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ONTOLOGY REPORT - ANNOTATIONS


Term:mammary gland epithelium development
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Accession:GO:0061180 term browser browse the term
Definition:The process whose specific outcome is the progression of the mammary gland epithelium over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.
Synonyms:exact_synonym: breast epithelium development


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mammary gland epithelium development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP2C2 ATPase secretory pathway Ca2+ transporting 2 ISO (MGI:5528587|PMID:23840669) MGI PMID:23840669 MGI:5528587 NCBI chr16:65,033,470...65,127,403
Ensembl chr16:84,375,658...84,468,671
JBrowse link
G JAK2 Janus kinase 2 ISO (MGI:2180453|PMID:12040017) MGI PMID:12040017 MGI:2180453 NCBI chr 9:4,820,303...4,971,867
Ensembl chr 9:5,006,271...5,156,626
JBrowse link
G LOC100988550 signal transducer and activator of transcription 5A ISO (MGI:2180453|PMID:12040017) MGI PMID:12040017 MGI:2180453 NCBI chr17:15,005,025...15,029,110
Ensembl chr17:15,228,465...15,251,783
JBrowse link
G MSX1 msh homeobox 1 ISO (MGI:1355063|PMID:10742104) MGI PMID:10742104 MGI:1355063 Ensembl chr 4:4,935,600...4,939,079 JBrowse link
G MSX2 msh homeobox 2 ISO (MGI:1355063|PMID:10742104) MGI PMID:10742104 MGI:1355063 NCBI chr 5:170,063,137...170,070,226
Ensembl chr 5:176,967,902...176,976,609
JBrowse link
G ORAI1 ORAI calcium release-activated calcium modulator 1 ISO (MGI:5528587|PMID:23840669) MGI PMID:23840669 MGI:5528587 NCBI chr12:119,229,069...119,243,435 JBrowse link
G PRLR prolactin receptor ISO (MGI:2180453|PMID:12040017) MGI PMID:12040017 MGI:2180453 NCBI chr 5:75,139,852...75,321,695
Ensembl chr 5:80,532,058...80,600,403
JBrowse link
G WNT2 Wnt family member 2 ISO (PMID:8168088) UniProtKB PMID:8168088 NCBI chr 7:109,244,772...109,291,472
Ensembl chr 7:121,936,031...121,985,862
JBrowse link
G WNT4 Wnt family member 4 ISO (PMID:8168088) UniProtKB PMID:8168088 NCBI chr 1:21,310,228...21,335,985
Ensembl chr 1:22,255,056...22,268,801
JBrowse link
G WNT7B Wnt family member 7B ISO (PMID:8168088) UniProtKB PMID:8168088 Ensembl chr22:44,988,647...45,044,841 JBrowse link
branch elongation involved in mammary gland duct branching term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TGFB1 transforming growth factor beta 1 ISO (MGI:3814777|PMID:18614704) MGI PMID:18614704 MGI:3814777 NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973
JBrowse link
branching involved in mammary gland duct morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTRC beta-transducin repeat containing E3 ubiquitin protein ligase ISO (MGI:3054694|PMID:15340078) MGI PMID:15340078 MGI:3054694 NCBI chr10:97,958,527...98,159,550
Ensembl chr10:101,431,318...101,632,496
JBrowse link
G CSF1 colony stimulating factor 1 ISO (MGI:3640884|PMID:10804170) MGI PMID:10804170 MGI:3640884 NCBI chr 1:112,555,755...112,575,894
Ensembl chr 1:127,764,916...127,781,943
JBrowse link
G DDR1 discoidin domain receptor tyrosine kinase 1 ISO (MGI:1932625|PMID:11283268) MGI PMID:11283268 MGI:1932625 NCBI chr 6:30,625,871...30,645,066
Ensembl chr 6:31,496,047...31,513,455
JBrowse link
G EPHA2 EPH receptor A2 ISO (MGI:5284750|PMID:19321667) UniProt PMID:19321667 MGI:5284750 NCBI chr 1:15,259,915...15,292,983
