ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of leukocyte proliferation
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Accession:GO:0070664 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte proliferation.
Synonyms:exact_synonym: down regulation of leukocyte proliferation;   downregulation of leukocyte proliferation
 narrow_synonym: inhibition of leukocyte proliferation


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negative regulation of leukocyte proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl12 chemokine (C-C motif) ligand 12 JBrowse link 10 69,476,866 69,478,416 RGD:9685052
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:1624291
RGD:1600115
negative regulation of activated T cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arg1 arginase 1 JBrowse link 1 21,525,421 21,537,872 RGD:1624291
RGD:1600115
G Btn1a1 butyrophilin, subfamily 1, member A1 JBrowse link 17 43,899,155 43,909,042 RGD:1624291
G Btn2a2 butyrophilin, subfamily 2, member A2 JBrowse link 17 43,867,243 43,878,734 RGD:1624291
RGD:1600115
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:1624291
RGD:1600115
G Cd274 CD274 molecule JBrowse link 1 247,519,890 247,539,659 RGD:1624291
RGD:1600115
G Ido1 indoleamine 2,3-dioxygenase 1 JBrowse link 16 72,216,326 72,228,098 RGD:1624291
RGD:1600115
G Lgals9 galectin 9 JBrowse link 10 64,737,022 64,760,195 RGD:1624291
G Lrrc32 leucine rich repeat containing 32 JBrowse link 1 163,443,972 163,457,426 RGD:1624291
RGD:1600115
G Pdcd1lg2 programmed cell death 1 ligand 2 JBrowse link 1 247,562,202 247,629,279 RGD:1624291
RGD:1600115
G Prkar1a protein kinase cAMP-dependent type I regulatory subunit alpha JBrowse link 10 97,940,705 97,959,199 RGD:1624291
RGD:1600115
G Prnp prion protein JBrowse link 3 124,515,917 124,531,320 RGD:1624291
RGD:1600115
G Rc3h1 ring finger and CCCH-type domains 1 JBrowse link 13 78,723,028 78,794,663 RGD:1624291
negative regulation of alpha-beta T cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Btla B and T lymphocyte associated JBrowse link 11 60,523,692 60,547,234 RGD:1624291
G Cblb Cbl proto-oncogene B JBrowse link 11 51,037,383 51,202,761 RGD:1624291
G Itch itchy E3 ubiquitin protein ligase JBrowse link 3 150,660,665 150,752,016 RGD:1624291
RGD:1600115
G Tnfrsf14 TNF receptor superfamily member 14 JBrowse link 5 172,328,259 172,337,221 RGD:1624291
RGD:13792537
negative regulation of B cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:1624291
RGD:1600115
G Btk Bruton tyrosine kinase JBrowse link X 105,360,922 105,390,580 RGD:1624291
RGD:1600115
G Btla B and T lymphocyte associated JBrowse link 11 60,523,692 60,547,234 RGD:1624291
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:1624291
RGD:1600115
G Cd24 CD24 molecule JBrowse link 20 48,335,540 48,340,847 RGD:1624291
RGD:1600115
G Cd300a Cd300a molecule JBrowse link 10 103,437,978 103,451,170 RGD:1624291
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:1624291
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 JBrowse link 9 67,699,397 67,706,068 RGD:1624291
RGD:1600115
G Fcgr2b Fc fragment of IgG receptor IIb JBrowse link 13 89,329,298 89,343,916 RGD:1624291
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:1624291
RGD:1600115
G Inpp5d inositol polyphosphate-5-phosphatase D JBrowse link 9 94,745,220 94,850,778 RGD:1624291
RGD:1600115
G Lyn LYN proto-oncogene, Src family tyrosine kinase JBrowse link 5 16,526,058 16,642,648 RGD:1624291
RGD:13792537
G Mnda myeloid cell nuclear differentiation antigen JBrowse link 13 92,073,664 92,091,335 RGD:1624291
G Pawr pro-apoptotic WT1 regulator JBrowse link 7 51,273,764 51,353,700 RGD:1624291
RGD:1600115
G Pkn1 protein kinase N1 JBrowse link 19 24,803,524 24,832,305 RGD:1624291
RGD:1600115
G Prdm1 PR/SET domain 1 JBrowse link 20 49,464,921 49,556,623 RGD:1624291
G Rc3h1 ring finger and CCCH-type domains 1 JBrowse link 13 78,723,028 78,794,663 RGD:1624291
G Tnfrsf13b TNF receptor superfamily member 13B JBrowse link 10 47,399,834 47,422,907 RGD:1624291
RGD:13792537
G Tnfrsf21 TNF receptor superfamily member 21 JBrowse link 9 20,546,159 20,621,051 RGD:1624291
RGD:13792537
RGD:1600115
G Tyrobp Tyro protein tyrosine kinase binding protein JBrowse link 1 88,875,370 88,879,305 RGD:1600115
RGD:1624291
