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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of ERK1 and ERK2 cascade
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Accession:GO:0070374 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
Synonyms:exact_synonym: positive regulation of ERK1 and ERK2 signaling pathway;   positive regulation of ERK1 and ERK2 signalling pathway;   positive regulation of ERK1/2 cascade;   up regulation of ERK1 and ERK2 cascade;   upregulation of ERK1 and ERK2 cascade
 narrow_synonym: activation of ERK1 and ERK2 cascade;   positive regulation of ERK1 cascade;   positive regulation of ERK2 cascade;   positive regulation of MAPK1 cascade;   positive regulation of MAPK3 cascade;   stimulation of ERK1 and ERK2 cascade
 broad_synonym: positive regulation of ERK cascade


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positive regulation of ERK1 and ERK2 cascade term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABCA7 ATP binding cassette subfamily A member 7 JBrowse link 19 1,040,107 1,065,572 RGD:2290271
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link 9 130,713,881 130,887,675 RGD:2290271
G ACKR3 atypical chemokine receptor 3 JBrowse link 2 236,537,131 236,582,358 RGD:2290271
G ADCYAP1 adenylate cyclase activating polypeptide 1 JBrowse link 18 904,384 912,172 RGD:2290271
G ADRA1A adrenoceptor alpha 1A JBrowse link 8 26,738,113 26,870,994 RGD:2290271
G AGER advanced glycosylation end-product specific receptor JBrowse link 6 32,180,968 32,184,380 RGD:2290271
G AKAP12 A-kinase anchoring protein 12 JBrowse link 6 151,239,815 151,358,559 RGD:2290271
G ALKAL1 ALK and LTK ligand 1 JBrowse link 8 52,534,037 52,565,430 RGD:2290271
G ALKAL2 ALK and LTK ligand 2 JBrowse link 2 279,558 288,872 RGD:2290271
G ALOX15 arachidonate 15-lipoxygenase JBrowse link 17 4,630,919 4,641,678 RGD:2290271
G ANGPT1 angiopoietin 1 JBrowse link 8 107,249,482 107,497,918 RGD:2290271
G APELA apelin receptor early endogenous ligand JBrowse link 4 164,877,023 164,899,063 RGD:2290271
G APOE apolipoprotein E JBrowse link 19 44,905,796 44,909,395 RGD:2290271
G APP amyloid beta precursor protein JBrowse link 21 25,880,550 26,171,128 RGD:2290271
G ARHGAP8 Rho GTPase activating protein 8 JBrowse link 22 44,752,558 44,862,784 RGD:2290271
G ARRB1 arrestin beta 1 JBrowse link 11 75,260,122 75,351,662 RGD:2290271
G ARRB2 arrestin beta 2 JBrowse link 17 4,710,619 4,721,500 RGD:2290271
G ATP6AP1 ATPase H+ transporting accessory protein 1 JBrowse link X 154,428,669 154,436,516 RGD:2290271
G BMP2 bone morphogenetic protein 2 JBrowse link 20 6,767,686 6,780,246 RGD:2290271
G BMP4 bone morphogenetic protein 4 JBrowse link 14 53,949,736 53,956,891 RGD:2290271
G BMPER BMP binding endothelial regulator JBrowse link 7 33,904,915 34,156,427 RGD:2290271
G BRAF B-Raf proto-oncogene, serine/threonine kinase JBrowse link 7 140,719,331 140,924,929 RGD:2290271
G C5AR1 complement C5a receptor 1 JBrowse link 19 47,309,861 47,322,066 RGD:2290271
G C5AR2 complement component 5a receptor 2 JBrowse link 19 47,331,614 47,347,329 RGD:2290271
