ONTOLOGY REPORT - ANNOTATIONS


Term:mammary gland epithelium development
go back to main search page
Accession:GO:0061180 term browser browse the term
Definition:The process whose specific outcome is the progression of the mammary gland epithelium over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.
Synonyms:exact_synonym: breast epithelium development


show annotations for term's descendants       view all columns           Sort by:
 
mammary gland epithelium development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp2c2 ATPase secretory pathway Ca2+ transporting 2 JBrowse link 19 52,347,480 52,404,608 RGD:1624291
RGD:1600115
G Jak2 Janus kinase 2 JBrowse link 1 247,398,667 247,457,521 RGD:1624291
G Msx1 msh homeobox 1 JBrowse link 14 77,712,262 77,716,061 RGD:1624291
RGD:1600115
G Msx2 msh homeobox 2 JBrowse link 17 11,683,862 11,689,527 RGD:1624291
G Orai1 ORAI calcium release-activated calcium modulator 1 JBrowse link 12 38,981,903 38,995,570 RGD:1624291
RGD:1600115
G Prlr prolactin receptor JBrowse link 2 60,131,410 60,325,686 RGD:1624291
G Stat5a signal transducer and activator of transcription 5A JBrowse link 10 88,764,732 88,789,060 RGD:1624291
G Wnt2 Wnt family member 2 JBrowse link 4 45,286,845 45,332,899 RGD:1624291
RGD:1600115
G Wnt3 Wnt family member 3 JBrowse link 10 91,830,709 91,874,907 RGD:1624291
RGD:1600115
G Wnt4 Wnt family member 4 JBrowse link 5 155,649,238 155,668,065 RGD:1624291
G Wnt7b Wnt family member 7B JBrowse link 7 126,423,418 126,465,724 RGD:1624291
RGD:1600115
branch elongation involved in mammary gland duct branching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
RGD:1600115
branching involved in mammary gland duct morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Btrc beta-transducin repeat containing E3 ubiquitin protein ligase JBrowse link 1 265,100,094 265,270,263 RGD:1624291
RGD:1600115
G Ccl11 C-C motif chemokine ligand 11 JBrowse link 10 69,434,965 69,439,566 RGD:1624291
RGD:1600115
G Csf1 colony stimulating factor 1 JBrowse link 2 210,522,370 210,550,546 RGD:1624291
G Ddr1 discoidin domain receptor tyrosine kinase 1 JBrowse link 20 3,553,430 3,574,959 RGD:1624291
RGD:1600115
G Epha2 Eph receptor A2 JBrowse link 5 159,845,773 159,874,203 RGD:1624291
RGD:1600115
G Etv4 ets variant 4 JBrowse link 10 89,685,058 89,700,300 RGD:1624291
G Kdm5b lysine demethylase 5B JBrowse link 13 51,384,371 51,455,392 RGD:1624291
RGD:1600115
G Lrp5 LDL receptor related protein 5 JBrowse link 1 218,816,833 218,920,147 RGD:1624291
RGD:13792537
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291
RGD:13792537
G Msx2 msh homeobox 2 JBrowse link 17 11,683,862 11,689,527 RGD:1624291
RGD:1600115
G Pml promyelocytic leukemia JBrowse link 8 63,002,515 63,034,310 RGD:1624291
RGD:1600115
G Slc12a2 solute carrier family 12 member 2 JBrowse link 18 52,917,124 52,985,281 RGD:1624291
G Src SRC proto-oncogene, non-receptor tyrosine kinase JBrowse link 3 153,547,807 153,595,643 RGD:1624291
RGD:1600115
G Tbx3 T-box 3 JBrowse link 12 42,479,518 42,494,588 RGD:1624291
RGD:1600115
dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Areg amphiregulin JBrowse link 14 18,521,921 18,531,179 RGD:1624291
RGD:1600115
G Tfap2c transcription factor AP-2 gamma JBrowse link 3 170,550,314 170,558,197 RGD:1624291
epithelial cell differentiation involved in mammary gland alveolus development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxb1 forkhead box B1 JBrowse link 8 75,992,751 75,995,371 RGD:1624291
RGD:1600115
G Foxf1 forkhead box F1 JBrowse link 19 53,012,306 53,016,100 RGD:1624291
RGD:1600115
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:1624291
RGD:1600115
G Id2 inhibitor of DNA binding 2 JBrowse link 6 44,360,077 44,361,908 RGD:1624291
RGD:1600115
epithelial cell proliferation involved in mammary gland duct elongation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Areg amphiregulin JBrowse link 14 18,521,921 18,531,179 RGD:1624291
RGD:1600115
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:1624291
RGD:1600115
G Med1 mediator complex subunit 1 JBrowse link 10 86,101,560 86,145,271 RGD:1624291
RGD:1600115
G Tfap2c transcription factor AP-2 gamma JBrowse link 3 170,550,314 170,558,197 RGD:1624291
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
lateral sprouting involved in mammary gland duct morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:1624291
RGD:1600115
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
