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ONTOLOGY REPORT - ANNOTATIONS


Term:actin-mediated cell contraction
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Accession:GO:0070252 term browser browse the term
Definition:The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of all or part of the cell body.


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actin-mediated cell contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Actc1 actin, alpha, cardiac muscle 1 JBrowse link 3 105,507,403 105,512,939 RGD:1624291
G Emp2 epithelial membrane protein 2 JBrowse link 10 5,433,248 5,467,840 RGD:1600115
RGD:1624291
G Myh2 myosin heavy chain 2 JBrowse link 10 53,711,895 53,738,164 RGD:1624291
G Parva parvin, alpha JBrowse link 1 177,249,302 177,408,160 RGD:1600115
RGD:1624291
G Pdpn podoplanin JBrowse link 5 161,947,137 161,981,441 RGD:1624291
RGD:13792537
RGD:1600115
actin-myosin filament sliding term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Actc1 actin, alpha, cardiac muscle 1 JBrowse link 3 105,507,403 105,512,939 RGD:1624291
RGD:13792537
apical constriction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccdc88c coiled-coil domain containing 88C JBrowse link 6 124,905,811 125,028,011 RGD:1624291
G Epb41l5 erythrocyte membrane protein band 4.1 like 5 JBrowse link 13 35,622,472 35,673,449 RGD:1624291
G Frmd6 FERM domain containing 6 JBrowse link 6 93,281,382 93,358,888 RGD:1624291
RGD:1600115
G Pard3 par-3 family cell polarity regulator JBrowse link 19 60,017,746 60,580,628 RGD:1624291
G Rock1 Rho-associated coiled-coil containing protein kinase 1 JBrowse link 18 1,273,490 1,390,790 RGD:1624291
RGD:1600115
atrial cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ank2 ankyrin 2 JBrowse link 2 231,224,643 231,522,655 RGD:1624291
G Kcna5 potassium voltage-gated channel subfamily A member 5 JBrowse link 4 159,077,195 159,079,003 RGD:1624291
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 JBrowse link X 113,583,844 113,584,459 RGD:1624291
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 JBrowse link 1 216,293,087 216,630,339 RGD:1624291
G Nup155 nucleoporin 155 JBrowse link 2 57,206,665 57,258,242 RGD:1624291
RGD:1600115
G Scn3b sodium voltage-gated channel beta subunit 3 JBrowse link 8 44,136,413 44,159,011 RGD:1624291
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:1624291
RGD:1600115
cardiac muscle cell action potential involved in contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cacna1c calcium voltage-gated channel subunit alpha1 C JBrowse link 4 150,635,808 151,270,790 RGD:1624291
RGD:1600115
G Cacna1d calcium voltage-gated channel subunit alpha1 D JBrowse link 16 6,110,294 6,405,022 RGD:1600115
RGD:1624291
G Cacna1g calcium voltage-gated channel subunit alpha1 G JBrowse link 10 82,129,071 82,197,828 RGD:1600115
RGD:1624291
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 JBrowse link 4 15,706,974 16,130,848 RGD:1624291
RGD:1600115
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 JBrowse link 11 32,498,260 32,511,202 RGD:1624291
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 JBrowse link 11 32,434,786 32,447,264 RGD:1624291
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 JBrowse link 10 99,429,337 99,442,520 RGD:1624291
G Pkp2 plakophilin 2 JBrowse link 11 88,912,163 88,972,213 RGD:1624291
G Scn1a sodium voltage-gated channel alpha subunit 1 JBrowse link 3 52,388,811 52,533,365 RGD:1600115
RGD:1624291
G Scn1b sodium voltage-gated channel beta subunit 1 JBrowse link 1 89,550,738 89,560,469 RGD:1624291
RGD:13792537
G Scn2b sodium voltage-gated channel beta subunit 2 JBrowse link 8 49,419,003 49,431,110 RGD:1624291
G Scn3b sodium voltage-gated channel beta subunit 3 JBrowse link 8 44,136,413 44,159,011 RGD:1624291
RGD:13792537
G Scn4b sodium voltage-gated channel beta subunit 4 JBrowse link 8 49,441,106 49,456,279 RGD:1624291
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:1624291
RGD:1600115
