ONTOLOGY REPORT - ANNOTATIONS


Term:cell proliferation involved in heart morphogenesis
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Accession:GO:0061323 term browser browse the term
Definition:The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the heart.


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canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:1624291
RGD:1600115
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291
cell proliferation involved in endocardial cushion morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tgfbr2 transforming growth factor, beta receptor 2 JBrowse link 8 124,310,288 124,399,345 RGD:1624291
cell proliferation involved in outflow tract morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hand2 heart and neural crest derivatives expressed 2 JBrowse link 16 36,371,489 36,373,551 RGD:1624291
G Pitx2 paired-like homeodomain 2 JBrowse link 2 233,602,732 233,621,059 RGD:1624291
RGD:1600115
negative regulation of cell proliferation involved in heart morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1624291
RGD:1600115
negative regulation of cell proliferation involved in heart valve morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmpr2 bone morphogenetic protein receptor type 2 JBrowse link 9 66,568,074 66,683,019 RGD:1624291
RGD:1600115
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1600115
RGD:1624291
Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
RGD:1600115
positive regulation of cardioblast proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase JBrowse link 20 8,165,423 8,169,557 RGD:1624291
RGD:1600115
positive regulation of cell proliferation involved in heart morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp10 bone morphogenetic protein 10 JBrowse link 4 119,224,906 119,230,534 RGD:1624291
RGD:1600115
G Naca nascent polypeptide associated complex subunit alpha JBrowse link 7 2,458,283 2,470,674 RGD:1624291
G Rbpj recombination signal binding protein for immunoglobulin kappa J region JBrowse link 14 59,657,738 59,865,427 RGD:1624291
G Sox9 SRY box 9 JBrowse link 10 101,288,528 101,294,030 RGD:1624291
RGD:1600115
positive regulation of cell proliferation involved in heart valve morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Smad4 SMAD family member 4 JBrowse link 18 69,626,682 69,657,373 RGD:1624291
RGD:1600115
positive regulation of cell proliferation involved in outflow tract morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1624291
RGD:1600115
positive regulation of secondary heart field cardioblast proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Eya1 EYA transcriptional coactivator and phosphatase 1 JBrowse link 5 4,275,728 4,495,525 RGD:1624291
G Gng5 G protein subunit gamma 5 JBrowse link 2 252,359,976 252,368,473 RGD:1624291
G Six1 SIX homeobox 1 JBrowse link 6 95,929,060 95,934,296 RGD:1624291
RGD:1600115
G Tbx1 T-box 1 JBrowse link 11 86,552,022 86,561,647 RGD:1624291
G Tbx5 T-box 5 JBrowse link 12 42,059,688 42,148,226 RGD:1624291
RGD:1600115
regulation of cardioblast proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:2325311
regulation of cell proliferation involved in heart morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Eng endoglin JBrowse link 3 11,679,530 11,717,486 RGD:1624291
regulation of secondary heart field cardioblast proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:1624291
RGD:1600115
G Hand2 heart and neural crest derivatives expressed 2 JBrowse link 16 36,371,489 36,373,551 RGD:1624291
G Hes1 hes family bHLH transcription factor 1 JBrowse link 11 74,312,837 74,315,249 RGD:1624291
RGD:1600115
G Isl1 ISL LIM homeobox 1 JBrowse link 2 48,488,911 48,501,217 RGD:1624291
RGD:1600115
smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mks1 MKS transition zone complex subunit 1 JBrowse link 10 75,149,814 75,160,481 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17896
    cell population proliferation 2082
      cell proliferation involved in heart morphogenesis 23
        cardioblast proliferation + 12
        cell proliferation involved in atrial ventricular junction remodeling 0
        cell proliferation involved in endocardial cushion morphogenesis 1
        cell proliferation involved in heart valve morphogenesis + 3
        cell proliferation involved in outflow tract morphogenesis + 5
        fibroblast proliferation involved in heart morphogenesis 0
        negative regulation of cell proliferation involved in heart morphogenesis + 3
        positive regulation of cell proliferation involved in heart morphogenesis + 7
        regulation of cell proliferation involved in heart morphogenesis + 21
Path 2
Term Annotations click to browse term
  biological_process 17896
    developmental process 6323
      anatomical structure development 5930
        multicellular organism development 5425
          system development 5004
            circulatory system development 1174
              heart development 672
                heart morphogenesis 276
                  cell proliferation involved in heart morphogenesis 23
                    cardioblast proliferation + 12
                    cell proliferation involved in atrial ventricular junction remodeling 0
                    cell proliferation involved in endocardial cushion morphogenesis 1
                    cell proliferation involved in heart valve morphogenesis + 3
                    cell proliferation involved in outflow tract morphogenesis + 5
                    fibroblast proliferation involved in heart morphogenesis 0
                    negative regulation of cell proliferation involved in heart morphogenesis + 3
                    positive regulation of cell proliferation involved in heart morphogenesis + 7
                    regulation of cell proliferation involved in heart morphogenesis + 21
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.