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ONTOLOGY REPORT - ANNOTATIONS


Term:response to cholesterol
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Accession:GO:0070723 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus.


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response to cholesterol term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 IEA
ISO
GO_REF:0000107
(PMID:11178988)
Ensembl
RGD
PMID:11178988 GO_REF:0000107 NCBI chr 3:2,648,787...2,668,770
Ensembl chr 3:2,648,885...2,668,809
JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant IEP RGD PMID:19110235 RGD:2315908 NCBI chr 8:23,142,733...23,149,067
Ensembl chr 8:23,142,734...23,148,396
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 IEP RGD PMID:9722683 RGD:69375 NCBI chr 1:276,240,703...276,290,012
Ensembl chr 1:276,240,703...276,290,008
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 ISO
ISS
(PMID:19523456)
GO_REF:0000024
RGD
UniProt
PMID:19523456 GO_REF:0000024 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 IEP RGD PMID:20435353 RGD:4889907 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 IEA
ISO
GO_REF:0000107
(PMID:19523456)
Ensembl
RGD
PMID:19523456 GO_REF:0000107 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 IEP RGD PMID:25263431 RGD:15045610 NCBI chr 8:130,548,418...130,550,388
Ensembl chr 8:130,548,418...130,550,388
JBrowse link
G F7 coagulation factor VII IDA RGD PMID:15670042 RGD:11049546 NCBI chr16:81,824,610...81,834,923
Ensembl chr16:81,824,111...81,834,945
JBrowse link
G Fdps farnesyl diphosphate synthase IEP RGD PMID:2909544 RGD:2316308 NCBI chr 2:188,403,595...188,413,219
Ensembl chr 2:188,392,858...188,413,219
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase IEP RGD PMID:25263431 RGD:15045610 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 IEP RGD PMID:2903839 RGD:2326164 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 IEP RGD PMID:25263431 RGD:15045610 NCBI chr 3:80,004,130...80,014,197
Ensembl chr 3:80,004,130...80,012,750
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 IEP RGD PMID:25263431 RGD:15045610 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Pmvk phosphomevalonate kinase ISO (PMID:10191291) RGD PMID:10191291 NCBI chr 2:188,784,329...188,793,890
Ensembl chr 2:188,784,222...188,793,895
JBrowse link
G Smad2 SMAD family member 2 ISO (PMID:17878231) RGD PMID:17878231 NCBI chr18:72,550,107...72,612,078
Ensembl chr18:72,550,219...72,612,078
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO
ISS
(PMID:17878231)
GO_REF:0000024
RGD
UniProt
PMID:17878231 GO_REF:0000024 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 ISO (PMID:17878231)
(MGI:MGI:3766844|PMID:17878231)
RGD PMID:17878231 MGI:MGI:3766844 NCBI chr 5:63,056,071...63,119,635
Ensembl chr 5:63,050,758...63,119,635
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 ISO (MGI:MGI:3766844|PMID:17878231)
(PMID:17878231)
RGD PMID:17878231 MGI:MGI:3766844 NCBI chr 8:124,310,288...124,399,345
Ensembl chr 8:124,312,754...124,399,494
JBrowse link
cellular response to cholesterol term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aacs acetoacetyl-CoA synthetase IEP 25-hydroxycholesterol RGD PMID:3663886 RGD:2326225 NCBI chr12:36,512,393...36,555,694
Ensembl chr12:36,512,393...36,555,694
JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 IEP RGD PMID:15907796, PMID:17526932 RGD:1598535, RGD:2308820 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Apoe apolipoprotein E IEP RGD PMID:21169230 RGD:6904144 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Ces1d carboxylesterase 1D ISO (PMID:18762277) RGD PMID:18762277 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 IDA PMID:1694852 UniProt PMID:1694852 RGD:70534 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Dag1 dystroglycan 1 IEP RGD PMID:22613990 RGD:11541063 NCBI chr 8:116,980,501...116,993,182
