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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of ERK1 and ERK2 cascade
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Accession:GO:0070374 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
Synonyms:exact_synonym: positive regulation of ERK1 and ERK2 signaling pathway;   positive regulation of ERK1 and ERK2 signalling pathway;   positive regulation of ERK1/2 cascade;   up regulation of ERK1 and ERK2 cascade;   upregulation of ERK1 and ERK2 cascade
 narrow_synonym: activation of ERK1 and ERK2 cascade;   positive regulation of ERK1 cascade;   positive regulation of ERK2 cascade;   positive regulation of MAPK1 cascade;   positive regulation of MAPK3 cascade;   stimulation of ERK1 and ERK2 cascade
 broad_synonym: positive regulation of ERK cascade


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positive regulation of ERK1 and ERK2 cascade term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07009373.1 RGD:13792537
G AABR07019870.1 RGD:13792537
G AABR07025074.1 RGD:13792537
G AABR07030543.1 RGD:13792537
G AABR07040430.1 RGD:13792537
G AABR07040480.1 RGD:13792537
G AABR07041586.2 RGD:13792537
G AABR07060165.1 RGD:13792537
G AABR07060287.1 RGD:13792537
G AABR07067274.1 RGD:13792537
G Abca7 ATP binding cassette subfamily A member 7 JBrowse link 7 12,742,433 12,762,423 RGD:1624291
RGD:1600115
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link 3 10,041,820 10,145,076 RGD:1624291
G Abl2 ABL proto-oncogene 2, non-receptor tyrosine kinase JBrowse link 13 74,154,533 74,333,244 RGD:1624291
G AC094217.2 RGD:13792537
G Ackr3 atypical chemokine receptor 3 JBrowse link 9 97,355,881 97,367,455 RGD:1624291
RGD:1600115
G Acta2 actin alpha 2, smooth muscle JBrowse link 1 252,537,614 252,550,394 RGD:12879446
G Adam17 ADAM metallopeptidase domain 17 JBrowse link 6 43,400,525 43,448,280 RGD:13703057
RGD:1624291
G Adcyap1 adenylate cyclase activating polypeptide 1 JBrowse link 9 121,705,897 121,725,736 RGD:8554519
RGD:13792537
RGD:1624291
G Adra1a adrenoceptor alpha 1A JBrowse link 15 43,296,997 43,398,314 RGD:5688340
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:1600115
RGD:1624291
G Akap12 A-kinase anchoring protein 12 JBrowse link 1 40,816,130 40,906,582 RGD:14348968
G Alkal1 ALK and LTK ligand 1 JBrowse link 5 12,896,136 12,925,571 RGD:1624291
RGD:13792537
G Alkal2 ALK and LTK ligand 2 JBrowse link 6 49,824,725 49,834,921 RGD:1624291
RGD:13792537
G Alox15 arachidonate 15-lipoxygenase JBrowse link 10 56,953,692 56,962,145 RGD:1624291
RGD:1600115
G Angpt1 angiopoietin 1 JBrowse link 7 81,338,327 81,592,459 RGD:1600115
RGD:1624291
G Apoe apolipoprotein E JBrowse link 1 80,612,894 80,616,820 RGD:1600115
RGD:1624291
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:12790656
RGD:1624291
G Arhgap8 Rho GTPase activating protein 8 JBrowse link 7 125,732,300 125,797,149 RGD:1624291
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 JBrowse link 2 187,964,100 188,022,847 RGD:1624291
G Arrb1 arrestin, beta 1 JBrowse link 1 164,502,099 164,573,947 RGD:5509998
RGD:13792537
RGD:1624291