Ensembl chr 1:16,253,513...16,284,787
JBrowse link
G ETV4 ETS variant transcription factor 4 ISO (MGI:3828920|PMID:18977342)
(MGI:2667785|PMID:12871699)
MGI PMID:12871699, PMID:18977342 MGI:2667785, MGI:3828920 NCBI chr17:13,850,823...13,869,347
Ensembl chr17:14,099,160...14,116,186
JBrowse link
G KDM5B lysine demethylase 5B ISO (MGI:5619178|PMID:24802759) MGI PMID:24802759 MGI:5619178 NCBI chr 1:178,323,073...178,406,608
Ensembl chr 1:182,622,425...182,702,994
JBrowse link
G LRP5 LDL receptor related protein 5 ISO (MGI:3692480|PMID:16973609) MGI PMID:16973609 MGI:3692480 NCBI chr11:63,396,511...63,534,471
Ensembl chr11:66,735,246...66,839,817
JBrowse link
G LRP6 LDL receptor related protein 6 ISO (MGI:3849913|PMID:19503830) MGI PMID:19503830 MGI:3849913 NCBI chr12:12,121,411...12,288,590
Ensembl chr12:12,508,108...12,657,973
JBrowse link
G MSX2 msh homeobox 2 ISO (MGI:1355063|PMID:10742104) MGI PMID:10742104 MGI:1355063 NCBI chr 5:170,063,137...170,070,226
Ensembl chr 5:176,967,902...176,976,609
JBrowse link
G PML PML nuclear body scaffold ISO (MGI:3839212|PMID:19261859) MGI PMID:19261859 MGI:3839212 NCBI chr15:52,903,874...52,955,151
Ensembl chr15:71,658,884...71,710,883
JBrowse link
G SLC12A2 solute carrier family 12 member 2 ISO (MGI:2180693|PMID:8864124) MGI PMID:8864124 MGI:2180693 NCBI chr 5:123,499,267...123,603,777
Ensembl chr 5:129,262,134...129,364,563
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO (MGI:3589531|PMID:16007215) MGI PMID:16007215 MGI:3589531 NCBI chr20:33,667,614...33,727,126
Ensembl chr20:34,822,271...34,839,634
JBrowse link
G TBX3 T-box transcription factor 3 ISO (MGI:3608166|PMID:16222716) MGI PMID:16222716 MGI:3608166 NCBI chr12:112,240,050...112,254,299
Ensembl chr12:115,620,002...115,631,316
JBrowse link
dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AREG amphiregulin ISO (MGI:3703920|PMID:17369357) MGI PMID:17369357 MGI:3703920 NCBI chr 4:49,737,191...49,747,013 JBrowse link
G TFAP2C transcription factor AP-2 gamma ISO (MGI:4422106|PMID:20131354) MGI PMID:20131354 MGI:4422106 NCBI chr20:52,966,907...52,981,024
Ensembl chr20:54,255,489...54,265,432
JBrowse link
epithelial cell differentiation involved in mammary gland alveolus development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXB1 forkhead box B1 ISO (MGI:1931655|PMID:11170346) UniProt PMID:11170346 MGI:1931655 NCBI chr15:38,979,727...38,983,040
Ensembl chr15:57,284,077...57,285,054
JBrowse link
G FOXF1 forkhead box F1 ISO (MGI:3640953|PMID:16691571) MGI PMID:16691571 MGI:3640953 NCBI chr16:67,183,416...67,188,211
Ensembl chr16:86,516,119...86,519,949
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO (MGI:2654263|PMID:12620994) MGI PMID:12620994 MGI:2654263 NCBI chr14:42,295,691...42,348,478
Ensembl chr14:60,552,374...60,604,885
JBrowse link
G ID2 inhibitor of DNA binding 2 ISO (MGI:2446740|PMID:12456807) UniProt PMID:12456807 MGI:2446740 NCBI chr2A:8,681,592...8,684,014
Ensembl chr2A:8,847,776...8,850,720
JBrowse link
epithelial cell proliferation involved in mammary gland duct elongation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AREG amphiregulin ISO (MGI:3703920|PMID:17369357) MGI PMID:17369357 MGI:3703920 NCBI chr 4:49,737,191...49,747,013 JBrowse link
G ESR1 estrogen receptor 1 ISO (MGI:3629536|PMID:12021201) MGI PMID:12021201 MGI:3629536 NCBI chr 6:149,507,599...149,918,523
