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ONTOLOGY REPORT - ANNOTATIONS


Term:nucleotide-binding oligomerization domain containing signaling pathway
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Accession:GO:0070423 term browser browse the term
Definition:Any series of molecular signals generated as a consequence of binding to a nucleotide-binding oligomerization domain containing (NOD) protein.
Synonyms:exact_synonym: NOD signaling pathway;   nucleotide-binding oligomerization domain containing signalling pathway


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negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfaip3 tumor necrosis factor, alpha-induced protein 3 IMP (MGI:MGI:3777503|PMID:18342009) BHF-UCL PMID:18342009 MGI:MGI:3777503 NCBI chr10:19,000,910...19,015,410
Ensembl chr10:19,000,910...19,015,657
JBrowse link
negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Erbin Erbb2 interacting protein IMP
ISO
(MGI:MGI:5640951|PMID:16203728) UniProtKB
MGI
PMID:16203728 GO_REF:0000096, MGI:MGI:4834177, MGI:MGI:5640951 NCBI chr13:103,818,786...103,920,586
Ensembl chr13:103,818,787...103,920,514
JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) IMP
IBA
ISO
(MGI:MGI:5640942|PMID:23991106)
(MGI:MGI:6201960|PMID:21873635)
UniProtKB
GO_Central
MGI
PMID:21873635, PMID:23991106 GO_REF:0000096, MGI:MGI:4834177, MGI:MGI:5640942, MGI:MGI:6201960 NCBI chr 3:103,856,575...103,912,252
Ensembl chr 3:103,859,795...103,912,247
JBrowse link
G Tnfaip3 tumor necrosis factor, alpha-induced protein 3 IDA (MGI:MGI:3777503|PMID:18342009) BHF-UCL PMID:18342009 MGI:MGI:3777503 NCBI chr10:19,000,910...19,015,410
Ensembl chr10:19,000,910...19,015,657
JBrowse link
nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha IDA (MGI:MGI:3775161|PMID:18261938) MGI PMID:18261938 MGI:MGI:3775161 NCBI chr12:55,489,409...55,492,647
Ensembl chr12:55,489,410...55,492,647
JBrowse link
G Ripk2 receptor (TNFRSF)-interacting serine-threonine kinase 2 IMP (MGI:MGI:2176422|PMID:11894098) MGI PMID:11894098 MGI:MGI:2176422 NCBI chr 4:16,122,732...16,163,678
Ensembl chr 4:16,122,733...16,163,647
JBrowse link
nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Inava innate immunity activator ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 1:136,213,522...136,234,293
Ensembl chr 1:136,213,531...136,234,264
JBrowse link
G Irgm1 immunity-related GTPase family M member 1 ISO (PMID:25891078) UniProtKB PMID:25891078 NCBI chr11:48,865,245...48,871,420
Ensembl chr11:48,861,968...48,871,683
JBrowse link
G Irgm2 immunity-related GTPase family M member 2 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr11:58,214,977...58,222,783
Ensembl chr11:58,199,618...58,222,782
JBrowse link
G Lacc1 laccase domain containing 1 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr14:77,021,739...77,036,929
Ensembl chr14:77,024,200...77,036,904
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha IDA (MGI:MGI:3775161|PMID:18261938) MGI PMID:18261938 MGI:MGI:3775161 NCBI chr12:55,489,409...55,492,647
Ensembl chr12:55,489,410...55,492,647
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 IMP
ISO
(MGI:MGI:5562512|PMID:23892723) MGI PMID:23892723 GO_REF:0000008, MGI:MGI:2154458, MGI:MGI:5562512 NCBI chr 8:88,647,315...88,688,474
Ensembl chr 8:88,647,315...88,688,474
JBrowse link
G Otulin OTU deubiquitinase with linear linkage specificity ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr15:27,597,055...27,630,977
Ensembl chr15:27,542,635...27,630,693
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) ISO MGI GO_REF:0000008, MGI:MGI:2154458 NCBI chr19:5,637,442...5,648,134
Ensembl chr19:5,637,483...5,648,130
JBrowse link
G Ripk2 receptor (TNFRSF)-interacting serine-threonine kinase 2 IMP
ISO
(MGI:MGI:2176422|PMID:11894098) MGI PMID:11894098 GO_REF:0000096, MGI:MGI:2176422, MGI:MGI:4834177 NCBI chr 4:16,122,732...16,163,678
Ensembl chr 4:16,122,733...16,163,647
JBrowse link
positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc15a4 solute carrier family 15, member 4 IMP (MGI:MGI:6278628|PMID:21277849), (MGI:MGI:6450424|PMID:19570976) UniProt PMID:19570976, PMID:21277849 MGI:MGI:6278628, MGI:MGI:6450424 NCBI chr 5:127,594,545...127,633,292