negative regulation of CD4-positive, alpha-beta T cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arg2 arginase 2 JBrowse link 6 102,311,097 102,338,406 RGD:1600115
RGD:1624291
G Cd274 CD274 molecule JBrowse link 1 247,519,890 247,539,659 RGD:1600115
RGD:1624291
G Cd44 CD44 molecule (Indian blood group) JBrowse link 3 92,695,083 92,783,820 RGD:1624291
G Lgals9 galectin 9 JBrowse link 10 64,737,022 64,760,195 RGD:1624291
G Tarm1 T cell-interacting, activating receptor on myeloid cells 1 JBrowse link 1 64,241,742 64,256,646 RGD:1624291
RGD:1600115
G Twsg1 twisted gastrulation BMP signaling modulator 1 JBrowse link 9 113,699,151 113,732,601 RGD:1624291
G Vsir V-set immunoregulatory receptor JBrowse link 20 29,897,543 29,923,381 RGD:1624291
G Xcl1 X-C motif chemokine ligand 1 JBrowse link 13 83,199,402 83,202,845 RGD:1624291
negative regulation of CD8-positive, alpha-beta T cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Vsir V-set immunoregulatory receptor JBrowse link 20 29,897,543 29,923,381 RGD:1624291
negative regulation of immature T cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gnrh1 gonadotropin releasing hormone 1 JBrowse link 15 44,441,856 44,446,064 RGD:9685051
negative regulation of immature T cell proliferation in thymus term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1624291
RGD:1600115
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:1624291
G Erbb2 erb-b2 receptor tyrosine kinase 2 JBrowse link 10 86,367,596 86,391,728 RGD:1624291
G Ihh Indian hedgehog signaling molecule JBrowse link 9 82,208,223 82,214,440 RGD:1624291
RGD:1600115
G Tmem131l transmembrane 131 like JBrowse link 2 182,897,332 183,031,273 RGD:1624291
RGD:1600115
negative regulation of lymphocyte proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
G Gal galanin and GMAP prepropeptide JBrowse link 1 218,653,059 218,657,922 RGD:728693
G Il2 interleukin 2 JBrowse link 2 123,847,150 123,851,854 RGD:1624291
G Il2ra interleukin 2 receptor subunit alpha JBrowse link 17 70,500,672 70,547,929 RGD:1624291
G Kng2 kininogen 2 JBrowse link 11 81,509,185 81,516,759 RGD:1600541
G Lst1 leukocyte specific transcript 1 JBrowse link 20 5,175,213 5,179,352 RGD:1624291
G Sox11 SRY box 11 JBrowse link 6 46,629,967 46,631,988 RGD:1624291
RGD:1600115
negative regulation of mast cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Enpp3 ectonucleotide pyrophosphatase/phosphodiesterase 3 JBrowse link 1 21,613,148 21,684,483 RGD:1600115
RGD:1624291
G Lyn LYN proto-oncogene, Src family tyrosine kinase JBrowse link 5 16,526,058 16,642,648 RGD:1624291
RGD:13792537
RGD:1600115
negative regulation of NK T cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Zbtb7b zinc finger and BTB domain containing 7B JBrowse link 2 188,704,989 188,719,674 RGD:1600115
RGD:1624291
negative regulation of osteoclast proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Grem1 gremlin 1, DAN family BMP antagonist JBrowse link 3 105,203,309 105,214,989 RGD:1624291
RGD:1600115
negative regulation of T cell homeostatic proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd24 CD24 molecule JBrowse link 20 48,335,540 48,340,847 RGD:1624291
RGD:1600115
negative regulation of T cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arg1 arginase 1 JBrowse link 1 21,525,421 21,537,872 RGD:1624291
G Btla B and T lymphocyte associated JBrowse link 11 60,523,692 60,547,234 RGD:1624291
G Cd274 CD274 molecule JBrowse link 1 247,519,890 247,539,659 RGD:1624291
RGD:13792537
G Cd276 Cd276 molecule JBrowse link 8 63,312,060 63,350,411 RGD:1624291
RGD:1600115
G Cd80 Cd80 molecule JBrowse link 11 64,815,201 64,855,293 RGD:13792537
G Cd86 CD86 molecule JBrowse link 11 67,060,305 67,117,990 RGD:13792537
G Ceacam1 carcinoembryonic antigen related cell adhesion molecule 1 JBrowse link 1 82,327,955 82,344,345 RGD:1624291
G Cebpb CCAAT/enhancer binding protein beta JBrowse link 3 164,424,502 164,425,933 RGD:1624291
RGD:1600115
G Clec4g C-type lectin domain family 4, member G JBrowse link 12 2,273,649 2,278,594 RGD:1624291
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 JBrowse link 9 67,699,397 67,706,068 RGD:2302005
G Dlg1 discs large MAGUK scaffold protein 1 JBrowse link 11 72,164,566 72,378,895 RGD:1624291
RGD:1600115
G Dlg5 discs large MAGUK scaffold protein 5 JBrowse link 15 120,213 230,312 RGD:1624291
RGD:1600115
G Foxj1 forkhead box J1 JBrowse link 10 105,282,090 105,289,396 RGD:1624291
