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ONTOLOGY REPORT - ANNOTATIONS


Term:planar cell polarity pathway involved in cardiac muscle tissue morphogenesis
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Accession:GO:0061350 term browser browse the term
Definition:The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the cardiac muscle tissue.


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planar cell polarity pathway involved in cardiac muscle tissue morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18179
    developmental process 6551
      anatomical structure morphogenesis 2778
        tissue morphogenesis 693
          muscle tissue morphogenesis 83
            cardiac muscle tissue morphogenesis 69
              planar cell polarity pathway involved in cardiac muscle tissue morphogenesis 2
                negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis 1
                regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis + 1
Path 2
Term Annotations click to browse term
  biological_process 18179
    biological regulation 12814
      regulation of biological process 12149
        regulation of cellular process 11482
          signal transduction 6611
            cell surface receptor signaling pathway 2540
              cell surface receptor signaling pathway involved in cell-cell signaling 551
                Wnt signaling pathway 431
                  non-canonical Wnt signaling pathway 58
                    Wnt signaling pathway, planar cell polarity pathway 37
                      planar cell polarity pathway involved in heart morphogenesis 3
                        planar cell polarity pathway involved in cardiac muscle tissue morphogenesis 2
                          negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis 1
                          regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis + 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.