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ONTOLOGY REPORT - ANNOTATIONS


Term:planar cell polarity pathway involved in heart morphogenesis
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Accession:GO:0061346 term browser browse the term
Definition:The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the heart.


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planar cell polarity pathway involved in heart morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Vangl2 VANGL planar cell polarity protein 2 JBrowse link 13 90,379,203 90,405,627 RGD:1624291
RGD:1600115
negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291
negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291
negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291
negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
planar cell polarity pathway involved in cardiac right atrium morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
planar cell polarity pathway involved in outflow tract morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
planar cell polarity pathway involved in pericardium morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
planar cell polarity pathway involved in ventricular septum morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17967
    developmental process 6388
      anatomical structure morphogenesis 2755
        animal organ morphogenesis 1111
          heart morphogenesis 280
            planar cell polarity pathway involved in heart morphogenesis 3
              negative regulation of planar cell polarity pathway involved in heart morphogenesis + 1
              planar cell polarity pathway involved in cardiac muscle tissue morphogenesis + 2
              planar cell polarity pathway involved in cardiac right atrium morphogenesis + 2
              planar cell polarity pathway involved in outflow tract morphogenesis + 2
              planar cell polarity pathway involved in pericardium morphogenesis + 2
              planar cell polarity pathway involved in ventricular septum morphogenesis + 2
              regulation of planar cell polarity pathway involved in heart morphogenesis + 1
Path 2
Term Annotations click to browse term
  biological_process 17967
    biological regulation 12663
      regulation of biological process 12001
        regulation of cellular process 11338
          signal transduction 6529
            cell surface receptor signaling pathway 2510
              cell surface receptor signaling pathway involved in cell-cell signaling 543
                Wnt signaling pathway 426
                  non-canonical Wnt signaling pathway 57
                    Wnt signaling pathway, planar cell polarity pathway 37
                      planar cell polarity pathway involved in heart morphogenesis 3
                        negative regulation of planar cell polarity pathway involved in heart morphogenesis + 1
                        planar cell polarity pathway involved in cardiac muscle tissue morphogenesis + 2
                        planar cell polarity pathway involved in cardiac right atrium morphogenesis + 2
                        planar cell polarity pathway involved in outflow tract morphogenesis + 2
                        planar cell polarity pathway involved in pericardium morphogenesis + 2
                        planar cell polarity pathway involved in ventricular septum morphogenesis + 2
                        regulation of planar cell polarity pathway involved in heart morphogenesis + 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.