Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:nucleotide-binding oligomerization domain containing signaling pathway
go back to main search page
Accession:GO:0070423 term browser browse the term
Definition:Any series of molecular signals generated as a consequence of binding to a nucleotide-binding oligomerization domain containing (NOD) protein.
Synonyms:exact_synonym: NOD signaling pathway;   nucleotide-binding oligomerization domain containing signalling pathway


show annotations for term's descendants           Sort by:
 
nucleotide-binding oligomerization domain containing signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP8 caspase 8 TAS Reactome Reactome:R-HSA-168638 NCBI chr 2:201,233,443...201,287,711
Ensembl chr 2:201,233,443...201,287,711
JBrowse link
G CYLD CYLD lysine 63 deubiquitinase TAS Reactome Reactome:R-HSA-168638 NCBI chr16:50,742,086...50,801,935
Ensembl chr16:50,742,050...50,801,935
JBrowse link
G IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma TAS Reactome Reactome:R-HSA-168638 NCBI chr  X:154,541,238...154,565,046
Ensembl chr  X:154,541,199...154,565,046
JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 TAS Reactome Reactome:R-HSA-168638 NCBI chr  X:154,010,507...154,019,984
Ensembl chr  X:154,010,506...154,019,902
JBrowse link
G IRAK2 interleukin 1 receptor associated kinase 2 TAS Reactome Reactome:R-HSA-168638 NCBI chr 3:10,164,919...10,243,745
Ensembl chr 3:10,164,919...10,243,745
JBrowse link
G ITCH itchy E3 ubiquitin protein ligase TAS Reactome Reactome:R-HSA-168638 NCBI chr20:34,363,273...34,511,773
Ensembl chr20:34,363,241...34,540,748
JBrowse link
G MAP2K6 mitogen-activated protein kinase kinase 6 TAS Reactome Reactome:R-HSA-168638 NCBI chr17:69,414,697...69,553,865
Ensembl chr17:69,414,697...69,553,865
JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 TAS Reactome Reactome:R-HSA-168638 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,072
JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 TAS Reactome Reactome:R-HSA-168638 NCBI chr 7:30,424,527...30,478,840
Ensembl chr 7:30,424,527...30,478,784
JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 TAS Reactome Reactome:R-HSA-168638 NCBI chr16:50,693,587...50,733,077
Ensembl chr16:50,693,588...50,734,041
JBrowse link
G PEDS1-UBE2V1 PEDS1-UBE2V1 readthrough TAS Reactome Reactome:R-HSA-168638 NCBI chr20:50,081,124...50,153,723
Ensembl chr20:50,081,124...50,153,637
JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 TAS Reactome Reactome:R-HSA-168638 NCBI chr 8:89,757,816...89,791,064
Ensembl chr 8:89,757,806...89,791,064
JBrowse link
G RPS27A ribosomal protein S27a TAS Reactome Reactome:R-HSA-168638 NCBI chr 2:55,231,903...55,235,853
Ensembl chr 2:55,231,903...55,235,853
JBrowse link
G TAB1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 TAS Reactome Reactome:R-HSA-168638 NCBI chr22:39,399,780...39,437,132
Ensembl chr22:39,399,778...39,437,060
JBrowse link
G TAB2 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 TAS Reactome Reactome:R-HSA-168638 NCBI chr 6:149,217,926...149,411,611
Ensembl chr 6:149,217,926...149,245,554
Ensembl chr 6:149,217,926...149,245,554
JBrowse link
G TAB3 TGF-beta activated kinase 1 (MAP3K7) binding protein 3 TAS Reactome Reactome:R-HSA-168638 NCBI chr  X:30,827,442...30,889,391
Ensembl chr  X:30,827,442...30,975,084
JBrowse link
G TNFAIP3 TNF alpha induced protein 3 TAS Reactome Reactome:R-HSA-168638 NCBI chr 6:137,866,317...137,883,312
Ensembl chr 6:137,867,214...137,883,312
JBrowse link
G TRAF6 TNF receptor associated factor 6 TAS Reactome Reactome:R-HSA-168638 NCBI chr11:36,483,769...36,510,313
Ensembl chr11:36,483,769...36,510,272
JBrowse link
G UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 TAS Reactome Reactome:R-HSA-168638 NCBI chr19:18,563,766...18,577,550
Ensembl chr19:18,571,730...18,577,550
JBrowse link
G UBB ubiquitin B TAS Reactome Reactome:R-HSA-168638 NCBI chr17:16,380,779...16,382,745
