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ONTOLOGY REPORT - ANNOTATIONS


Term:response to interleukin-18
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Accession:GO:0070673 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-18 stimulus.
Synonyms:exact_synonym: response to IL-18


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response to interleukin-18 term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cldn1 claudin 1 IMP RGD PMID:22001439 RGD:8655996 NCBI chr11:77,815,216...77,830,373
Ensembl chr11:77,815,181...77,830,416
JBrowse link
G Ocln occludin IMP RGD PMID:22001439 RGD:8655996 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 ISO MGI:MGI:2446070|MGI:MGI:2660793 (MGI:MGI:2176422|PMID:11894098), (MGI:MGI:2176424|PMID:11894097) RGD PMID:11894097, PMID:11894098 MGI:MGI:2176422, MGI:MGI:2176424 NCBI chr 5:29,838,713...29,870,390
Ensembl chr 5:29,838,747...29,870,735
JBrowse link
cellular response to interleukin-18 term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma ISO (MGI:MGI:4355633|PMID:19666510) RGD PMID:19666510 MGI:MGI:4355633 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il18rap interleukin 18 receptor accessory protein ISO MGI:MGI:3579137 (MGI:MGI:3578455|PMID:15843532) RGD PMID:15843532 MGI:MGI:3578455 NCBI chr 9:47,225,543...47,255,805
Ensembl chr 9:47,225,585...47,258,503
JBrowse link
interleukin-18-mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 ISO (PMID:21321938) RGD PMID:21321938 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Il18 interleukin 18 IEA
ISO
ISS
GO_REF:0000107
(PMID:21321938), (PMID:25500532)
GO_REF:0000024
(MGI:MGI:3578455|PMID:15843532)
Ensembl
RGD
UniProt
PMID:15843532, PMID:21321938, PMID:25500532 GO_REF:0000024, GO_REF:0000107, MGI:MGI:3578455 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il18r1 interleukin 18 receptor 1 ISO
IBA
MGI:MGI:2136765 (MGI:MGI:2136797|PMID:10227969)
PMID:21873635
(PMID:25500532)
RGD PMID:10227969, PMID:25500532, PMID:21873635 MGI:MGI:2136797, RGD:13792537 NCBI chr 9:47,184,404...47,217,403
Ensembl chr 9:47,185,443...47,219,175
JBrowse link
G Il18rap interleukin 18 receptor accessory protein ISO
IBA
MGI:MGI:3579137 (MGI:MGI:3578455|PMID:15843532)
PMID:21873635
(PMID:25500532)
RGD PMID:15843532, PMID:25500532, PMID:21873635 MGI:MGI:3578455, RGD:13792537 NCBI chr 9:47,225,543...47,255,805
Ensembl chr 9:47,225,585...47,258,503
JBrowse link
G Pdgfb platelet derived growth factor subunit B IEA
ISO
GO_REF:0000107
(PMID:21321938)
Ensembl
RGD
PMID:21321938 GO_REF:0000107 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
positive regulation of interleukin-18-mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ticam2 toll-like receptor adaptor molecule 2 ISO (PMID:22685567)
(MGI:MGI:5488868|PMID:22685567)
RGD PMID:22685567 MGI:MGI:5488868 NCBI chr18:40,555,106...40,572,569
Ensembl chr18:40,555,106...40,572,241
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    response to stimulus 10583
      response to chemical 6343
        response to organic substance 3865
          response to cytokine 1132
            response to interleukin-18 10
              cellular response to interleukin-18 + 7
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.