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Term:nuclear pore transmembrane ring
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Accession:GO:0070762 term browser browse the term
Definition:A subcomplex of the nuclear pore complex (NPC) that spans the nuclear membrane and anchors the NPC to the nuclear envelope. In S. cerevisiae, the transmembrane ring is composed of Pom152p, Pom34p, and Ndc1p. In vertebrates, it is composed of Gp210, Ndc1, and Pom121. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometime referred to as the Ndc1 complex.
Synonyms:exact_synonym: NDC1 complex;   NDC1 subcomplex

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nuclear pore transmembrane ring term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G NDC1 NDC1 transmembrane nucleoporin JBrowse link 5 55,161,079 55,207,969 RGD:13508589

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Path 1
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  cellular_component 16226
    protein-containing complex 5104
      nuclear pore transmembrane ring 1
Path 2
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  cellular_component 16226
    cellular anatomical entity 16058
      organelle 11222
        membrane-bounded organelle 9920
          intracellular membrane-bounded organelle 9141
            nucleus 6261
              nuclear envelope 412
                nuclear pore 59
                  nuclear pore transmembrane ring 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.