ONTOLOGY REPORT - ANNOTATIONS


Term:leukocyte proliferation
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Accession:GO:0070661 term browser browse the term
Definition:The expansion of a leukocyte population by cell division.


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leukocyte proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G F2RL1 F2R like trypsin receptor 1 JBrowse link 5 39,008,288 39,024,188 RGD:9068941
activated T cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link 9 130,482,852 130,652,941 RGD:9068941
G BTN3A1 butyrophilin subfamily 3 member A1 JBrowse link 6 26,892,960 26,905,915 RGD:9068941
G CADM1 cell adhesion molecule 1 JBrowse link 11 113,950,291 114,280,453 RGD:9068941
G CRTAM cytotoxic and regulatory T cell molecule JBrowse link 11 121,591,738 121,625,744 RGD:9068941
G EPHB6 EPH receptor B6 JBrowse link 7 147,337,558 147,353,575 RGD:9068941
G FYN FYN proto-oncogene, Src family tyrosine kinase JBrowse link 6 113,545,944 113,732,893 RGD:9068941
G SATB1 SATB homeobox 1 JBrowse link 3 18,602,204 18,700,696 RGD:9068941
alpha-beta T cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DOCK2 dedicator of cytokinesis 2 JBrowse link 5 171,761,545 172,206,762 RGD:9068941
B cell homeostatic proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BAX BCL2 associated X, apoptosis regulator JBrowse link 19 54,793,594 54,800,466 RGD:9068941
G RAG2 recombination activating 2 JBrowse link 11 36,431,067 36,437,390 RGD:9068941
B cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATAD5 ATPase family AAA domain containing 5 JBrowse link 17 25,435,787 25,496,752 RGD:9068941
G BCL2 BCL2 apoptosis regulator JBrowse link 18 59,797,184 59,993,298 RGD:9068941
G CARD11 caspase recruitment domain family member 11 JBrowse link 7 3,258,736 3,395,626 RGD:9068941
G CD40 CD40 molecule JBrowse link 20 43,541,619 43,552,994 RGD:9068941
G CD40LG CD40 ligand JBrowse link X 136,042,849 136,055,158 RGD:9068941
G CD79A CD79a molecule JBrowse link 19 47,270,377 47,274,711 RGD:9068941
G CR2 complement C3d receptor 2 JBrowse link 1 187,330,483 187,366,069 RGD:9068941
G CTPS1 CTP synthase 1 JBrowse link 1 41,592,069 41,624,455 RGD:9068941
G HSPD1 heat shock protein family D (Hsp60) member 1 JBrowse link 2B 202,623,497 202,637,045 RGD:9068941
G IFNA2 interferon alpha 2 JBrowse link 9 21,862,557 21,863,690 RGD:9068941
G IFNA21 interferon alpha 21 JBrowse link 9 21,629,421 21,630,428 RGD:9068941
G IFNA6 interferon alpha 6 JBrowse link 9 21,828,719 21,829,288 RGD:9068941
G IFNA8 interferon alpha 8 JBrowse link 9 21,887,420 21,888,459 RGD:9068941
G IFNB1 interferon beta 1 JBrowse link 9 21,540,849 21,541,695 RGD:9068941
G IFNE interferon epsilon JBrowse link 9 21,959,043 21,960,511 RGD:9068941
G IFNK interferon kappa JBrowse link 9 27,978,446 27,979,069 RGD:9068941
G IFNW1 interferon omega 1 JBrowse link 9 21,604,387 21,605,643 RGD:9068941
G IL10 interleukin 10 JBrowse link 1 186,648,289 186,653,155 RGD:9068941
G IL7R interleukin 7 receptor JBrowse link 5 79,769,859 79,792,566 RGD:9068941
G LEF1 lymphoid enhancer binding factor 1 JBrowse link 4 111,125,312 111,245,980 RGD:9068941
G MEF2C myocyte enhancer factor 2C JBrowse link 5 26,620,837 26,786,426 RGD:9068941
G MS4A1 membrane spanning 4-domains A1 JBrowse link 11 59,134,579 59,148,832 RGD:9068941
G PRKCD protein kinase C delta JBrowse link 3 54,330,328 54,357,910 RGD:9068941
G PTPRC protein tyrosine phosphatase receptor type C JBrowse link 1 178,555,803 178,674,089 RGD:9068941
B cell proliferation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link 9 130,482,852 130,652,941 RGD:9068941
G CD180 CD180 molecule JBrowse link 5 48,364,874 48,381,700 RGD:9068941
G CD19 CD19 molecule JBrowse link 16 29,320,734 29,327,860 RGD:9068941
G GAPT GRB2 binding adaptor protein, transmembrane JBrowse link 5 57,144,459 57,145,229 RGD:9068941
G PLCL2 phospholipase C like 2 JBrowse link 3 17,154,506 17,351,287 RGD:9068941
G TLR4 toll like receptor 4 JBrowse link 9 117,180,250 117,193,510 RGD:9068941
dendritic cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AZI2 5-azacytidine induced 2 JBrowse link 3 28,534,050 28,560,944 RGD:9068941
G TBK1 TANK binding kinase 1 JBrowse link 12 24,919,412 24,968,587 RGD:9068941
immature T cell proliferation in thymus term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G WNT4 Wnt family member 4 JBrowse link 1 22,252,344 22,264,858 RGD:9068941
lymphocyte proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FLT3 fms related tyrosine kinase 3 JBrowse link 13 27,627,178 27,694,863 RGD:9068941
G HELLS helicase, lymphoid specific JBrowse link 10 94,790,137 94,847,209 RGD:9068941
