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ONTOLOGY REPORT - ANNOTATIONS


Term:thrombin-activated receptor signaling pathway
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Accession:GO:0070493 term browser browse the term
Definition:The series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands.
Synonyms:exact_synonym: thrombin receptor signaling pathway;   thrombin receptor signalling pathway


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thrombin-activated receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dgkq diacylglycerol kinase, theta ISO (PMID:15632189) RGD PMID:15632189 NCBI chr14:2,069,409...2,083,370
Ensembl chr14:2,069,409...2,083,370
JBrowse link
G F2r coagulation factor II (thrombin) receptor ISS
ISO
IEA
GO_REF:0000024
MGI:88380 (MGI:3810206|PMID:18398001)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:18398001 GO_REF:0000024, GO_REF:0000107, MGI:3810206 NCBI chr 2:26,118,760...26,135,340
Ensembl chr 2:26,118,760...26,135,340
JBrowse link
G F2rl1 F2R like trypsin receptor 1 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:25,222,324...25,235,275
Ensembl chr 2:25,222,328...25,235,275
JBrowse link
G F2rl2 coagulation factor II (thrombin) receptor-like 2 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:26,240,385...26,245,533
Ensembl chr 2:26,240,385...26,245,533
JBrowse link
G F2rl3 F2R like thrombin or trypsin receptor 3 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr16:18,817,797...18,819,790
Ensembl chr16:18,814,622...18,819,833
JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase IEP PMID:19383433 UniProt PMID:19383433 RGD:8553438 NCBI chr16:37,457,134...37,495,758
Ensembl chr16:37,457,135...37,495,758
JBrowse link
G Iqgap2 IQ motif containing GTPase activating protein 2 ISO (PMID:12515716) RGD PMID:12515716 NCBI chr 2:26,161,628...26,439,067
Ensembl chr 2:26,167,199...26,438,790
JBrowse link
G Plek pleckstrin ISO (PMID:7782310)
(MGI:3844782|PMID:19190246)
RGD PMID:7782310, PMID:19190246 MGI:3844782 NCBI chr14:100,151,518...100,184,192
Ensembl chr14:100,151,210...100,217,913
JBrowse link
negative regulation of thrombin-activated receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Met MET proto-oncogene, receptor tyrosine kinase IEA
ISO
GO_REF:0000107
(PMID:25198505)
Ensembl
RGD
PMID:25198505 GO_REF:0000107 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665
JBrowse link
G Snca synuclein alpha ISO (PMID:12239163) RGD PMID:12239163 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
G Stmn1 stathmin 1 ISO (PMID:25198505) RGD PMID:25198505 NCBI chr 5:152,680,412...152,686,807
Ensembl chr 5:152,680,407...152,686,806
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    signaling 7579
      signal transduction 7010
        G protein-coupled receptor signaling pathway 2509
          thrombin-activated receptor signaling pathway 11
            negative regulation of thrombin-activated receptor signaling pathway 3
            positive regulation of thrombin-activated receptor signaling pathway 0
            regulation of thrombin-activated receptor signaling pathway + 3
Path 2
Term Annotations click to browse term
  biological_process 20020
    biological regulation 13769
      regulation of biological process 13071
        regulation of cellular process 12556
          signal transduction 7010
            G protein-coupled receptor signaling pathway 2509
              thrombin-activated receptor signaling pathway 11
                negative regulation of thrombin-activated receptor signaling pathway 3
                positive regulation of thrombin-activated receptor signaling pathway 0
                regulation of thrombin-activated receptor signaling pathway + 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.