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ONTOLOGY REPORT - ANNOTATIONS


Term:cornification
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Accession:GO:0070268 term browser browse the term
Definition:A type of programmed cell death that occurs in the epidermis, morphologically and biochemically distinct from apoptosis. It leads to the formation of corneocytes, i.e. dead keratinocytes containing an amalgam of specific proteins (e.g., keratin, loricrin, SPR and involucrin) and lipids (e.g., fatty acids and ceramides), which are necessary for the function of the cornified skin layer (mechanical resistance, elasticity, water repellence and structural stability).


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cornification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAPN1 calpain 1 TAS Reactome Reactome:R-HSA-6809371 NCBI chr11:65,181,373...65,212,006
Ensembl chr11:65,180,566...65,212,006
JBrowse link
G CAPNS1 calpain small subunit 1 TAS Reactome Reactome:R-HSA-6809371 NCBI chr19:36,140,066...36,150,353
Ensembl chr19:36,139,953...36,150,353
JBrowse link
G CASP14 caspase 14 TAS (PMID:18309324) UniProtKB PMID:18309324 Reactome:R-HSA-6809371 NCBI chr19:15,049,480...15,058,293
Ensembl chr19:15,049,480...15,058,293
JBrowse link
G CDSN corneodesmosin TAS Reactome Reactome:R-HSA-6809371 NCBI chr 6:31,115,087...31,120,446
Ensembl chr 6:31,115,087...31,120,446
JBrowse link
G CELA2A chymotrypsin like elastase 2A TAS Reactome Reactome:R-HSA-6809371 NCBI chr 1:15,456,732...15,472,091
Ensembl chr 1:15,456,728...15,472,091
JBrowse link
G CERS3 ceramide synthase 3 ISS UniProt GO_REF:0000024 NCBI chr15:100,400,395...100,544,982
Ensembl chr15:100,400,395...100,544,995
JBrowse link
G CSTA cystatin A TAS Reactome Reactome:R-HSA-6809371 NCBI chr 3:122,325,248...122,341,969
Ensembl chr 3:122,325,248...122,341,969
JBrowse link
G CYP26B1 cytochrome P450 family 26 subfamily B member 1 IEA Ensembl GO_REF:0000107 NCBI chr 2:72,129,238...72,147,862
Ensembl chr 2:72,129,238...72,148,038
JBrowse link
G DSC1 desmocollin 1 TAS Reactome Reactome:R-HSA-6809371 NCBI chr18:31,129,236...31,162,856
Ensembl chr18:31,129,236...31,162,856
JBrowse link
G DSC2 desmocollin 2 TAS Reactome Reactome:R-HSA-6809371 NCBI chr18:31,058,840...31,102,421
Ensembl chr18:31,058,840...31,102,522
JBrowse link
G DSC3 desmocollin 3 TAS Reactome Reactome:R-HSA-6809371 NCBI chr18:30,989,365...31,042,742
Ensembl chr18:30,989,365...31,042,815
JBrowse link
G DSG1 desmoglein 1 TAS Reactome Reactome:R-HSA-6809371 NCBI chr18:31,318,160...31,359,246
Ensembl chr18:31,318,160...31,359,246
JBrowse link
G DSG2 desmoglein 2 TAS Reactome Reactome:R-HSA-6809371 NCBI chr18:31,498,177...31,549,008
Ensembl chr18:31,498,177...31,549,008
JBrowse link
G DSG3 desmoglein 3 TAS Reactome Reactome:R-HSA-6809371 NCBI chr18:31,447,741...31,478,712
Ensembl chr18:31,447,741...31,478,702
JBrowse link
G DSG4 desmoglein 4 TAS Reactome Reactome:R-HSA-6809371 NCBI chr18:31,376,777...31,415,791
Ensembl chr18:31,376,777...31,414,912
JBrowse link
G DSP desmoplakin TAS Reactome Reactome:R-HSA-6809371 NCBI chr 6:7,541,671...7,586,714
Ensembl chr 6:7,541,617...7,586,714
JBrowse link
