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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of biomineral tissue development
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Accession:GO:0070167 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.


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negative regulation of biomineral tissue development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gas6 growth arrest specific 6 JBrowse link 16 81,213,364 81,243,824 RGD:1624291
RGD:1600115
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 JBrowse link 2 95,320,147 95,322,701 RGD:1624291
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 JBrowse link 1 29,191,170 29,201,257 RGD:1624291
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:1600115
RGD:1624291
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
G Rock1 Rho-associated coiled-coil containing protein kinase 1 JBrowse link 18 1,273,490 1,390,790 RGD:1624291
G Rock2 Rho-associated coiled-coil containing protein kinase 2 JBrowse link 6 42,180,864 42,289,910 RGD:1624291
G Sox9 SRY-box transcription factor 9 JBrowse link 10 101,288,528 101,294,030 RGD:1624291
RGD:1600115
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
negative regulation of bone mineralization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ahsg alpha-2-HS-glycoprotein JBrowse link 11 81,711,269 81,717,594 RGD:1626074
RGD:1600115
RGD:1624291
G Bcor BCL6 co-repressor JBrowse link X 11,570,155 11,692,022 RGD:1624291
G Ccl3 C-C motif chemokine ligand 3 JBrowse link 10 70,869,516 70,871,066 RGD:1624291
G Ccr1 C-C motif chemokine receptor 1 JBrowse link 8 132,996,646 133,002,201 RGD:1624291
G Ecm1 extracellular matrix protein 1 JBrowse link 2 197,855,468 197,860,973 RGD:1624291
RGD:1600115
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 JBrowse link 1 21,748,201 21,813,205 RGD:1600115
RGD:1624291
G Fgf23 fibroblast growth factor 23 JBrowse link 4 159,622,404 159,630,082 RGD:1624291
G Gata1 GATA binding protein 1 JBrowse link X 15,273,937 15,281,759 RGD:1624291
G Grem1 gremlin 1, DAN family BMP antagonist JBrowse link 3 105,203,309 105,214,989 RGD:1624291
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:1624291
RGD:1600115
G Ltbp3 latent transforming growth factor beta binding protein 3 JBrowse link 1 221,099,155 221,116,096 RGD:1624291
G Mepe matrix extracellular phosphoglycoprotein JBrowse link 14 6,782,011 6,793,561 RGD:1624291
G Nfe2 nuclear factor, erythroid 2 JBrowse link 7 144,872,739 144,880,092 RGD:1624291
G Ptk2b protein tyrosine kinase 2 beta JBrowse link 15 42,827,306 42,947,796 RGD:1624291
RGD:1600115
G Sox9 SRY-box transcription factor 9 JBrowse link 10 101,288,528 101,294,030 RGD:1624291
G Srgn serglycin JBrowse link 20 32,120,317 32,158,071 RGD:1624291
RGD:13792537
RGD:1600115
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 JBrowse link 1 101,293,300 101,323,484 RGD:10003033
negative regulation of bone mineralization involved in bone maturation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Grem1 gremlin 1, DAN family BMP antagonist JBrowse link 3 105,203,309 105,214,989 RGD:1624291
G Pth parathyroid hormone JBrowse link 1 178,215,829 178,218,761 RGD:12793028
G Rflna refilin A JBrowse link 12 37,038,732 37,047,628 RGD:1624291
RGD:13792537
G Rflnb refilin B JBrowse link 10 64,196,103 64,202,380 RGD:1624291
RGD:13792537
negative regulation of tooth mineralization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aspn asporin JBrowse link 17 14,655,958 14,681,355 RGD:1624291
G Bcor BCL6 co-repressor JBrowse link X 11,570,155 11,692,022 RGD:1624291
positive regulation of biomineral tissue development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Amtn amelotin JBrowse link 14 21,282,488 21,301,966 RGD:1624291
G Atf4 activating transcription factor 4 JBrowse link 7 121,480,723 121,482,781 RGD:1624291
G Cebpb CCAAT/enhancer binding protein beta JBrowse link 3 164,424,502 164,425,933 RGD:1624291
G Fbxo5 F-box protein 5 JBrowse link 1 42,461,277 42,467,646 RGD:1624291
G Odaph odontogenesis associated phosphoprotein JBrowse link 14 17,575,295 17,583,214 RGD:1624291
RGD:1600115
positive regulation of bone mineralization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acvr1 activin A receptor type 1 JBrowse link 3 44,432,476 44,539,680 RGD:1624291
