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ONTOLOGY REPORT - ANNOTATIONS


Term:nucleotide-binding oligomerization domain containing signaling pathway
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Accession:GO:0070423 term browser browse the term
Definition:Any series of molecular signals generated as a consequence of binding to a nucleotide-binding oligomerization domain containing (NOD) protein.
Synonyms:exact_synonym: NOD signaling pathway;   nucleotide-binding oligomerization domain containing signalling pathway


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negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNFAIP3 TNF alpha induced protein 3 IEA Ensembl GO_REF:0000107 NCBI chr 1:26,474,158...26,489,771
Ensembl chr 1:26,473,938...26,489,822
JBrowse link
negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ERBIN erbb2 interacting protein IEA Ensembl GO_REF:0000107 NCBI chr16:44,415,106...44,533,353
Ensembl chr16:44,225,734...44,533,351
JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:106,692,102...106,758,101
Ensembl chr 4:106,686,604...106,758,099
JBrowse link
G TNFAIP3 TNF alpha induced protein 3 IEA Ensembl GO_REF:0000107 NCBI chr 1:26,474,158...26,489,771
Ensembl chr 1:26,473,938...26,489,822
JBrowse link
nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NFKBIA NFKB inhibitor alpha IEA Ensembl GO_REF:0000107 NCBI chr 7:64,508,119...64,510,754
Ensembl chr 7:64,508,016...64,558,057
JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 IEA Ensembl GO_REF:0000107 NCBI chr 4:47,026,558...47,075,133
Ensembl chr 4:47,027,092...47,074,725
JBrowse link
nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G INAVA innate immunity activator IEA Ensembl GO_REF:0000107 NCBI chr10:23,392,202...23,414,318
Ensembl chr10:23,392,298...23,412,712
JBrowse link
G LACC1 laccase domain containing 1 ISO (PMID:31875558) UniProt PMID:31875558 NCBI chr11:23,143,708...23,159,790 JBrowse link
G NFKBIA NFKB inhibitor alpha IEA Ensembl GO_REF:0000107 NCBI chr 7:64,508,119...64,510,754
Ensembl chr 7:64,508,016...64,558,057
JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 IEA Ensembl GO_REF:0000107 NCBI chr 6:34,132,127...34,167,446
Ensembl chr 6:34,130,938...34,177,534
JBrowse link
G OTULIN OTU deubiquitinase with linear linkage specificity IEA Ensembl GO_REF:0000107 NCBI chr16:4,063,037...4,097,112
Ensembl chr16:4,063,071...4,097,095
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit IEA Ensembl GO_REF:0000107 NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,471
JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 IEA Ensembl GO_REF:0000107 NCBI chr 4:47,026,558...47,075,133
Ensembl chr 4:47,027,092...47,074,725
JBrowse link
positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC15A4 solute carrier family 15 member 4 IEA Ensembl GO_REF:0000107 NCBI chr14:26,122,362...26,154,414
Ensembl chr14:26,122,363...26,154,786
JBrowse link
G SLC46A2 solute carrier family 46 member 2 IEA Ensembl GO_REF:0000107 NCBI chr 1:253,559,545...253,571,015
Ensembl chr 1:253,556,919...253,570,113
JBrowse link
G TLR4 toll like receptor 4 IEA Ensembl GO_REF:0000107 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,059,004
JBrowse link
positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PELI3 pellino E3 ubiquitin protein ligase family member 3 ISO (MGI:MGI:5562512|PMID:23892723) MGI PMID:23892723 MGI:MGI:5562512 NCBI chr 2:5,950,552...5,959,786
Ensembl chr 2:5,947,962...5,959,731
JBrowse link
G SLC15A3 solute carrier family 15 member 3 IEA Ensembl GO_REF:0000107 NCBI chr 2:10,799,927...10,814,363
Ensembl chr 2:10,800,547...10,816,519
JBrowse link
G SLC15A4 solute carrier family 15 member 4 IEA Ensembl GO_REF:0000107 NCBI chr14:26,122,362...26,154,414
Ensembl chr14:26,122,363...26,154,786
JBrowse link
G TLR4 toll like receptor 4 IEA Ensembl GO_REF:0000107 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,059,004
JBrowse link
regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PELI3 pellino E3 ubiquitin protein ligase family member 3 ISO (MGI:MGI:5562512|PMID:23892723) MGI PMID:23892723 MGI:MGI:5562512 NCBI chr 2:5,950,552...5,959,786
Ensembl chr 2:5,947,962...5,959,731
JBrowse link
regulation of nucleotide-binding oligomerization domain containing signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC15A2 solute carrier family 15 member 2 ISO (MGI:MGI:6192142|PMID:29784761) UniProt PMID:29784761 MGI:MGI:6192142 NCBI chr13:138,595,942...138,634,473
Ensembl chr13:138,595,954...138,681,573
JBrowse link
G SLC15A4 solute carrier family 15 member 4 ISO (MGI:MGI:6192142|PMID:29784761) UniProt PMID:29784761 MGI:MGI:6192142 NCBI chr14:26,122,362...26,154,414
Ensembl chr14:26,122,363...26,154,786
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16524
    signaling 6450
      signal transduction 5920
        pattern recognition receptor signaling pathway 152
          cytoplasmic pattern recognition receptor signaling pathway 47
            nucleotide-binding oligomerization domain containing signaling pathway 16
              negative regulation of nucleotide-binding oligomerization domain containing signaling pathway + 3
              nucleotide-binding oligomerization domain containing 1 signaling pathway + 7
              nucleotide-binding oligomerization domain containing 2 signaling pathway + 14
              positive regulation of nucleotide-binding oligomerization domain containing signaling pathway + 5
              regulation of nucleotide-binding oligomerization domain containing signaling pathway + 9
Path 2
Term Annotations click to browse term
  biological_process 16524
    biological regulation 11991
      regulation of biological process 11411
        regulation of cellular process 10961
          signal transduction 5920
            intracellular receptor signaling pathway 245
              cytoplasmic pattern recognition receptor signaling pathway 47
                nucleotide-binding oligomerization domain containing signaling pathway 16
                  negative regulation of nucleotide-binding oligomerization domain containing signaling pathway + 3
                  nucleotide-binding oligomerization domain containing 1 signaling pathway + 7
                  nucleotide-binding oligomerization domain containing 2 signaling pathway + 14
                  positive regulation of nucleotide-binding oligomerization domain containing signaling pathway + 5
                  regulation of nucleotide-binding oligomerization domain containing signaling pathway + 9
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.