G HPRT1 hypoxanthine phosphoribosyltransferase 1 JBrowse link X 133,908,233 133,948,197 RGD:9068941
G IMPDH1 inosine monophosphate dehydrogenase 1 JBrowse link 7 133,036,328 133,053,496 RGD:9068941
G IMPDH2 inosine monophosphate dehydrogenase 2 JBrowse link 3 50,030,291 50,035,676 RGD:9068941
G PURA purine rich element binding protein A JBrowse link 5 141,599,010 141,604,016 RGD:9068941
mast cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G KIT KIT proto-oncogene, receptor tyrosine kinase JBrowse link 4 75,761,946 75,844,473 RGD:9068941
memory T cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DOCK8 dedicator of cytokinesis 8 JBrowse link 9 201,156 446,910 RGD:9068941
microglial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CLU clusterin JBrowse link 8 24,070,053 24,086,934 RGD:9068941
G CSF1 colony stimulating factor 1 JBrowse link 1 127,764,916 127,864,188 RGD:9068941
G CSF1R colony stimulating factor 1 receptor JBrowse link 5 151,483,948 151,543,128 RGD:9068941
G CX3CL1 C-X3-C motif chemokine ligand 1 JBrowse link 16 56,779,065 56,791,760 RGD:9068941
G IL33 interleukin 33 JBrowse link 9 6,208,479 6,250,433 RGD:9068941
G IL34 interleukin 34 JBrowse link 16 70,414,135 70,494,693 RGD:9068941
mononuclear cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TGFB1 transforming growth factor beta 1 JBrowse link 19 46,831,659 46,852,973 RGD:9068941
natural killer cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ELF4 E74 like ETS transcription factor 4 JBrowse link X 129,486,097 129,531,764 RGD:9068941
negative regulation of activated T cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARG1 arginase 1 JBrowse link 6 133,479,966 133,491,162 RGD:9068941
G BTN2A2 butyrophilin subfamily 2 member A2 JBrowse link 6 26,873,828 26,893,135 RGD:9068941
G CASP3 caspase 3 JBrowse link 4 189,018,422 189,040,217 RGD:9068941
G CD274 CD274 molecule JBrowse link 9 5,454,391 5,474,452 RGD:9068941
G FOXP3 forkhead box P3 JBrowse link X 49,402,652 49,417,029 RGD:9068941
G LRRC32 leucine rich repeat containing 32 JBrowse link 11 75,354,997 75,368,187 RGD:9068941
G PDCD1LG2 programmed cell death 1 ligand 2 JBrowse link 9 5,514,449 5,575,660 RGD:9068941
G PRKAR1A protein kinase cAMP-dependent type I regulatory subunit alpha JBrowse link 17 67,838,484 67,859,610 RGD:9068941
G PRNP prion protein JBrowse link 20 4,523,141 4,525,522 RGD:9068941
G RC3H1 ring finger and CCCH-type domains 1 JBrowse link 1 153,153,048 153,213,402 RGD:9068941
negative regulation of alpha-beta T cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ITCH itchy E3 ubiquitin protein ligase JBrowse link 20 31,822,496 31,971,945 RGD:9068941
G TNFRSF14 TNF receptor superfamily member 14 JBrowse link 1 2,427,421 2,435,615 RGD:9068941
negative regulation of B cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATM ATM serine/threonine kinase JBrowse link 11 106,584,228 106,728,457 RGD:9068941
G BTK Bruton tyrosine kinase JBrowse link X 100,684,017 100,720,868 RGD:9068941
G CASP3 caspase 3 JBrowse link 4 189,018,422 189,040,217 RGD:9068941
G CD300A CD300a molecule JBrowse link 17 73,963,312 73,984,547 RGD:9068941
G CDKN2A cyclin dependent kinase inhibitor 2A JBrowse link 9 22,420,748 22,447,243 RGD:9068941
G CTLA4 cytotoxic T-lymphocyte associated protein 4 JBrowse link 2B 209,239,417 209,244,498 RGD:9068941
G IL10 interleukin 10 JBrowse link 1 186,648,289 186,653,155 RGD:9068941
G INPP5D inositol polyphosphate-5-phosphatase D JBrowse link 2B 239,201,762 239,350,190 RGD:9068941
G LOC100984838 low affinity immunoglobulin gamma Fc region receptor II-b JBrowse link 1 140,882,104 140,890,036 RGD:9068941
G LYN LYN proto-oncogene, Src family tyrosine kinase JBrowse link 8 49,755,745 49,825,287 RGD:9068941
G MNDA myeloid cell nuclear differentiation antigen JBrowse link 1 137,981,896 137,999,850 RGD:9068941
G PAWR pro-apoptotic WT1 regulator JBrowse link 12 79,964,693 80,071,088 RGD:9068941
G PKN1 protein kinase N1 JBrowse link 19 14,838,478 14,879,205 RGD:9068941
G RC3H1 ring finger and CCCH-type domains 1 JBrowse link 1 153,153,048 153,213,402 RGD:9068941
G TNFRSF13B TNF receptor superfamily member 13B JBrowse link 17 39,252,858 39,286,007 RGD:9068941
G TNFRSF21 TNF receptor superfamily member 21 JBrowse link 6 48,079,749 48,158,356 RGD:9068941
G TYROBP TYRO protein tyrosine kinase binding protein JBrowse link 19 41,570,674 41,575,226 RGD:9068941
negative regulation of CD4-positive, alpha-beta T cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARG2 arginase 2 JBrowse link 14 67,075,941 67,109,962 RGD:9068941
G CD274 CD274 molecule JBrowse link 9 5,454,391 5,474,452 RGD:9068941
