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ONTOLOGY REPORT - ANNOTATIONS


Term:GATOR2 complex
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Accession:GO:0061700 term browser browse the term
Definition:A multiprotein subcomplex of GATOR that regulates mTOR signaling by interacting with the Rag GTPases. In humans this complex consists of Mios, WDR24, WDR59, Seh1L, Sec13.


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GATOR2 complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Castor1 cytosolic arginine sensor for mTORC1 subunit 1 JBrowse link 14 84,447,552 84,457,396 RGD:1624291
RGD:13792537
RGD:1600115
G Castor2 cytosolic arginine sensor for mTORC1 subunit 2 JBrowse link 12 25,595,800 25,638,806 RGD:1624291
RGD:13792537
G Mios meiosis regulator for oocyte development JBrowse link 4 34,238,370 34,264,015 RGD:1624291
G Sec13 SEC13 homolog, nuclear pore and COPII coat complex component JBrowse link 4 145,686,186 145,699,577 RGD:1624291
G Seh1l SEH1-like nucleoporin JBrowse link 18 63,545,150 63,568,101 RGD:1624291
G Sesn1 sestrin 1 JBrowse link 20 46,667,116 46,758,306 RGD:1624291
RGD:13792537
G Sesn2 sestrin 2 JBrowse link 5 150,684,891 150,703,846 RGD:1624291
RGD:13792537
G Sesn3 sestrin 3 JBrowse link 8 12,823,060 12,878,749 RGD:1624291
RGD:13792537
G Szt2 SZT2 subunit of KICSTOR complex JBrowse link 5 137,192,120 137,238,384 RGD:1624291
G Wdr24 WD repeat domain 24 JBrowse link 10 15,191,078 15,195,860 RGD:1624291
G Wdr59 WD repeat domain 59 JBrowse link 19 43,651,686 43,714,391 RGD:1624291

Term paths to the root
Path 1
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  cellular_component 19951
    protein-containing complex 5828
      GATOR2 complex 11
Path 2
Term Annotations click to browse term
  cellular_component 19951
    protein-containing complex 5828
      Seh1-associated complex 16
        GATOR2 complex 11
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.