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ONTOLOGY REPORT - ANNOTATIONS


Term:leukotriene signaling pathway
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Accession:GO:0061737 term browser browse the term
Definition:A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-leukotriene interaction and ends with regulation of a downstream cellular process, e.g. transcription.


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leukotriene signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cysltr1 cysteinyl leukotriene receptor 1 JBrowse link X 77,671,028 77,700,491 RGD:1600115
G Cysltr2 cysteinyl leukotriene receptor 2 JBrowse link 15 54,903,290 54,941,742 RGD:1600115
G Ltb4r leukotriene B4 receptor JBrowse link 15 34,449,299 34,453,352 RGD:1600115
G Ltb4r2 leukotriene B4 receptor 2 JBrowse link 15 34,446,478 34,448,220 RGD:1600115
G Rgs1 regulator of G-protein signaling 1 JBrowse link 13 61,066,196 61,070,772 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18166
    signaling 7108
      signal transduction 6597
        G protein-coupled receptor signaling pathway 2395
          leukotriene signaling pathway 5
Path 2
Term Annotations click to browse term
  biological_process 18166
    biological regulation 12793
      regulation of biological process 12128
        regulation of cellular process 11458
          signal transduction 6597
            G protein-coupled receptor signaling pathway 2395
              leukotriene signaling pathway 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.