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ONTOLOGY REPORT - ANNOTATIONS


Term:lens fiber cell development
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Accession:GO:0070307 term browser browse the term
Definition:The process whose specific outcome is the progression of a lens fiber cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a lens fiber cell fate. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.
Synonyms:exact_synonym: lens fibre cell development


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lens fiber cell development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bfsp1 beaded filament structural protein 1 IEA
ISO
IBA
GO_REF:0000107
(MGI:2673300|PMID:15037121)
PMID:21873635
Ensembl
RGD
PMID:15037121, PMID:21873635 GO_REF:0000107, MGI:2673300, RGD:13792537 NCBI chr 3:137,935,345...137,992,652
Ensembl chr 3:137,935,345...137,969,658
JBrowse link
G Bfsp2 beaded filament structural protein 2 ISO MGI:2671074 (MGI:2673300|PMID:15037121), (MGI:3717045|PMID:17065509) RGD PMID:15037121, PMID:17065509 MGI:2673300, MGI:3717045 NCBI chr 8:111,908,614...111,965,889
Ensembl chr 8:111,908,614...111,965,889
JBrowse link
G Crygb crystallin, gamma B ISO MGI:3777015 (MGI:3776178|PMID:18172107) RGD PMID:18172107 MGI:3776178 NCBI chr 9:71,796,204...71,798,265
Ensembl chr 9:71,796,204...71,798,265
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 ISO MGI:3044679|MGI:3045749|MGI:95524 (MGI:3796810|PMID:18455718), (MGI:5447585|PMID:23136392) RGD PMID:18455718, PMID:23136392 MGI:3796810, MGI:5447585 NCBI chr 1:200,590,951...200,696,946
Ensembl chr 1:200,590,953...200,696,928
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 ISO MGI:95523 (MGI:3796810|PMID:18455718) RGD PMID:18455718 MGI:3796810 NCBI chr14:82,272,322...82,287,739
Ensembl chr14:82,273,070...82,287,706
JBrowse link
G Frs2 fibroblast growth factor receptor substrate 2 ISO MGI:3045749|MGI:3768912|MGI:97385 (MGI:5447585|PMID:23136392) RGD PMID:23136392 MGI:5447585 NCBI chr 7:60,128,506...60,210,482
Ensembl chr 7:60,128,508...60,210,518
JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 ISO MGI:2386105 (MGI:4888440|PMID:21118511) RGD PMID:21118511 MGI:4888440 NCBI chr 8:22,648,323...22,739,468
Ensembl chr 8:22,648,323...22,739,468
JBrowse link
G Tmod1 tropomodulin 1 IEA
ISO
GO_REF:0000107
UniProtKB:Q6NVD9 (MGI:5475090|PMID:23144950)
Ensembl
RGD
PMID:23144950 GO_REF:0000107, MGI:5475090 NCBI chr 5:61,635,244...61,712,052
Ensembl chr 5:61,657,507...61,712,051
JBrowse link
G Vim vimentin IEA
ISO
GO_REF:0000107
(MGI:2673300|PMID:15037121)
Ensembl
RGD
PMID:15037121 GO_REF:0000107, MGI:2673300 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
lens fiber cell morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi2 abl-interactor 2 ISO (MGI:3525751|PMID:15572692) RGD PMID:15572692 MGI:3525751 NCBI chr 9:67,234,612...67,284,504
Ensembl chr 9:67,234,303...67,282,600
JBrowse link
G Atf4 activating transcription factor 4 ISS
ISO
GO_REF:0000024
(MGI:1339872|PMID:10096021), (MGI:1859108|PMID:10885750), (MGI:2158533|PMID:11806972)
UniProt
RGD
PMID:10096021, PMID:10885750, PMID:11806972 GO_REF:0000024, MGI:1339872, MGI:1859108, MGI:2158533 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Cryaa crystallin, alpha A ISO MGI:3665275|MGI:3777403 (MGI:3655912|PMID:16799046), (MGI:3775669|PMID:18056999) RGD PMID:16799046, PMID:18056999 MGI:3655912, MGI:3775669 NCBI chr20:10,438,444...10,442,189
Ensembl chr20:10,438,444...10,442,187
JBrowse link
G Crygb crystallin, gamma B ISO MGI:1857597 (MGI:3691890|PMID:12426373), (MGI:81294|PMID:8626090) RGD PMID:8626090, PMID:12426373 MGI:3691890, MGI:81294 NCBI chr 9:71,796,204...71,798,265
Ensembl chr 9:71,796,204...71,798,265
JBrowse link
G Epha2 Eph receptor A2 ISO (MGI:3831440|PMID:18948590) RGD PMID:18948590 MGI:3831440 NCBI chr 5:159,845,773...159,874,203
Ensembl chr 5:159,845,774...159,874,206
JBrowse link
G Prox1 prospero homeobox 1 ISO (PMID:11850194)
(MGI:1332720|PMID:10080188)
RGD PMID:10080188, PMID:11850194 MGI:1332720 NCBI chr13:108,382,536...108,444,107
Ensembl chr13:108,382,399...108,443,294
JBrowse link
G Tbc1d20 TBC1 domain family, member 20 ISO MGI:1856684 (MGI:5551670|PMID:24239381) RGD PMID:24239381 MGI:5551670 NCBI chr 3:147,772,006...147,790,946
Ensembl chr 3:147,772,165...147,789,158
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    cellular process 18792
      cellular developmental process 4457
        cell development 2442
          epithelial cell development 286
            lens fiber cell development 15
              lens fiber cell morphogenesis 7
Path 2
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      anatomical structure development 6268
        multicellular organism development 5743
          system development 5279
            animal organ development 4033
              sensory organ development 696
                eye development 462
                  camera-type eye development 413
                    lens development in camera-type eye 94
                      lens fiber cell differentiation 38
                        lens fiber cell development 15
                          lens fiber cell morphogenesis 7
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.