G Arrb2 arrestin, beta 2 JBrowse link 10 57,040,252 57,048,045 RGD:5510006
RGD:13792537
RGD:1624291
RGD:5509898
RGD:13506828
G Atp6ap1 ATPase H+ transporting accessory protein 1 JBrowse link X 156,407,973 156,415,053 RGD:1600115
RGD:1624291
G Atp6v0c ATPase H+ transporting V0 subunit C JBrowse link 10 13,537,031 13,543,407 RGD:14700553
G Bmp2 bone morphogenetic protein 2 JBrowse link 3 126,335,963 126,346,771 RGD:1600115
RGD:1624291
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1624291
RGD:1600115
G Bmper BMP-binding endothelial regulator JBrowse link 8 24,369,916 24,615,484 RGD:1624291
G Braf B-Raf proto-oncogene, serine/threonine kinase JBrowse link 4 67,389,331 67,520,549 RGD:2315869
RGD:1624291
G C1qtnf3 C1q and TNF related 3 JBrowse link 2 60,920,160 60,942,586 RGD:1624291
G C3 complement C3 JBrowse link 9 9,721,137 9,747,084 RGD:5129534
G C5ar1 complement C5a receptor 1 JBrowse link 1 78,186,777 78,195,132 RGD:1624291
RGD:1600115
G C5ar2 complement component 5a receptor 2 JBrowse link 1 78,165,155 78,183,426 RGD:1600115
G Calcr calcitonin receptor JBrowse link 4 28,627,439 28,702,559 RGD:1624291
G Camk2d calcium/calmodulin-dependent protein kinase II delta JBrowse link 2 230,900,907 231,132,207 RGD:6907067
G Casr calcium-sensing receptor JBrowse link 11 67,188,204 67,262,261 RGD:7207059
G Cavin3 caveolae associated protein 3 JBrowse link 1 170,317,099 170,318,688 RGD:1624291
G Ccl1 C-C motif chemokine ligand 1 JBrowse link 10 69,534,976 69,537,836 RGD:13792537
G Ccl11 C-C motif chemokine ligand 11 JBrowse link 10 69,434,965 69,439,566 RGD:13792537
G Ccl12 chemokine (C-C motif) ligand 12 JBrowse link 10 69,476,866 69,478,416 RGD:13792537
G Ccl17 C-C motif chemokine ligand 17 JBrowse link 19 10,619,220 10,620,671 RGD:13792537
G Ccl19 C-C motif chemokine ligand 19 JBrowse link 5 58,181,025 58,182,969 RGD:1624291
RGD:13792537
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:13792537
G Ccl20 C-C motif chemokine ligand 20 JBrowse link 9 88,918,359 88,921,017 RGD:13792537
G Ccl21 C-C motif chemokine ligand 21 JBrowse link 5 58,197,678 58,198,782 RGD:1624291
RGD:13792537
G Ccl22 C-C motif chemokine ligand 22 JBrowse link 19 10,674,189 10,681,145 RGD:13792537
G Ccl24 C-C motif chemokine ligand 24 JBrowse link 12 24,131,529 24,152,626 RGD:13792537
G Ccl25 C-C motif chemokine ligand 25 JBrowse link 12 2,429,492 2,438,928 RGD:13792537
G Ccl26 C-C motif chemokine ligand 26 JBrowse link 12 24,157,182 24,161,870 RGD:13792537
G Ccl3 C-C motif chemokine ligand 3 JBrowse link 10 70,869,516 70,871,066 RGD:1624291
RGD:13792537
RGD:1600115
G Ccl4 C-C motif chemokine ligand 4 JBrowse link 10 70,870,926 70,886,357 RGD:13792537
G Ccl5 C-C motif chemokine ligand 5 JBrowse link 10 70,739,764 70,744,303 RGD:13792537
G Ccl6 chemokine (C-C motif) ligand 6 JBrowse link 10 70,798,118 70,802,750 RGD:13792537
G Ccl7 C-C motif chemokine ligand 7 JBrowse link 10 69,423,083 69,424,933 RGD:13792537
G Ccl9 chemokine (C-C motif) ligand 9 JBrowse link 10 70,783,426 70,788,372 RGD:13792537
G Ccn2 cellular communication network factor 2 JBrowse link 1 21,851,657 21,854,773 RGD:1624291