Ensembl chr 6:154,317,002...154,631,551
JBrowse link
G MED1 mediator complex subunit 1 ISO (MGI:3576991|PMID:15647257) MGI PMID:15647257 MGI:3576991 NCBI chr17:17,836,350...17,883,610
Ensembl chr17:18,050,474...18,095,118
JBrowse link
G TFAP2C transcription factor AP-2 gamma ISO (MGI:4422106|PMID:20131354) MGI PMID:20131354 MGI:4422106 NCBI chr20:52,966,907...52,981,024
Ensembl chr20:54,255,489...54,265,432
JBrowse link
G WNT5A Wnt family member 5A ISO (MGI:3761053|PMID:17898001) MGI PMID:17898001 MGI:3761053 NCBI chr 3:55,396,279...55,418,579
Ensembl chr 3:56,621,380...56,638,051
JBrowse link
lateral sprouting involved in mammary gland duct morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AR androgen receptor ISO (MGI:2683859|PMID:14676301) MGI PMID:14676301 MGI:2683859 NCBI chr  X:56,722,828...56,909,004
Ensembl chr  X:66,791,081...66,969,357
JBrowse link
G WNT5A Wnt family member 5A ISO (MGI:3761053|PMID:17898001) MGI PMID:17898001 MGI:3761053 NCBI chr 3:55,396,279...55,418,579
Ensembl chr 3:56,621,380...56,638,051
JBrowse link
mammary duct terminal end bud growth term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CSF1 colony stimulating factor 1 ISO (MGI:3640884|PMID:10804170) MGI PMID:10804170 MGI:3640884 NCBI chr 1:112,555,755...112,575,894
Ensembl chr 1:127,764,916...127,781,943
JBrowse link
G KDM5B lysine demethylase 5B ISO (MGI:5619178|PMID:24802759) MGI PMID:24802759 MGI:5619178 NCBI chr 1:178,323,073...178,406,608
Ensembl chr 1:182,622,425...182,702,994
JBrowse link
G MST1 macrophage stimulating 1 ISO (MGI:5614192|PMID:25049204) MGI PMID:25049204 MGI:5614192 NCBI chr 3:49,616,339...49,621,749 JBrowse link
G ROBO1 roundabout guidance receptor 1 ISO (MGI:3617129|PMID:16439476) MGI PMID:16439476 MGI:3617129 NCBI chr 3:78,707,802...79,876,519
Ensembl chr 3:80,581,388...81,569,308
JBrowse link
G SLC12A2 solute carrier family 12 member 2 ISO (MGI:2180453|PMID:12040017) MGI PMID:12040017 MGI:2180453 NCBI chr 5:123,499,267...123,603,777
Ensembl chr 5:129,262,134...129,364,563
JBrowse link
G SLIT2 slit guidance ligand 2 ISO (MGI:3617129|PMID:16439476) MGI PMID:16439476 MGI:3617129 NCBI chr 4:14,654,448...15,023,708
Ensembl chr 4:20,158,952...20,314,656
JBrowse link
mammary gland branching involved in pregnancy term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CSMD1 CUB and Sushi multiple domains 1 ISO (MGI:6369467|PMID:31604923) MGI PMID:31604923 MGI:6369467 NCBI chr 8:2,282,763...4,351,724
Ensembl chr 8:2,838,803...4,923,373
JBrowse link
G ESR1 estrogen receptor 1 ISO (MGI:1926565|PMID:10919287) MGI PMID:10919287 MGI:1926565 NCBI chr 6:149,507,599...149,918,523
Ensembl chr 6:154,317,002...154,631,551
JBrowse link
G MED1 mediator complex subunit 1 ISO (MGI:3576991|PMID:15647257) MGI PMID:15647257 MGI:3576991 NCBI chr17:17,836,350...17,883,610
Ensembl chr17:18,050,474...18,095,118
JBrowse link
G VDR vitamin D receptor ISO (MGI:3051725|PMID:15178742) MGI PMID:15178742 MGI:3051725 NCBI chr12:40,828,413...40,891,700
Ensembl chr12:41,702,742...41,766,192
JBrowse link
mammary gland branching involved in thelarche term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AREG amphiregulin ISO (MGI:1336843|PMID:10331984), (MGI:3703920|PMID:17369357) MGI PMID:10331984, PMID:17369357 MGI:1336843, MGI:3703920 NCBI chr 4:49,737,191...49,747,013 JBrowse link