Ensembl chr 5:127,595,664...127,632,897
JBrowse link
G Slc46a2 solute carrier family 46, member 2 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 4:59,905,899...59,915,056
Ensembl chr 4:59,905,126...59,915,056
JBrowse link
G Tlr4 toll-like receptor 4 IDA (MGI:MGI:3775161|PMID:18261938) MGI PMID:18261938 MGI:MGI:3775161 NCBI chr 4:66,827,551...66,846,581
Ensembl chr 4:66,827,584...66,930,284
JBrowse link
positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hspa1a heat shock protein 1A ISO (PMID:24790089) UniProtKB PMID:24790089 NCBI chr17:34,969,359...34,972,156
Ensembl chr17:34,969,190...34,972,156
JBrowse link
G Hspa1b heat shock protein 1B ISO (PMID:24790089) UniProtKB PMID:24790089 NCBI chr17:34,956,429...34,959,238
Ensembl chr17:34,956,436...34,959,238
JBrowse link
G Peli3 pellino 3 IMP (MGI:MGI:5562512|PMID:23892723) MGI PMID:23892723 MGI:MGI:5562512 NCBI chr19:4,929,717...4,943,127
Ensembl chr19:4,929,717...4,943,127
JBrowse link
G Slc15a3 solute carrier family 15, member 3 IDA (MGI:MGI:5571205|PMID:24695226) UniProt PMID:24695226 MGI:MGI:5571205 NCBI chr19:10,842,544...10,857,915
Ensembl chr19:10,839,727...10,859,362
JBrowse link
G Slc15a4 solute carrier family 15, member 4 IDA (MGI:MGI:5571205|PMID:24695226) UniProt PMID:24695226 MGI:MGI:5571205 NCBI chr 5:127,594,545...127,633,292
Ensembl chr 5:127,595,664...127,632,897
JBrowse link
G Tlr4 toll-like receptor 4 IDA (MGI:MGI:3775161|PMID:18261938) MGI PMID:18261938 MGI:MGI:3775161 NCBI chr 4:66,827,551...66,846,581
Ensembl chr 4:66,827,584...66,930,284
JBrowse link
regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Peli3 pellino 3 IMP (MGI:MGI:5562512|PMID:23892723) MGI PMID:23892723 MGI:MGI:5562512 NCBI chr19:4,929,717...4,943,127
Ensembl chr19:4,929,717...4,943,127
JBrowse link
regulation of nucleotide-binding oligomerization domain containing signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc15a2 solute carrier family 15 (H+/peptide transporter), member 2 IMP (MGI:MGI:6192142|PMID:29784761) UniProt PMID:29784761 MGI:MGI:6192142 NCBI chr16:36,750,161...36,785,158
Ensembl chr16:36,750,177...36,784,962
JBrowse link
G Slc15a4 solute carrier family 15, member 4 IMP (MGI:MGI:6192142|PMID:29784761) UniProt PMID:29784761 MGI:MGI:6192142 NCBI chr 5:127,594,545...127,633,292
Ensembl chr 5:127,595,664...127,632,897
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23369
    signaling 6935
      signal transduction 6319
        pattern recognition receptor signaling pathway 163
          cytoplasmic pattern recognition receptor signaling pathway 51
            nucleotide-binding oligomerization domain containing signaling pathway 20
              negative regulation of nucleotide-binding oligomerization domain containing signaling pathway + 3
              nucleotide-binding oligomerization domain containing 1 signaling pathway + 7
              nucleotide-binding oligomerization domain containing 2 signaling pathway + 18
              positive regulation of nucleotide-binding oligomerization domain containing signaling pathway + 7
              regulation of nucleotide-binding oligomerization domain containing signaling pathway + 11
Path 2
Term Annotations click to browse term
  biological_process 23369
    biological regulation 13071
      regulation of biological process 12448
        regulation of cellular process 11895
          signal transduction 6319
            intracellular receptor signaling pathway 230
              cytoplasmic pattern recognition receptor signaling pathway 51
                nucleotide-binding oligomerization domain containing signaling pathway 20
                  negative regulation of nucleotide-binding oligomerization domain containing signaling pathway + 3
                  nucleotide-binding oligomerization domain containing 1 signaling pathway + 7
                  nucleotide-binding oligomerization domain containing 2 signaling pathway + 18
                  positive regulation of nucleotide-binding oligomerization domain containing signaling pathway + 7
                  regulation of nucleotide-binding oligomerization domain containing signaling pathway + 11
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.