G EVPL envoplakin TAS Reactome Reactome:R-HSA-6809371 NCBI chr17:76,006,845...76,027,306
Ensembl chr17:76,004,502...76,027,452
Ensembl chr17:76,004,502...76,027,452
JBrowse link
G FLG filaggrin TAS Reactome Reactome:R-HSA-6809371 NCBI chr 1:152,302,165...152,325,239
Ensembl chr 1:152,302,165...152,325,239
Ensembl chr 1:152,302,165...152,325,239
JBrowse link
G FURIN furin, paired basic amino acid cleaving enzyme TAS Reactome Reactome:R-HSA-6809371 NCBI chr15:90,868,588...90,883,457
Ensembl chr15:90,868,588...90,883,458
JBrowse link
G IVL involucrin TAS Reactome Reactome:R-HSA-6809371 NCBI chr 1:152,908,545...152,911,886
Ensembl chr 1:152,908,546...152,911,886
JBrowse link
G JUP junction plakoglobin TAS Reactome Reactome:R-HSA-6809371 NCBI chr17:41,754,608...41,786,711
Ensembl chr17:41,754,604...41,786,931
JBrowse link
G KAZN kazrin, periplakin interacting protein TAS Reactome Reactome:R-HSA-6809371 NCBI chr 1:13,893,386...15,118,043
Ensembl chr 1:13,892,792...15,118,043
JBrowse link
G KLK12 kallikrein related peptidase 12 TAS Reactome Reactome:R-HSA-6809371 NCBI chr19:51,028,954...51,035,648
Ensembl chr19:51,029,092...51,035,230
JBrowse link
G KLK13 kallikrein related peptidase 13 TAS Reactome Reactome:R-HSA-6809371 NCBI chr19:51,055,626...51,065,106
Ensembl chr19:51,055,626...51,065,114
JBrowse link
G KLK14 kallikrein related peptidase 14 TAS Reactome Reactome:R-HSA-6809371 NCBI chr19:51,077,494...51,084,210
Ensembl chr19:51,077,495...51,084,245
JBrowse link
G KLK5 kallikrein related peptidase 5 TAS Reactome Reactome:R-HSA-6809371 NCBI chr19:50,943,299...50,953,038
Ensembl chr19:50,943,303...50,953,093
JBrowse link
G KRT1 keratin 1 TAS Reactome Reactome:R-HSA-6809371 NCBI chr12:52,674,736...52,680,407
Ensembl chr12:52,674,736...52,680,407
JBrowse link
G KRT10 keratin 10 TAS Reactome Reactome:R-HSA-6809371 NCBI chr17:40,818,117...40,822,614
Ensembl chr17:40,818,117...40,822,614
JBrowse link
G KRT12 keratin 12 TAS Reactome Reactome:R-HSA-6809371 NCBI chr17:40,861,303...40,867,223
Ensembl chr17:40,861,303...40,867,223
JBrowse link
G KRT13 keratin 13 TAS Reactome Reactome:R-HSA-6809371 NCBI chr17:41,500,981...41,505,612
Ensembl chr17:41,500,981...41,505,705
JBrowse link
G KRT14 keratin 14 TAS Reactome Reactome:R-HSA-6809371 NCBI chr17:41,582,279...41,586,895
Ensembl chr17:41,582,279...41,586,895
JBrowse link
G KRT15 keratin 15 TAS Reactome Reactome:R-HSA-6809371 NCBI chr17:41,513,745...41,521,924
Ensembl chr17:41,513,745...41,522,529
JBrowse link
G KRT16 keratin 16 TAS Reactome Reactome:R-HSA-6809371 NCBI chr17:41,609,778...41,612,767
Ensembl chr17:41,609,778...41,615,899
JBrowse link
G KRT17 keratin 17 TAS Reactome Reactome:R-HSA-6809371 NCBI chr17:41,619,442...41,624,575
Ensembl chr17:41,619,442...41,624,842
JBrowse link
G KRT18 keratin 18 TAS Reactome Reactome:R-HSA-6809371 NCBI chr12:52,948,855...52,952,906
Ensembl chr12:52,948,871...52,952,906
JBrowse link
G KRT19 keratin 19 TAS Reactome Reactome:R-HSA-6809371 NCBI chr17:41,523,617...41,528,308
Ensembl chr17:41,523,617...41,528,308
JBrowse link
G KRT2 keratin 2 TAS Reactome Reactome:R-HSA-6809371 NCBI chr12:52,644,558...52,652,211
Ensembl chr12:52,644,558...52,652,211
JBrowse link
G KRT20 keratin 20 TAS Reactome Reactome:R-HSA-6809371 NCBI chr17:40,875,889...40,885,242