G MED1 mediator complex subunit 1 ISO (MGI:3576991|PMID:15647257) MGI PMID:15647257 MGI:3576991 NCBI chr17:17,836,350...17,883,610
Ensembl chr17:18,050,474...18,095,118
JBrowse link
G NCOA3 nuclear receptor coactivator 3 ISO (MGI:1859522|PMID:11015591) MGI PMID:11015591 MGI:1859522 NCBI chr20:43,838,227...43,992,407
Ensembl chr20:45,000,422...45,073,549
JBrowse link
G PHB2 prohibitin 2 ISO (MGI:3695669|PMID:17065319) MGI PMID:17065319 MGI:3695669 NCBI chr12:7,097,073...7,102,474
Ensembl chr12:7,013,195...7,018,053
JBrowse link
G TGFB1 transforming growth factor beta 1 ISO (MGI:3814777|PMID:18614704) MGI PMID:18614704 MGI:3814777 NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973
JBrowse link
G WNT5A Wnt family member 5A ISO (MGI:3761053|PMID:17898001) MGI PMID:17898001 MGI:3761053 NCBI chr 3:55,396,279...55,418,579
Ensembl chr 3:56,621,380...56,638,051
JBrowse link
mammary gland bud elongation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTHLH parathyroid hormone like hormone ISO (MGI:1203302|PMID:9477327) MGI PMID:9477327 MGI:1203302 NCBI chr12:58,341,361...58,355,804
Ensembl chr12:60,960,071...60,973,750
JBrowse link
mammary gland bud formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGF10 fibroblast growth factor 10 ISO (MGI:2155478|PMID:11782400) MGI PMID:11782400 MGI:2155478 NCBI chr 5:65,979,443...66,069,314
Ensembl chr 5:71,028,187...71,111,706
JBrowse link
G FGFR2 fibroblast growth factor receptor 2 ISO (MGI:2155478|PMID:11782400) MGI PMID:11782400 MGI:2155478 NCBI chr10:118,055,854...118,175,440
Ensembl chr10:121,469,735...121,588,815
JBrowse link
mammary gland bud morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SOSTDC1 sclerostin domain containing 1 ISO (MGI:5319554|PMID:22509524) MGI PMID:22509524 MGI:5319554 NCBI chr 7:17,116,828...17,121,142
Ensembl chr 7:16,443,703...16,448,076
JBrowse link
mammary gland duct morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLI2 GLI family zinc finger 2 ISO (MGI:2151643|PMID:11783999) MGI PMID:11783999 MGI:2151643 NCBI chr2B:7,665,403...7,922,840
Ensembl chr2B:121,303,831...121,497,442
JBrowse link
G LRP5 LDL receptor related protein 5 ISO (MGI:3849913|PMID:19503830) MGI PMID:19503830 MGI:3849913 NCBI chr11:63,396,511...63,534,471
Ensembl chr11:66,735,246...66,839,817
JBrowse link
G LRP6 LDL receptor related protein 6 ISO (MGI:3849913|PMID:19503830) MGI PMID:19503830 MGI:3849913 NCBI chr12:12,121,411...12,288,590
Ensembl chr12:12,508,108...12,657,973
JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 ISO (MGI:3758540|PMID:12198239) MGI PMID:12198239 MGI:3758540 NCBI chr 5:138,634,278...139,089,171
Ensembl chr 5:144,741,452...144,865,269
JBrowse link
G NTN1 netrin 1 ISO (MGI:3617129|PMID:16439476) MGI PMID:16439476 MGI:3617129 NCBI chr17:42,409,797...42,631,930
Ensembl chr17:47,152,225...47,368,134
JBrowse link
G PTCH1 patched 1 ISO (MGI:1346456|PMID:10529434) MGI PMID:10529434 MGI:1346456 NCBI chr 9:66,542,675...66,616,820
Ensembl chr 9:94,668,365...94,741,453
JBrowse link
G SCRIB scribble planar cell polarity protein ISO (MGI:4359580|PMID:19041750) UniProt PMID:19041750 MGI:4359580 NCBI chr 8:140,544,797...140,571,078
Ensembl chr 8:143,557,722...143,582,353
JBrowse link
G SLIT2 slit guidance ligand 2 ISO (MGI:3617129|PMID:16439476) MGI PMID:16439476 MGI:3617129 NCBI chr 4:14,654,448...15,023,708
Ensembl chr 4:20,158,952...20,314,656