G TWSG1 twisted gastrulation BMP signaling modulator 1 JBrowse link 18 7,164,091 7,229,271 RGD:9068941
G VSIR V-set immunoregulatory receptor JBrowse link 10 70,742,062 70,767,613 RGD:9068941
negative regulation of CD8-positive, alpha-beta T cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G VSIR V-set immunoregulatory receptor JBrowse link 10 70,742,062 70,767,613 RGD:9068941
negative regulation of immature T cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GNRH1 gonadotropin releasing hormone 1 JBrowse link 8 21,609,407 21,616,521 RGD:9068941
negative regulation of immature T cell proliferation in thymus term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BMP4 bone morphogenetic protein 4 JBrowse link 14 52,821,872 52,828,781 RGD:9068941
G CDKN2A cyclin dependent kinase inhibitor 2A JBrowse link 9 22,420,748 22,447,243 RGD:9068941
G ERBB2 erb-b2 receptor tyrosine kinase 2 JBrowse link 17 17,777,434 17,817,735 RGD:9068941
G IHH Indian hedgehog signaling molecule JBrowse link 2B 224,905,488 224,917,887 RGD:9068941
G TMEM131L transmembrane 131 like JBrowse link 4 157,630,958 157,802,132 RGD:9068941
negative regulation of leukocyte proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CCL8 C-C motif chemokine ligand 8 JBrowse link 17 22,761,570 22,763,933 RGD:9068941
G GSTP1 glutathione S-transferase pi 1 JBrowse link 11 66,253,421 66,256,472 RGD:9068941
negative regulation of lymphocyte proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GAL galanin and GMAP prepropeptide JBrowse link 11 67,075,104 67,081,696 RGD:9068941
G IL2 interleukin 2 JBrowse link 4 125,782,563 125,787,819 RGD:9068941
G LST1 leukocyte specific transcript 1 JBrowse link 6 32,137,214 32,139,995 RGD:9068941
G SOX11 SRY-box 11 JBrowse link 2A 5,840,399 5,841,762 RGD:9068941
negative regulation of mast cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 JBrowse link 6 133,544,650 133,638,009 RGD:9068941
G LYN LYN proto-oncogene, Src family tyrosine kinase JBrowse link 8 49,755,745 49,825,287 RGD:9068941
negative regulation of NK T cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ZBTB7B zinc finger and BTB domain containing 7B JBrowse link 1 133,959,365 133,975,729 RGD:9068941
negative regulation of osteoclast proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GREM1 gremlin 1, DAN family BMP antagonist JBrowse link 15 30,051,483 30,068,243 RGD:9068941
G TNFAIP3 TNF alpha induced protein 3 JBrowse link 6 139,705,255 139,721,264 RGD:9068941
negative regulation of T cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARG1 arginase 1 JBrowse link 6 133,479,966 133,491,162 RGD:9068941
G CD274 CD274 molecule JBrowse link 9 5,454,391 5,474,452 RGD:9068941
G CD80 CD80 molecule JBrowse link 3 123,559,559 123,594,870 RGD:9068941
G CD86 CD86 molecule JBrowse link 3 126,059,008 126,124,339 RGD:9068941
G CLEC4G C-type lectin domain family 4 member G JBrowse link 19 7,870,550 7,873,699 RGD:9068941
G CTLA4 cytotoxic T-lymphocyte associated protein 4 JBrowse link 2B 209,239,417 209,244,498 RGD:9068941
G DLG1 discs large MAGUK scaffold protein 1 JBrowse link 3 204,319,410 204,586,232 RGD:9068941
G DLG5 discs large MAGUK scaffold protein 5 JBrowse link 10 76,974,106 77,110,109 RGD:9068941
G FOXJ1 forkhead box J1 JBrowse link 17 75,637,615 75,642,571 RGD:9068941
G FOXP3 forkhead box P3 JBrowse link X 49,402,652 49,417,029 RGD:9068941
G GLMN glomulin, FKBP associated protein JBrowse link 1 93,646,499 93,701,803 RGD:9068941
G GPNMB glycoprotein nmb JBrowse link 7 23,540,451 23,568,624 RGD:9068941
G HAVCR2 hepatitis A virus cellular receptor 2 JBrowse link 5 159,107,938 159,134,973 RGD:9068941
G IDO1 indoleamine 2,3-dioxygenase 1 JBrowse link 8 36,606,721 36,632,371 RGD:9068941
G IL10 interleukin 10 JBrowse link 1 186,648,289 186,653,155 RGD:9068941
G IL20RB interleukin 20 receptor subunit beta JBrowse link 3 141,457,692 141,504,744 RGD:9068941
G IL2RA interleukin 2 receptor subunit alpha JBrowse link 10 6,037,664 6,086,018 RGD:9068941
G MAD1L1 mitotic arrest deficient 1 like 1 JBrowse link 7 2,187,104 2,604,168 RGD:9068941
G MARCH7 membrane associated ring-CH-type finger 7 JBrowse link 2B 164,377,538 164,432,907 RGD:9068941
G NDFIP1 Nedd4 family interacting protein 1 JBrowse link 5 143,596,345 143,622,913 RGD:9068941
G PAWR pro-apoptotic WT1 regulator JBrowse link 12 79,964,693 80,071,088 RGD:9068941
G PDCD1LG2 programmed cell death 1 ligand 2 JBrowse link 9 5,514,449 5,575,660 RGD:9068941
G PDE5A phosphodiesterase 5A JBrowse link 4 122,832,175 122,966,636 RGD:9068941
G PELI1 pellino E3 ubiquitin protein ligase 1 JBrowse link 2A 65,284,472 65,336,335 RGD:9068941
G PLA2G2D phospholipase A2 group IID JBrowse link 1 20,110,664 20,117,583 RGD:9068941