G CALCR calcitonin receptor JBrowse link 7 93,424,486 93,574,730 RGD:2290271
G CASR calcium sensing receptor JBrowse link 3 122,183,668 122,291,629 RGD:2290271
G CAVIN3 caveolae associated protein 3 JBrowse link 11 6,318,946 6,320,501 RGD:2290271
G CCL1 C-C motif chemokine ligand 1 JBrowse link 17 34,360,328 34,363,233 RGD:2290271
G CCL11 C-C motif chemokine ligand 11 JBrowse link 17 34,285,742 34,288,334 RGD:2290271
G CCL13 C-C motif chemokine ligand 13 JBrowse link 17 34,356,480 34,358,610 RGD:2290271
G CCL14 C-C motif chemokine ligand 14 JBrowse link 17 35,983,288 35,986,729 RGD:2290271
G CCL15 C-C motif chemokine ligand 15 JBrowse link 17 35,997,582 36,001,553 RGD:2290271
G CCL16 C-C motif chemokine ligand 16 JBrowse link 17 35,976,493 35,983,620 RGD:2290271
G CCL17 C-C motif chemokine ligand 17 JBrowse link 16 57,396,076 57,416,063 RGD:2290271
G CCL18 C-C motif chemokine ligand 18 JBrowse link 17 36,064,272 36,072,032 RGD:2290271
G CCL19 C-C motif chemokine ligand 19 JBrowse link 9 34,689,570 34,691,276 RGD:2290271
G CCL2 C-C motif chemokine ligand 2 JBrowse link 17 34,255,285 34,257,203 RGD:2290271
G CCL20 C-C motif chemokine ligand 20 JBrowse link 2 227,813,842 227,817,556 RGD:2290271
G CCL21 C-C motif chemokine ligand 21 JBrowse link 9 34,709,005 34,710,136 RGD:2290271
G CCL22 C-C motif chemokine ligand 22 JBrowse link 16 57,358,783 57,366,189 RGD:2290271
G CCL23 C-C motif chemokine ligand 23 JBrowse link 17 36,013,056 36,018,179 RGD:2290271
G CCL24 C-C motif chemokine ligand 24 JBrowse link 7 75,810,825 75,823,372 RGD:2290271
G CCL25 C-C motif chemokine ligand 25 JBrowse link 19 8,052,318 8,062,663 RGD:2290271
G CCL26 C-C motif chemokine ligand 26 JBrowse link 7 75,769,524 75,791,597 RGD:2290271
G CCL3 C-C motif chemokine ligand 3 JBrowse link 17 36,088,256 36,090,143 RGD:2290271
G CCL3L1 C-C motif chemokine ligand 3 like 1 RGD:2290271
G CCL3L3 C-C motif chemokine ligand 3 like 3 JBrowse link 17 36,194,869 36,196,758 RGD:2290271
G CCL4 C-C motif chemokine ligand 4 JBrowse link 17 36,103,827 36,105,614 RGD:2290271
G CCL4L1 C-C motif chemokine ligand 4 like 1 RGD:2290271
G CCL4L2 C-C motif chemokine ligand 4 like 2 JBrowse link 17 36,211,063 36,212,873 RGD:2290271
G CCL5 C-C motif chemokine ligand 5 JBrowse link 17 35,871,491 35,880,360 RGD:2290271
G CCL7 C-C motif chemokine ligand 7 JBrowse link 17 34,270,221 34,272,242 RGD:2290271
G CCL8 C-C motif chemokine ligand 8 JBrowse link 17 34,319,435 34,321,402 RGD:2290271
G CCN2 cellular communication network factor 2 JBrowse link 6 131,948,176 131,951,372 RGD:2290271
G CCR1 C-C motif chemokine receptor 1 JBrowse link 3 46,201,711 46,208,313 RGD:2290271
G CCR7 C-C motif chemokine receptor 7 JBrowse link 17 40,553,769 40,565,472 RGD:2290271
G CD36 CD36 molecule JBrowse link 7 80,602,207 80,679,277 RGD:2290271
G CD4 CD4 molecule JBrowse link 12 6,789,528 6,820,810 RGD:2290271
G CD44 CD44 molecule (Indian blood group) JBrowse link 11 35,139,168 35,232,402 RGD:2290271
G CD74 CD74 molecule JBrowse link 5 150,400,041 150,412,936 RGD:2290271