Ensembl chr17:40,875,889...40,885,242
JBrowse link
G KRT23 keratin 23 TAS Reactome Reactome:R-HSA-6809371 NCBI chr17:40,922,696...40,937,646
Ensembl chr17:40,922,700...40,937,646
Ensembl chr17:40,922,700...40,937,646
JBrowse link
G KRT24 keratin 24 TAS Reactome Reactome:R-HSA-6809371 NCBI chr17:40,694,246...40,703,752
Ensembl chr17:40,697,991...40,703,752
JBrowse link
G KRT25 keratin 25 TAS Reactome Reactome:R-HSA-6809371 NCBI chr17:40,748,021...40,755,542
Ensembl chr17:40,748,021...40,755,331
JBrowse link
G KRT26 keratin 26 TAS Reactome Reactome:R-HSA-6809371 NCBI chr17:40,766,238...40,772,159
Ensembl chr17:40,766,238...40,772,162
JBrowse link
G KRT27 keratin 27 TAS Reactome Reactome:R-HSA-6809371 NCBI chr17:40,776,808...40,782,550
Ensembl chr17:40,776,808...40,782,550
JBrowse link
G KRT28 keratin 28 TAS Reactome Reactome:R-HSA-6809371 NCBI chr17:40,792,196...40,799,959
Ensembl chr17:40,792,196...40,799,959
JBrowse link
G KRT3 keratin 3 TAS Reactome Reactome:R-HSA-6809371 NCBI chr12:52,789,685...52,805,735
Ensembl chr12:52,789,685...52,796,117
JBrowse link
G KRT31 keratin 31 TAS Reactome Reactome:R-HSA-6809371 NCBI chr17:41,393,721...41,397,608
Ensembl chr17:41,393,721...41,397,608
JBrowse link
G KRT32 keratin 32 TAS Reactome Reactome:R-HSA-6809371 NCBI chr17:41,459,513...41,469,252
Ensembl chr17:41,459,811...41,467,429
JBrowse link
G KRT33A keratin 33A TAS Reactome Reactome:R-HSA-6809371 NCBI chr17:41,345,704...41,350,828
Ensembl chr17:41,346,092...41,350,828
JBrowse link
G KRT33B keratin 33B TAS Reactome Reactome:R-HSA-6809371 NCBI chr17:41,363,498...41,369,813
Ensembl chr17:41,363,498...41,369,813
JBrowse link
G KRT34 keratin 34 TAS Reactome Reactome:R-HSA-6809371 NCBI chr17:41,377,665...41,383,816
Ensembl chr17:41,377,650...41,382,403
JBrowse link
G KRT35 keratin 35 TAS Reactome Reactome:R-HSA-6809371 NCBI chr17:41,476,689...41,482,743
Ensembl chr17:41,476,689...41,481,140
JBrowse link
G KRT36 keratin 36 TAS Reactome Reactome:R-HSA-6809371 NCBI chr17:41,486,136...41,489,864
Ensembl chr17:41,486,136...41,492,546
JBrowse link
G KRT37 keratin 37 TAS Reactome Reactome:R-HSA-6809371 NCBI chr17:41,420,547...41,424,585
Ensembl chr17:41,420,547...41,424,585
JBrowse link
G KRT38 keratin 38 TAS Reactome Reactome:R-HSA-6809371 NCBI chr17:41,436,154...41,440,983
Ensembl chr17:41,436,446...41,440,921
Ensembl chr17:41,436,446...41,440,921
JBrowse link
G KRT39 keratin 39 TAS Reactome Reactome:R-HSA-6809371 NCBI chr17:40,958,417...40,966,948
Ensembl chr17:40,958,417...40,966,948
JBrowse link
G KRT4 keratin 4 TAS Reactome Reactome:R-HSA-6809371 NCBI chr12:52,806,549...52,814,116
Ensembl chr12:52,806,549...52,814,116
JBrowse link
G KRT40 keratin 40 TAS Reactome Reactome:R-HSA-6809371 NCBI chr17:40,977,715...40,987,135
Ensembl chr17:40,977,716...40,987,135
JBrowse link
G KRT5 keratin 5 TAS Reactome Reactome:R-HSA-6809371 NCBI chr12:52,514,575...52,520,394
Ensembl chr12:52,514,575...52,520,530
JBrowse link
G KRT6A keratin 6A TAS Reactome Reactome:R-HSA-6809371 NCBI chr12:52,487,176...52,493,257
Ensembl chr12:52,487,176...52,493,257
JBrowse link
G KRT6B keratin 6B TAS Reactome Reactome:R-HSA-6809371 NCBI chr12:52,446,651...52,452,146
