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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular response to hydrogen peroxide
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Accession:GO:0070301 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.


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cellular response to hydrogen peroxide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link 3 10,041,820 10,145,076 RGD:1624291
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:7244243
G Aifm1 apoptosis inducing factor, mitochondria associated 1 JBrowse link X 135,304,063 135,343,062 RGD:10047407
G Akr1b1 aldo-keto reductase family 1 member B JBrowse link 4 61,706,866 61,720,959 RGD:8548771
G Ankzf1 ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1 JBrowse link 9 82,393,619 82,400,537 RGD:1624291
RGD:1600115
G Anxa1 annexin A1 JBrowse link 1 237,893,983 237,910,002 RGD:2306955
RGD:13792537
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 JBrowse link 15 27,849,943 27,852,083 RGD:634652
RGD:2315678
G Aqp1 aquaporin 1 (Colton blood group) JBrowse link 4 85,551,503 85,563,683 RGD:1624291
RGD:1600115
G Arg1 arginase 1 JBrowse link 1 21,525,421 21,537,872 RGD:4142843
G Arpc2 actin related protein 2/3 complex, subunit 2 JBrowse link 9 81,518,163 81,548,871 RGD:11049153
G Axl Axl receptor tyrosine kinase JBrowse link 1 82,550,892 82,580,761 RGD:2325835
G Becn1 beclin 1 JBrowse link 10 89,209,944 89,225,297 RGD:11561927
G Bnip3 BCL2 interacting protein 3 JBrowse link 1 211,248,098 211,265,282 RGD:5128797
G Capn1 calpain 1 JBrowse link 1 221,346,081 221,370,965 RGD:13792584
G Cbx8 chromobox 8 JBrowse link 10 108,148,073 108,150,511 RGD:9586727
G Cdk1 cyclin-dependent kinase 1 JBrowse link 20 20,576,341 20,591,510 RGD:2316486
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:1624291
G Cfh complement factor H JBrowse link 13 56,979,155 57,080,540 RGD:7364950
G Cfl1 cofilin 1 JBrowse link 1 220,869,805 220,873,337 RGD:11570554
G Cst3 cystatin C JBrowse link 3 143,219,671 143,223,544 RGD:2306497
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 JBrowse link 6 2,308,179 2,316,739 RGD:1600115
RGD:1624291
G Ect2 epithelial cell transforming 2 JBrowse link 2 112,769,385 112,831,476 RGD:1624291
RGD:1600115
G Ep300 E1A binding protein p300 JBrowse link 7 122,818,194 122,889,055 RGD:2289910
G Ets1 ETS proto-oncogene 1, transcription factor JBrowse link 8 33,756,634 33,879,625 RGD:2313718
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link 4 77,284,404 77,347,011 RGD:1624291
RGD:1600115
G F3 coagulation factor III, tissue factor JBrowse link 2 225,310,686 225,322,281 RGD:2313771
G Fabp1 fatty acid binding protein 1 JBrowse link 4 99,063,181 99,066,957 RGD:1624291
RGD:1600115
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:730260
G Foxo1 forkhead box O1 JBrowse link 2 141,451,234 141,527,016 RGD:10044264
G Fxn frataxin JBrowse link 1 242,123,975 242,152,834 RGD:1624291
RGD:1600115
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 11 65,060,884 65,208,842 RGD:10045554
G Hdac2 histone deacetylase 2 JBrowse link 20 43,084,870 43,108,198 RGD:9590229
G Hdac6 histone deacetylase 6 JBrowse link X 15,295,372 15,316,673 RGD:1624291
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:8693740
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 RGD:4889541
G Hsf1 heat shock transcription factor 1 JBrowse link 7 117,538,523 117,565,478 RGD:10402789
G Hspb1 heat shock protein family B (small) member 1 JBrowse link 12 23,839,390 23,841,051 RGD:10402758
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:4889505