G Ccr1 C-C motif chemokine receptor 1 JBrowse link 8 132,996,646 133,002,201 RGD:1624291
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:1624291
G Cd4 Cd4 molecule JBrowse link 4 157,381,862 157,408,357 RGD:1624291
RGD:13792537
G Cd44 CD44 molecule (Indian blood group) JBrowse link 3 92,695,083 92,783,820 RGD:1624291
RGD:13792537
RGD:1600115
G Cd74 CD74 molecule JBrowse link 18 56,071,420 56,080,851 RGD:1624291
RGD:1600115
G Cflar CASP8 and FADD-like apoptosis regulator JBrowse link 9 65,534,608 65,586,395 RGD:11341713
G Chi3l1 chitinase 3 like 1 JBrowse link 13 51,022,844 51,030,797 RGD:1624291
RGD:1600115
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit JBrowse link 1 123,897,341 124,039,263 RGD:1600115
RGD:1624291
RGD:12790656
RGD:12050111
G Cib1 calcium and integrin binding 1 JBrowse link 1 142,014,962 142,020,461 RGD:1624291
RGD:1600115
G Crkl CRK like proto-oncogene, adaptor protein JBrowse link 11 87,338,606 87,356,644 RGD:1624291
G Csf1r colony stimulating factor 1 receptor JBrowse link 18 56,414,493 56,458,300 RGD:1600115
RGD:1624291
G Cx3cl1 C-X3-C motif chemokine ligand 1 JBrowse link 19 10,644,267 10,654,861 RGD:13792537
G Cysltr2 cysteinyl leukotriene receptor 2 JBrowse link 15 54,903,290 54,941,742 RGD:5144006
G Dcc DCC netrin 1 receptor JBrowse link 18 66,518,213 67,629,801 RGD:2314384
G Ddt D-dopachrome tautomerase JBrowse link 20 13,827,153 13,829,624 RGD:1624291
G Dennd2b DENN domain containing 2B JBrowse link 1 174,137,120 174,290,533 RGD:1624291
G Dnajc27 DnaJ heat shock protein family (Hsp40) member C27 JBrowse link 6 28,515,054 28,544,756 RGD:1624291
G Drd2 dopamine receptor D2 JBrowse link 8 53,678,777 53,743,643 RGD:2311559
G Dstyk dual serine/threonine and tyrosine protein kinase JBrowse link 13 49,195,325 49,243,327 RGD:1624291
RGD:1600115
G Dusp15 dual specificity phosphatase 15 JBrowse link 3 148,417,990 148,428,494 RGD:12903239
G Ednra endothelin receptor type A JBrowse link 19 33,928,356 33,991,703 RGD:4892323
G Egf epidermal growth factor JBrowse link 2 68,820,616 68,895,537 RGD:1626216
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:1624291
G Epo erythropoietin JBrowse link 12 22,274,828 22,278,268 RGD:10400910
G Epor erythropoietin receptor JBrowse link 8 22,969,737 22,974,468 RGD:10400910
G Erbb4 erb-b2 receptor tyrosine kinase 4 JBrowse link 9 75,021,790 76,178,936 RGD:1600115
RGD:1624291
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:5128669
G Esr2 estrogen receptor 2 JBrowse link 6 99,163,953 99,214,711 RGD:5128669
RGD:10045880
G F2r coagulation factor II (thrombin) receptor JBrowse link 2 26,118,760 26,135,340 RGD:1624291
RGD:1600115
G F2rl1 F2R like trypsin receptor 1 JBrowse link 2 25,222,324 25,235,275 RGD:1624291
RGD:1600115
G Fbxw7 F-box and WD repeat domain containing 7 JBrowse link 2 184,230,191 184,309,805 RGD:1624291
G Ffar4 free fatty acid receptor 4 JBrowse link 1 256,786,124 256,804,156 RGD:1624291
RGD:1600115
G Fga fibrinogen alpha chain JBrowse link 2 181,997,562 182,013,726 RGD:1624291
RGD:1600115
G Fgb fibrinogen beta chain JBrowse link 2 182,028,044 182,035,026 RGD:1624291
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:1624291