G PLA2G2F phospholipase A2 group IIF JBrowse link 1 20,138,042 20,149,099 RGD:9068941
G PTPN6 protein tyrosine phosphatase non-receptor type 6 JBrowse link 12 6,991,099 7,008,830 RGD:9068941
G RIPOR2 RHO family interacting cell polarization regulator 2 JBrowse link 6 24,973,412 25,099,034 RGD:9068941
G SCGB1A1 secretoglobin family 1A member 1 JBrowse link 11 61,133,649 61,137,873 RGD:9068941
G SDC4 syndecan 4 JBrowse link 20 42,746,597 42,769,736 RGD:9068941
G SFTPD surfactant protein D JBrowse link 10 78,965,252 78,974,181 RGD:9068941
G SHH sonic hedgehog signaling molecule JBrowse link 7 159,116,966 159,126,660 RGD:9068941
G SPN sialophorin JBrowse link 16 30,034,739 30,037,033 RGD:9068941
G TGFB1 transforming growth factor beta 1 JBrowse link 19 46,831,659 46,852,973 RGD:9068941
G TNFRSF21 TNF receptor superfamily member 21 JBrowse link 6 48,079,749 48,158,356 RGD:9068941
G VSIG4 V-set and immunoglobulin domain containing 4 JBrowse link X 65,211,313 65,228,888 RGD:9068941
G VTCN1 V-set domain containing T cell activation inhibitor 1 JBrowse link 1 120,303,649 120,372,028 RGD:9068941
NK T cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ELF4 E74 like ETS transcription factor 4 JBrowse link X 129,486,097 129,531,764 RGD:9068941
G IL15 interleukin 15 JBrowse link 4 145,307,339 145,416,622 RGD:9068941
osteoclast proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CSF1 colony stimulating factor 1 JBrowse link 1 127,764,916 127,864,188 RGD:9068941
G NPR3 natriuretic peptide receptor 3 JBrowse link 5 82,921,035 83,004,964 RGD:9068941
G TCIRG1 T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 JBrowse link 11 66,429,435 66,441,327 RGD:9068941
G TNFSF11 TNF superfamily member 11 RGD:9068941
positive regulation of activated T cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AGER advanced glycosylation end-product specific receptor JBrowse link 6 32,708,251 32,711,641 RGD:9068941
G CD24 CD24 molecule JBrowse link 6 108,655,555 108,658,505 RGD:9068941
G EPO erythropoietin JBrowse link 7 106,148,062 106,150,974 RGD:9068941
G FADD Fas associated via death domain JBrowse link 11 68,590,184 68,593,905 RGD:9068941
G GPAM glycerol-3-phosphate acyltransferase, mitochondrial JBrowse link 10 112,186,744 112,246,549 RGD:9068941
G HHLA2 HERV-H LTR-associating 2 JBrowse link 3 112,348,805 112,430,321 RGD:9068941
G HMGB1 high mobility group box 1 JBrowse link 13 30,173,875 30,179,527 RGD:9068941
G ICOSLG inducible T cell costimulator ligand JBrowse link 21 43,770,310 43,793,410 RGD:9068941
G IGF1 insulin like growth factor 1 JBrowse link 12 103,385,911 103,463,264 RGD:9068941
G IGF2 insulin like growth factor 2 JBrowse link 11 2,202,764 2,228,890 RGD:9068941
G IGFBP2 insulin like growth factor binding protein 2 JBrowse link 2B 222,498,392 222,527,302 RGD:9068941
G IL12B interleukin 12B JBrowse link 5 161,323,402 161,339,051 RGD:9068941
G IL12RB1 interleukin 12 receptor subunit beta 1 JBrowse link 19 18,513,585 18,541,383 RGD:9068941
G IL18 interleukin 18 JBrowse link 11 110,867,586 110,888,371 RGD:9068941
G IL2 interleukin 2 JBrowse link 4 125,782,563 125,787,819 RGD:9068941
G IL23A interleukin 23 subunit alpha JBrowse link 12 32,828,902 32,830,621 RGD:9068941
G IL23R interleukin 23 receptor JBrowse link 1 68,293,514 68,386,815 RGD:9068941
G IL2RA interleukin 2 receptor subunit alpha JBrowse link 10 6,037,664 6,086,018 RGD:9068941
G IL6R interleukin 6 receptor JBrowse link 1 133,374,078 133,433,089 RGD:9068941
G PYCARD PYD and CARD domain containing JBrowse link 16 31,572,332 31,573,828 RGD:9068941
G RPS3 ribosomal protein S3 JBrowse link 11 73,762,794 73,768,982 RGD:9068941
G STAT5B signal transducer and activator of transcription 5B JBrowse link 17 15,306,412 15,338,973 RGD:9068941
G TMIGD2 transmembrane and immunoglobulin domain containing 2 JBrowse link 19 4,262,536 4,272,212 RGD:9068941
G TNFSF9 TNF superfamily member 9 JBrowse link 19 6,476,941 6,483,352 RGD:9068941
positive regulation of alpha-beta T cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BLM BLM RecQ like helicase JBrowse link 15 88,607,157 88,707,864 RGD:9068941
G CCR2 C-C motif chemokine receptor 2 JBrowse link 3 47,361,118 47,368,312 RGD:9068941
G CD28 CD28 molecule JBrowse link 2B 209,076,388 209,111,213 RGD:9068941
G CD3E CD3e molecule JBrowse link 11 117,074,041 117,085,625 RGD:9068941
G EBI3 Epstein-Barr virus induced 3 JBrowse link 19 4,199,989 4,205,982 RGD:9068941
G LOC100971372 tyrosine-protein kinase ZAP-70 JBrowse link 2A 98,613,740 98,639,742 RGD:9068941
G PTPRC protein tyrosine phosphatase receptor type C JBrowse link 1 178,555,803 178,674,089 RGD:9068941