G CFLAR CASP8 and FADD like apoptosis regulator JBrowse link 2 201,116,104 201,176,687 RGD:2290271
G CHI3L1 chitinase 3 like 1 JBrowse link 1 203,178,931 203,186,704 RGD:2290271
G CHRFAM7A CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion JBrowse link 15 30,360,566 30,393,849 RGD:2290271
G CHRNA7 cholinergic receptor nicotinic alpha 7 subunit JBrowse link 15 32,030,462 32,173,018 RGD:2290271
G CIB1 calcium and integrin binding 1 JBrowse link 15 90,229,975 90,265,759 RGD:2290271
G CRKL CRK like proto-oncogene, adaptor protein JBrowse link 22 20,917,407 20,953,747 RGD:2290271
G CSF1R colony stimulating factor 1 receptor JBrowse link 5 150,053,291 150,113,372 RGD:2290271
G CX3CL1 C-X3-C motif chemokine ligand 1 JBrowse link 16 57,372,490 57,385,044 RGD:2290271
G DDT D-dopachrome tautomerase JBrowse link 22 23,971,365 23,979,828 RGD:2290271
G DENND2B DENN domain containing 2B JBrowse link 11 8,693,352 8,910,951 RGD:2290271
G DNAJC27 DnaJ heat shock protein family (Hsp40) member C27 JBrowse link 2 24,943,636 24,972,094 RGD:2290271
G DRD2 dopamine receptor D2 JBrowse link 11 113,409,595 113,475,398 RGD:2290271
G DSTYK dual serine/threonine and tyrosine protein kinase JBrowse link 1 205,142,497 205,211,702 RGD:2290271
G EGFR epidermal growth factor receptor JBrowse link 7 55,019,017 55,211,628 RGD:2290271
G EPO erythropoietin JBrowse link 7 100,720,468 100,723,700 RGD:2290271
G ERBB4 erb-b2 receptor tyrosine kinase 4 JBrowse link 2 211,375,717 212,538,802 RGD:2290271
G F2R coagulation factor II thrombin receptor JBrowse link 5 76,716,126 76,735,770 RGD:2290271
G F2RL1 F2R like trypsin receptor 1 JBrowse link 5 76,819,030 76,835,315 RGD:2290271
G FBXW7 F-box and WD repeat domain containing 7 JBrowse link 4 152,320,544 152,536,873 RGD:2290271
G FFAR4 free fatty acid receptor 4 JBrowse link 10 93,566,178 93,590,072 RGD:2290271
G FGA fibrinogen alpha chain JBrowse link 4 154,583,126 154,590,742 RGD:2290271
G FGB fibrinogen beta chain JBrowse link 4 154,562,980 154,572,763 RGD:2290271
G FGF10 fibroblast growth factor 10 JBrowse link 5 44,300,247 44,389,706 RGD:2290271
G FGF18 fibroblast growth factor 18 JBrowse link 5 171,419,647 171,457,626 RGD:2290271
G FGF19 fibroblast growth factor 19 JBrowse link 11 69,698,238 69,704,022 RGD:2290271
G FGF2 fibroblast growth factor 2 JBrowse link 4 122,826,708 122,898,236 RGD:2290271
G FGF20 fibroblast growth factor 20 JBrowse link 8 16,992,181 17,002,345 RGD:2290271
G FGF21 fibroblast growth factor 21 JBrowse link 19 48,755,524 48,758,330 RGD:2290271
G FGF23 fibroblast growth factor 23 JBrowse link 12 4,368,227 4,379,712 RGD:2290271
G FGF4 fibroblast growth factor 4 JBrowse link 11 69,771,022 69,775,341 RGD:2290271
G FGF8 fibroblast growth factor 8 JBrowse link 10 101,770,130 101,780,369 RGD:2290271
G FGFR2 fibroblast growth factor receptor 2 JBrowse link 10 121,478,330 121,598,458 RGD:2290271
G FGFR3 fibroblast growth factor receptor 3 JBrowse link 4 1,793,293 1,808,872 RGD:2290271
G FGFR4 fibroblast growth factor receptor 4 JBrowse link 5 177,086,915 177,098,144 RGD:2290271
G FGG fibrinogen gamma chain JBrowse link 4 154,604,134 154,612,808 RGD:2290271
