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ONTOLOGY REPORT - ANNOTATIONS


Term:canonical Wnt signaling pathway involved in ureteric bud branching
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Accession:GO:0061291 term browser browse the term
Definition:The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the branching of the ureteric bud. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
Synonyms:exact_synonym: canonical Wnt receptor signaling pathway involved in ureteric bud branching;   canonical Wnt receptor signalling pathway involved in ureteric bud branching


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Path 1
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  biological_process 11862
    developmental process 5599
      anatomical structure morphogenesis 2493
        tube morphogenesis 838
          branching morphogenesis of an epithelial tube 183
            branching involved in ureteric bud morphogenesis 65
              canonical Wnt signaling pathway involved in ureteric bud branching 0
Path 2
Term Annotations click to browse term
  biological_process 11862
    developmental process 5599
      anatomical structure development 5237
        multicellular organism development 4801
          system development 4520
            urogenital system development 401
              renal system development 354
                kidney development 340
                  nephron development 158
                    nephron epithelium development 118
                      nephron tubule development 102
                        nephron tubule morphogenesis 83
                          mesonephric tubule morphogenesis 74
                            ureteric bud morphogenesis 73
                              branching involved in ureteric bud morphogenesis 65
                                canonical Wnt signaling pathway involved in ureteric bud branching 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.