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ONTOLOGY REPORT - ANNOTATIONS


Term:canonical Wnt signaling pathway involved in ureteric bud branching
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Accession:GO:0061291 term browser browse the term
Definition:The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the branching of the ureteric bud. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
Synonyms:exact_synonym: canonical Wnt receptor signaling pathway involved in ureteric bud branching;   canonical Wnt receptor signalling pathway involved in ureteric bud branching


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Path 1
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  biological_process 11968
    developmental process 5628
      anatomical structure morphogenesis 2512
        tube morphogenesis 849
          branching morphogenesis of an epithelial tube 186
            branching involved in ureteric bud morphogenesis 64
              canonical Wnt signaling pathway involved in ureteric bud branching 0
Path 2
Term Annotations click to browse term
  biological_process 11968
    developmental process 5628
      anatomical structure development 5266
        multicellular organism development 4832
          system development 4554
            urogenital system development 403
              renal system development 358
                kidney development 344
                  nephron development 159
                    nephron epithelium development 118
                      nephron tubule development 101
                        nephron tubule morphogenesis 82
                          mesonephric tubule morphogenesis 73
                            ureteric bud morphogenesis 72
                              branching involved in ureteric bud morphogenesis 64
                                canonical Wnt signaling pathway involved in ureteric bud branching 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.