G FLT4 fms related receptor tyrosine kinase 4 JBrowse link 5 180,601,506 180,650,298 RGD:2290271
G FPR2 formyl peptide receptor 2 JBrowse link 19 51,752,026 51,770,531 RGD:2290271
G FSHR follicle stimulating hormone receptor JBrowse link 2 48,953,161 49,154,527 RGD:2290271
G GAREM1 GRB2 associated regulator of MAPK1 subtype 1 JBrowse link 18 32,263,521 32,470,882 RGD:2290271
G GAS6 growth arrest specific 6 JBrowse link 13 113,820,549 113,864,076 RGD:2290271
G GATA4 GATA binding protein 4 JBrowse link 8 11,676,931 11,760,002 RGD:2290271
G GCG glucagon JBrowse link 2 162,142,882 162,152,247 RGD:2290271
G GCNT2 glucosaminyl (N-acetyl) transferase 2 (I blood group) JBrowse link 6 10,521,283 10,629,368 RGD:2290271
G GLIPR2 GLI pathogenesis related 2 JBrowse link 9 36,136,536 36,163,913 RGD:2290271
G GNAI2 G protein subunit alpha i2 JBrowse link 3 50,227,068 50,259,362 RGD:2290271
G GPBAR1 G protein-coupled bile acid receptor 1 JBrowse link 2 218,259,496 218,263,861 RGD:2290271
G GPER1 G protein-coupled estrogen receptor 1 JBrowse link 7 1,086,807 1,093,815 RGD:2290271
G GPNMB glycoprotein nmb JBrowse link 7 23,246,766 23,275,110 RGD:2290271
G GPR183 G protein-coupled receptor 183 JBrowse link 13 99,294,273 99,307,399 RGD:2290271
G GPR55 G protein-coupled receptor 55 JBrowse link 2 230,907,318 230,961,270 RGD:2290271
G HAND2 heart and neural crest derivatives expressed 2 JBrowse link 4 173,526,091 173,530,229 RGD:2290271
G HAVCR2 hepatitis A virus cellular receptor 2 JBrowse link 5 157,085,832 157,109,044 RGD:2290271
G HCRTR1 hypocretin receptor 1 JBrowse link 1 31,617,700 31,632,518 RGD:2290271
G HMGB1 high mobility group box 1 JBrowse link 13 30,456,704 30,617,597 RGD:2290271
G HMGB1P1 high mobility group box 1 pseudogene 1 JBrowse link 20 57,487,941 57,489,130 RGD:2290271
G HMGB4 high mobility group box 4 JBrowse link 1 33,860,475 33,864,791 RGD:2290271
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link 5 75,336,334 75,362,116 RGD:2290271
G HRAS HRas proto-oncogene, GTPase JBrowse link 11 532,242 535,576 RGD:2290271
G HTR2A 5-hydroxytryptamine receptor 2A JBrowse link 13 46,831,542 46,897,076 RGD:2290271
G HTR2B 5-hydroxytryptamine receptor 2B JBrowse link 2 231,108,230 231,126,172 RGD:2290271
G HTR2C 5-hydroxytryptamine receptor 2C JBrowse link X 114,584,078 114,910,061 RGD:2290271
G IAPP islet amyloid polypeptide JBrowse link 12 21,354,960 21,379,980 RGD:2290271
G ICAM1 intercellular adhesion molecule 1 JBrowse link 19 10,271,120 10,286,615 RGD:2290271
G IL26 interleukin 26 JBrowse link 12 68,201,349 68,225,810 RGD:2290271
G JUN Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 1 58,780,791 58,784,047 RGD:2290271
G KARS1 lysyl-tRNA synthetase 1 JBrowse link 16 75,627,724 75,647,687 RGD:2290271
G KDR kinase insert domain receptor JBrowse link 4 55,078,481 55,125,595 RGD:2290271
G LGALS9 galectin 9 JBrowse link 17 27,631,172 27,649,560 RGD:2290271
G LRP1 LDL receptor related protein 1 JBrowse link 12 57,128,401 57,213,377 RGD:2290271
G MAP2K1 mitogen-activated protein kinase kinase 1 JBrowse link 15 66,386,912 66,491,544 RGD:2290271