JBrowse link
mammary gland epithelial cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CEBPB CCAAT enhancer binding protein beta ISO (MGI:1353872|PMID:10707954) MGI PMID:10707954 MGI:1353872 NCBI chr20:46,533,163...46,535,282 JBrowse link
G ELF5 E74 like ETS transcription factor 5 ISO (MGI:3623843|PMID:16469767) MGI PMID:16469767 MGI:3623843 NCBI chr11:34,453,550...34,486,519
Ensembl chr11:34,329,889...34,362,770
JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 ISO (MGI:3689173|PMID:16837552) UniProt PMID:16837552 MGI:3689173 NCBI chr2B:98,625,630...99,795,371
Ensembl chr2B:217,069,644...218,272,006
JBrowse link
G FGF2 fibroblast growth factor 2 ISO (MGI:49188|PMID:1376141) MGI PMID:1376141 MGI:49188 NCBI chr 4:115,005,136...115,076,369
Ensembl chr 4:126,149,813...126,214,942
JBrowse link
G HOXA5 homeobox A5 ISO (MGI:3624927|PMID:16607641) MGI PMID:16607641 MGI:3624927 NCBI chr 7:27,786,040...27,789,339
Ensembl chr 7:27,385,175...27,388,990
JBrowse link
G IRF6 interferon regulatory factor 6 ISO (PMID:18212048) UniProtKB PMID:18212048 NCBI chr 1:185,361,612...185,382,516
Ensembl chr 1:190,226,727...190,247,145
JBrowse link
G LATS1 large tumor suppressor kinase 1 ISO (PMID:28068668) UniProtKB PMID:28068668 NCBI chr 6:147,476,913...147,533,491
Ensembl chr 6:152,182,394...152,239,276
JBrowse link
G LBH LBH regulator of WNT signaling pathway ISO (MGI:5634223|PMID:25655704) CAFA PMID:25655704 MGI:5634223 NCBI chr2A:30,244,474...30,273,048
Ensembl chr2A:30,320,249...30,411,779
JBrowse link
G MGMT O-6-methylguanine-DNA methyltransferase ISO RGD PMID:16086375 RGD:2316910 NCBI chr10:126,059,701...126,365,850
Ensembl chr10:130,305,485...130,609,422
JBrowse link
G PRLR prolactin receptor ISO (MGI:3623843|PMID:16469767) MGI PMID:16469767 MGI:3623843 NCBI chr 5:75,139,852...75,321,695
Ensembl chr 5:80,532,058...80,600,403
JBrowse link
G PTCH1 patched 1 ISO (MGI:1346456|PMID:10529434) MGI PMID:10529434 MGI:1346456 NCBI chr 9:66,542,675...66,616,820
Ensembl chr 9:94,668,365...94,741,453
JBrowse link
G SMO smoothened, frizzled class receptor ISO (MGI:3696007|PMID:17199044) MGI PMID:17199044 MGI:3696007 NCBI chr 7:121,143,968...121,168,873
Ensembl chr 7:133,668,304...133,693,048
JBrowse link
G ZNF703 zinc finger protein 703 ISO (PMID:21337521) UniProtKB PMID:21337521 NCBI chr 8:36,994,222...36,998,462 JBrowse link
mammary gland epithelial cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTRC beta-transducin repeat containing E3 ubiquitin protein ligase ISO (MGI:3054694|PMID:15340078) MGI PMID:15340078 MGI:3054694 NCBI chr10:97,958,527...98,159,550
Ensembl chr10:101,431,318...101,632,496
JBrowse link
G CCND1 cyclin D1 ISO (MGI:3045614|PMID:11747812) MGI PMID:11747812 MGI:3045614 NCBI chr11:64,737,006...64,750,353 JBrowse link
G CEBPB CCAAT enhancer binding protein beta ISO (MGI:1353782|PMID:10683373) MGI PMID:10683373 MGI:1353782 NCBI chr20:46,533,163...46,535,282 JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex ISO (MGI:3045614|PMID:11747812) MGI PMID:11747812 MGI:3045614 NCBI chr10:96,794,228...96,835,449
Ensembl chr10:100,280,490...100,316,918
JBrowse link
G EPHA2 EPH receptor A2 ISO (MGI:5284750|PMID:19321667) UniProt PMID:19321667 MGI:5284750 NCBI chr 1:15,259,915...15,292,983
Ensembl chr 1:16,253,513...16,284,787
JBrowse link
