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ONTOLOGY REPORT - ANNOTATIONS


Term:protein K63-linked deubiquitination
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Accession:GO:0070536 term browser browse the term
Definition:A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a protein.


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protein K63-linked deubiquitination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abraxas1 abraxas 1, BRCA1 A complex subunit JBrowse link 14 10,424,674 10,439,010 RGD:13792537
G Abraxas2 abraxas 2, BRISC complex subunit JBrowse link 1 204,861,768 204,887,344 RGD:1624291
RGD:13792537
G Atxn3 ataxin 3 JBrowse link 6 125,817,420 125,853,461 RGD:1624291
RGD:1600115
G Babam1 BRISC and BRCA1 A complex member 1 JBrowse link 16 19,792,720 19,798,886 RGD:1624291
RGD:1600115
G Brcc3 BRCA1/BRCA2-containing complex, subunit 3 JBrowse link 9 9,863,380 9,865,920 RGD:1600115
RGD:13792537
RGD:1624291
G Cyld CYLD lysine 63 deubiquitinase JBrowse link 19 19,264,984 19,323,817 RGD:1600115
RGD:13792537
RGD:1624291
G Desi2 desumoylating isopeptidase 2 JBrowse link 13 96,111,800 96,156,693 RGD:1600115
G LOC100910107 ubiquitin carboxyl-terminal hydrolase DUB-1-like JBrowse link 1 169,720,247 169,721,788 RGD:1624291
G Otub2 OTU deubiquitinase, ubiquitin aldehyde binding 2 JBrowse link 6 127,282,445 127,301,086 RGD:1624291
RGD:13792537
G Otud1 OTU deubiquitinase 1 JBrowse link 17 86,406,643 86,410,670 RGD:1624291
RGD:13792537
G Otud4 OTU deubiquitinase 4 JBrowse link 19 31,895,753 31,942,509 RGD:1624291
G Otud5 OTU deubiquitinase 5 JBrowse link X 15,471,212 15,504,372 RGD:1600115
RGD:1624291
G Otud7a OTU deubiquitinase 7A JBrowse link 1 124,311,873 124,655,437 RGD:13792537
G Otud7b OTU deubiquitinase 7B JBrowse link 2 198,231,353 198,302,220 RGD:1624291
RGD:13792537
RGD:1600115
G Psmd14 proteasome 26S subunit, non-ATPase 14 JBrowse link 3 47,578,449 47,673,330 RGD:1624291
G Shmt2 serine hydroxymethyltransferase 2 JBrowse link 7 70,824,718 70,829,822 RGD:1624291
G Spata2 spermatogenesis associated 2 JBrowse link 3 164,229,211 164,239,483 RGD:1600115
RGD:13792537
RGD:1624291
G Stambp Stam binding protein JBrowse link 4 115,249,343 115,277,340 RGD:13792537
G Stambpl1 STAM binding protein-like 1 JBrowse link 1 252,490,125 252,536,113 RGD:13792537
G Tnfaip3 TNF alpha induced protein 3 JBrowse link 1 14,401,103 14,416,369 RGD:1624291
G Usp13 ubiquitin specific peptidase 13 JBrowse link 2 119,197,153 119,317,507 RGD:1624291
G Usp20 ubiquitin specific peptidase 20 JBrowse link 3 9,822,586 9,856,057 RGD:1624291
G Usp25 ubiquitin specific peptidase 25 JBrowse link 11 15,436,080 15,558,646 RGD:1624291
G Usp27x ubiquitin specific peptidase 27, X-linked JBrowse link X 15,987,964 15,991,149 RGD:1624291
G Usp33 ubiquitin specific peptidase 33 JBrowse link 2 257,567,179 257,602,817 RGD:1624291
G Usp50 ubiquitin specific peptidase 50 JBrowse link 3 119,225,055 119,247,442 RGD:13792537
G Usp7 ubiquitin specific peptidase 7 JBrowse link 10 6,930,462 7,019,910 RGD:1600115
RGD:1624291
G Usp8 ubiquitin specific peptidase 8 JBrowse link 3 119,173,818 119,222,499 RGD:1624291
RGD:13792537
G Yod1 YOD1 deubiquitinase JBrowse link 13 47,441,296 47,443,013 RGD:1600115
RGD:1624291
G Zranb1 zinc finger RANBP2-type containing 1 JBrowse link 1 204,938,444 205,000,163 RGD:1624291
histone H2A K63-linked deubiquitination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Brcc3 BRCA1/BRCA2-containing complex, subunit 3 JBrowse link 9 9,863,380 9,865,920 RGD:1600115
RGD:13792537
RGD:1624291
G Uimc1 ubiquitin interaction motif containing 1 JBrowse link 17 10,061,915 10,130,921 RGD:1624291
RGD:1600115
RGD:13792537
G Usp16 ubiquitin specific peptidase 16 JBrowse link 11 27,101,213 27,130,345 RGD:1624291
RGD:1600115
positive regulation of Lys63-specific deubiquitinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Vcp valosin-containing protein JBrowse link 5 58,426,548 58,445,953 RGD:1624291
positive regulation of protein K63-linked deubiquitination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nop53 NOP53 ribosome biogenesis factor JBrowse link 1 77,836,522 77,843,991 RGD:1624291
G Vcp valosin-containing protein JBrowse link 5 58,426,548 58,445,953 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    metabolic process 12096
      primary metabolic process 10749
        protein metabolic process 6185
          proteolysis 1882
            protein modification by small protein removal 152
              protein deubiquitination 121
                protein K63-linked deubiquitination 34
                  histone H2A K63-linked deubiquitination 3
                  negative regulation of protein K63-linked deubiquitination 0
                  positive regulation of protein K63-linked deubiquitination + 2
                  regulation of protein K63-linked deubiquitination + 2
Path 2
Term Annotations click to browse term
  biological_process 19858
    metabolic process 12096
      organic substance metabolic process 11494
        macromolecule metabolic process 9943
          macromolecule modification 4106
            protein modification process 3901
              cellular protein modification process 3901
                protein modification by small protein conjugation or removal 934
                  protein modification by small protein removal 152
                    protein deubiquitination 121
                      protein K63-linked deubiquitination 34
                        histone H2A K63-linked deubiquitination 3
                        negative regulation of protein K63-linked deubiquitination 0
                        positive regulation of protein K63-linked deubiquitination + 2
                        regulation of protein K63-linked deubiquitination + 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.