G MAP2K7 mitogen-activated protein kinase kinase 7 JBrowse link 19 7,903,785 7,914,478 RGD:2290271
G MAP3K12 mitogen-activated protein kinase kinase kinase 12 JBrowse link 12 53,479,669 53,501,205 RGD:2290271
G MAPK3 mitogen-activated protein kinase 3 JBrowse link 16 30,114,105 30,123,309 RGD:2290271
G MARCO macrophage receptor with collagenous structure JBrowse link 2 118,942,169 118,994,664 RGD:2290271
G MFHAS1 malignant fibrous histiocytoma amplified sequence 1 JBrowse link 8 8,783,354 8,893,630 RGD:2290271
G MIF macrophage migration inhibitory factor JBrowse link 22 23,894,383 23,895,223 RGD:2290271
G MT3 metallothionein 3 JBrowse link 16 56,589,528 56,591,085 RGD:2290271
G MTURN maturin, neural progenitor differentiation regulator homolog JBrowse link 7 30,134,986 30,162,764 RGD:2290271
G MUSK muscle associated receptor tyrosine kinase JBrowse link 9 110,668,189 110,806,633 RGD:2290271
G NDRG4 NDRG family member 4 JBrowse link 16 58,463,645 58,515,403 RGD:2290271
G NECAB2 N-terminal EF-hand calcium binding protein 2 JBrowse link 16 83,968,632 84,002,776 RGD:2290271
G NELFE negative elongation factor complex member E JBrowse link 6 31,952,087 31,959,043 RGD:2290271
G NOD1 nucleotide binding oligomerization domain containing 1 JBrowse link 7 30,424,527 30,478,866 RGD:2290271
G NOD2 nucleotide binding oligomerization domain containing 2 JBrowse link 16 50,693,587 50,733,077 RGD:2290271
G NODAL nodal growth differentiation factor JBrowse link 10 70,431,936 70,447,948 RGD:2290271
G NOTCH1 notch receptor 1 JBrowse link 9 136,494,433 136,546,048 RGD:2290271
G NOTCH2 notch receptor 2 JBrowse link 1 119,911,553 120,069,703 RGD:2290271
G NOX4 NADPH oxidase 4 JBrowse link 11 89,324,353 89,589,557 RGD:2290271
G NPNT nephronectin JBrowse link 4 105,895,453 105,971,671 RGD:2290271
G NPTN neuroplastin JBrowse link 15 73,560,014 73,633,389 RGD:2290271
G NPY5R neuropeptide Y receptor Y5 JBrowse link 4 163,336,968 163,352,277 RGD:2290271
G NQO2 N-ribosyldihydronicotinamide:quinone reductase 2 JBrowse link 6 2,999,816 3,019,876 RGD:2290271
G NRP1 neuropilin 1 JBrowse link 10 33,177,491 33,334,905 RGD:2290271
G NRXN1 neurexin 1 JBrowse link 2 49,918,503 51,032,536 RGD:2290271
G NTRK1 neurotrophic receptor tyrosine kinase 1 JBrowse link 1 156,815,750 156,881,850 RGD:2290271
G NTRK2 neurotrophic receptor tyrosine kinase 2 JBrowse link 9 84,668,458 85,027,070 RGD:2290271
G NTRK3 neurotrophic receptor tyrosine kinase 3 JBrowse link 15 87,859,749 88,256,796 RGD:2290271
G OPRM1 opioid receptor mu 1 JBrowse link 6 154,010,496 154,246,867 RGD:2290271
G OR2AT4 olfactory receptor family 2 subfamily AT member 4 JBrowse link 11 75,088,692 75,096,890 RGD:2290271
G P2RY1 purinergic receptor P2Y1 JBrowse link 3 152,835,131 152,841,439 RGD:2290271
G P2RY6 pyrimidinergic receptor P2Y6 JBrowse link 11 73,264,503 73,298,625 RGD:2290271
G PDE8A phosphodiesterase 8A JBrowse link 15 84,980,467 85,139,142 RGD:2290271
G PDGFA platelet derived growth factor subunit A JBrowse link 7 497,245 520,668 RGD:2290271
G PDGFB platelet derived growth factor subunit B JBrowse link 22 39,223,359 39,244,982 RGD:2290271