G Fgf18 fibroblast growth factor 18 JBrowse link 10 18,047,109 18,082,290 RGD:1624291
RGD:1600115
G Fgf19 fibroblast growth factor 19 JBrowse link 1 218,058,405 218,061,693 RGD:1624291
G Fgf2 fibroblast growth factor 2 JBrowse link 2 124,081,072 124,134,133 RGD:1624291
RGD:2325174
G Fgf20 fibroblast growth factor 20 JBrowse link 16 55,152,748 55,159,352 RGD:8553960
G Fgf21 fibroblast growth factor 21 JBrowse link 1 101,595,579 101,596,822 RGD:1624291
G Fgf23 fibroblast growth factor 23 JBrowse link 4 159,622,404 159,630,082 RGD:1624291
G Fgf4 fibroblast growth factor 4 JBrowse link 1 218,024,537 218,029,539 RGD:1624291
G Fgf8 fibroblast growth factor 8 JBrowse link 1 265,492,949 265,498,965 RGD:1624291
G Fgfbp3 fibroblast growth factor binding protein 3 JBrowse link 1 255,555,050 255,557,055 RGD:1624291
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:1624291
G Fgfr3 fibroblast growth factor receptor 3 JBrowse link 14 82,272,322 82,287,739 RGD:1624291
G Fgfr4 fibroblast growth factor receptor 4 JBrowse link 17 9,990,072 10,004,339 RGD:1624291
RGD:13792537
RGD:1600115
G Fgg fibrinogen gamma chain JBrowse link 2 181,987,080 181,994,523 RGD:1624291
G Flt4 Fms related receptor tyrosine kinase 4 JBrowse link 10 35,078,782 35,120,296 RGD:1600115
RGD:1624291
G Fpr2 formyl peptide receptor 2 JBrowse link 1 59,800,558 59,809,507 RGD:12907556
RGD:12910993
RGD:1624291
G Fshr follicle stimulating hormone receptor JBrowse link 6 12,796,383 12,997,817 RGD:1624291
RGD:1600115
G Garem1 GRB2 associated regulator of MAPK1 subtype 1 JBrowse link 18 14,982,604 15,007,245 RGD:1624291
G Gas6 growth arrest specific 6 JBrowse link 16 81,213,364 81,243,824 RGD:1624291
G Gata4 GATA binding protein 4 JBrowse link 15 46,386,703 46,458,679 RGD:1624291
G Gcg glucagon JBrowse link 3 48,442,635 48,451,650 RGD:1600115
RGD:1624291
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 (I blood group) JBrowse link 17 21,634,546 21,677,477 RGD:1624291
G Glipr2 GLI pathogenesis-related 2 JBrowse link 5 59,415,415 59,446,732 RGD:1624291
G Gnai2 G protein subunit alpha i2 JBrowse link 8 116,370,730 116,391,337 RGD:728462
G Gpbar1 G protein-coupled bile acid receptor 1 JBrowse link 9 81,555,914 81,560,931 RGD:14700993
G Gper1 G protein-coupled estrogen receptor 1 JBrowse link 12 17,309,122 17,315,267 RGD:4892081
RGD:1624291
RGD:1600115
RGD:8553942
RGD:8553898
RGD:4892084
G Gpnmb glycoprotein nmb JBrowse link 4 78,694,447 78,715,685 RGD:1624291
G Gpr183 G protein-coupled receptor 183 JBrowse link 15 108,364,701 108,376,221 RGD:1600115
RGD:1624291
G Gpr55 G protein-coupled receptor 55 JBrowse link 9 92,961,431 93,011,157 RGD:1624291
G Hand2 heart and neural crest derivatives expressed 2 JBrowse link 16 36,371,489 36,373,551 RGD:1624291
RGD:1600115
G Havcr2 hepatitis A virus cellular receptor 2 JBrowse link 10 31,561,838 31,590,624 RGD:1624291
G Hcrtr1 hypocretin receptor 1 JBrowse link 5 148,346,029 148,355,404 RGD:1624291
G Hmg1l1 high-mobility group (nonhistone chromosomal) protein 1-like 1 JBrowse link 19 59,984,234 59,985,494 RGD:13792537
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:1624291
