI:3045614 NCBI chr 1:263,848,829...263,884,354
Ensembl chr 1:263,848,884...263,885,169
JBrowse link
G Epha2 Eph receptor A2 ISO (MGI:MGI:5284750|PMID:19321667) RGD PMID:19321667 MGI:MGI:5284750 NCBI chr 5:159,845,773...159,874,203
Ensembl chr 5:159,845,774...159,874,206
JBrowse link
G Id2 inhibitor of DNA binding 2 ISO
ISS
(MGI:MGI:2446740|PMID:12456807)
GO_REF:0000024
RGD
UniProt
PMID:12456807 GO_REF:0000024, MGI:MGI:2446740 NCBI chr 6:44,360,077...44,361,908
Ensembl chr 6:44,348,501...44,363,915
JBrowse link
G Mapk1 mitogen activated protein kinase 1 ISO (MGI:MGI:3835718|PMID:18604197) RGD PMID:18604197 MGI:MGI:3835718 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Med1 mediator complex subunit 1 ISO MGI:MGI:3511276|MGI:MGI:4443002 (MGI:MGI:3578445|PMID:15843544), (MGI:MGI:4442276|PMID:20351249) RGD PMID:15843544, PMID:20351249 MGI:MGI:3578445, MGI:MGI:4442276 NCBI chr10:86,101,560...86,145,271
Ensembl chr10:86,103,600...86,144,880
JBrowse link
G Stat6 signal transducer and activator of transcription 6 ISO MGI:MGI:1888385 (MGI:MGI:5424261|PMID:22588720) RGD PMID:22588720 MGI:MGI:5424261 NCBI chr 7:70,946,228...70,963,542
Ensembl chr 7:70,946,228...70,964,484
JBrowse link
G Tnfsf11 TNF superfamily member 11 ISO MGI:MGI:1859962 (MGI:MGI:1889907|PMID:11051546) RGD PMID:11051546 MGI:MGI:1889907 NCBI chr15:60,482,527...60,512,704
Ensembl chr15:60,482,527...60,512,704
JBrowse link
negative regulation of mammary gland epithelial cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca2 BRCA2, DNA repair associated IEA
ISO
GO_REF:0000107
(PMID:15930293)
Ensembl
RGD
PMID:15930293 GO_REF:0000107 NCBI chr12:503,660...544,754
Ensembl chr12:504,007...544,748
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO MGI:MGI:1926877 (MGI:MGI:3047035|PMID:15105443) RGD PMID:15105443 MGI:MGI:3047035 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Etv4 ETS variant transcription factor 4 ISO MGI:MGI:2445834 (MGI:MGI:3828920|PMID:18977342) RGD PMID:18977342 MGI:MGI:3828920 NCBI chr10:89,685,058...89,700,300
Ensembl chr10:89,685,058...89,700,283
JBrowse link
G Gata3 GATA binding protein 3 ISO (PMID:19483726) RGD PMID:19483726 NCBI chr17:72,419,752...72,452,043
Ensembl chr17:72,429,618...72,450,681
JBrowse link
G Phb2 prohibitin 2 ISO MGI:MGI:3574361 (MGI:MGI:3695669|PMID:17065319) RGD PMID:17065319 MGI:MGI:3695669 NCBI chr 4:157,230,769...157,235,375
Ensembl chr 4:157,230,769...157,235,367
JBrowse link
G Robo1 roundabout guidance receptor 1 ISO
IEA
(PMID:18829537)
GO_REF:0000107
RGD
Ensembl
PMID:18829537 GO_REF:0000107 NCBI chr11:9,079,291...10,146,302
Ensembl chr11:9,642,365...10,143,317
JBrowse link
positive regulation of mammary gland epithelial cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 ISO MGI:MGI:4439325|MGI:MGI:88313 (MGI:MGI:4438668|PMID:20075866) RGD PMID:20075866 MGI:MGI:4438668 NCBI chr 7:70,360,199...70,377,422
Ensembl chr 7:70,364,813...70,377,422
JBrowse link
G Ccnd1 cyclin D1 ISO MGI:MGI:3580016 (MGI:MGI:4438668|PMID:20075866) RGD PMID:20075866 MGI:MGI:4438668 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Iqgap3 IQ motif containing GTPase activating protein 3 ISO (MGI:MGI:3835718|PMID:18604197) RGD PMID:18604197 MGI:MGI:3835718 NCBI chr 2:187,447,477...187,489,630
Ensembl chr 2:187,447,501...187,489,630
JBrowse link
G Kdm5b lysine demethylase 5B ISO MGI:MGI:4329395 (MGI:MGI:5619178|PMID:24802759) RGD PMID:24802759 MGI:MGI:5619178 NCBI chr13:51,384,371...51,455,392
Ensembl chr13:51,384,389...51,455,357
JBrowse link
G Mst1 macrophage stimulating 1 ISO
IBA
MGI:MGI:2445230 (MGI:MGI:5614192|PMID:25049204)
PMID:21873635
RGD PMID:25049204, PMID:21873635 MGI:MGI:5614192, RGD:13792537 NCBI chr 8:116,857,716...116,862,286
Ensembl chr 8:116,857,684...116,862,423
JBrowse link
G Rreb1 ras responsive element binding protein 1 ISO (PMID:18394891) RGD PMID:18394891 NCBI chr17:27,539,137...27,718,878
Ensembl chr17:27,539,133...27,665,266
JBrowse link
G Rtn4 reticulon 4 IEA
ISO
GO_REF:0000107
(PMID:27353365)
Ensembl
RGD
PMID:27353365 GO_REF:0000107 NCBI chr14:114,126,931...114,174,459
Ensembl chr14:114,126,943...114,174,458
JBrowse link
G Zfp703 zinc finger protein 703 ISO (PMID:21337521)