Ensembl chr12:52,446,651...52,452,146
JBrowse link
G KRT6C keratin 6C TAS Reactome Reactome:R-HSA-6809371 NCBI chr12:52,468,516...52,473,805
Ensembl chr12:52,468,516...52,473,805
JBrowse link
G KRT7 keratin 7 TAS Reactome Reactome:R-HSA-6809371 NCBI chr12:52,233,243...52,252,667
Ensembl chr12:52,232,520...52,252,186
JBrowse link
G KRT71 keratin 71 TAS Reactome Reactome:R-HSA-6809371 NCBI chr12:52,543,909...52,553,145
Ensembl chr12:52,543,909...52,553,145
JBrowse link
G KRT72 keratin 72 TAS Reactome Reactome:R-HSA-6809371 NCBI chr12:52,585,589...52,602,900
Ensembl chr12:52,585,589...52,601,538
JBrowse link
G KRT73 keratin 73 TAS Reactome Reactome:R-HSA-6809371 NCBI chr12:52,601,813...52,620,133
Ensembl chr12:52,607,570...52,618,559
JBrowse link
G KRT74 keratin 74 TAS Reactome Reactome:R-HSA-6809371 NCBI chr12:52,565,782...52,573,843
Ensembl chr12:52,565,782...52,573,843
JBrowse link
G KRT75 keratin 75 TAS Reactome Reactome:R-HSA-6809371 NCBI chr12:52,424,070...52,434,371
Ensembl chr12:52,424,070...52,434,371
JBrowse link
G KRT76 keratin 76 TAS Reactome Reactome:R-HSA-6809371 NCBI chr12:52,768,155...52,777,345
Ensembl chr12:52,768,155...52,777,345
JBrowse link
G KRT77 keratin 77 TAS Reactome Reactome:R-HSA-6809371 NCBI chr12:52,689,612...52,703,524
Ensembl chr12:52,689,626...52,703,524
JBrowse link
G KRT78 keratin 78 TAS Reactome Reactome:R-HSA-6809371 NCBI chr12:52,837,804...52,848,994
Ensembl chr12:52,837,804...52,849,092
JBrowse link
G KRT79 keratin 79 TAS Reactome Reactome:R-HSA-6809371 NCBI chr12:52,821,408...52,834,311
Ensembl chr12:52,821,408...52,834,311
JBrowse link
G KRT8 keratin 8 TAS Reactome Reactome:R-HSA-6809371 NCBI chr12:52,897,191...52,949,860
Ensembl chr12:52,897,187...52,949,954
JBrowse link
G KRT80 keratin 80 TAS Reactome Reactome:R-HSA-6809371 NCBI chr12:52,168,996...52,192,014
Ensembl chr12:52,168,996...52,192,014
JBrowse link
G KRT81 keratin 81 TAS Reactome Reactome:R-HSA-6809371 NCBI chr12:52,285,913...52,291,534
Ensembl chr12:52,285,913...52,291,534
JBrowse link
G KRT82 keratin 82 TAS Reactome Reactome:R-HSA-6809371 NCBI chr12:52,393,931...52,406,335
Ensembl chr12:52,393,931...52,406,355
Ensembl chr12:52,393,931...52,406,355
JBrowse link
G KRT83 keratin 83 TAS Reactome Reactome:R-HSA-6809371 NCBI chr12:52,314,301...52,321,398
Ensembl chr12:52,314,301...52,321,398
JBrowse link
G KRT84 keratin 84 TAS Reactome Reactome:R-HSA-6809371 NCBI chr12:52,377,665...52,386,977
Ensembl chr12:52,377,812...52,385,652
JBrowse link
G KRT85 keratin 85 TAS Reactome Reactome:R-HSA-6809371 NCBI chr12:52,360,006...52,367,481
Ensembl chr12:52,360,006...52,367,481
JBrowse link
G KRT86 keratin 86 TAS Reactome Reactome:R-HSA-6809371 NCBI chr12:52,270,507...52,309,163
Ensembl chr12:52,249,300...52,309,163
JBrowse link
G KRT9 keratin 9 TAS Reactome Reactome:R-HSA-6809371 NCBI chr17:41,565,836...41,572,059
Ensembl chr17:41,565,836...41,572,059
JBrowse link
G LCE1A late cornified envelope 1A TAS Reactome Reactome:R-HSA-6809371 NCBI chr 1:152,827,473...152,828,097
Ensembl chr 1:152,827,473...152,828,097
JBrowse link
G LCE3D late cornified envelope 3D TAS Reactome Reactome:R-HSA-6809371 NCBI chr 1:152,579,381...152,580,516
Ensembl chr 1:152,579,381...152,580,516