RGD:13792537
G Hmgb4 high-mobility group box 4 JBrowse link 5 146,445,545 146,446,227 RGD:13792537
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link 2 27,480,224 27,500,654 RGD:5508698
G Hras HRas proto-oncogene, GTPase JBrowse link 1 214,178,404 214,181,841 RGD:2314843
RGD:1624291
G Htr2a 5-hydroxytryptamine receptor 2A JBrowse link 15 56,666,152 56,732,469 RGD:1624291
G Htr2b 5-hydroxytryptamine receptor 2B JBrowse link 9 93,112,781 93,130,135 RGD:1600115
RGD:1624291
G Htr2c 5-hydroxytryptamine receptor 2C JBrowse link X 118,084,520 118,318,040 RGD:1624291
G Iapp islet amyloid polypeptide JBrowse link 4 176,509,863 176,517,903 RGD:1624291
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:1624291
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:2311095
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:1358666
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:2306937
RGD:5128677
G Itgb3 integrin subunit beta 3 JBrowse link 10 92,667,869 92,783,413 RGD:4892659
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:1624291
G Kars lysyl-tRNA synthetase JBrowse link 19 44,212,205 44,231,209 RGD:1624291
G Kdr kinase insert domain receptor JBrowse link 14 34,727,677 34,787,127 RGD:1624291
RGD:1600115
G Lgals9 galectin 9 JBrowse link 10 64,737,022 64,760,195 RGD:1624291
G LOC100912649 uncharacterized LOC100912649 RGD:11534624
G LOC102548927 high mobility group protein B4-like JBrowse link X 53,234,043 53,235,377 RGD:13792537
G LOC108349258 high mobility group protein B4-like JBrowse link X 142,344,626 142,345,439 RGD:13792537
G LOC108350839 high mobility group protein B1-like JBrowse link 4 92,431,517 92,432,354 RGD:13792537
G LOC681067 similar to RIKEN cDNA 1700001F22 JBrowse link X 132,424,185 132,424,955 RGD:13792537
G LOC690117 similar to High mobility group protein 1 (HMG-1) (High mobility group protein B1) (Amphoterin) (Heparin-binding protein p30) JBrowse link 16 37,500,017 37,502,245 RGD:13792537
G LOC691030 similar to RIKEN cDNA 1700001F22 JBrowse link X 130,794,079 130,794,824 RGD:13792537
G Lrp1 LDL receptor related protein 1 JBrowse link 7 70,846,313 70,927,028 RGD:13800516
G Map2k1 mitogen activated protein kinase kinase 1 JBrowse link 8 69,134,218 69,722,573 RGD:1624291
RGD:1600115
G Map2k7 mitogen activated protein kinase kinase 7 JBrowse link 12 2,546,278 2,555,310 RGD:1600115
RGD:1624291
G Map3k12 mitogen activated protein kinase kinase kinase 12 JBrowse link 7 144,102,275 144,120,306 RGD:1600115
RGD:1624291
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:1624291
G Marco macrophage receptor with collagenous structure JBrowse link 16 85,115,199 85,147,683 RGD:12907556
G Mfhas1 malignant fibrous histiocytoma amplified sequence 1 JBrowse link 16 60,120,457 60,208,550 RGD:1624291
G Mif macrophage migration inhibitory factor JBrowse link 20 13,715,219 13,732,980 RGD:1624291
G Mt3 metallothionein 3 JBrowse link 19 11,324,708 11,326,112 RGD:1624291
RGD:13792537
RGD:1600115
G Mturn maturin, neural progenitor differentiation regulator homolog JBrowse link 4 84,854,341 84,875,300 RGD:1600115
RGD:1624291
