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ONTOLOGY REPORT - ANNOTATIONS


Term:protein K63-linked deubiquitination
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Accession:GO:0070536 term browser browse the term
Definition:A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a protein.


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protein K63-linked deubiquitination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abraxas2 abraxas 2, BRISC complex subunit JBrowse link NW_004955477 2,782,604 2,811,452 RGD:9068941
G Atxn3 ataxin 3 JBrowse link NW_004955438 14,405,415 14,443,457 RGD:9068941
G Babam1 BRISC and BRCA1 A complex member 1 JBrowse link NW_004955524 939,250 944,457 RGD:9068941
G Brcc3 BRCA1/BRCA2-containing complex subunit 3 JBrowse link NW_004955594 551,407 613,772 RGD:9068941
G Cyld CYLD lysine 63 deubiquitinase JBrowse link NW_004955433 8,788,867 8,845,925 RGD:9068941
G Otub2 OTU deubiquitinase, ubiquitin aldehyde binding 2 JBrowse link NW_004955438 16,079,859 16,096,686 RGD:9068941
G Otud1 OTU deubiquitinase 1 JBrowse link NW_004955429 5,588,333 5,590,220 RGD:9068941
G Otud4 OTU deubiquitinase 4 JBrowse link NW_004955428 1,062,998 1,108,711 RGD:9068941
G Otud5 OTU deubiquitinase 5 JBrowse link NW_004955543 452,172 484,564 RGD:9068941
G Otud7b OTU deubiquitinase 7B JBrowse link NW_004955413 758,098 812,605 RGD:9068941
G Psmd14 proteasome 26S subunit, non-ATPase 14 JBrowse link NW_004955449 12,306,026 12,400,908 RGD:9068941
G Shmt2 serine hydroxymethyltransferase 2 JBrowse link NW_004955458 4,957,614 4,962,691 RGD:9068941
G Spata2 spermatogenesis associated 2 JBrowse link NW_004955445 8,281,280 8,292,951 RGD:9068941
G Tnfaip3 TNF alpha induced protein 3 JBrowse link NW_004955436 21,566,591 21,581,551 RGD:9068941
G Usp13 ubiquitin specific peptidase 13 JBrowse link NW_004955420 8,835,858 8,919,837 RGD:9068941
G Usp20 ubiquitin specific peptidase 20 JBrowse link NW_004955513 43,601 70,714 RGD:9068941
G Usp25 ubiquitin specific peptidase 25 JBrowse link NW_004955407 17,429,299 17,572,138 RGD:9068941
G Usp27x ubiquitin specific peptidase 27 X-linked JBrowse link NW_004955543 1,023,931 1,027,048 RGD:9068941
G Usp33 ubiquitin specific peptidase 33 JBrowse link NW_004955423 15,424,349 15,469,344 RGD:9068941
G Usp7 ubiquitin specific peptidase 7 JBrowse link NW_004955442 9,316,022 9,355,751 RGD:9068941
G Usp8 ubiquitin specific peptidase 8 JBrowse link NW_004955409 3,839,308 3,903,595 RGD:9068941
G Zranb1 zinc finger RANBP2-type containing 1 JBrowse link NW_004955477 2,864,737 2,922,069 RGD:9068941
histone H2A K63-linked deubiquitination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Brcc3 BRCA1/BRCA2-containing complex subunit 3 JBrowse link NW_004955594 551,407 613,772 RGD:9068941
G Uimc1 ubiquitin interaction motif containing 1 JBrowse link NW_004955408 29,154,373 29,274,817 RGD:9068941
G Usp16 ubiquitin specific peptidase 16 JBrowse link NW_004955407 28,375,246 28,413,279 RGD:9068941
positive regulation of Lys63-specific deubiquitinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Vcp valosin containing protein JBrowse link NW_004955472 1,111,649 1,124,076 RGD:9068941
positive regulation of protein K63-linked deubiquitination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nop53 NOP53 ribosome biogenesis factor JBrowse link NW_004955574 1,505,997 1,514,680 RGD:9068941
G Vcp valosin containing protein JBrowse link NW_004955472 1,111,649 1,124,076 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11825
    metabolic process 7568
      primary metabolic process 6710
        protein metabolic process 3829
          proteolysis 1048
            protein modification by small protein removal 105
              protein deubiquitination 91
                protein K63-linked deubiquitination 26
                  histone H2A K63-linked deubiquitination 3
                  negative regulation of protein K63-linked deubiquitination 0
                  positive regulation of protein K63-linked deubiquitination + 2
                  regulation of protein K63-linked deubiquitination + 2
Path 2
Term Annotations click to browse term
  biological_process 11825
    metabolic process 7568
      organic substance metabolic process 7272
        macromolecule metabolic process 6316
          macromolecule modification 2976
            protein modification process 2850
              cellular protein modification process 2850
                protein modification by small protein conjugation or removal 638
                  protein modification by small protein removal 105
                    protein deubiquitination 91
                      protein K63-linked deubiquitination 26
                        histone H2A K63-linked deubiquitination 3
                        negative regulation of protein K63-linked deubiquitination 0
                        positive regulation of protein K63-linked deubiquitination + 2
                        regulation of protein K63-linked deubiquitination + 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.