cardiac muscle cell contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Camk2d calcium/calmodulin-dependent protein kinase II delta JBrowse link 2 230,900,907 231,132,207 RGD:8656014
G Sgcd sarcoglycan, delta JBrowse link 10 32,062,946 32,471,454 RGD:1624291
G Slc9a1 solute carrier family 9 member A1 JBrowse link 5 151,573,122 151,626,360 RGD:7349316
G Uty ubiquitously transcribed tetratricopeptide repeat containing, Y-linked JBrowse link Y 1,065,274 1,206,127 RGD:1624291
cytoplasmic actin-based contraction involved in cell motility term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Limch1 LIM and calponin homology domains 1 JBrowse link 14 42,760,363 43,072,976 RGD:1624291
G Shtn1 shootin 1 JBrowse link 1 280,129,228 280,233,873 RGD:10054078
G Vil1 villin 1 JBrowse link 9 81,689,802 81,717,623 RGD:1624291
membrane depolarization during atrial cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cacna1c calcium voltage-gated channel subunit alpha1 C JBrowse link 4 150,635,808 151,270,790 RGD:1624291
RGD:1600115
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 JBrowse link 17 81,673,862 82,019,219 RGD:1624291
RGD:1600115
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:1624291
RGD:1600115
membrane repolarization during atrial cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcna5 potassium voltage-gated channel subfamily A member 5 JBrowse link 4 159,077,195 159,079,003 RGD:1624291
G Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 JBrowse link 8 33,435,493 33,463,410 RGD:1624291
G Kcnn2 potassium calcium-activated channel subfamily N member 2 JBrowse link 18 39,331,894 39,479,574 RGD:1624291
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 JBrowse link 1 216,293,087 216,630,339 RGD:1600115
RGD:1624291
membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcnd3 potassium voltage-gated channel subfamily D member 3 JBrowse link 2 207,923,775 208,140,727 RGD:1600115
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 JBrowse link 11 32,498,260 32,511,202 RGD:1624291
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 JBrowse link 11 32,434,786 32,447,264 RGD:1624291
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 JBrowse link 1 165,189,934 165,196,949 RGD:1600115
G Kcne4 potassium voltage-gated channel subfamily E regulatory subunit 4 JBrowse link 9 84,688,873 84,693,066 RGD:1600115
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 JBrowse link X 113,583,844 113,584,459 RGD:1600115
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:1624291
RGD:1600115
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 JBrowse link 4 176,783,287 176,789,143 RGD:1624291
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 JBrowse link 1 216,293,087 216,630,339 RGD:1624291
RGD:13792537
RGD:1600115
muscle filament sliding term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Myh6 myosin heavy chain 6 JBrowse link 15 33,605,653 33,629,730 RGD:1624291
RGD:1600115
G Myh7 myosin heavy chain 7 JBrowse link 15 33,605,769 33,657,761 RGD:1600115
RGD:1624291
G Myh8 myosin heavy chain 8 JBrowse link 10 53,818,818 53,848,490 RGD:1624291
RGD:1600115
G Myl6l myosin, light polypeptide 6, alkali, smooth muscle and non-muscle-like RGD:8554813
G Tnnt2 troponin T2, cardiac type JBrowse link 13 52,662,974 52,680,992 RGD:1600115
RGD:1624291
G Tpm1 tropomyosin 1 JBrowse link 8 72,814,737 72,841,496 RGD:1556479
negative regulation of hepatic stellate cell contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nos1 nitric oxide synthase 1 JBrowse link 12 44,214,949 44,405,530 RGD:13824993
negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 JBrowse link 1 165,189,934 165,196,949 RGD:1624291
negative regulation of muscle filament sliding term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dbn1 drebrin 1 JBrowse link 17 9,679,511 9,693,878 RGD:10398727
negative regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bin1 bridging integrator 1 JBrowse link 18 25,163,575 25,222,139 RGD:1600115