JBrowse link
G LIPK lipase family member K TAS Reactome Reactome:R-HSA-6809371 NCBI chr10:88,706,225...88,753,092
Ensembl chr10:88,724,544...88,752,756
JBrowse link
G LIPM lipase family member M TAS Reactome Reactome:R-HSA-6809371 NCBI chr10:88,802,730...88,822,022
Ensembl chr10:88,802,730...88,820,546
JBrowse link
G LIPN lipase family member N TAS Reactome Reactome:R-HSA-6809371 NCBI chr10:88,757,226...88,783,662
Ensembl chr10:88,759,982...88,779,626
Ensembl chr10:88,759,982...88,779,626
JBrowse link
G LOC100653049 keratin, type I cuticular Ha4 TAS Reactome Reactome:R-HSA-6809371 Ensembl chr17:41,377,650...41,382,403 JBrowse link
G LORICRIN loricrin cornified envelope precursor protein TAS Reactome Reactome:R-HSA-6809371 NCBI chr 1:153,259,635...153,262,125
Ensembl chr 1:153,259,687...153,262,124
JBrowse link
G PCSK6 proprotein convertase subtilisin/kexin type 6 TAS Reactome Reactome:R-HSA-6809371 NCBI chr15:101,303,933...101,489,707
Ensembl chr15:101,297,142...101,525,202
JBrowse link
G PERP p53 apoptosis effector related to PMP22 TAS Reactome Reactome:R-HSA-6809371 NCBI chr 6:138,088,505...138,107,419
Ensembl chr 6:138,088,505...138,107,419
JBrowse link
G PI3 peptidase inhibitor 3 TAS Reactome Reactome:R-HSA-6809371 NCBI chr20:45,174,902...45,176,544
Ensembl chr20:45,174,902...45,176,544
JBrowse link
G PKP1 plakophilin 1 TAS Reactome Reactome:R-HSA-6809371 NCBI chr 1:201,283,506...201,332,989
Ensembl chr 1:201,283,452...201,332,993
JBrowse link
G PKP2 plakophilin 2 TAS Reactome Reactome:R-HSA-6809371 NCBI chr12:32,790,755...32,896,777
Ensembl chr12:32,790,745...32,896,840
Ensembl chr12:32,790,745...32,896,840
JBrowse link
G PKP3 plakophilin 3 TAS Reactome Reactome:R-HSA-6809371 NCBI chr11:392,596...404,908
Ensembl chr11:392,614...404,908
JBrowse link
G PKP4 plakophilin 4 TAS Reactome Reactome:R-HSA-6809371 NCBI chr 2:158,456,952...158,681,429
Ensembl chr 2:158,456,952...158,682,879
Ensembl chr 2:158,456,952...158,682,879
JBrowse link
G PPL periplakin TAS Reactome Reactome:R-HSA-6809371 NCBI chr16:4,882,507...4,937,148
Ensembl chr16:4,882,507...4,960,741
JBrowse link
G PRSS8 serine protease 8 TAS Reactome Reactome:R-HSA-6809371 NCBI chr16:31,131,433...31,135,727
Ensembl chr16:31,131,433...31,135,727
JBrowse link
G RPTN repetin TAS Reactome Reactome:R-HSA-6809371 NCBI chr 1:152,153,595...152,159,228
Ensembl chr 1:152,153,595...152,159,228
JBrowse link
G SPINK5 serine peptidase inhibitor Kazal type 5 TAS Reactome Reactome:R-HSA-6809371 NCBI chr 5:148,063,980...148,137,382
Ensembl chr 5:148,025,683...148,137,289
Ensembl chr 5:148,025,683...148,137,289
JBrowse link
G SPINK6 serine peptidase inhibitor Kazal type 6 TAS Reactome Reactome:R-HSA-6809371 NCBI chr 5:148,202,778...148,215,137
Ensembl chr 5:148,202,794...148,215,137
JBrowse link
G SPINK9 serine peptidase inhibitor Kazal type 9 TAS Reactome Reactome:R-HSA-6809371 NCBI chr 5:148,323,219...148,341,974
Ensembl chr 5:148,321,203...148,339,852
JBrowse link
G SPRR1A small proline rich protein 1A TAS Reactome Reactome:R-HSA-6809371 NCBI chr 1:152,984,081...152,985,814
Ensembl chr 1:152,985,231...152,985,500
JBrowse link
G SPRR1B small proline rich protein 1B TAS Reactome Reactome:R-HSA-6809371 NCBI chr 1:153,031,203...153,032,900