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
RGD:1600115
G Glmn glomulin, FKBP associated protein JBrowse link 14 3,204,390 3,247,703 RGD:1624291
RGD:1600115
G Gpnmb glycoprotein nmb JBrowse link 4 78,694,447 78,715,685 RGD:1624291
RGD:1600115
G Havcr2 hepatitis A virus cellular receptor 2 JBrowse link 10 31,561,838 31,590,624 RGD:1624291
G Ido1 indoleamine 2,3-dioxygenase 1 JBrowse link 16 72,216,326 72,228,098 RGD:1624291
G Il20rb interleukin 20 receptor subunit beta JBrowse link 8 108,745,906 108,778,561 RGD:1624291
RGD:1600115
G Il2ra interleukin 2 receptor subunit alpha JBrowse link 17 70,500,672 70,547,929 RGD:1624291
RGD:1600115
G Kng2 kininogen 2 JBrowse link 11 81,509,185 81,516,759 RGD:1600541
G Lilrb2 leukocyte immunoglobulin like receptor B2 JBrowse link 1 63,734,135 63,741,986 RGD:1624291
G Mad1l1 mitotic arrest deficient 1 like 1 JBrowse link 12 16,410,083 16,721,232 RGD:1624291
RGD:1600115
G March7 membrane associated ring-CH-type finger 7 JBrowse link 3 46,284,961 46,325,230 RGD:1624291
RGD:1600115
G Ndfip1 Nedd4 family interacting protein 1 JBrowse link 18 31,574,759 31,625,286 RGD:1624291
G Pawr pro-apoptotic WT1 regulator JBrowse link 7 51,273,764 51,353,700 RGD:1624291
RGD:1600115
G Pdcd1lg2 programmed cell death 1 ligand 2 JBrowse link 1 247,562,202 247,629,279 RGD:1624291
RGD:13792537
G Pde5a phosphodiesterase 5A JBrowse link 2 226,899,604 227,044,916 RGD:1624291
RGD:1600115
G Peli1 pellino E3 ubiquitin protein ligase 1 JBrowse link 14 106,008,086 106,062,566 RGD:1624291
RGD:1600115
G Pla2g2d phospholipase A2, group IID JBrowse link 5 157,222,636 157,228,795 RGD:1624291
RGD:13792537
G Pla2g2f phospholipase A2, group IIF JBrowse link 5 157,192,047 157,217,265 RGD:1624291
RGD:13792537
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 JBrowse link 4 157,239,141 157,263,890 RGD:1624291
RGD:1600115
G Ripor2 RHO family interacting cell polarization regulator 2 JBrowse link 17 42,324,594 42,549,907 RGD:1624291
G RT1-Ba RT1 class II, locus Ba JBrowse link 20 4,066,133 4,070,726 RGD:5147666
G RT1-Bb RT1 class II, locus Bb JBrowse link 20 4,043,726 4,049,367 RGD:5147666
G RT1-Db1 RT1 class II, locus Db1 JBrowse link 20 4,087,621 4,097,190 RGD:1624291
G Scgb1a1 secretoglobin family 1A member 1 JBrowse link 1 225,279,698 225,283,246 RGD:1624291
RGD:1600115
G Sdc4 syndecan 4 JBrowse link 3 160,872,503 160,891,190 RGD:1624291
RGD:1600115
G Sftpd surfactant protein D JBrowse link 16 18,753,535 18,766,100 RGD:4144057
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1624291
RGD:1600115
G Spn sialophorin JBrowse link 1 198,572,999 198,585,664 RGD:1600115
RGD:1624291
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
RGD:1600115
G Tnfrsf21 TNF receptor superfamily member 21 JBrowse link 9 20,546,159 20,621,051 RGD:1624291
RGD:13792537
RGD:1600115
G Vsig4 V-set and immunoglobulin domain containing 4 JBrowse link X 65,370,851 65,400,298 RGD:1624291
RGD:1600115
G Vtcn1 V-set domain containing T cell activation inhibitor 1 JBrowse link 2 203,200,435 203,274,264 RGD:1624291
RGD:1600115
G Zc3h12d zinc finger CCCH type containing 12D JBrowse link 1 1,937,620 1,972,919 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17896
    cell population proliferation 2082
      leukocyte proliferation 323
        negative regulation of leukocyte proliferation 91
          negative regulation of macrophage proliferation 0
          negative regulation of mast cell proliferation 2
          negative regulation of mononuclear cell proliferation + 87
          negative regulation of osteoclast proliferation 1
Path 2
Term Annotations click to browse term
  biological_process 17896
    biological regulation 12607
      regulation of biological process 11951
        negative regulation of biological process 5354
          negative regulation of cellular process 4779
            negative regulation of cell population proliferation 705
              negative regulation of leukocyte proliferation 91
                negative regulation of macrophage proliferation 0
                negative regulation of mast cell proliferation 2
                negative regulation of mononuclear cell proliferation + 87
                negative regulation of osteoclast proliferation 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.