RGD:1624291
positive regulation of atrial cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 JBrowse link 1 101,293,300 101,323,484 RGD:10003031
positive regulation of cardiac muscle cell contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 JBrowse link 1 197,855,912 197,875,038 RGD:1600115
G Cacna1h calcium voltage-gated channel subunit alpha1 H JBrowse link 10 14,730,932 14,789,201 RGD:7205486
positive regulation of hepatic stellate cell contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acta2 actin alpha 2, smooth muscle JBrowse link 1 252,537,614 252,550,394 RGD:12879446
positive regulation of myofibroblast contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ptger3 prostaglandin E receptor 3 JBrowse link 2 263,895,093 263,979,682 RGD:10045899
positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rnf207 ring finger protein 207 JBrowse link 5 169,486,253 169,500,451 RGD:1624291
regulation of atrial cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ank2 ankyrin 2 JBrowse link 2 231,224,643 231,522,655 RGD:1624291
G Gja5 gap junction protein, alpha 5 JBrowse link 2 199,162,745 199,184,942 RGD:1624291
G Ryr2 ryanodine receptor 2 JBrowse link 17 65,533,998 65,955,606 RGD:1624291
RGD:1600115
regulation of cardiac muscle cell action potential involved in regulation of contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akap9 A-kinase anchoring protein 9 JBrowse link 4 27,195,346 27,331,582 RGD:1624291
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 JBrowse link 12 39,553,903 39,603,326 RGD:10047146
G Camk2d calcium/calmodulin-dependent protein kinase II delta JBrowse link 2 230,900,907 231,132,207 RGD:10047271
G Cav3 caveolin 3 JBrowse link 4 144,382,945 144,398,919 RGD:1624291
G Fgf13 fibroblast growth factor 13 JBrowse link X 142,053,648 142,589,274 RGD:1624291
G Hcn4 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 JBrowse link 8 63,599,907 63,637,327 RGD:1600115
RGD:1624291
G Rangrf RAN guanine nucleotide release factor JBrowse link 10 55,559,049 55,560,420 RGD:1624291
regulation of cardiac muscle cell contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adora1 adenosine A1 receptor JBrowse link 13 51,042,111 51,076,913 RGD:2317914
G Adrb1 adrenoceptor beta 1 JBrowse link 1 277,537,585 277,538,985 RGD:6893639
RGD:2317914
G Akap6 A-kinase anchoring protein 6 JBrowse link 6 73,553,111 73,991,992 RGD:8553373
G Ank2 ankyrin 2 JBrowse link 2 231,224,643 231,522,655 RGD:1624291
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 JBrowse link 2 204,003,742 204,032,023 RGD:6903236
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 JBrowse link 13 90,651,682 90,676,629 RGD:6903343
G Casq2 calsequestrin 2 JBrowse link 2 204,512,361 204,568,643 RGD:2314601
G Fxyd1 FXYD domain-containing ion transport regulator 1 JBrowse link 1 89,484,197 89,488,279 RGD:9685468
G Gata4 GATA binding protein 4 JBrowse link 15 46,386,703 46,458,679 RGD:7207043
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 JBrowse link 10 99,429,337 99,442,520 RGD:7247430
G Pde4b phosphodiesterase 4B JBrowse link 5 121,759,236 122,136,814 RGD:1624291
G Pde4d phosphodiesterase 4D JBrowse link 2 40,219,999 41,468,551 RGD:7327160
RGD:13792537
RGD:1624291
RGD:1600115
G Pln phospholamban JBrowse link 20 34,633,157 34,642,904 RGD:1624291
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:1624291
RGD:1600115
G Sri sorcin JBrowse link 4 23,004,657 23,029,233 RGD:1624291
G Stc1 stanniocalcin 1 JBrowse link 15 50,891,137 50,901,791 RGD:1624291
G Sumo1 small ubiquitin-like modifier 1 JBrowse link 9 66,453,428 66,483,614 RGD:1624291
regulation of muscle filament sliding term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mylk2 myosin light chain kinase 2 JBrowse link 3 148,386,185 148,397,851 RGD:1624291
RGD:1600115
regulation of muscle filament sliding speed term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tnnc1 troponin C1, slow skeletal and cardiac type JBrowse link 16 7,292,207 7,295,238 RGD:1624291
