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ONTOLOGY REPORT - ANNOTATIONS


Term:canonical Wnt signaling pathway involved in ureteric bud branching
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Accession:GO:0061291 term browser browse the term
Definition:The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the branching of the ureteric bud. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
Synonyms:exact_synonym: canonical Wnt receptor signaling pathway involved in ureteric bud branching;   canonical Wnt receptor signalling pathway involved in ureteric bud branching


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Path 1
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  biological_process 12529
    developmental process 5818
      anatomical structure morphogenesis 2572
        tube morphogenesis 870
          branching morphogenesis of an epithelial tube 187
            branching involved in ureteric bud morphogenesis 66
              canonical Wnt signaling pathway involved in ureteric bud branching 0
Path 2
Term Annotations click to browse term
  biological_process 12529
    developmental process 5818
      anatomical structure development 5431
        multicellular organism development 4970
          system development 4675
            urogenital system development 415
              renal system development 369
                kidney development 355
                  nephron development 164
                    nephron epithelium development 122
                      nephron tubule development 104
                        nephron tubule morphogenesis 84
                          mesonephric tubule morphogenesis 75
                            ureteric bud morphogenesis 74
                              branching involved in ureteric bud morphogenesis 66
                                canonical Wnt signaling pathway involved in ureteric bud branching 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.