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ONTOLOGY REPORT - ANNOTATIONS


Term:T cell apoptotic process
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Accession:GO:0070231 term browser browse the term
Definition:Any apoptotic process in a T cell, a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.
Synonyms:exact_synonym: T lymphocyte apoptosis;   programmed cell death of T cells by apoptosis
 narrow_synonym: T cell apoptosis


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T cell apoptotic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl10 BCL10, immune signaling adaptor JBrowse link 2 251,805,392 251,814,957 RGD:1624291
RGD:1600115
G Faslg Fas ligand JBrowse link 13 79,696,811 79,717,581 RGD:1624291
RGD:1600115
G Kdelr1 KDEL endoplasmic reticulum protein retention receptor 1 JBrowse link 1 101,859,346 101,870,232 RGD:1624291
RGD:1600115
G Lmbr1l limb development membrane protein 1-like JBrowse link 7 140,585,512 140,600,797 RGD:1600115
RGD:1624291
G Ripk1 receptor interacting serine/threonine kinase 1 JBrowse link 17 31,537,580 31,569,904 RGD:1624291
RGD:1600115
activation-induced cell death of T cells term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:1624291
RGD:1600115
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 JBrowse link 10 11,059,701 11,085,186 RGD:1624291
RGD:1600115
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:1624291
G Il2ra interleukin 2 receptor subunit alpha JBrowse link 17 70,500,672 70,547,929 RGD:1624291
RGD:1600115
G Rps6 ribosomal protein S6 JBrowse link 5 105,197,821 105,200,681 RGD:1624291
G Siva1 SIVA1, apoptosis-inducing factor JBrowse link 6 137,209,999 137,214,379 RGD:1624291
negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arg2 arginase 2 JBrowse link 6 102,311,097 102,338,406 RGD:1600115
RGD:1624291
negative regulation of activation-induced cell death of T cells term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fadd Fas associated via death domain JBrowse link 1 217,746,176 217,748,581 RGD:1624291
RGD:1600115
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial JBrowse link 1 275,843,823 275,906,880 RGD:1624291
RGD:1600115
G Tnfrsf4 TNF receptor superfamily member 4 JBrowse link 5 173,447,784 173,450,474 RGD:1624291
G Tsc22d3 TSC22 domain family, member 3 JBrowse link X 111,884,285 111,944,693 RGD:1624291
negative regulation of T cell apoptotic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl5 C-C motif chemokine ligand 5 JBrowse link 10 70,739,764 70,744,303 RGD:1624291
RGD:1600115
G Cd27 CD27 molecule JBrowse link 4 157,744,881 157,751,609 RGD:1624291
RGD:1600115
G Dock8 dedicator of cytokinesis 8 JBrowse link 1 242,934,685 243,153,472 RGD:1624291
RGD:1600115
G Ido1 indoleamine 2,3-dioxygenase 1 JBrowse link 16 72,216,326 72,228,098 RGD:1624291
RGD:1600115
G Il7r interleukin 7 receptor RGD:1624291
RGD:1600115
G Pip prolactin induced protein JBrowse link 4 71,320,859 71,325,153 RGD:1624291
G Prkcq protein kinase C, theta JBrowse link 17 70,971,915 71,105,286 RGD:1600115
RGD:1624291
G Rag1 recombination activating 1 JBrowse link 3 91,206,394 91,217,491 RGD:1624291
G Serpinb9 serpin family B member 9 JBrowse link 17 32,648,846 32,673,047 RGD:1624291
RGD:1600115
G Slc46a2 solute carrier family 46, member 2 JBrowse link 5 77,165,463 77,174,177 RGD:1624291
RGD:1600115
negative regulation of thymocyte apoptotic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ada adenosine deaminase JBrowse link 3 160,115,840 160,139,947 RGD:1624291
RGD:1600115
G Blm BLM RecQ like helicase JBrowse link 1 142,246,773 142,332,616 RGD:1624291
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1624291
RGD:1600115
G Efna1 ephrin A1 JBrowse link 2 188,588,808 188,596,156 RGD:1624291
RGD:1600115
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:1624291
RGD:1600115
G Jak3 Janus kinase 3 JBrowse link 16 20,107,471 20,120,678 RGD:1624291
RGD:1600115
G Ptcra pre T-cell antigen receptor alpha JBrowse link 9 16,528,970 16,539,383 RGD:1624291
RGD:13792537
G Rag1 recombination activating 1 JBrowse link 3 91,206,394 91,217,491 RGD:1624291
RGD:1600115
G Rorc RAR-related orphan receptor C JBrowse link 2 195,612,471 195,636,797 RGD:1624291
G Vhl von Hippel-Lindau tumor suppressor JBrowse link 4 145,580,869 145,587,835 RGD:1624291
RGD:1600115
positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd274 CD274 molecule JBrowse link 1 247,519,890 247,539,659 RGD:1624291
RGD:1600115
positive regulation of activated T cell autonomous cell death term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lgals9 galectin 9 JBrowse link 10 64,737,022 64,760,195 RGD:1624291
