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ONTOLOGY REPORT - ANNOTATIONS


Term:ubiquitin-dependent endocytosis
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Accession:GO:0070086 term browser browse the term
Definition:Endocytosis of a protein that requires the substrate to be modified by ubiquitination. Several plasma membrane proteins, including cell surface permeases and some receptors, are targeted for internalization by endocytosis, and are thereafter delivered to the vacuole or lysosome, where they are degraded.
Synonyms:exact_synonym: ubiquitin-mediated endocytosis


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ubiquitin-dependent endocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il10ra interleukin 10 receptor subunit alpha JBrowse link 8 49,558,062 49,573,891 RGD:1624291
G Lrsam1 leucine rich repeat and sterile alpha motif containing 1 JBrowse link 3 11,970,401 12,009,463 RGD:1624291
G Neurl1b neuralized E3 ubiquitin protein ligase 1B JBrowse link 10 17,048,251 17,075,139 RGD:1624291
RGD:13792537
positive regulation of ubiquitin-dependent endocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tsg101 tumor susceptibility 101 JBrowse link 1 102,941,151 102,971,017 RGD:1624291
G Vps28 VPS28 subunit of ESCRT-I JBrowse link 7 117,684,339 117,688,187 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    cellular process 18617
      vesicle-mediated transport 1651
        endocytosis 670
          ubiquitin-dependent endocytosis 5
            negative regulation of ubiquitin-dependent endocytosis 0
            positive regulation of ubiquitin-dependent endocytosis 2
            regulation of ubiquitin-dependent endocytosis + 2
Path 2
Term Annotations click to browse term
  biological_process 19858
    localization 6457
      establishment of localization 4907
        transport 4764
          nitrogen compound transport 2188
            amide transport 1855
              peptide transport 1821
                protein transport 1763
                  ubiquitin-dependent endocytosis 5
                    negative regulation of ubiquitin-dependent endocytosis 0
                    positive regulation of ubiquitin-dependent endocytosis 2
                    regulation of ubiquitin-dependent endocytosis + 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.