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ONTOLOGY REPORT - ANNOTATIONS


Term:histone H2A K63-linked deubiquitination
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Accession:GO:0070537 term browser browse the term
Definition:A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a lysine residue in histone H2A or the variant H2AX.


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histone H2A K63-linked deubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRCC3 BRCA1/BRCA2-containing complex subunit 3 ISO (PMID:19202061)
(PMID:19261746)
UniProtKB PMID:19202061, PMID:19261746 NCBI chr  X:144,550,320...144,592,795 JBrowse link
G UIMC1 ubiquitin interaction motif containing 1 ISO (PMID:19202061) UniProtKB PMID:19202061 NCBI chr 5:172,205,958...172,321,758
Ensembl chr 5:179,271,577...179,374,229
JBrowse link
G USP16 ubiquitin specific peptidase 16 ISO (PMID:20550933) UniProtKB PMID:20550933 NCBI chr21:15,455,805...15,487,853
Ensembl chr21:28,843,749...28,876,267
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12524
    metabolic process 7962
      primary metabolic process 7030
        protein metabolic process 3992
          proteolysis 1102
            protein modification by small protein removal 111
              protein deubiquitination 97
                protein K63-linked deubiquitination 27
                  histone H2A K63-linked deubiquitination 3
Path 2
Term Annotations click to browse term
  biological_process 12524
    metabolic process 7962
      organic substance metabolic process 7650
        macromolecule metabolic process 6615
          protein metabolic process 3992
            protein modification process 2964
              cellular protein modification process 2964
                protein modification by small protein conjugation or removal 663
                  protein modification by small protein removal 111
                    protein deubiquitination 97
                      histone deubiquitination 23
                        histone H2A K63-linked deubiquitination 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.