positive regulation of activation-induced cell death of T cells term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ceacam1 CEA cell adhesion molecule 1 JBrowse link 1 82,327,955 82,344,345 RGD:1624291
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:1624291
positive regulation of T cell apoptotic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl5 C-C motif chemokine ligand 5 JBrowse link 10 70,739,764 70,744,303 RGD:1624291
RGD:1600115
G Cd274 CD274 molecule JBrowse link 1 247,519,890 247,539,659 RGD:1624291
G Ido1 indoleamine 2,3-dioxygenase 1 JBrowse link 16 72,216,326 72,228,098 RGD:1600115
RGD:1624291
G Lgals5 lectin, galactose binding, soluble 5 JBrowse link 10 66,226,015 66,229,293 RGD:1624291
G Pdcd1 programmed cell death 1 JBrowse link 9 101,305,742 101,319,937 RGD:1624291
G Pdcd7 programmed cell death 7 JBrowse link 8 70,860,671 70,875,471 RGD:1624291
G Prelid1 PRELI domain containing 1 JBrowse link 17 9,834,245 9,837,285 RGD:1624291
RGD:1600115
G Siglec1 sialic acid binding Ig like lectin 1 JBrowse link 3 123,612,067 123,631,718 RGD:1624291
positive regulation of thymocyte apoptotic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adam8 ADAM metallopeptidase domain 8 JBrowse link 1 212,317,510 212,332,895 RGD:1624291
RGD:1600115
G Bbc3 Bcl-2 binding component 3 JBrowse link 1 78,261,491 78,267,802 RGD:1624291
G Nfkbid NFKB inhibitor delta JBrowse link 1 88,883,816 88,892,543 RGD:1624291
RGD:1600115
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:1624291
RGD:1600115
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
G Zc3h8 zinc finger CCCH type containing 8 JBrowse link 3 121,471,836 121,488,528 RGD:1624291
RGD:1600115
regulation of activated CD4-positive, alpha-beta T cell apoptotic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd274 CD274 molecule JBrowse link 1 247,519,890 247,539,659 RGD:1624291
regulation of activation-induced cell death of T cells term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ripk3 receptor-interacting serine-threonine kinase 3 JBrowse link 15 34,470,796 34,479,741 RGD:1624291
RGD:1600115
regulation of T cell apoptotic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd274 CD274 molecule JBrowse link 1 247,519,890 247,539,659 RGD:1624291
G Gimap8 GTPase, IMAP family member 8 JBrowse link 4 78,283,356 78,294,838 RGD:1624291
G Jak3 Janus kinase 3 JBrowse link 16 20,107,471 20,120,678 RGD:1624291
RGD:1600115
G Lgals3 galectin 3 JBrowse link 15 24,153,602 24,165,537 RGD:1624291
RGD:1600115
regulation of thymocyte apoptotic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Casp8 caspase 8 JBrowse link 9 65,614,142 65,662,624 RGD:1624291
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:1624291
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:1624291
G Vhl von Hippel-Lindau tumor suppressor JBrowse link 4 145,580,869 145,587,835 RGD:1624291
thymocyte apoptotic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bak1 BCL2-antagonist/killer 1 JBrowse link 20 5,609,620 5,618,899 RGD:1624291
RGD:1600115
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:1624291
RGD:1600115
G Bcl10 BCL10, immune signaling adaptor JBrowse link 2 251,805,392 251,814,957 RGD:1624291
G Bcl2l11 BCL2 like 11 JBrowse link 3 120,726,906 120,764,192 RGD:1624291
RGD:1600115
G Dffa DNA fragmentation factor subunit alpha JBrowse link 5 165,922,893 165,935,822 RGD:1624291
RGD:1600115
G Gli3 GLI family zinc finger 3 JBrowse link 17 52,294,942 52,569,036 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19312
    cellular process 17222
      cell death 2145
        programmed cell death 1967
          apoptotic process 1920
            leukocyte apoptotic process 138
              lymphocyte apoptotic process 99
                T cell apoptotic process 59
                  activated CD4-positive, alpha-beta T cell apoptotic process + 1
                  activated CD8-positive, alpha-beta T cell apoptotic process + 2
                  activated T cell autonomous cell death + 1
                  activation-induced cell death of T cells + 13
                  cytotoxic T cell apoptotic process 0
                  negative regulation of T cell apoptotic process + 24
                  positive regulation of T cell apoptotic process + 17
                  regulation of T cell apoptotic process + 43
                  regulatory T cell apoptotic process 0
                  thymocyte apoptotic process + 23
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.