Ensembl chr 1:153,031,203...153,032,900
JBrowse link
G SPRR2A small proline rich protein 2A TAS Reactome Reactome:R-HSA-6809371 NCBI chr 1:153,056,120...153,057,512
Ensembl chr 1:153,056,120...153,057,512
JBrowse link
G SPRR2B small proline rich protein 2B TAS Reactome Reactome:R-HSA-6809371 NCBI chr 1:153,070,226...153,071,611
Ensembl chr 1:153,070,224...153,070,840
JBrowse link
G SPRR2D small proline rich protein 2D TAS Reactome Reactome:R-HSA-6809371 NCBI chr 1:153,039,732...153,041,120
Ensembl chr 1:153,039,732...153,041,931
JBrowse link
G SPRR2E small proline rich protein 2E TAS Reactome Reactome:R-HSA-6809371 NCBI chr 1:153,093,135...153,094,526
Ensembl chr 1:153,093,135...153,106,184
JBrowse link
G SPRR2F small proline rich protein 2F TAS Reactome Reactome:R-HSA-6809371 NCBI chr 1:153,112,121...153,119,468
Ensembl chr 1:153,112,121...153,113,516
JBrowse link
G SPRR2G small proline rich protein 2G TAS Reactome Reactome:R-HSA-6809371 NCBI chr 1:153,149,582...153,195,377
Ensembl chr 1:153,149,582...153,150,890
JBrowse link
G SPRR3 small proline rich protein 3 TAS Reactome Reactome:R-HSA-6809371 NCBI chr 1:153,001,749...153,003,856
Ensembl chr 1:153,001,747...153,003,856
JBrowse link
G ST14 ST14 transmembrane serine protease matriptase TAS Reactome Reactome:R-HSA-6809371 NCBI chr11:130,159,782...130,210,362
Ensembl chr11:130,159,782...130,210,362
JBrowse link
G TCHH trichohyalin TAS Reactome Reactome:R-HSA-6809371 NCBI chr 1:152,106,317...152,115,444
Ensembl chr 1:152,106,317...152,115,454
JBrowse link
G TGM1 transglutaminase 1 TAS Reactome Reactome:R-HSA-6809371 NCBI chr14:24,249,114...24,263,177
Ensembl chr14:24,249,114...24,264,432
JBrowse link
G TGM5 transglutaminase 5 TAS Reactome Reactome:R-HSA-6809371 NCBI chr15:43,232,590...43,266,928
Ensembl chr15:43,232,590...43,266,928
JBrowse link
G TMEM79 transmembrane protein 79 IEA Ensembl GO_REF:0000107 NCBI chr 1:156,282,932...156,292,443
Ensembl chr 1:156,282,935...156,293,185
JBrowse link
negative regulation of cornification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDSN corneodesmosin IMP (PMID:26014679) CAFA PMID:26014679 NCBI chr 6:31,115,087...31,120,446
Ensembl chr 6:31,115,087...31,120,446
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18670
    multicellular organismal process 8775
      keratinization 229
        cornification 114
          negative regulation of cornification 1
          positive regulation of cornification 0
          regulation of cornification + 1
Path 2
Term Annotations click to browse term
  biological_process 18670
    developmental process 7464
      anatomical structure development 6871
        tissue development 2422
          epithelium development 1532
            epithelial cell differentiation 913
              epidermal cell differentiation 395
                keratinocyte differentiation 316
                  keratinization 229
                    cornification 114
                      negative regulation of cornification 1
                      positive regulation of cornification 0
                      regulation of cornification + 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.