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ONTOLOGY REPORT - ANNOTATIONS


Term:peptidyl-lysine 5-dioxygenase activity
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Accession:GO:0070815 term browser browse the term
Definition:Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 5-hydroxy-L-lysine + succinate + CO2.
Synonyms:exact_synonym: peptide-lysine 5-dioxygenase activity;   protein lysine hydroxylase activity
 broad_synonym: lysine hydroxylase activity;   lysine,2-oxoglutarate 5-dioxygenase activity;   lysine-2-oxoglutarate dioxygenase activity;   lysyl hydroxylase activity
 related_synonym: peptidyl-lysine, 2-oxoglutarate: oxygen oxidoreductase activity;   peptidyllysine, 2-oxoglutarate:oxygen 5-oxidoreductase activity


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peptidyl-lysine 5-dioxygenase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jmjd6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase ISS
ISO
GO_REF:0000024
(PMID:19574390), (PMID:22189873)
UniProt
RGD
PMID:19574390, PMID:22189873 GO_REF:0000024 NCBI chr10:105,781,752...105,787,803
Ensembl chr10:105,781,753...105,787,803
JBrowse link
procollagen-lysine 5-dioxygenase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plod1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 IMP
IEA
IBA
ISO
IDA
GO_REF:0000003
PMID:21873635
(PMID:10934207), (PMID:8621606), (PMID:9724729)
UniProt
RGD
PMID:8621606, PMID:9724729, PMID:10934207, PMID:11714250, PMID:21873635, PMID:11714250 GO_REF:0000003, RGD:1599090, RGD:13792537, RGD:1599090 NCBI chr 5:164,720,629...164,747,071
Ensembl chr 5:164,720,587...164,747,083
JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 ISO
IEA
IBA
(PMID:10934207)
GO_REF:0000003
PMID:21873635
RGD
UniProt
PMID:10934207, PMID:21873635 GO_REF:0000003, RGD:13792537 NCBI chr 8:99,977,334...100,059,736
Ensembl chr 8:99,977,334...100,059,736
JBrowse link
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 ISS
ISO
IBA
GO_REF:0000024
(MGI:MGI:3618677|PMID:16467571), (MGI:MGI:6202004|PMID:16447251)
(PMID:10934207), (PMID:18298658), (PMID:9582318), (PMID:9724729)
PMID:21873635
UniProt
RGD
PMID:9582318, PMID:9724729, PMID:10934207, PMID:16447251, PMID:16467571, PMID:18298658, PMID:21873635 GO_REF:0000024, MGI:MGI:3618677, MGI:MGI:6202004, RGD:13792537 NCBI chr12:22,716,421...22,726,982
Ensembl chr12:22,716,423...22,726,982
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20467
    catalytic activity 6067
      catalytic activity, acting on a protein 2312
        peptidyl-lysine 5-dioxygenase activity 4
          procollagen-lysine 5-dioxygenase activity 3
Path 2
Term Annotations click to browse term
  molecular_function 20467
    catalytic activity 6067
      oxidoreductase activity 877
        oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 223
          2-oxoglutarate-dependent dioxygenase activity 50
            peptidyl-lysine 5-dioxygenase activity 4
              procollagen-lysine 5-dioxygenase activity 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.