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ONTOLOGY REPORT - ANNOTATIONS


Term:planar cell polarity pathway involved in ventricular septum morphogenesis
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Accession:GO:0061348 term browser browse the term
Definition:The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the ventricular septum.


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planar cell polarity pathway involved in ventricular septum morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18179
    developmental process 6551
      anatomical structure morphogenesis 2778
        cardiac septum morphogenesis 86
          ventricular septum morphogenesis 51
            planar cell polarity pathway involved in ventricular septum morphogenesis 2
              negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis 1
              regulation of planar cell polarity pathway involved in ventricular septum morphogenesis + 1
Path 2
Term Annotations click to browse term
  biological_process 18179
    developmental process 6551
      anatomical structure development 6031
        multicellular organism development 5511
          system development 5062
            animal organ development 3866
              heart development 681
                cardiac chamber development 196
                  cardiac ventricle development 147
                    ventricular septum development 86
                      ventricular septum morphogenesis 51
                        planar cell polarity pathway involved in ventricular septum morphogenesis 2
                          negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis 1
                          regulation of planar cell polarity pathway involved in ventricular septum morphogenesis + 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.