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ONTOLOGY REPORT - ANNOTATIONS


Term:BRCA1-A complex
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Accession:GO:0070531 term browser browse the term
Definition:A protein complex that contains the BRCA1-BARD1 heterodimer, RAP80/UIMC1, BRCC3/BRCC36, BRE/BRCC45, FAM175A/CCDC98/Abraxas and MERIT40/NBA1, and specifically recognizes and binds K63-linked polyubiquitin chains present on histone H2A and H2AX at DNA damage sites.


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BRCA1-A complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abraxas1 abraxas 1, BRCA1 A complex subunit JBrowse link 14 10,424,674 10,439,010 RGD:1600115
RGD:1624291
G Babam1 BRISC and BRCA1 A complex member 1 JBrowse link 16 19,792,720 19,798,886 RGD:1600115
RGD:1624291
G Babam2 BRISC and BRCA1 A complex member 2 JBrowse link 6 25,666,654 26,135,888 RGD:1600115
RGD:1624291
G Bard1 BRCA1 associated RING domain 1 JBrowse link 9 78,297,723 78,368,777 RGD:1600115
RGD:1624291
G Brca1 BRCA1, DNA repair associated JBrowse link 10 89,394,821 89,455,093 RGD:1600115
RGD:13792537
RGD:1624291
G Brcc3 BRCA1/BRCA2-containing complex, subunit 3 JBrowse link 9 9,863,380 9,865,920 RGD:1600115
RGD:1624291
RGD:13792537
G Uimc1 ubiquitin interaction motif containing 1 JBrowse link 17 10,061,915 10,130,921 RGD:1600115
RGD:13792537
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19843
    protein-containing complex 5779
      BRCA1-A complex 7
Path 2
Term Annotations click to browse term
  cellular_component 19843
    cellular anatomical entity 19457
      organelle 12557
        membrane-bounded organelle 10879
          intracellular membrane-bounded organelle 9976
            nucleus 6783
              BRCA1-A complex 7
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.