G Musk muscle associated receptor tyrosine kinase JBrowse link 5 75,392,790 75,498,694 RGD:13792537
G Myh9 myosin, heavy chain 9 JBrowse link 7 118,740,005 118,792,507 RGD:12798521
G Ndrg4 NDRG family member 4 JBrowse link 19 9,766,439 9,802,396 RGD:1624291
RGD:13792537
RGD:1600115
RGD:10047195
G Necab2 N-terminal EF-hand calcium binding protein 2 JBrowse link 19 52,086,325 52,112,633 RGD:1624291
G Nelfe negative elongation factor complex member E JBrowse link 20 4,530,328 4,536,085 RGD:9693721
G Ngf nerve growth factor JBrowse link 2 204,886,158 204,939,523 RGD:1626216
G Nod1 nucleotide-binding oligomerization domain containing 1 JBrowse link 4 85,123,965 85,175,206 RGD:1624291
G Nod2 nucleotide-binding oligomerization domain containing 2 JBrowse link 19 19,342,061 19,389,366 RGD:1624291
G Nodal nodal growth differentiation factor JBrowse link 20 31,035,729 31,044,096 RGD:1624291
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
G Notch2 notch receptor 2 JBrowse link 2 200,187,184 200,320,403 RGD:1600115
RGD:1624291
G Nox4 NADPH oxidase 4 JBrowse link 1 150,796,359 150,976,186 RGD:1624291
G Npnt nephronectin JBrowse link 2 238,001,767 238,068,886 RGD:1624291
RGD:1600115
G Npsr1 neuropeptide S receptor 1 JBrowse link 8 25,246,174 25,483,582 RGD:9831201
G Nptn neuroplastin JBrowse link 8 63,379,062 63,445,694 RGD:2325174
G Npy neuropeptide Y JBrowse link 4 79,557,856 79,565,059 RGD:10448272
G Npy5r neuropeptide Y receptor Y5 JBrowse link 16 24,796,685 24,805,730 RGD:10448272
G Nqo2 N-ribosyldihydronicotinamide:quinone reductase 2 JBrowse link 17 32,131,847 32,158,559 RGD:11073697
G Nrp1 neuropilin 1 JBrowse link 19 61,332,351 61,486,166 RGD:1624291
G Nrxn1 neurexin 1 JBrowse link 6 13,886,757 15,191,660 RGD:1624291
G Ntrk1 neurotrophic receptor tyrosine kinase 1 JBrowse link 2 187,143,568 187,160,373 RGD:1624291
RGD:13792537
RGD:1600115
G Ntrk2 neurotrophic receptor tyrosine kinase 2 JBrowse link 17 5,934,651 6,245,778 RGD:13792537
G Ntrk3 neurotrophic receptor tyrosine kinase 3 JBrowse link 1 139,890,537 140,262,503 RGD:13792537
G Ntsr2 neurotensin receptor 2 JBrowse link 6 41,917,065 41,923,780 RGD:9743898
G Olr35 olfactory receptor 35 JBrowse link 1 164,706,276 164,707,195 RGD:1624291
G Oprm1 opioid receptor, mu 1 JBrowse link 1 43,454,803 43,704,948 RGD:8656005
G P2ry1 purinergic receptor P2Y1 JBrowse link 2 151,314,818 151,320,312 RGD:8554370
G P2ry6 pyrimidinergic receptor P2Y6 JBrowse link 1 165,972,439 166,008,348 RGD:1624291
G Pde8a phosphodiesterase 8A JBrowse link 1 143,036,083 143,160,395 RGD:1624291
RGD:13792537
G Pdgfa platelet derived growth factor subunit A JBrowse link 12 17,734,141 17,756,186 RGD:1600115
RGD:13792537
RGD:1624291
G Pdgfb platelet derived growth factor subunit B JBrowse link 7 121,215,458 121,233,092 RGD:1600115
RGD:13792537
RGD:1624291
G Pdgfc platelet derived growth factor C JBrowse link 2 179,952,227 180,126,897 RGD:13792537
G Pdgfd platelet derived growth factor D JBrowse link 8 4,441,010 4,666,754 RGD:13792537
G Pdgfra platelet derived growth factor receptor alpha JBrowse link 14 35,527,926 35,581,130 RGD:1624291
RGD:1600115