G Il18bp interleukin 18 binding protein JBrowse link 1 167,091,521 167,095,727 RGD:4889505
G Il18rap interleukin 18 receptor accessory protein JBrowse link 9 47,225,543 47,255,805 RGD:4889505
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:1624291
RGD:2315678
G Impact impact RWD domain protein JBrowse link 18 4,325,872 4,346,734 RGD:1624291
RGD:1600115
G Kat5 lysine acetyltransferase 5 JBrowse link 1 220,967,795 220,974,596 RGD:2316135
G Kdm6b lysine demethylase 6B JBrowse link 10 56,000,494 56,009,582 RGD:1624291
G Klf2 Kruppel-like factor 2 JBrowse link 16 19,223,087 19,225,037 RGD:2316543
G Klf4 Kruppel like factor 4 JBrowse link 5 72,283,311 72,287,669 RGD:2316543
G Klf6 Kruppel-like factor 6 JBrowse link 17 67,887,939 67,945,052 RGD:2316543
G Lcn2 lipocalin 2 JBrowse link 3 11,414,189 11,417,534 RGD:2316500
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha JBrowse link 3 150,801,289 150,802,935 RGD:11561927
G Map3k5 mitogen-activated protein kinase kinase kinase 5 JBrowse link 1 15,412,603 15,613,752 RGD:1624291
RGD:1600115
G Mapk13 mitogen activated protein kinase 13 JBrowse link 20 6,018,374 6,027,467 RGD:1600115
RGD:1624291
G Mapk7 mitogen-activated protein kinase 7 JBrowse link 10 47,768,592 47,775,130 RGD:1624291
G Mapk8 mitogen-activated protein kinase 8 JBrowse link 16 9,620,854 9,709,342 RGD:1624291
G Mdm2 MDM2 proto-oncogene JBrowse link 7 60,719,060 60,743,618 RGD:2317364
G Mff mitochondrial fission factor JBrowse link 9 88,490,280 88,518,517 RGD:12879458
G Mif macrophage migration inhibitory factor JBrowse link 20 13,715,219 13,732,980 RGD:4890974
G Myb MYB proto-oncogene, transcription factor JBrowse link 1 16,658,178 16,690,135 RGD:11532746
G Net1 neuroepithelial cell transforming 1 JBrowse link 17 69,991,786 70,020,977 RGD:1624291
RGD:1600115
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:1624291
RGD:1600115
G Nkx2-5 NK2 homeobox 5 JBrowse link 10 16,635,989 16,638,758 RGD:12911227
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link 19 38,422,210 38,437,103 RGD:13440121
G Optn optineurin JBrowse link 17 77,167,700 77,218,374 RGD:13432574
G Oser1 oxidative stress responsive serine-rich 1 JBrowse link 3 159,784,131 159,802,923 RGD:8553799
RGD:13792537
G Park7 Parkinsonism associated deglycase JBrowse link 5 167,982,438 168,004,724 RGD:1624291
RGD:1600115
G Pax2 paired box 2 JBrowse link 1 264,493,579 264,585,073 RGD:1624291
RGD:1600115
G Pcgf2 polycomb group ring finger 2 JBrowse link 10 85,631,829 85,642,591 RGD:1624291
RGD:1600115
G Pcna proliferating cell nuclear antigen JBrowse link 3 124,880,698 124,884,570 RGD:2316486
G Pdgfd platelet derived growth factor D JBrowse link 8 4,441,010 4,666,754 RGD:9854628
G Pdgfrb platelet derived growth factor receptor beta JBrowse link 18 56,364,586 56,406,381 RGD:1624291
G Plekha1 pleckstrin homology domain containing A1 JBrowse link 1 201,429,716 201,481,411 RGD:1624291
RGD:1600115
G Ppif peptidylprolyl isomerase F JBrowse link 16 1,979,191 1,985,912 RGD:1624291
RGD:13792537
RGD:1600115
G Ppp5c protein phosphatase 5, catalytic subunit JBrowse link 1 78,944,054 78,968,361 RGD:8694078
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 JBrowse link 2 54,857,688 54,893,404 RGD:2316812
G Prkcd protein kinase C, delta JBrowse link 16 6,655,131 6,675,746 RGD:1624291
RGD:1600115
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:1624291
RGD:1600115
G Rhob ras homolog family member B JBrowse link 6 33,689,127 33,691,301 RGD:1624291
RGD:1600115
G Ripk1 receptor interacting serine/threonine kinase 1 JBrowse link 17 31,537,580 31,569,904 RGD:1600115
RGD:1624291
