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ONTOLOGY REPORT - ANNOTATIONS


Term:response to interleukin-2
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Accession:GO:0070669 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-2 stimulus.
Synonyms:exact_synonym: response to IL-2


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response to interleukin-2 term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 ISO
ISS
(MGI:MGI:1312962|PMID:9811838)
GO_REF:0000024
RGD
UniProt
PMID:9811838 GO_REF:0000024, MGI:MGI:1312962 NCBI chr  X:72,128,996...72,133,692
Ensembl chr  X:72,128,994...72,133,692
JBrowse link
G Stat5b signal transducer and activator of transcription 5B ISO
IEA
MGI:MGI:2181592 (MGI:MGI:3655409|PMID:9841920)
GO_REF:0000107
RGD
Ensembl
PMID:9841920 GO_REF:0000107, MGI:MGI:3655409 NCBI chr10:88,686,207...88,712,313
Ensembl chr10:88,686,207...88,754,829
JBrowse link
cellular response to interleukin-2 term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc5l cell division cycle 5-like IEP RGD PMID:11694351 RGD:10047049 NCBI chr 9:17,949,764...17,988,514
Ensembl chr 9:17,949,764...17,988,509
JBrowse link
G Cpd carboxypeptidase D IEP RGD PMID:11181555 RGD:1298782 NCBI chr10:63,325,764...63,389,811
Ensembl chr10:63,325,199...63,389,817
JBrowse link
interleukin-2-mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il2ra interleukin 2 receptor subunit alpha IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr17:70,500,672...70,547,929
Ensembl chr17:70,499,083...70,548,071
JBrowse link
G Il2rb interleukin 2 receptor subunit beta ISO
IEA
ISS
(PMID:31040184)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:31040184 GO_REF:0000024, GO_REF:0000107 NCBI chr 7:119,701,338...119,716,238
Ensembl chr 7:119,701,251...119,716,238
JBrowse link
G Jak1 Janus kinase 1 ISO (PMID:11909529) RGD PMID:11909529 NCBI chr 5:119,982,503...120,091,452
Ensembl chr 5:119,982,943...120,083,904
JBrowse link
negative regulation of interleukin-2-mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 ISO
ISS
(PMID:11909529)
(MGI:MGI:3691503|PMID:11909529)
GO_REF:0000024
RGD
UniProt
PMID:11909529 GO_REF:0000024, MGI:MGI:3691503 NCBI chr18:63,415,298...63,489,240
Ensembl chr18:63,415,306...63,488,027
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    response to stimulus 10583
      response to chemical 6342
        response to organic substance 3865
          response to cytokine 1132
            response to interleukin-2 8
              cellular response to interleukin-2 + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.