G Pdgfrb platelet derived growth factor receptor beta JBrowse link 18 56,364,586 56,406,381 RGD:1624291
RGD:1600115
G Phb prohibitin JBrowse link 10 83,476,107 83,488,878 RGD:1624291
G Phb2 prohibitin 2 JBrowse link 4 157,230,769 157,235,375 RGD:1624291
G Pla2g2a phospholipase A2 group IIA JBrowse link 5 157,282,650 157,285,295 RGD:1624291
G Pla2g5 phospholipase A2, group V JBrowse link 5 157,247,601 157,268,968 RGD:1624291
G Prkca protein kinase C, alpha JBrowse link 10 96,186,509 96,585,168 RGD:8554603
G Prkcz protein kinase C, zeta JBrowse link 5 172,658,071 172,769,492 RGD:8554313
RGD:1600115
RGD:1624291
G Prkd2 protein kinase D2 JBrowse link 1 78,767,911 78,796,223 RGD:1624291
RGD:1600115
G Prxl2c peroxiredoxin like 2C JBrowse link 17 1,798,224 1,830,011 RGD:1624291
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:1624291
G Ptk2b protein tyrosine kinase 2 beta JBrowse link 15 42,827,306 42,947,796 RGD:1624291
RGD:1600115
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 JBrowse link 12 40,895,515 40,955,999 RGD:1624291
RGD:1600115
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 JBrowse link 2 206,342,066 206,390,348 RGD:1624291
RGD:13792537
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 13 55,061,561 55,174,150 RGD:1624291
G Pycard PYD and CARD domain containing JBrowse link 1 199,438,029 199,439,062 RGD:1624291
G Ramp3 receptor activity modifying protein 3 JBrowse link 14 86,922,223 86,939,722 RGD:1624291
G Rap1a RAP1A, member of RAS oncogene family JBrowse link 2 208,193,950 208,215,186 RGD:1624291
RGD:8554481
G Rap1b RAP1B, member of RAS oncogene family JBrowse link 7 60,850,406 60,878,226 RGD:1624291
G Rapgef1 Rap guanine nucleotide exchange factor 1 JBrowse link 3 8,189,594 8,307,077 RGD:11534985
G Rapgef2 Rap guanine nucleotide exchange factor 2 JBrowse link 2 177,836,191 178,057,378 RGD:8554481
RGD:1624291
RGD:1600115
G Rara retinoic acid receptor, alpha JBrowse link 10 86,838,819 86,884,224 RGD:8553301
G Rasgrp1 RAS guanyl releasing protein 1 JBrowse link 3 108,984,029 109,044,420 RGD:1624291
G RGD1560585 similar to RIKEN cDNA 1700001F22 JBrowse link X 144,001,166 144,001,891 RGD:13792537
G RGD1561558 similar to RIKEN cDNA 1700001F22 JBrowse link X 158,261,123 158,261,953 RGD:13792537
G RGD1566225 similar to RIKEN cDNA 1700001F22 JBrowse link X 137,197,195 137,197,990 RGD:13792537
G Ripk2 receptor-interacting serine-threonine kinase 2 JBrowse link 5 29,838,713 29,870,390 RGD:1624291
G Ror1 receptor tyrosine kinase-like orphan receptor 1 JBrowse link 5 118,892,874 119,239,528 RGD:13792537
G Ror2 receptor tyrosine kinase-like orphan receptor 2 JBrowse link 17 11,953,552 12,134,386 RGD:13792537
G RT1-Db1 RT1 class II, locus Db1 JBrowse link 20 4,087,621 4,097,190 RGD:1624291
G Scimp SLP adaptor and CSK interacting membrane protein JBrowse link 10 57,415,429 57,436,412 RGD:1624291
G Sema7a semaphorin 7A (John Milton Hagen blood group) JBrowse link 8 62,723,788 62,746,530 RGD:1624291
RGD:13792537
G Serpinf2 serpin family F member 2 JBrowse link 10 62,264,247 62,272,353 RGD:1624291
G Shc1 SHC adaptor protein 1 JBrowse link 2 188,745,503 188,757,066 RGD:1600115