G RIPK2 receptor interacting serine/threonine kinase 2 JBrowse link 8 88,397,768 88,431,690 RGD:9068941
G SYK spleen associated tyrosine kinase JBrowse link 9 89,959,599 90,056,101 RGD:9068941
G TNFSF4 TNF superfamily member 4 JBrowse link 1 152,391,450 152,699,026 RGD:9068941
positive regulation of B cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADA adenosine deaminase JBrowse link 20 42,044,613 42,076,868 RGD:9068941
G ATAD5 ATPase family AAA domain containing 5 JBrowse link 17 25,435,787 25,496,752 RGD:9068941
G BCL2 BCL2 apoptosis regulator JBrowse link 18 59,797,184 59,993,298 RGD:9068941
G BCL6 BCL6 transcription repressor JBrowse link 3 193,308,296 193,332,452 RGD:9068941
G BST1 bone marrow stromal cell antigen 1 JBrowse link 4 15,451,958 15,480,195 RGD:9068941
G CARD11 caspase recruitment domain family member 11 JBrowse link 7 3,258,736 3,395,626 RGD:9068941
G CD320 CD320 molecule JBrowse link 19 8,438,955 8,445,464 RGD:9068941
G CD38 CD38 molecule JBrowse link 4 15,525,835 15,587,677 RGD:9068941
G CD40 CD40 molecule JBrowse link 20 43,541,619 43,552,994 RGD:9068941
G CD74 CD74 molecule JBrowse link 5 151,830,311 151,841,334 RGD:9068941
G CD81 CD81 molecule JBrowse link 11 2,442,322 2,449,308 RGD:9068941
G CDKN1A cyclin dependent kinase inhibitor 1A JBrowse link 6 37,436,963 37,445,599 RGD:9068941
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit JBrowse link 1 133,535,023 133,547,361 RGD:9068941
G CLCF1 cardiotrophin like cytokine factor 1 JBrowse link 11 66,034,536 66,042,114 RGD:9068941
G FCRL3 Fc receptor like 3 JBrowse link 1 136,830,553 136,855,042 RGD:9068941
G GPR183 G protein-coupled receptor 183 JBrowse link 13 99,600,695 99,613,671 RGD:9068941
G IL13 interleukin 13 JBrowse link 5 134,235,788 134,240,548 RGD:9068941
G IL2 interleukin 2 JBrowse link 4 125,782,563 125,787,819 RGD:9068941
G IL21 interleukin 21 JBrowse link 4 125,940,979 125,951,915 RGD:9068941
G IL4 interleukin 4 JBrowse link 5 134,253,039 134,261,581 RGD:9068941
G IL5 interleukin 5 JBrowse link 5 134,119,608 134,121,682 RGD:9068941
G IL7 interleukin 7 JBrowse link 8 76,894,158 76,967,685 RGD:9068941
G IRS2 insulin receptor substrate 2 JBrowse link 13 110,013,214 110,044,465 RGD:9068941
G MEF2C myocyte enhancer factor 2C JBrowse link 5 26,620,837 26,786,426 RGD:9068941
G MIF macrophage migration inhibitory factor JBrowse link 22 22,729,245 22,732,009 RGD:9068941
G NCKAP1L NCK associated protein 1 like JBrowse link 12 34,932,470 34,977,881 RGD:9068941
G NFATC2 nuclear factor of activated T cells 2 JBrowse link 20 48,858,238 49,034,007 RGD:9068941
G PELI1 pellino E3 ubiquitin protein ligase 1 JBrowse link 2A 65,284,472 65,336,335 RGD:9068941
G PTPRC protein tyrosine phosphatase receptor type C JBrowse link 1 178,555,803 178,674,089 RGD:9068941
G SASH3 SAM and SH3 domain containing 3 JBrowse link X 129,207,049 129,222,342 RGD:9068941
G SLC39A10 solute carrier family 39 member 10 JBrowse link 2B 200,736,327 200,883,524 RGD:9068941
G TCF3 transcription factor 3 JBrowse link 19 1,582,297 1,622,025 RGD:9068941
G TFRC transferrin receptor JBrowse link 3 203,333,953 203,365,586 RGD:9068941
G TICAM1 toll like receptor adaptor molecule 1 JBrowse link 19 4,787,244 4,803,727 RGD:9068941
G TIRAP TIR domain containing adaptor protein JBrowse link 11 125,018,064 125,022,309 RGD:9068941
G TLR4 toll like receptor 4 JBrowse link 9 117,180,250 117,193,510 RGD:9068941
G TNFRSF13C TNF receptor superfamily member 13C JBrowse link 22 40,901,597 40,913,533 RGD:9068941
G TNFRSF4 TNF receptor superfamily member 4 JBrowse link 1 1,168,706 1,171,341 RGD:9068941
G TNFSF13B TNF superfamily member 13b JBrowse link 13 108,536,617 108,575,739 RGD:9068941
G VAV3 vav guanine nucleotide exchange factor 3 JBrowse link 1 109,216,867 109,617,658 RGD:9068941
G WNT3A Wnt family member 3A JBrowse link 1 208,628,706 208,674,469 RGD:9068941
positive regulation of CD4-positive, alpha-beta T cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD55 CD55 molecule (Cromer blood group) JBrowse link 1 187,201,195 187,240,350 RGD:9068941
G CD81 CD81 molecule JBrowse link 11 2,442,322 2,449,308 RGD:9068941
G TGFBR2 transforming growth factor beta receptor 2 JBrowse link 3 30,854,071 30,941,378 RGD:9068941
positive regulation of CD8-positive, alpha-beta T cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PTPN22 protein tyrosine phosphatase non-receptor type 22 JBrowse link 1 123,734,511 123,790,830 RGD:9068941
positive regulation of immature T cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G RIPK2 receptor interacting serine/threonine kinase 2 JBrowse link 8 88,397,768 88,431,690 RGD:9068941