mammary duct terminal end bud growth term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl11 C-C motif chemokine ligand 11 JBrowse link 10 69,434,965 69,439,566 RGD:1624291
RGD:1600115
G Csf1 colony stimulating factor 1 JBrowse link 2 210,522,370 210,550,546 RGD:1624291
G Kdm5b lysine demethylase 5B JBrowse link 13 51,384,371 51,455,392 RGD:1624291
RGD:1600115
G Mst1 macrophage stimulating 1 JBrowse link 8 116,857,716 116,862,286 RGD:1624291
RGD:1600115
G Robo1 roundabout guidance receptor 1 JBrowse link 11 9,079,291 10,146,302 RGD:1624291
G Slc12a2 solute carrier family 12 member 2 JBrowse link 18 52,917,124 52,985,281 RGD:1624291
G Slit2 slit guidance ligand 2 JBrowse link 14 66,831,848 67,171,491 RGD:1624291
mammary gland branching involved in pregnancy term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:1624291
RGD:1600115
G Med1 mediator complex subunit 1 JBrowse link 10 86,101,560 86,145,271 RGD:1624291
RGD:1600115
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:1624291
RGD:1600115
mammary gland branching involved in thelarche term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Areg amphiregulin JBrowse link 14 18,521,921 18,531,179 RGD:1624291
RGD:1600115
G Med1 mediator complex subunit 1 JBrowse link 10 86,101,560 86,145,271 RGD:1624291
RGD:1600115
G Ncoa3 nuclear receptor coactivator 3 JBrowse link 3 162,692,176 162,788,582 RGD:1624291
G Phb2 prohibitin 2 JBrowse link 4 157,230,769 157,235,375 RGD:1624291
RGD:1600115
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
RGD:1600115
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
mammary gland bud elongation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pthlh parathyroid hormone-like hormone JBrowse link 4 181,663,425 181,674,181 RGD:1624291
mammary gland bud formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:1624291
RGD:1600115
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:1624291
mammary gland bud morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sostdc1 sclerostin domain containing 1 JBrowse link 6 55,812,820 55,816,994 RGD:1624291
RGD:1600115
mammary gland duct morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gli2 GLI family zinc finger 2 JBrowse link 13 34,829,021 35,049,172 RGD:1624291
G Lrp5 LDL receptor related protein 5 JBrowse link 1 218,816,833 218,920,147 RGD:1624291
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 JBrowse link 18 31,728,373 32,704,022 RGD:1624291
G Ntn1 netrin 1 JBrowse link 10 54,761,925 54,982,072 RGD:1624291
RGD:1600115
G Ptch1 patched 1 JBrowse link 17 1,032,242 1,085,885 RGD:1624291
RGD:1600115
G Scrib scribble planar cell polarity protein JBrowse link 7 117,105,810 117,128,802 RGD:1624291
RGD:1600115
G Slit2 slit guidance ligand 2 JBrowse link 14 66,831,848 67,171,491 RGD:1624291
mammary gland epithelial cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cebpb CCAAT/enhancer binding protein beta JBrowse link 3 164,424,502 164,425,933 RGD:1624291
RGD:1600115
G Elf5 E74 like ETS transcription factor 5 JBrowse link 3 93,333,514 93,374,454 RGD:1624291
RGD:1600115
G Erbb4 erb-b2 receptor tyrosine kinase 4 JBrowse link 9 75,021,790 76,178,936 RGD:1600115
RGD:1624291
G Fgf2 fibroblast growth factor 2 JBrowse link 2 124,081,072 124,134,133 RGD:1624291
RGD:1600115
G Hoxa5 homeo box A5 RGD:1624291
G Irf6 interferon regulatory factor 6 JBrowse link 13 111,870,121 111,889,328 RGD:1624291
RGD:1600115
G Lats1 large tumor suppressor kinase 1 JBrowse link 1 1,784,078 1,817,310 RGD:1624291
RGD:1600115
G Lbh LBH regulator of WNT signaling pathway JBrowse link 6 24,154,207 24,184,217 RGD:1624291
RGD:1600115
G Mgmt O-6-methylguanine-DNA methyltransferase JBrowse link 1 209,237,255 209,464,189 RGD:2316910
G Prlr prolactin receptor JBrowse link 2 60,131,410 60,325,686 RGD:1624291
G Ptch1 patched 1 JBrowse link 17 1,032,242 1,085,885 RGD:1624291
RGD:1600115
G Smo smoothened, frizzled class receptor JBrowse link 4 57,019,941 57,041,779 RGD:1624291
RGD:1600115
G Zfp703 zinc finger protein 703 JBrowse link 16 69,237,857 69,242,028 RGD:1624291
RGD:1600115
mammary gland epithelial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Btrc beta-transducin repeat containing E3 ubiquitin protein ligase JBrowse link 1 265,100,094 265,270,263 RGD:1624291
RGD:1600115
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:1624291
RGD:1600115
G Cebpb CCAAT/enhancer binding protein beta JBrowse link 3 164,424,502 164,425,933 RGD:1624291