RGD:1624291
G Slamf1 signaling lymphocytic activation molecule family member 1 JBrowse link 13 90,184,545 90,219,170 RGD:1624291
G Slc30a10 solute carrier family 30, member 10 JBrowse link 13 103,396,295 103,406,759 RGD:1624291
G Spry2 sprouty RTK signaling antagonist 2 JBrowse link 15 90,172,769 90,177,823 RGD:1624291
G Src SRC proto-oncogene, non-receptor tyrosine kinase JBrowse link 3 153,547,807 153,595,643 RGD:8553998
RGD:1624291
G Sstr4 somatostatin receptor 4 JBrowse link 3 142,739,781 142,741,644 RGD:2325010
G Tek TEK receptor tyrosine kinase JBrowse link 5 113,725,717 113,852,799 RGD:1624291
G Tff2 trefoil factor 2 JBrowse link 20 9,872,669 9,876,008 RGD:1624291
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
RGD:1600115
G Thpo thrombopoietin JBrowse link 11 82,845,676 82,853,439 RGD:1624291
RGD:13792537
RGD:1600115
G Thpol1 thrombopoietin like 1 JBrowse link 11 83,867,549 83,874,670 RGD:1600115
RGD:13792537
G Tirap TIR domain containing adaptor protein JBrowse link 8 36,382,029 36,399,625 RGD:1624291
G Tlr2 toll-like receptor 2 JBrowse link 2 182,840,171 182,846,061 RGD:1624291
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:1624291
RGD:1600115
G Tnfaip8l3 TNF alpha induced protein 8 like 3 JBrowse link 8 58,599,382 58,648,045 RGD:1624291
G Trem2 triggering receptor expressed on myeloid cells 2 JBrowse link 9 14,611,541 14,618,076 RGD:1624291
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 JBrowse link 12 47,698,915 47,737,902 RGD:1624291
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:1624291
G Vegfb vascular endothelial growth factor B JBrowse link 1 222,237,000 222,242,786 RGD:1624291
G Xcl1 X-C motif chemokine ligand 1 JBrowse link 13 83,199,402 83,202,845 RGD:13792537
positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tnfrsf11a TNF receptor superfamily member 11A JBrowse link 13 25,778,306 25,835,802 RGD:1624291
G Tnfsf11 TNF superfamily member 11 JBrowse link 15 60,482,527 60,512,704 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19439
    cellular process 18178
      signal transduction 6902
        signal transduction by protein phosphorylation 848
          MAPK cascade 828
            positive regulation of MAPK cascade 567
              positive regulation of ERK1 and ERK2 cascade 253
                positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling 2
Path 2
Term Annotations click to browse term
  biological_process 19439
    metabolic process 11638
      organic substance metabolic process 11027
        macromolecule metabolic process 9491
          protein metabolic process 6016
            protein modification process 3849
              cellular protein modification process 3849
                protein phosphorylation 1966
                  signal transduction by protein phosphorylation 848
                    MAPK cascade 828
                      regulation of MAPK cascade 769
                        positive regulation of MAPK cascade 567
                          positive regulation of ERK1 and ERK2 cascade 253
                            positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.