Ensembl chr 8:116,980,497...116,993,193
JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:17761367)
Ensembl
UniProt
RGD
PMID:17761367 GO_REF:0000024, GO_REF:0000107 NCBI chr17:42,085,027...42,131,344
Ensembl chr17:42,085,028...42,127,678
JBrowse link
G Gramd1a GRAM domain containing 1A ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:MGI:6242147|PMID:30220461)
UniProt
Ensembl
RGD
PMID:30220461 GO_REF:0000024, GO_REF:0000107, MGI:MGI:6242147 NCBI chr 1:89,563,982...89,590,406
Ensembl chr 1:89,563,976...89,590,490
JBrowse link
G Gramd1b GRAM domain containing 1B ISO (MGI:MGI:6242147|PMID:30220461) RGD PMID:30220461 MGI:MGI:6242147 NCBI chr 8:44,160,634...44,399,110
Ensembl chr 8:44,165,367...44,327,551
JBrowse link
G Gramd1c GRAM domain containing 1C ISO (MGI:MGI:6242147|PMID:30220461) RGD PMID:30220461 MGI:MGI:6242147 NCBI chr11:61,609,370...61,659,355
NCBI chr11:62,580,983...62,634,961
Ensembl chr11:61,605,937...62,634,803
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 IEP 24S-hydroxycholesterol RGD PMID:18303831 RGD:2326114 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G Inhba inhibin subunit beta A IDA PMID:19464342 UniProt PMID:19464342 RGD:8554083 NCBI chr17:51,894,869...51,919,998
Ensembl chr17:51,898,217...51,912,496
JBrowse link
G Inhbb inhibin subunit beta B IDA PMID:19464342 UniProt PMID:19464342 RGD:8554083 NCBI chr13:35,436,532...35,442,222
Ensembl chr13:35,436,532...35,442,222
JBrowse link
G Lrp6 LDL receptor related protein 6 ISO (PMID:16890161) RGD PMID:16890161 NCBI chr 4:168,194,054...168,323,962
Ensembl chr 4:168,194,927...168,323,751
JBrowse link
G Lrp8 LDL receptor related protein 8 IEP RGD PMID:19414061 RGD:2324627 NCBI chr 5:127,404,348...127,476,636
Ensembl chr 5:127,404,450...127,476,641
JBrowse link
G Mlc1 modulator of VRAC current 1 IDA PMID:19931615 UniProt PMID:19931615 RGD:2326037 NCBI chr 7:129,949,984...129,970,314
Ensembl chr 7:129,949,967...129,970,550
JBrowse link
G Nfe2l1 nuclear factor, erythroid 2-like 1 ISO MGI:MGI:6101514 (MGI:MGI:6101031|PMID:29149604) RGD PMID:29149604 MGI:MGI:6101031 NCBI chr10:84,686,762...84,699,313
Ensembl chr10:84,682,460...84,698,886
JBrowse link
G Osbpl7 oxysterol binding protein-like 7 ISO (PMID:21669198) RGD PMID:21669198 NCBI chr10:84,986,330...85,003,947
Ensembl chr10:84,986,328...85,004,562
JBrowse link
G Ptch1 patched 1 ISO (PMID:11278759)
(PMID:21931618)
RGD PMID:11278759, PMID:21931618 NCBI chr17:1,032,242...1,085,885
Ensembl chr17:1,029,048...1,093,873
JBrowse link
G Scp2 sterol carrier protein 2 IEP RGD PMID:8847489, PMID:7989577 RGD:9850161, RGD:9850255 NCBI chr 5:127,647,934...127,735,703
Ensembl chr 5:127,620,274...127,735,739
JBrowse link
G Smo smoothened, frizzled class receptor ISO
IEA
(PMID:21931618)
GO_REF:0000107
RGD
Ensembl
PMID:21931618 GO_REF:0000107 NCBI chr 4:57,019,941...57,041,779
Ensembl chr 4:57,019,941...57,042,770
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    response to stimulus 10583
      response to chemical 6343
        response to oxygen-containing compound 2344
          response to sterol 44
            response to cholesterol 38
              cellular response to cholesterol 21
Path 2
Term Annotations click to browse term
  biological_process 20027
    response to stimulus 10583
      response to chemical 6343
        response to organic substance 3865
          response to lipid 1388
            response to sterol 44
              response to cholesterol 38
                cellular response to cholesterol 21
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.