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ONTOLOGY REPORT - ANNOTATIONS


Term:elongin complex
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Accession:GO:0070449 term browser browse the term
Definition:A transcription elongation factor complex that suppresses RNA polymerase II pausing, and may act by promoting proper alignment of the 3'-end of nascent transcripts with the polymerase catalytic site. Consists of a transcriptionally active Elongin A subunit (abut 100 kDa)and two smaller Elongin B (about 18 kDa) and Elongin C (about 15 kDa)subunits.
Comment:See also the cellular component terms 'cyclin-dependent protein kinase activating kinase holoenzyme complex ; GO:0019907' and 'DNA-directed RNA polymerase II, holoenzyme ; GO:0016591'.
Synonyms:exact_synonym: elongin (SIII) complex;   transcription elongation factor SIII complex


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elongin complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Eloa elongin A JBrowse link NW_004955452 3,668,868 3,681,506 RGD:9068941
G Elob elongin B JBrowse link NW_004955442 14,498,666 14,501,895 RGD:9068941
G Eloc elongin C JBrowse link NW_004955444 6,400,721 6,415,881 RGD:9068941

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Term Annotations click to browse term
  cellular_component 15269
    protein-containing complex 4761
      transcription elongation factor complex 50
        elongin complex 3
Path 2
Term Annotations click to browse term
  cellular_component 15269
    cellular anatomical entity 15145
      organelle 11904
        intracellular organelle 11016
          intracellular membrane-bounded organelle 9502
            nucleus 6476
              nuclear lumen 4366
                nucleoplasm 3705
                  transcription elongation factor complex 50
                    elongin complex 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.