G Tnnt2 troponin T2, cardiac type JBrowse link 13 52,662,974 52,680,992 RGD:8554013
regulation of myofibroblast contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdpn podoplanin JBrowse link 5 161,947,137 161,981,441 RGD:1624291
RGD:13792537
RGD:1600115
regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07034767.1 RGD:1600115
G AABR07044900.1 RGD:1600115
G Cacna1c calcium voltage-gated channel subunit alpha1 C JBrowse link 4 150,635,808 151,270,790 RGD:1600115
RGD:1624291
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:1624291
RGD:1600115
G Ctnna3 catenin alpha 3 JBrowse link 20 25,063,124 26,640,428 RGD:1624291
G Dlg1 discs large MAGUK scaffold protein 1 JBrowse link 11 72,164,566 72,378,895 RGD:1624291
G Dsc2 desmocollin 2 JBrowse link 18 11,826,705 11,858,801 RGD:1624291
G Dsg2 desmoglein 2 JBrowse link 18 15,579,322 15,637,720 RGD:1624291
G Dsp desmoplakin JBrowse link 17 27,286,811 27,334,453 RGD:1624291
G Jup junction plakoglobin JBrowse link 10 88,280,517 88,307,451 RGD:1624291
G Pkp2 plakophilin 2 JBrowse link 11 88,912,163 88,972,213 RGD:1624291
G Ryr2 ryanodine receptor 2 JBrowse link 17 65,533,998 65,955,606 RGD:1624291
RGD:1600115
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 JBrowse link 1 101,293,300 101,323,484 RGD:1600115
RGD:1624291
regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dlg1 discs large MAGUK scaffold protein 1 JBrowse link 11 72,164,566 72,378,895 RGD:1600115
RGD:1624291
substrate-dependent cell migration, cell contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc9 ATP binding cassette subfamily C member 9 JBrowse link 4 176,806,098 176,928,540 RGD:728123
ventricular cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07034767.1 RGD:1600115
G Ank2 ankyrin 2 JBrowse link 2 231,224,643 231,522,655 RGD:1624291
G Cav3 caveolin 3 JBrowse link 4 144,382,945 144,398,919 RGD:8553349
G Gja5 gap junction protein, alpha 5 JBrowse link 2 199,162,745 199,184,942 RGD:1624291
G Gpd1l glycerol-3-phosphate dehydrogenase 1-like JBrowse link 8 122,957,570 122,987,236 RGD:1624291
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 JBrowse link 11 32,498,260 32,511,202 RGD:1624291
RGD:13792537
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 JBrowse link 11 32,434,786 32,447,264 RGD:1624291
RGD:13792537
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 JBrowse link 1 165,189,934 165,196,949 RGD:13792537
G Kcne4 potassium voltage-gated channel subfamily E regulatory subunit 4 JBrowse link 9 84,688,873 84,693,066 RGD:13792537
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 JBrowse link X 113,583,844 113,584,459 RGD:1624291
RGD:13792537
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:1624291
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 JBrowse link 1 216,293,087 216,630,339 RGD:1624291
G Nedd4l NEDD4 like E3 ubiquitin protein ligase JBrowse link 18 60,392,376 60,719,720 RGD:8553349
G Pkp2 plakophilin 2 JBrowse link 11 88,912,163 88,972,213 RGD:1624291
G Ryr2 ryanodine receptor 2 JBrowse link 17 65,533,998 65,955,606 RGD:1624291
RGD:1600115
G Scn3b sodium voltage-gated channel beta subunit 3 JBrowse link 8 44,136,413 44,159,011 RGD:1624291
RGD:13792537
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:1624291
RGD:1600115
G Snta1 syntrophin, alpha 1 JBrowse link 3 149,874,023 149,905,980 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19676
    cellular process 18449
      actin filament-based process 824
        actin filament-based movement 127
          actin-mediated cell contraction 96
            actin-myosin filament sliding + 10
            apical constriction + 5
            cardiac muscle cell contraction + 70
            cytoplasmic actin-based contraction involved in cell motility + 4
            hepatic stellate cell contraction + 2
            myofibroblast contraction + 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.