Ensembl chr17:16,380,798...16,382,745
JBrowse link
G UBC ubiquitin C TAS Reactome Reactome:R-HSA-168638 NCBI chr12:124,911,646...124,914,650
Ensembl chr12:124,911,604...124,917,368
JBrowse link
G UBE2N ubiquitin conjugating enzyme E2 N TAS Reactome Reactome:R-HSA-168638 NCBI chr12:93,405,684...93,442,336
Ensembl chr12:93,405,673...93,441,947
JBrowse link
G UBE2V1 ubiquitin conjugating enzyme E2 V1 TAS Reactome Reactome:R-HSA-168638 NCBI chr20:50,081,124...50,115,957
Ensembl chr20:50,081,124...50,115,959
JBrowse link
negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNFAIP3 TNF alpha induced protein 3 IEA Ensembl GO_REF:0000107 NCBI chr 6:137,866,317...137,883,312
Ensembl chr 6:137,867,214...137,883,312
JBrowse link
negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ERBIN erbb2 interacting protein IMP (PMID:16203728) UniProtKB PMID:16203728 NCBI chr 5:65,926,575...66,082,546
Ensembl chr 5:65,926,475...66,082,549
JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 IEA
IBA
IMP
(PMID:21873635)
(PMID:23991106)
Ensembl
GO_Central
UniProtKB
PMID:21873635, PMID:23991106 GO_REF:0000107 NCBI chr 1:113,813,811...113,871,761
Ensembl chr 1:113,813,811...113,871,753
JBrowse link
G TNFAIP3 TNF alpha induced protein 3 IEA Ensembl GO_REF:0000107 NCBI chr 6:137,866,317...137,883,312
Ensembl chr 6:137,867,214...137,883,312
JBrowse link
nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NFKBIA NFKB inhibitor alpha IEA Ensembl GO_REF:0000107 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,511...35,404,749
Ensembl chr14:35,401,511...35,404,749
JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 IEA Ensembl GO_REF:0000107 NCBI chr 8:89,757,816...89,791,064
Ensembl chr 8:89,757,806...89,791,064
JBrowse link
nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G INAVA innate immunity activator IMP (PMID:28436939) UniProtKB PMID:28436939 NCBI chr 1:200,891,074...200,915,742
Ensembl chr 1:200,891,048...200,915,742
JBrowse link
G IRGM immunity related GTPase M IMP (PMID:25891078) UniProtKB PMID:25891078 NCBI chr 5:150,846,521...150,902,402
Ensembl chr 5:150,846,523...150,900,736
JBrowse link
G LACC1 laccase domain containing 1 IDA (PMID:31875558) UniProt PMID:31875558 NCBI chr13:43,879,178...43,893,932
Ensembl chr13:43,879,284...43,893,932
JBrowse link
G NFKBIA NFKB inhibitor alpha IEA Ensembl GO_REF:0000107 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,511...35,404,749
Ensembl chr14:35,401,511...35,404,749
JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 IDA (PMID:12527755), (PMID:23806334) MGI PMID:12527755, PMID:23806334 NCBI chr16:50,693,587...50,733,077
Ensembl chr16:50,693,588...50,734,041
JBrowse link
G OTULIN OTU deubiquitinase with linear linkage specificity IMP (PMID:23806334) UniProtKB PMID:23806334 NCBI chr 5:14,660,794...14,716,552
Ensembl chr 5:14,664,664...14,699,850
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit IDA (PMID:12527755) MGI PMID:12527755 NCBI chr11:65,653,601...65,662,946
Ensembl chr11:65,653,597...65,663,090
JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 IDA (PMID:23806334) UniProtKB PMID:23806334 NCBI chr 8:89,757,816...89,791,064
Ensembl chr 8:89,757,806...89,791,064
JBrowse link
positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC15A4 solute carrier family 15 member 4 ISS UniProt GO_REF:0000024 NCBI chr12:128,793,194...128,823,966
Ensembl chr12:128,793,194...128,823,958
JBrowse link
G SLC46A2 solute carrier family 46 member 2 IMP (PMID:28539433) FlyBase PMID:28539433 NCBI chr 9:112,878,920...112,895,538
Ensembl chr 9:112,878,920...112,890,876
JBrowse link
G TLR4 toll like receptor 4 IEA Ensembl GO_REF:0000107 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735
JBrowse link
positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSPA1A heat shock protein family A (Hsp70) member 1A IMP (PMID:24790089) UniProtKB PMID:24790089 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946
JBrowse link