G Ripk3 receptor-interacting serine-threonine kinase 3 JBrowse link 15 34,470,796 34,479,741 RGD:1624291
G Rps3 ribosomal protein S3 JBrowse link 1 164,435,868 164,441,167 RGD:1624291
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:8547917
G Setx senataxin JBrowse link 3 7,680,430 7,731,815 RGD:1624291
RGD:1600115
G Sirpa signal-regulatory protein alpha JBrowse link 3 122,113,735 122,152,478 RGD:13792550
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:1624291
RGD:2290573
G Smpd3 sphingomyelin phosphodiesterase 3 JBrowse link 19 38,237,963 38,321,572 RGD:1624291
RGD:1600115
G Sphk1 sphingosine kinase 1 JBrowse link 10 105,498,728 105,504,401 RGD:2311369
RGD:1624291
G Src SRC proto-oncogene, non-receptor tyrosine kinase JBrowse link 3 153,547,807 153,595,643 RGD:1624291
RGD:1600115
G Stat6 signal transducer and activator of transcription 6 JBrowse link 7 70,946,228 70,963,542 RGD:7244148
G Tnfaip3 TNF alpha induced protein 3 JBrowse link 1 14,401,103 14,416,369 RGD:1624291
RGD:1600115
G Top2b DNA topoisomerase II beta JBrowse link 15 10,262,972 10,319,741 RGD:13432143
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 JBrowse link 8 6,811,543 6,917,534 RGD:7242941
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 JBrowse link 20 11,434,062 11,482,880 RGD:1624291
RGD:1600115
G Zfp277 zinc finger protein 277 JBrowse link 6 60,246,209 60,374,388 RGD:1624291
G Zfp580 zinc finger protein 580 JBrowse link 1 72,338,468 72,340,636 RGD:1624291
RGD:1600115
cell death in response to hydrogen peroxide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rnf112 ring finger protein 112 JBrowse link 10 47,719,034 47,726,050 RGD:1600115
RGD:1624291
G Sigmar1 sigma non-opioid intracellular receptor 1 JBrowse link 5 58,121,824 58,124,687 RGD:1600115
RGD:1624291
intrinsic apoptotic signaling pathway in response to hydrogen peroxide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdcd10 programmed cell death 10 JBrowse link 2 173,966,701 174,012,730 RGD:1624291
RGD:1600115
G Stk25 serine/threonine kinase 25 JBrowse link 9 100,767,578 100,779,715 RGD:1624291
RGD:1600115
negative regulation of hydrogen peroxide-induced cell death term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Epor erythropoietin receptor JBrowse link 8 22,969,737 22,974,468 RGD:10401070
G Gpr37 G protein-coupled receptor 37 JBrowse link 4 51,822,163 51,844,228 RGD:1624291
RGD:1600115
G Gpr37l1 G protein-coupled receptor 37-like 1 JBrowse link 13 51,985,698 51,992,547 RGD:1624291
RGD:1600115
G Hspa8 heat shock protein family A (Hsp70) member 8 JBrowse link 8 44,989,401 44,993,261 RGD:10059424
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 7 132,857,311 133,018,549 RGD:1624291
RGD:1600115
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:1624291
RGD:1600115
G Ngb neuroglobin JBrowse link 6 111,126,259 111,131,699 RGD:9743949
G Nol3 nucleolar protein 3 JBrowse link 19 37,232,567 37,236,668 RGD:10047164
RGD:10047212
G Park7 Parkinsonism associated deglycase JBrowse link 5 167,982,438 168,004,724 RGD:1624291
G Pde8a phosphodiesterase 8A JBrowse link 1 143,036,083 143,160,395 RGD:1624291
RGD:1600115
G Psap prosaposin JBrowse link 20 29,831,302 29,856,876 RGD:1624291
RGD:1600115
G Pycr1 pyrroline-5-carboxylate reductase 1 JBrowse link 10 109,817,300 109,822,218 RGD:1624291
RGD:1600115
G Rnf146 ring finger protein 146 JBrowse link 1 30,856,923 30,873,814 RGD:13524867
G Txn1 thioredoxin 1 JBrowse link 5 75,049,735 75,057,731 RGD:1624291
RGD:1600115
negative regulation of hydrogen peroxide-induced neuron death term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fbxo7 F-box protein 7 JBrowse link 7 23,815,246 23,843,505 RGD:1624291