G ID2 inhibitor of DNA binding 2 ISO (MGI:2446740|PMID:12456807) UniProt PMID:12456807 MGI:2446740 NCBI chr2A:8,681,592...8,684,014
Ensembl chr2A:8,847,776...8,850,720
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 ISO (MGI:3835718|PMID:18604197) MGI PMID:18604197 MGI:3835718 NCBI chr22:3,883,119...3,990,368
Ensembl chr22:20,365,487...20,450,335
JBrowse link
G MED1 mediator complex subunit 1 ISO (MGI:4442276|PMID:20351249)
(MGI:3578445|PMID:15843544)
MGI PMID:15843544, PMID:20351249 MGI:3578445, MGI:4442276 NCBI chr17:17,836,350...17,883,610
Ensembl chr17:18,050,474...18,095,118
JBrowse link
G TNFSF11 TNF superfamily member 11 ISO (MGI:1889907|PMID:11051546) MGI PMID:11051546 MGI:1889907 NCBI chr13:23,750,835...23,784,740 JBrowse link
negative regulation of mammary gland epithelial cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRCA2 BRCA2 DNA repair associated ISO (PMID:15930293) UniProtKB PMID:15930293 NCBI chr13:13,574,422...13,658,967
Ensembl chr13:32,010,066...32,091,332
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A ISO (MGI:3047035|PMID:15105443) MGI PMID:15105443 MGI:3047035 NCBI chr 9:21,803,862...21,831,322 JBrowse link
G ETV4 ETS variant transcription factor 4 ISO (MGI:3828920|PMID:18977342) MGI PMID:18977342 MGI:3828920 NCBI chr17:13,850,823...13,869,347
Ensembl chr17:14,099,160...14,116,186
JBrowse link
G GATA3 GATA binding protein 3 ISO (PMID:19483726) UniProtKB PMID:19483726 NCBI chr10:8,075,951...8,105,573
Ensembl chr10:8,064,207...8,086,272
JBrowse link
G PHB2 prohibitin 2 ISO (MGI:3695669|PMID:17065319) MGI PMID:17065319 MGI:3695669 NCBI chr12:7,097,073...7,102,474
Ensembl chr12:7,013,195...7,018,053
JBrowse link
G ROBO1 roundabout guidance receptor 1 ISO (PMID:18829537) BHF-UCL PMID:18829537 NCBI chr 3:78,707,802...79,876,519
Ensembl chr 3:80,581,388...81,569,308
JBrowse link
positive regulation of mammary gland epithelial cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 ISO (MGI:4438668|PMID:20075866) MGI PMID:20075866 MGI:4438668 NCBI chr12:31,187,821...31,201,594 JBrowse link
G CCND1 cyclin D1 ISO (MGI:4438668|PMID:20075866) MGI PMID:20075866 MGI:4438668 NCBI chr11:64,737,006...64,750,353 JBrowse link
G IQGAP3 IQ motif containing GTPase activating protein 3 ISO (MGI:3835718|PMID:18604197) MGI PMID:18604197 MGI:3835718 NCBI chr 1:131,869,002...131,916,554
Ensembl chr 1:135,695,602...135,740,564
JBrowse link
G KDM5B lysine demethylase 5B ISO (MGI:5619178|PMID:24802759) MGI PMID:24802759 MGI:5619178 NCBI chr 1:178,323,073...178,406,608
Ensembl chr 1:182,622,425...182,702,994
JBrowse link
G MST1 macrophage stimulating 1 ISO (MGI:5614192|PMID:25049204) MGI PMID:25049204 MGI:5614192 NCBI chr 3:49,616,339...49,621,749 JBrowse link
G RREB1 ras responsive element binding protein 1 ISO (PMID:18394891) UniProtKB PMID:18394891 NCBI chr 6:6,945,205...7,089,757
Ensembl chr 6:7,257,875...7,356,544
JBrowse link
G RTN4 reticulon 4 ISO (PMID:27353365) CAFA PMID:27353365 NCBI chr2A:55,129,272...55,207,031 JBrowse link
G ZNF703 zinc finger protein 703 ISO (PMID:21337521)
(MGI:4940410|PMID:21317240)
UniProtKB
UniProt
PMID:21317240, PMID:21337521 MGI:4940410 NCBI chr 8:36,994,222...36,998,462 JBrowse link
regulation of branching involved in mammary gland duct morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAV3 caveolin 3 ISO (MGI:3830397|PMID:19164602) MGI PMID:19164602 MGI:3830397 NCBI chr 3:8,684,829...8,697,731