G HSPA1B heat shock protein family A (Hsp70) member 1B IMP (PMID:24790089) UniProtKB PMID:24790089 NCBI chr 6:31,827,738...31,830,254
Ensembl chr 6:31,827,738...31,830,254
JBrowse link
G PELI3 pellino E3 ubiquitin protein ligase family member 3 ISO (MGI:MGI:5562512|PMID:23892723) MGI PMID:23892723 MGI:MGI:5562512 NCBI chr11:66,466,327...66,477,337
Ensembl chr11:66,466,327...66,477,337
JBrowse link
G SLC15A3 solute carrier family 15 member 3 ISS UniProt GO_REF:0000024 NCBI chr11:60,937,084...60,952,176
Ensembl chr11:60,937,084...60,952,530
JBrowse link
G SLC15A4 solute carrier family 15 member 4 ISS UniProt GO_REF:0000024 NCBI chr12:128,793,194...128,823,966
Ensembl chr12:128,793,194...128,823,958
JBrowse link
G TLR4 toll like receptor 4 IEA Ensembl GO_REF:0000107 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735
JBrowse link
regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PELI3 pellino E3 ubiquitin protein ligase family member 3 ISO (MGI:MGI:5562512|PMID:23892723) MGI PMID:23892723 MGI:MGI:5562512 NCBI chr11:66,466,327...66,477,337
Ensembl chr11:66,466,327...66,477,337
JBrowse link
regulation of nucleotide-binding oligomerization domain containing signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIRC2 baculoviral IAP repeat containing 2 TAS (PMID:20888210) UniProtKB PMID:20888210 NCBI chr11:102,347,182...102,378,670
Ensembl chr11:102,347,211...102,378,670
JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 TAS (PMID:20888210) UniProtKB PMID:20888210 NCBI chr11:102,317,373...102,339,403
Ensembl chr11:102,317,450...102,339,403
JBrowse link
G SLC15A2 solute carrier family 15 member 2 ISS UniProt GO_REF:0000024 NCBI chr 3:121,894,401...121,944,188
Ensembl chr 3:121,894,401...121,944,188
JBrowse link
G SLC15A4 solute carrier family 15 member 4 ISS UniProt GO_REF:0000024 NCBI chr12:128,793,194...128,823,966
Ensembl chr12:128,793,194...128,823,958
JBrowse link
G XIAP X-linked inhibitor of apoptosis TAS (PMID:20888210) UniProtKB PMID:20888210 NCBI chr  X:123,859,708...123,913,972
Ensembl chr  X:123,859,724...123,913,976
Ensembl chr  X:123,859,724...123,913,976
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18650
    signaling 7200
      signal transduction 6562
        pattern recognition receptor signaling pathway 216
          cytoplasmic pattern recognition receptor signaling pathway 76
            nucleotide-binding oligomerization domain containing signaling pathway 42
              negative regulation of nucleotide-binding oligomerization domain containing signaling pathway + 3
              nucleotide-binding oligomerization domain containing 1 signaling pathway + 7
              nucleotide-binding oligomerization domain containing 2 signaling pathway + 17
              positive regulation of nucleotide-binding oligomerization domain containing signaling pathway + 7
              regulation of nucleotide-binding oligomerization domain containing signaling pathway + 14
Path 2
Term Annotations click to browse term
  biological_process 18650
    biological regulation 13283
      regulation of biological process 12625
        regulation of cellular process 12020
          signal transduction 6562
            intracellular receptor signaling pathway 299
              cytoplasmic pattern recognition receptor signaling pathway 76
                nucleotide-binding oligomerization domain containing signaling pathway 42
                  negative regulation of nucleotide-binding oligomerization domain containing signaling pathway + 3
                  nucleotide-binding oligomerization domain containing 1 signaling pathway + 7
                  nucleotide-binding oligomerization domain containing 2 signaling pathway + 17
                  positive regulation of nucleotide-binding oligomerization domain containing signaling pathway + 7
                  regulation of nucleotide-binding oligomerization domain containing signaling pathway + 14
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.