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Term:nuclear pore transmembrane ring
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Accession:GO:0070762 term browser browse the term
Definition:A subcomplex of the nuclear pore complex (NPC) that spans the nuclear membrane and anchors the NPC to the nuclear envelope. In S. cerevisiae, the transmembrane ring is composed of Pom152p, Pom34p, and Ndc1p. In vertebrates, it is composed of Gp210, Ndc1, and Pom121. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometime referred to as the Ndc1 complex.
Synonyms:exact_synonym: NDC1 complex;   NDC1 subcomplex

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  cellular_component 12054
    protein-containing complex 3839
      nuclear pore transmembrane ring 0
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  cellular_component 12054
    cellular anatomical entity 11885
      organelle 9318
        membrane-bounded organelle 8263
          intracellular membrane-bounded organelle 7550
            nucleus 5193
              nuclear envelope 359
                nuclear pore 43
                  nuclear pore transmembrane ring 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.