(MGI:MGI:4940410|PMID:21317240)
RGD PMID:21317240, PMID:21337521 MGI:MGI:4940410 NCBI chr16:69,237,857...69,242,028
Ensembl chr16:69,237,857...69,242,028
JBrowse link
regulation of branching involved in mammary gland duct morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 ISO MGI:MGI:2180558 (MGI:MGI:3830397|PMID:19164602) RGD PMID:19164602 MGI:MGI:3830397 NCBI chr 4:144,382,945...144,398,919
Ensembl chr 4:144,382,945...144,398,917
JBrowse link
G Etv5 ETS variant transcription factor 5 ISO (MGI:MGI:2667785|PMID:12871699) RGD PMID:12871699 MGI:MGI:2667785 NCBI chr11:82,194,657...82,252,145
Ensembl chr11:82,194,657...82,252,139
JBrowse link
G Phb2 prohibitin 2 ISO MGI:MGI:3574361 (MGI:MGI:3695669|PMID:17065319) RGD PMID:17065319 MGI:MGI:3695669 NCBI chr 4:157,230,769...157,235,375
Ensembl chr 4:157,230,769...157,235,367
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO MGI:MGI:98958 (MGI:MGI:3761053|PMID:17898001) RGD PMID:17898001 MGI:MGI:3761053 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Wnt5a Wnt family member 5A ISO
IEA
MGI:MGI:96079|MGI:MGI:98725 (MGI:MGI:3761053|PMID:17898001)
GO_REF:0000107
RGD
Ensembl
PMID:17898001 GO_REF:0000107, MGI:MGI:3761053 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
regulation of mammary gland epithelial cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator ISO
IEA
MGI:MGI:1857429 (MGI:MGI:1337911|PMID:10363969)
GO_REF:0000107
RGD
Ensembl
PMID:10363969 GO_REF:0000107, MGI:MGI:1337911 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Deaf1 DEAF1 transcription factor IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:3822223|PMID:18826651)
(PMID:18826651)
Ensembl
UniProt
RGD
PMID:18826651 GO_REF:0000024, GO_REF:0000107, MGI:MGI:3822223 NCBI chr 1:214,283,787...214,317,466
Ensembl chr 1:214,283,790...214,317,466
JBrowse link
G Gpx1 glutathione peroxidase 1 ISO
IEA
(PMID:16945136)
GO_REF:0000107
RGD
Ensembl
PMID:16945136 GO_REF:0000107 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Hoxa5 homeo box A5 ISO MGI:MGI:2150397 (MGI:MGI:3624927|PMID:16607641) RGD PMID:16607641 MGI:MGI:3624927
G Pygo2 pygopus family PHD finger 2 ISO MGI:MGI:3711738 (MGI:MGI:4821247|PMID:19487454) RGD PMID:19487454 MGI:MGI:4821247 NCBI chr 2:188,757,167...188,762,285
Ensembl chr 2:188,757,489...188,762,282
JBrowse link
tertiary branching involved in mammary gland duct morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor ISO
IEA
MGI:MGI:2687199 (MGI:MGI:2683859|PMID:14676301)
GO_REF:0000107
RGD
Ensembl
PMID:14676301 GO_REF:0000107, MGI:MGI:2683859 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Pgr progesterone receptor ISO
IEA
MGI:MGI:1857933 (MGI:MGI:1354852|PMID:10733525)
GO_REF:0000107
RGD
Ensembl
PMID:10733525 GO_REF:0000107, MGI:MGI:1354852 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Wnt4 Wnt family member 4 ISO
IEA
MGI:MGI:1857453 (MGI:MGI:1354852|PMID:10733525)
GO_REF:0000107
RGD
Ensembl
PMID:10733525 GO_REF:0000107, MGI:MGI:1354852 NCBI chr 5:155,649,238...155,668,065
Ensembl chr 5:155,649,217...155,672,579
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    developmental process 6827
      anatomical structure development 6269
        tissue development 2099
          epithelium development 1263
            mammary gland epithelium development 84
              mammary gland duct morphogenesis + 44
              mammary gland epithelial cell differentiation + 17
              mammary gland epithelial cell proliferation + 32
Path 2
Term Annotations click to browse term
  biological_process 20028
    developmental process 6827
      anatomical structure development 6269
        multicellular organism development 5744
          system development 5280
            animal organ development 4035
              gland development 664
                mammary gland development 208
                  mammary gland epithelium development 84
                    mammary gland duct morphogenesis + 44
                    mammary gland epithelial cell differentiation + 17
                    mammary gland epithelial cell proliferation + 32
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.