RGD:1600115
G Acvr2a activin A receptor type 2A JBrowse link 3 32,947,901 33,034,598 RGD:1624291
RGD:1600115
G Acvr2b activin A receptor type 2B JBrowse link 8 128,087,308 128,126,776 RGD:1624291
RGD:1600115
G Adgrv1 adhesion G protein-coupled receptor V1 JBrowse link 2 8,926,843 9,504,455 RGD:1624291
G Adrb2 adrenoceptor beta 2 JBrowse link 18 57,513,792 57,515,834 RGD:1624291
RGD:1600115
G Alox5 arachidonate 5-lipoxygenase JBrowse link 4 148,398,004 148,446,308 RGD:1600115
RGD:1624291
G Ano6 anoctamin 6 JBrowse link 7 137,142,063 137,335,208 RGD:1624291
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 JBrowse link 7 41,114,606 41,223,138 RGD:1600115
RGD:1624291
G Atraid all-trans retinoic acid-induced differentiation factor JBrowse link 6 26,680,628 26,685,185 RGD:1624291
G Bmp2 bone morphogenetic protein 2 JBrowse link 3 126,335,963 126,346,771 RGD:1600115
RGD:1624291
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:9068399
RGD:1624291
RGD:1600115
G Bmp6 bone morphogenetic protein 6 JBrowse link 17 26,955,142 27,112,820 RGD:1624291
G Bmp7 bone morphogenetic protein 7 JBrowse link 3 170,879,972 170,955,820 RGD:1624291
G Bmpr1a bone morphogenetic protein receptor type 1A JBrowse link 16 10,758,278 10,852,170 RGD:1624291
G Bmpr1b bone morphogenetic protein receptor type 1B JBrowse link 2 247,392,195 247,662,026 RGD:1624291
G Bmpr2 bone morphogenetic protein receptor type 2 JBrowse link 9 66,568,074 66,683,019 RGD:1624291
G Ccn1 cellular communication network factor 1 JBrowse link 2 251,529,354 251,532,312 RGD:1600115
RGD:1624291
G Cd276 Cd276 molecule JBrowse link 8 63,312,060 63,350,411 RGD:1624291
G Fam20c FAM20C, golgi associated secretory pathway kinase JBrowse link 12 17,913,771 17,972,733 RGD:1624291
G Fbn2 fibrillin 2 JBrowse link 18 53,068,495 53,272,254 RGD:1624291
G Fgfr3 fibroblast growth factor receptor 3 JBrowse link 14 82,272,322 82,287,739 RGD:1624291
G Fzd9 frizzled class receptor 9 JBrowse link 12 24,473,981 24,476,295 RGD:1624291
RGD:1600115
G Gpm6b glycoprotein m6b JBrowse link X 29,604,607 29,751,174 RGD:1600115
RGD:1624291
G Isg15 ISG15 ubiquitin-like modifier JBrowse link 5 173,624,862 173,629,124 RGD:1624291
G Kl Klotho JBrowse link 12 942,974 987,206 RGD:1600115
RGD:1624291
G Mef2c myocyte enhancer factor 2C JBrowse link 2 11,658,534 11,822,788 RGD:1600115
RGD:1624291
G Mia3 MIA SH3 domain ER export factor 3 JBrowse link 13 101,727,434 101,770,127 RGD:1624291
G Nell1 neural EGFL like 1 JBrowse link 1 105,348,577 106,218,970 RGD:1624291
RGD:1600115
G Osr1 odd-skipped related transcription factor 1 JBrowse link 6 35,314,431 35,321,458 RGD:1624291
G Osr2 odd-skipped related transciption factor 2 JBrowse link 7 74,047,820 74,055,096 RGD:1624291
G P2rx7 purinergic receptor P2X 7 JBrowse link 12 39,353,613 39,396,042 RGD:1624291
G Pkdcc protein kinase domain containing, cytoplasmic JBrowse link 6 6,427,657 6,436,974 RGD:1624291
G Pla2g4a phospholipase A2 group IVA JBrowse link 13 67,062,252 67,206,688 RGD:1642474
G Pth parathyroid hormone JBrowse link 1 178,215,829 178,218,761 RGD:7207452
RGD:1624291
RGD:7242906
G Ptn pleiotrophin JBrowse link 4 64,239,156 64,330,996 RGD:1600115
RGD:1624291
G Slc8a1 solute carrier family 8 member A1 JBrowse link 6 4,244,076 4,564,262 RGD:1624291
G Smad3 SMAD family member 3 JBrowse link 8 68,569,530 68,678,349 RGD:727387
G Tfap2a transcription factor AP-2 alpha JBrowse link 17 24,653,342 24,670,457 RGD:1624291
RGD:1600115
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
RGD:1600115
G Tgfb3 transforming growth factor, beta 3 JBrowse link 6 109,913,757 109,936,217 RGD:1624291
RGD:1600115
G Tmem119 transmembrane protein 119 JBrowse link 12 48,598,498 48,605,704 RGD:1624291
RGD:13792537
G Wnt10b Wnt family member 10B JBrowse link 7 140,448,284 140,466,159 RGD:1624291
G Wnt4 Wnt family member 4 JBrowse link 5 155,649,238 155,668,065 RGD:1624291
RGD:1600115
positive regulation of bone mineralization involved in bone maturation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Actn3 actinin alpha 3 JBrowse link 1 220,120,532 220,136,460 RGD:1624291
G Asxl2 ASXL transcriptional regulator 2 JBrowse link 6 27,835,346 27,919,285 RGD:1624291
