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Term:nuclear pore transmembrane ring
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Accession:GO:0070762 term browser browse the term
Definition:A subcomplex of the nuclear pore complex (NPC) that spans the nuclear membrane and anchors the NPC to the nuclear envelope. In S. cerevisiae, the transmembrane ring is composed of Pom152p, Pom34p, and Ndc1p. In vertebrates, it is composed of Gp210, Ndc1, and Pom121. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometime referred to as the Ndc1 complex.
Synonyms:exact_synonym: NDC1 complex;   NDC1 subcomplex

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nuclear pore transmembrane ring term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ndc1 NDC1 transmembrane nucleoporin JBrowse link 4 107,368,047 107,416,346 RGD:2290270

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Path 1
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  cellular_component 23077
    protein-containing complex 5480
      nuclear pore transmembrane ring 1
Path 2
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  cellular_component 23077
    cellular anatomical entity 18808
      organelle 12634
        membrane-bounded organelle 11384
          intracellular membrane-bounded organelle 10614
            nucleus 7056
              nuclear envelope 430
                nuclear pore 64
                  nuclear pore transmembrane ring 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.