positive regulation of immature T cell proliferation in thymus term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FOXP3 forkhead box P3 JBrowse link X 49,402,652 49,417,029 RGD:9068941
G SHH sonic hedgehog signaling molecule JBrowse link 7 159,116,966 159,126,660 RGD:9068941
positive regulation of leukocyte proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BST2 bone marrow stromal cell antigen 2 JBrowse link 19 17,863,991 17,866,728 RGD:9068941
G IL5RA interleukin 5 receptor subunit alpha JBrowse link 3 3,112,355 3,156,282 RGD:9068941
positive regulation of lymphocyte proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FGF10 fibroblast growth factor 10 JBrowse link 5 71,028,324 71,111,713 RGD:9068941
G IL12A interleukin 12A JBrowse link 3 165,061,505 165,068,666 RGD:9068941
G IL12B interleukin 12B JBrowse link 5 161,323,402 161,339,051 RGD:9068941
G IL6R interleukin 6 receptor JBrowse link 1 133,374,078 133,433,089 RGD:9068941
G MPL MPL proto-oncogene, thrombopoietin receptor JBrowse link 1 44,018,395 44,034,492 RGD:9068941
G MYD88 MYD88 innate immune signal transduction adaptor JBrowse link 3 38,319,024 38,323,572 RGD:9068941
G TAC1 tachykinin precursor 1 JBrowse link 7 103,257,450 103,266,005 RGD:9068941
G TACR1 tachykinin receptor 1 JBrowse link 2A 76,614,478 76,771,018 RGD:9068941
G ZNF335 zinc finger protein 335 JBrowse link 20 43,374,591 43,398,047 RGD:9068941
positive regulation of mast cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G KITLG KIT ligand JBrowse link 12 89,341,921 89,436,081 RGD:9068941
G LYN LYN proto-oncogene, Src family tyrosine kinase JBrowse link 8 49,755,745 49,825,287 RGD:9068941
positive regulation of mononuclear cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CSF1 colony stimulating factor 1 JBrowse link 1 127,764,916 127,864,188 RGD:9068941
G IL12A interleukin 12A JBrowse link 3 165,061,505 165,068,666 RGD:9068941
G IL12B interleukin 12B JBrowse link 5 161,323,402 161,339,051 RGD:9068941
positive regulation of natural killer cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FLT3LG fms related tyrosine kinase 3 ligand JBrowse link 19 55,410,448 55,422,545 RGD:9068941
G IL12B interleukin 12B JBrowse link 5 161,323,402 161,339,051 RGD:9068941
G IL15 interleukin 15 JBrowse link 4 145,307,339 145,416,622 RGD:9068941
G IL18 interleukin 18 JBrowse link 11 110,867,586 110,888,371 RGD:9068941
G IL23A interleukin 23 subunit alpha JBrowse link 12 32,828,902 32,830,621 RGD:9068941
G IL23R interleukin 23 receptor JBrowse link 1 68,293,514 68,386,815 RGD:9068941
G STAT5B signal transducer and activator of transcription 5B JBrowse link 17 15,306,412 15,338,973 RGD:9068941
positive regulation of NK T cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IL12B interleukin 12B JBrowse link 5 161,323,402 161,339,051 RGD:9068941
G IL18 interleukin 18 JBrowse link 11 110,867,586 110,888,371 RGD:9068941
G IL23A interleukin 23 subunit alpha JBrowse link 12 32,828,902 32,830,621 RGD:9068941
G RASAL3 RAS protein activator like 3 JBrowse link 19 15,969,412 15,981,800 RGD:9068941
positive regulation of osteoclast proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FLT3LG fms related tyrosine kinase 3 ligand JBrowse link 19 55,410,448 55,422,545 RGD:9068941
G OCSTAMP osteoclast stimulatory transmembrane protein JBrowse link 20 43,958,499 43,968,118 RGD:9068941
G PTH parathyroid hormone JBrowse link 11 13,347,829 13,351,951 RGD:9068941
positive regulation of T cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AIF1 allograft inflammatory factor 1 JBrowse link 6 32,166,301 32,168,125 RGD:9068941
G ANXA1 annexin A1 JBrowse link 9 71,930,148 71,948,779 RGD:9068941
G BTNL2 butyrophilin like 2 JBrowse link 6 32,944,694 32,950,097 RGD:9068941
G CARD11 caspase recruitment domain family member 11 JBrowse link 7 3,258,736 3,395,626 RGD:9068941
G CCDC88B coiled-coil domain containing 88B JBrowse link 11 63,042,107 63,058,480 RGD:9068941
G CCL19 C-C motif chemokine ligand 19 JBrowse link 9 35,334,353 35,336,108 RGD:9068941
G CCL5 C-C motif chemokine ligand 5 JBrowse link 17 21,210,798 21,219,172 RGD:9068941
G CD1D CD1d molecule JBrowse link 1 137,339,774 137,348,173 RGD:9068941
G CD274 CD274 molecule JBrowse link 9 5,454,391 5,474,452 RGD:9068941
G CD276 CD276 molecule JBrowse link 15 71,351,368 71,380,383 RGD:9068941
G CD28 CD28 molecule JBrowse link 2B 209,076,388 209,111,213 RGD:9068941
G CD3E CD3e molecule JBrowse link 11 117,074,041 117,085,625 RGD:9068941
G CD4 CD4 molecule JBrowse link 12 6,834,011 6,864,204 RGD:9068941
G CD40LG CD40 ligand JBrowse link X 136,042,849 136,055,158 RGD:9068941
G CD46 CD46 molecule JBrowse link 1 188,138,616 188,182,046 RGD:9068941
G CD6 CD6 molecule JBrowse link 11 59,691,762 59,723,974 RGD:9068941