G PDGFC platelet derived growth factor C JBrowse link 4 156,760,454 156,971,799 RGD:2290271
G PDGFD platelet derived growth factor D JBrowse link 11 103,907,189 104,164,147 RGD:2290271
G PDGFRA platelet derived growth factor receptor alpha JBrowse link 4 54,229,127 54,298,247 RGD:2290271
G PDGFRB platelet derived growth factor receptor beta JBrowse link 5 150,113,839 150,155,845 RGD:2290271
G PHB prohibitin JBrowse link 17 49,404,048 49,414,905 RGD:2290271
G PHB2 prohibitin 2 JBrowse link 12 6,965,327 6,970,753 RGD:2290271
G PLA2G2A phospholipase A2 group IIA JBrowse link 1 19,975,431 19,980,434 RGD:2290271
G PLA2G5 phospholipase A2 group V JBrowse link 1 20,028,349 20,091,911 RGD:2290271
G PRKCA protein kinase C alpha JBrowse link 17 66,302,613 66,810,743 RGD:2290271
G PRKCZ protein kinase C zeta JBrowse link 1 2,050,411 2,185,399 RGD:2290271
G PRKD2 protein kinase D2 JBrowse link 19 46,674,316 46,717,127 RGD:2290271
G PRXL2C peroxiredoxin like 2C JBrowse link 9 96,639,577 96,655,331 RGD:2290271
G PTEN phosphatase and tensin homolog JBrowse link 10 87,863,625 87,971,930 RGD:2290271
G PTK2B protein tyrosine kinase 2 beta JBrowse link 8 27,311,478 27,459,391 RGD:2290271
G PTPN11 protein tyrosine phosphatase non-receptor type 11 JBrowse link 12 112,418,915 112,509,918 RGD:2290271
G PTPN22 protein tyrosine phosphatase non-receptor type 22 JBrowse link 1 113,813,811 113,871,761 RGD:2290271
G PTPRC protein tyrosine phosphatase receptor type C JBrowse link 1 198,638,968 198,757,476 RGD:2290271
G PYCARD PYD and CARD domain containing JBrowse link 16 31,201,486 31,202,776 RGD:2290271
G RAMP3 receptor activity modifying protein 3 JBrowse link 7 45,157,778 45,184,250 RGD:2290271
G RAP1A RAP1A, member of RAS oncogene family JBrowse link 1 111,542,009 111,716,695 RGD:2290271
G RAP1B RAP1B, member of RAS oncogene family JBrowse link 12 68,610,899 68,671,901 RGD:2290271
G RAPGEF1 Rap guanine nucleotide exchange factor 1 JBrowse link 9 131,576,770 131,740,068 RGD:2290271
G RAPGEF2 Rap guanine nucleotide exchange factor 2 JBrowse link 4 159,104,051 159,360,173 RGD:2290271
G RASGRP1 RAS guanyl releasing protein 1 JBrowse link 15 38,488,097 38,564,814 RGD:2290271
G RIPK2 receptor interacting serine/threonine kinase 2 JBrowse link 8 89,757,816 89,791,064 RGD:2290271
G ROR1 receptor tyrosine kinase like orphan receptor 1 JBrowse link 1 63,774,017 64,181,498 RGD:2290271
G ROR2 receptor tyrosine kinase like orphan receptor 2 JBrowse link 9 91,722,598 91,950,228 RGD:2290271
G S100A7 S100 calcium binding protein A7 JBrowse link 1 153,457,744 153,460,651 RGD:2290271
G SCIMP SLP adaptor and CSK interacting membrane protein JBrowse link 17 5,208,920 5,234,860 RGD:2290271
G SEMA7A semaphorin 7A (John Milton Hagen blood group) JBrowse link 15 74,409,284 74,433,958 RGD:2290271
G SERPINF2 serpin family F member 2 JBrowse link 17 1,742,808 1,755,265 RGD:2290271
G SHC1 SHC adaptor protein 1 JBrowse link 1 154,962,298 154,974,492 RGD:2290271
G SLAMF1 signaling lymphocytic activation molecule family member 1 JBrowse link 1 160,608,100 160,647,311 RGD:2290271