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:1600115
RGD:1624291
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 JBrowse link 5 63,781,801 63,822,890 RGD:1624291
RGD:1600115
G Park7 Parkinsonism associated deglycase JBrowse link 5 167,982,438 168,004,724 RGD:1624291
G Rack1 receptor for activated C kinase 1 JBrowse link 10 34,149,717 34,155,198 RGD:1624291
G Reg3b regenerating family member 3 beta JBrowse link 4 109,467,272 109,470,510 RGD:9831400
negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Park7 Parkinsonism associated deglycase JBrowse link 5 167,982,438 168,004,724 RGD:1624291
RGD:1600115
G Pink1 PTEN induced kinase 1 JBrowse link 5 156,677,146 156,689,258 RGD:1624291
RGD:1600115
negative regulation of hydrogen peroxide-mediated programmed cell death term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Glrx glutaredoxin JBrowse link 2 2,606,032 2,615,944 RGD:9686063
G Hgf hepatocyte growth factor JBrowse link 4 15,435,460 15,505,377 RGD:1624291
RGD:1600115
G Hk3 hexokinase 3 JBrowse link 17 10,134,726 10,152,976 RGD:10047370
G Met MET proto-oncogene, receptor tyrosine kinase JBrowse link 4 44,747,467 44,854,628 RGD:1624291
RGD:1600115
negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hsph1 heat shock protein family H (Hsp110) member 1 JBrowse link 12 6,322,685 6,341,898 RGD:1624291
G Pink1 PTEN induced kinase 1 JBrowse link 5 156,677,146 156,689,258 RGD:8693356
RGD:1624291
G Trap1 TNF receptor-associated protein 1 JBrowse link 10 11,724,032 11,757,682 RGD:8693356
positive regulation of hydrogen peroxide-induced cell death term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxp1 forkhead box P1 JBrowse link 4 131,362,178 131,963,466 RGD:11561912
G Ripk1 receptor interacting serine/threonine kinase 1 JBrowse link 17 31,537,580 31,569,904 RGD:1624291
RGD:1600115
positive regulation of hydrogen peroxide-mediated programmed cell death term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link 3 10,041,820 10,145,076 RGD:8693407
G Endog endonuclease G JBrowse link 3 8,741,833 8,744,414 RGD:9685387
G Foxo3 forkhead box O3 JBrowse link 20 46,428,078 46,519,156 RGD:7327146
G Hdac6 histone deacetylase 6 JBrowse link X 15,295,372 15,316,673 RGD:1624291
G Pawr pro-apoptotic WT1 regulator JBrowse link 7 51,273,764 51,353,700 RGD:1624291
RGD:1600115
regulation of hydrogen peroxide-induced cell death term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Stk26 serine/threonine kinase 26 JBrowse link X 138,032,356 138,096,632 RGD:1624291
RGD:1600115
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:10047225

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19245
    cellular process 17125
      cellular response to stimulus 8664
        cellular response to chemical stimulus 3418
          cellular response to drug 611
            cellular response to hydrogen peroxide 127
              cell death in response to hydrogen peroxide + 39
              cellular detoxification of hydrogen peroxide 0
              positive regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide 0
Path 2
Term Annotations click to browse term
  biological_process 19245
    response to stimulus 10340
      response to chemical 6280
        response to oxygen-containing compound 2295
          response to reactive oxygen species 299
            cellular response to reactive oxygen species 203
              cellular response to hydrogen peroxide 127
                cell death in response to hydrogen peroxide + 39
                cellular detoxification of hydrogen peroxide 0
                positive regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.