G CD70 CD70 molecule JBrowse link 19 6,535,559 6,542,310 RGD:9068941
G CD80 CD80 molecule JBrowse link 3 123,559,559 123,594,870 RGD:9068941
G CD86 CD86 molecule JBrowse link 3 126,059,008 126,124,339 RGD:9068941
G CLECL1 C-type lectin like 1 JBrowse link 12 10,013,032 10,030,553 RGD:9068941
G CORO1A coronin 1A JBrowse link 16 30,549,880 30,555,093 RGD:9068941
G DNAJA3 DnaJ heat shock protein family (Hsp40) member A3 JBrowse link 16 4,519,965 4,550,786 RGD:9068941
G EFNB1 ephrin B1 JBrowse link X 68,139,078 68,152,127 RGD:9068941
G HAVCR2 hepatitis A virus cellular receptor 2 JBrowse link 5 159,107,938 159,134,973 RGD:9068941
G HES1 hes family bHLH transcription factor 1 JBrowse link 3 201,749,044 201,751,591 RGD:9068941
G IL12A interleukin 12A JBrowse link 3 165,061,505 165,068,666 RGD:9068941
G IL12B interleukin 12B JBrowse link 5 161,323,402 161,339,051 RGD:9068941
G IL15 interleukin 15 JBrowse link 4 145,307,339 145,416,622 RGD:9068941
G IL1B interleukin 1 beta JBrowse link 2A 113,846,299 113,853,424 RGD:9068941
G IL21 interleukin 21 JBrowse link 4 125,940,979 125,951,915 RGD:9068941
G IL23A interleukin 23 subunit alpha JBrowse link 12 32,828,902 32,830,621 RGD:9068941
G IL23R interleukin 23 receptor JBrowse link 1 68,293,514 68,386,815 RGD:9068941
G IL4 interleukin 4 JBrowse link 5 134,253,039 134,261,581 RGD:9068941
G IL6 interleukin 6 JBrowse link 7 23,027,560 23,032,419 RGD:9068941
G IL6ST interleukin 6 signal transducer JBrowse link 5 59,650,833 59,708,817 RGD:9068941
G JAK3 Janus kinase 3 JBrowse link 19 18,283,157 18,304,641 RGD:9068941
G LEP leptin JBrowse link 7 132,884,994 132,901,519 RGD:9068941
G LOC100995226 HLA class II histocompatibility antigen, DP beta 1 chain JBrowse link 6 33,763,566 33,774,387 RGD:9068941
G LOC100995577 HLA class II histocompatibility antigen, DP alpha 1 chain JBrowse link 6 33,752,638 33,768,418 RGD:9068941
G MHC-DMB HLA class II histocompatibility antigen, DM beta chain JBrowse link 6 33,619,511 33,625,956 RGD:9068941
G NCK1 NCK adaptor protein 1 JBrowse link 3 141,362,407 141,451,444 RGD:9068941
G NCK2 NCK adaptor protein 2 JBrowse link 2A 106,827,621 106,976,362 RGD:9068941
G NCKAP1L NCK associated protein 1 like JBrowse link 12 34,932,470 34,977,881 RGD:9068941
G PDCD1LG2 programmed cell death 1 ligand 2 JBrowse link 9 5,514,449 5,575,660 RGD:9068941
G PNP purine nucleoside phosphorylase JBrowse link 14 19,396,114 19,403,907 RGD:9068941
G PRKCQ protein kinase C theta JBrowse link 10 6,440,316 6,528,828 RGD:9068941
G PTPRC protein tyrosine phosphatase receptor type C JBrowse link 1 178,555,803 178,674,089 RGD:9068941
G SASH3 SAM and SH3 domain containing 3 JBrowse link X 129,207,049 129,222,342 RGD:9068941
G SELENOK selenoprotein K JBrowse link 3 55,044,026 55,050,960 RGD:9068941
G SPTA1 spectrin alpha, erythrocytic 1 JBrowse link 1 137,760,188 137,836,131 RGD:9068941
G TFRC transferrin receptor JBrowse link 3 203,333,953 203,365,586 RGD:9068941
G TNFRSF13C TNF receptor superfamily member 13C JBrowse link 22 40,901,597 40,913,533 RGD:9068941
G TNFSF13B TNF superfamily member 13b JBrowse link 13 108,536,617 108,575,739 RGD:9068941
G TRAF6 TNF receptor associated factor 6 JBrowse link 11 36,330,336 36,356,334 RGD:9068941
G VCAM1 vascular cell adhesion molecule 1 JBrowse link 1 102,091,121 102,108,494 RGD:9068941
G VTCN1 V-set domain containing T cell activation inhibitor 1 JBrowse link 1 120,303,649 120,372,028 RGD:9068941
G ZP4 zona pellucida glycoprotein 4 JBrowse link 1 218,433,473 218,442,383 RGD:9068941
regulation of activated T cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD274 CD274 molecule JBrowse link 9 5,454,391 5,474,452 RGD:9068941
G IDO1 indoleamine 2,3-dioxygenase 1 JBrowse link 8 36,606,721 36,632,371 RGD:9068941
G RIPK3 receptor interacting serine/threonine kinase 3 JBrowse link 14 23,235,796 23,239,821 RGD:9068941
regulation of B cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AHR aryl hydrocarbon receptor JBrowse link 7 17,278,637 17,326,171 RGD:9068941
G CD22 CD22 molecule JBrowse link 19 41,012,271 41,030,719 RGD:9068941
G IKZF3 IKAROS family zinc finger 3 JBrowse link 17 17,643,750 17,741,492 RGD:9068941
G MZB1 marginal zone B and B1 cell specific protein JBrowse link 5 140,881,415 140,883,756 RGD:9068941
regulation of CD8-positive, alpha-beta T cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IRF1 interferon regulatory factor 1 JBrowse link 5 134,066,250 134,075,035 RGD:9068941
G MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 JBrowse link 11 46,332,121 46,352,750 RGD:9068941
G SH3RF1 SH3 domain containing ring finger 1 JBrowse link 4 173,392,485 173,569,072 RGD:9068941