G SLC30A10 solute carrier family 30 member 10 JBrowse link 1 219,910,395 219,959,098 RGD:2290271
G SPRY2 sprouty RTK signaling antagonist 2 JBrowse link 13 80,335,976 80,341,126 RGD:2290271
G SRC SRC proto-oncogene, non-receptor tyrosine kinase JBrowse link 20 37,344,685 37,405,432 RGD:2290271
G SSTR4 somatostatin receptor 4 JBrowse link 20 23,035,291 23,039,237 RGD:2290271
G SYT14P1 synaptotagmin 14 pseudogene 1 JBrowse link 4 68,060,610 68,063,297 RGD:2290271
G TEK TEK receptor tyrosine kinase JBrowse link 9 27,109,141 27,230,178 RGD:2290271
G TGFB1 transforming growth factor beta 1 JBrowse link 19 41,330,323 41,353,922 RGD:2290271
G THPO thrombopoietin JBrowse link 3 184,371,935 184,379,688 RGD:2290271
G TIRAP TIR domain containing adaptor protein JBrowse link 11 126,283,087 126,294,933 RGD:2290271
G TLR4 toll like receptor 4 JBrowse link 9 117,704,403 117,724,735 RGD:2290271
G TNF tumor necrosis factor JBrowse link 6 31,575,565 31,578,336 RGD:2290271
G TNFAIP8L3 TNF alpha induced protein 8 like 3 JBrowse link 15 51,056,601 51,105,276 RGD:2290271
G TREM2 triggering receptor expressed on myeloid cells 2 JBrowse link 6 41,158,508 41,163,116 RGD:2290271
G TRPV4 transient receptor potential cation channel subfamily V member 4 JBrowse link 12 109,783,087 109,833,398 RGD:2290271
G VEGFA vascular endothelial growth factor A JBrowse link 6 43,770,209 43,786,487 RGD:2290271
G VEGFB vascular endothelial growth factor B JBrowse link 11 64,234,584 64,239,264 RGD:2290271
G XCL1 X-C motif chemokine ligand 1 JBrowse link 1 168,574,128 168,582,069 RGD:2290271
G XCL2 X-C motif chemokine ligand 2 JBrowse link 1 168,540,768 168,543,997 RGD:2290271
positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TNFRSF11A TNF receptor superfamily member 11a JBrowse link 18 62,325,287 62,391,288 RGD:2290271
G TNFSF11 TNF superfamily member 11 JBrowse link 13 42,562,736 42,608,013 RGD:2290271

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17988
    cellular process 16263
      signal transduction 6305
        signal transduction by protein phosphorylation 949
          MAPK cascade 929
            positive regulation of MAPK cascade 549
              positive regulation of ERK1 and ERK2 cascade 217
                positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling 2
Path 2
Term Annotations click to browse term
  biological_process 17988
    metabolic process 11592
      organic substance metabolic process 11012
        macromolecule metabolic process 9482
          protein metabolic process 5904
            protein modification process 4217
              cellular protein modification process 4217
                protein phosphorylation 2011
                  signal transduction by protein phosphorylation 949
                    MAPK cascade 929
                      regulation of MAPK cascade 738
                        positive regulation of MAPK cascade 549
                          positive regulation of ERK1 and ERK2 cascade 217
                            positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.