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ONTOLOGY REPORT - ANNOTATIONS


Term:ciliary neurotrophic factor-mediated signaling pathway
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Accession:GO:0070120 term browser browse the term
Definition:A series of molecular signals initiated by the binding of a ciliary neurotrophic factor (CNTF) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: CNTF-mediated signaling pathway;   ciliary neurotrophic factor-mediated signalling pathway


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ciliary neurotrophic factor-mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cntf ciliary neurotrophic factor ISO
IBA
IEA
(PMID:12643274)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:12643274, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 1:229,599,009...229,601,032
Ensembl chr 1:229,599,009...229,601,032
JBrowse link
G Cntfr ciliary neurotrophic factor receptor ISO
IEA
IBA
(PMID:12643274)
MGI:MGI:88439 (MGI:MGI:76882|PMID:7585948)
GO_REF:0000107
PMID:21873635
RGD
Ensembl
PMID:7585948, PMID:12643274, PMID:21873635 GO_REF:0000107, MGI:MGI:76882, RGD:13792537 NCBI chr 5:58,041,114...58,078,687
Ensembl chr 5:58,041,146...58,078,545
JBrowse link
G Il6r interleukin 6 receptor ISO (PMID:12643274) RGD PMID:12643274 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628
JBrowse link
G Il6st interleukin 6 signal transducer ISO
IEA
(PMID:12643274)
GO_REF:0000107
RGD
Ensembl
PMID:12643274 GO_REF:0000107 NCBI chr 2:44,279,199...44,319,427
Ensembl chr 2:44,289,393...44,314,944
JBrowse link
G Lifr LIF receptor subunit alpha ISO
IEA
(PMID:12643274)
GO_REF:0000107
RGD
Ensembl
PMID:12643274 GO_REF:0000107 NCBI chr 2:56,424,910...56,489,346
Ensembl chr 2:56,426,367...56,489,415
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    signaling 7580
      signal transduction 7011
        cell surface receptor signaling pathway 2761
          cytokine-mediated signaling pathway 406
            ciliary neurotrophic factor-mediated signaling pathway 5
Path 2
Term Annotations click to browse term
  biological_process 20028
    response to stimulus 10583
      response to chemical 6342
        response to organic substance 3865
          cellular response to organic substance 2845
            cellular response to cytokine stimulus 998
              cytokine-mediated signaling pathway 406
                ciliary neurotrophic factor-mediated signaling pathway 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.