regulation of leukocyte proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HHEX hematopoietically expressed homeobox JBrowse link 10 92,947,373 92,952,992 RGD:9068941
regulation of natural killer cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LEP leptin JBrowse link 7 132,884,994 132,901,519 RGD:9068941
G PTPN22 protein tyrosine phosphatase non-receptor type 22 JBrowse link 1 123,734,511 123,790,830 RGD:9068941
regulation of T cell homeostatic proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IL2 interleukin 2 JBrowse link 4 125,782,563 125,787,819 RGD:9068941
G IL2RA interleukin 2 receptor subunit alpha JBrowse link 10 6,037,664 6,086,018 RGD:9068941
G LMO1 LIM domain only 1 JBrowse link 11 8,088,223 8,127,704 RGD:9068941
regulation of T cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CTLA4 cytotoxic T-lymphocyte associated protein 4 JBrowse link 2B 209,239,417 209,244,498 RGD:9068941
G CTNNB1 catenin beta 1 JBrowse link 3 41,372,368 41,414,030 RGD:9068941
G IL27 interleukin 27 JBrowse link 16 28,979,717 28,984,655 RGD:9068941
G LGALS3 galectin 3 JBrowse link 14 53,990,023 54,006,412 RGD:9068941
G RAC2 Rac family small GTPase 2 JBrowse link 22 35,973,229 35,992,026 RGD:9068941
G SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 JBrowse link 2A 39,773,758 39,911,964 RGD:9068941
G TNFRSF1B TNF receptor superfamily member 1B JBrowse link 1 12,130,663 12,172,646 RGD:9068941
G TNFSF18 TNF superfamily member 18 JBrowse link 1 152,251,683 152,262,668 RGD:9068941
G TNFSF8 TNF superfamily member 8 JBrowse link 9 114,360,206 114,397,465 RGD:9068941
G TNFSF9 TNF superfamily member 9 JBrowse link 19 6,476,941 6,483,352 RGD:9068941
T cell homeostatic proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BAX BCL2 associated X, apoptosis regulator JBrowse link 19 54,793,594 54,800,466 RGD:9068941
T cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CCND3 cyclin D3 JBrowse link 6 42,820,569 42,932,944 RGD:9068941
G CD151 CD151 molecule (Raph blood group) JBrowse link 11 895,802 900,289 RGD:9068941
G CTPS1 CTP synthase 1 JBrowse link 1 41,592,069 41,624,455 RGD:9068941
G EBI3 Epstein-Barr virus induced 3 JBrowse link 19 4,199,989 4,205,982 RGD:9068941
G FKBP1B FKBP prolyl isomerase 1B JBrowse link 2A 24,145,893 24,162,842 RGD:9068941
G GJA1 gap junction protein alpha 1 JBrowse link 6 123,348,744 123,360,887 RGD:9068941
G IL23A interleukin 23 subunit alpha JBrowse link 12 32,828,902 32,830,621 RGD:9068941
G MALT1 MALT1 paracaspase JBrowse link 18 55,395,462 55,473,574 RGD:9068941
G MSN moesin JBrowse link X 64,859,691 64,933,014 RGD:9068941
G NCSTN nicastrin JBrowse link 1 139,618,229 139,633,911 RGD:9068941
G P2RX7 purinergic receptor P2X 7 JBrowse link 12 122,102,888 122,154,068 RGD:9068941
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma JBrowse link 7 111,569,947 111,611,614 RGD:9068941
G PPP3CB protein phosphatase 3 catalytic subunit beta JBrowse link 10 72,443,051 72,501,752 RGD:9068941
G PRDX2 peroxiredoxin 2 JBrowse link 19 13,103,422 13,107,369 RGD:9068941
G PSMB10 proteasome subunit beta 10 JBrowse link 16 67,663,344 67,666,359 RGD:9068941
G PTPRC protein tyrosine phosphatase receptor type C JBrowse link 1 178,555,803 178,674,089 RGD:9068941
G RC3H1 ring finger and CCCH-type domains 1 JBrowse link 1 153,153,048 153,213,402 RGD:9068941
G RC3H2 ring finger and CCCH-type domains 2 JBrowse link 9 122,308,725 122,365,106 RGD:9068941
G RIPK2 receptor interacting serine/threonine kinase 2 JBrowse link 8 88,397,768 88,431,690 RGD:9068941
G TNFRSF4 TNF receptor superfamily member 4 JBrowse link 1 1,168,706 1,171,341 RGD:9068941
G TNFSF14 TNF superfamily member 14 JBrowse link 19 6,614,372 6,621,763 RGD:9068941
T cell proliferation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC100972194 40S ribosomal protein S6 JBrowse link 9 19,674,380 19,678,397 RGD:9068941
G SLC11A1 solute carrier family 11 member 1 JBrowse link 2B 224,238,284 224,252,941 RGD:9068941
G TNFSF18 TNF superfamily member 18 JBrowse link 1 152,251,683 152,262,668 RGD:9068941
G TP53 tumor protein p53 JBrowse link 17 7,687,132 7,706,120 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15692
    cell population proliferation 1956
      leukocyte proliferation 284
        macrophage proliferation + 6
        mast cell proliferation + 4
        monocyte proliferation 0
        mononuclear cell proliferation + 263
        negative regulation of leukocyte proliferation + 74
        osteoclast proliferation + 9
        positive regulation of leukocyte proliferation + 136
        regulation of leukocyte proliferation + 216
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.