positive regulation of enamel mineralization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Amtn amelotin JBrowse link 14 21,282,488 21,301,966 RGD:1624291
RGD:13792537
RGD:1600115
G Dspp dentin sialophosphoprotein JBrowse link 14 6,926,972 6,933,079 RGD:1624291
G Enam enamelin JBrowse link 14 21,194,635 21,219,529 RGD:1624291
RGD:13792537
G Odaph odontogenesis associated phosphoprotein JBrowse link 14 17,575,295 17,583,214 RGD:1624291
RGD:13792537
RGD:1600115
positive regulation of tooth mineralization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tfap2a transcription factor AP-2 alpha JBrowse link 17 24,653,342 24,670,457 RGD:1624291
RGD:1600115
G Wnt6 Wnt family member 6 JBrowse link 9 82,033,543 82,047,172 RGD:1624291
regulation of bone mineralization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ankh ANKH inorganic pyrophosphate transport regulator JBrowse link 2 80,131,563 80,256,948 RGD:634632
RGD:1624291
RGD:1600115
G Bglap bone gamma-carboxyglutamate protein JBrowse link 2 187,741,770 187,748,445 RGD:1600115
G Bmp2k BMP-2 inducible kinase JBrowse link 14 14,126,086 14,226,823 RGD:1624291
RGD:13792537
G Comp cartilage oligomeric matrix protein JBrowse link 16 20,798,437 20,807,070 RGD:1624291
RGD:1600115
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 JBrowse link 7 70,333,150 70,340,006 RGD:1624291
G Ddr2 discoidin domain receptor tyrosine kinase 2 JBrowse link 13 88,311,639 88,436,561 RGD:1624291
G Dmp1 dentin matrix acidic phosphoprotein 1 JBrowse link 14 6,889,851 6,923,961 RGD:728616
G Ecm1 extracellular matrix protein 1 JBrowse link 2 197,855,468 197,860,973 RGD:1624291
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 JBrowse link 1 21,748,201 21,813,205 RGD:13792537
G Fgf23 fibroblast growth factor 23 JBrowse link 4 159,622,404 159,630,082 RGD:1624291
G Gja1 gap junction protein, alpha 1 JBrowse link 20 37,876,650 37,889,097 RGD:1624291
G LOC103690116 osteomodulin JBrowse link 17 14,635,588 14,646,368 RGD:1600115
G Matn1 matrilin 1 JBrowse link 5 149,077,412 149,086,957 RGD:1624291
G Mgp matrix Gla protein JBrowse link 4 170,856,783 170,860,105 RGD:1600115
G Nbr1 NBR1, autophagy cargo receptor JBrowse link 10 89,455,202 89,483,791 RGD:1624291
RGD:1600115
G Omd osteomodulin JBrowse link 17 15,476,100 15,484,324 RGD:633418
RGD:1600115
G S1pr1 sphingosine-1-phosphate receptor 1 JBrowse link 2 218,654,406 218,658,761 RGD:1624291
RGD:1600115
G Sgms2 sphingomyelin synthase 2 JBrowse link 2 236,458,276 236,530,667 RGD:1600115
RGD:1624291
G Suv39h1 suppressor of variegation 3-9 homolog 1 JBrowse link X 146,532,002 146,533,538 RGD:1624291
G Twist1 twist family bHLH transcription factor 1 JBrowse link 6 53,401,241 53,403,235 RGD:1624291
G Txlng taxilin gamma JBrowse link X 33,599,643 33,648,525 RGD:1624291
G Zmpste24 zinc metallopeptidase STE24 JBrowse link 5 139,982,404 140,015,541 RGD:1624291
regulation of enamel mineralization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dicer1 dicer 1 ribonuclease III JBrowse link 6 128,388,084 128,453,234 RGD:1624291
G Dmp1 dentin matrix acidic phosphoprotein 1 JBrowse link 14 6,889,851 6,923,961 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19578
    biomineralization 170
      regulation of biomineralization 101
        regulation of biomineral tissue development 100
          negative regulation of biomineral tissue development + 29
          positive regulation of biomineral tissue development + 53
          regulation of bone mineralization + 83
          regulation of shell calcification + 0
          regulation of tooth mineralization + 10
Path 2
Term Annotations click to browse term
  biological_process 19578
    developmental process 6697
      anatomical structure development 6155
        multicellular organism development 5623
          system development 5157
            animal organ development 3939
              biomineral tissue development 169
                regulation of biomineral tissue development 100
                  negative regulation of biomineral tissue development + 29
                  positive regulation of biomineral tissue development + 53
                  regulation of bone mineralization + 83
                  regulation of shell calcification + 0
                  regulation of tooth mineralization + 10
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.