Ensembl chr 3:8,928,069...8,940,942
JBrowse link
G ETV5 ETS variant transcription factor 5 ISO (MGI:2667785|PMID:12871699) MGI PMID:12871699 MGI:2667785 NCBI chr 3:183,076,677...183,139,886
Ensembl chr 3:191,545,915...191,606,550
JBrowse link
G PHB2 prohibitin 2 ISO (MGI:3695669|PMID:17065319) MGI PMID:17065319 MGI:3695669 NCBI chr12:7,097,073...7,102,474
Ensembl chr12:7,013,195...7,018,053
JBrowse link
G TGFB1 transforming growth factor beta 1 ISO (MGI:3761053|PMID:17898001) MGI PMID:17898001 MGI:3761053 NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973
JBrowse link
G WNT5A Wnt family member 5A ISO (MGI:3761053|PMID:17898001) MGI PMID:17898001 MGI:3761053 NCBI chr 3:55,396,279...55,418,579
Ensembl chr 3:56,621,380...56,638,051
JBrowse link
regulation of mammary gland epithelial cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator ISO (MGI:1337911|PMID:10363969) MGI PMID:10363969 MGI:1337911 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468
JBrowse link
G DEAF1 DEAF1 transcription factor ISO (PMID:18826651)
(MGI:3822223|PMID:18826651)
UniProtKB
UniProt
PMID:18826651 MGI:3822223 NCBI chr11:652,337...709,854 JBrowse link
G GPX1 glutathione peroxidase 1 ISO (PMID:16945136) BHF-UCL PMID:16945136 NCBI chr 3:49,280,038...49,281,455
Ensembl chr 3:50,360,947...50,361,826
JBrowse link
G HOXA5 homeobox A5 ISO (MGI:3624927|PMID:16607641) MGI PMID:16607641 MGI:3624927 NCBI chr 7:27,786,040...27,789,339
Ensembl chr 7:27,385,175...27,388,990
JBrowse link
G PYGO2 pygopus family PHD finger 2 ISO (MGI:4821247|PMID:19487454) MGI PMID:19487454 MGI:4821247 NCBI chr 1:130,305,547...130,310,270
Ensembl chr 1:133,912,411...133,920,308
JBrowse link
tertiary branching involved in mammary gland duct morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AR androgen receptor ISO (MGI:2683859|PMID:14676301) MGI PMID:14676301 MGI:2683859 NCBI chr  X:56,722,828...56,909,004
Ensembl chr  X:66,791,081...66,969,357
JBrowse link
G PGR progesterone receptor ISO (MGI:1354852|PMID:10733525) MGI PMID:10733525 MGI:1354852 NCBI chr11:95,997,677...96,098,866 JBrowse link
G WNT4 Wnt family member 4 ISO (MGI:1354852|PMID:10733525) MGI PMID:10733525 MGI:1354852 NCBI chr 1:21,310,228...21,335,985
Ensembl chr 1:22,255,056...22,268,801
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12567
    developmental process 5840
      anatomical structure development 5453
        tissue development 1920
          epithelium development 1176
            mammary gland epithelium development 78
              mammary gland duct morphogenesis + 40
              mammary gland epithelial cell differentiation + 17
              mammary gland epithelial cell proliferation + 31
Path 2
Term Annotations click to browse term
  biological_process 12567
    developmental process 5840
      anatomical structure development 5453
        multicellular organism development 4985
          system development 4689
            animal organ development 3618
              gland development 593
                mammary gland development 171
                  mammary gland epithelium development 78
                    mammary gland duct morphogenesis + 40
                    mammary gland epithelial cell differentiation + 17
                    mammary gland epithelial cell proliferation + 31
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.