RGD:1600115
G Chuk component of inhibitor of nuclear factor kappa B kinase complex JBrowse link 1 263,848,829 263,884,354 RGD:1624291
G Epha2 Eph receptor A2 JBrowse link 5 159,845,773 159,874,203 RGD:1624291
RGD:1600115
G Id2 inhibitor of DNA binding 2 JBrowse link 6 44,360,077 44,361,908 RGD:1624291
RGD:1600115
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:1624291
RGD:1600115
G Med1 mediator complex subunit 1 JBrowse link 10 86,101,560 86,145,271 RGD:1624291
G Stat6 signal transducer and activator of transcription 6 JBrowse link 7 70,946,228 70,963,542 RGD:1624291
RGD:1600115
G Tnfsf11 TNF superfamily member 11 JBrowse link 15 60,482,527 60,512,704 RGD:1624291
negative regulation of mammary gland epithelial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Brca2 BRCA2, DNA repair associated JBrowse link 12 503,660 544,754 RGD:1600115
RGD:1624291
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:1624291
G Etv4 ets variant 4 JBrowse link 10 89,685,058 89,700,300 RGD:1624291
G Gata3 GATA binding protein 3 JBrowse link 17 72,419,752 72,452,043 RGD:1624291
RGD:1600115
G Phb2 prohibitin 2 JBrowse link 4 157,230,769 157,235,375 RGD:1624291
RGD:1600115
G Robo1 roundabout guidance receptor 1 JBrowse link 11 9,079,291 10,146,302 RGD:1624291
RGD:1600115
positive regulation of mammary gland epithelial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 JBrowse link 7 70,360,199 70,377,422 RGD:1624291
RGD:1600115
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:1624291
RGD:1600115
G Iqgap3 IQ motif containing GTPase activating protein 3 JBrowse link 2 187,447,477 187,489,630 RGD:1624291
RGD:1600115
G Kdm5b lysine demethylase 5B JBrowse link 13 51,384,371 51,455,392 RGD:1624291
RGD:1600115
G Mst1 macrophage stimulating 1 JBrowse link 8 116,857,716 116,862,286 RGD:1624291
RGD:13792537
G Rreb1 ras responsive element binding protein 1 JBrowse link 17 27,539,137 27,718,878 RGD:1624291
RGD:1600115
G Rtn4 reticulon 4 JBrowse link 14 114,126,931 114,174,459 RGD:1600115
RGD:1624291
G Zfp703 zinc finger protein 703 JBrowse link 16 69,237,857 69,242,028 RGD:1624291
RGD:1600115
regulation of branching involved in mammary gland duct morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cav3 caveolin 3 JBrowse link 4 144,382,945 144,398,919 RGD:1624291
RGD:1600115
G Etv5 ets variant 5 JBrowse link 11 82,194,657 82,252,145 RGD:1624291
RGD:1600115
G Phb2 prohibitin 2 JBrowse link 4 157,230,769 157,235,375 RGD:1624291
RGD:1600115
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
RGD:1600115
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
regulation of mammary gland epithelial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:1624291
RGD:1600115
G Deaf1 DEAF1 transcription factor JBrowse link 1 214,283,787 214,317,466 RGD:1600115
RGD:1624291
G Gpx1 glutathione peroxidase 1 JBrowse link 8 117,117,430 117,118,528 RGD:1624291
RGD:1600115
G Hoxa5 homeo box A5 RGD:1624291
G Pygo2 pygopus family PHD finger 2 JBrowse link 2 188,757,167 188,762,285 RGD:1624291
RGD:1600115
tertiary branching involved in mammary gland duct morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:1624291
RGD:1600115
G Pgr progesterone receptor JBrowse link 8 7,128,656 7,187,796 RGD:1624291
RGD:1600115
G Wnt4 Wnt family member 4 JBrowse link 5 155,649,238 155,668,065 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17941
    developmental process 6374
      anatomical structure development 5982
        tissue development 2021
          epithelium development 1194
            mammary gland epithelium development 80
              mammary gland duct morphogenesis + 40
              mammary gland epithelial cell differentiation + 17
              mammary gland epithelial cell proliferation + 32
Path 2
Term Annotations click to browse term
  biological_process 17941
    developmental process 6374
      anatomical structure development 5982
        multicellular organism development 5475
          system development 5028
            animal organ development 3847
              gland development 645
                mammary gland development 199
                  mammary gland epithelium development 80
                    mammary gland duct morphogenesis + 40
                    mammary gland epithelial cell differentiation + 17
                    mammary gland epithelial cell proliferation + 32
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.