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ONTOLOGY REPORT - ANNOTATIONS


Term:inclusion body assembly
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Accession:GO:0070841 term browser browse the term
Definition:The aggregation, arrangement and bonding together of a set of components to form an inclusion body.


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inclusion body assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Psap prosaposin IEA
ISO
GO_REF:0000107
MGI:1888378 (MGI:3664385|PMID:9678511)
Ensembl
RGD
PMID:9678511 GO_REF:0000107, MGI:3664385 NCBI chr20:29,831,302...29,856,876
Ensembl chr20:29,831,314...29,856,875
JBrowse link
aggresome assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dlgap1 DLG associated protein 1 IMP PMID:15496675 BHF-UCL PMID:15496675 RGD:8553458 NCBI chr 9:118,277,046...119,159,807
Ensembl chr 9:118,586,179...119,158,196
JBrowse link
G Hdac6 histone deacetylase 6 ISO (PMID:14675537)
MGI:99919 (MGI:3653156|PMID:16810319)
RGD PMID:14675537, PMID:16810319 MGI:3653156 NCBI chr  X:15,295,372...15,316,673
Ensembl chr  X:15,295,473...15,316,671
JBrowse link
G Pmp22 peripheral myelin protein 22 ISO MGI:1856217 (MGI:3574149|PMID:15748170) RGD PMID:15748170 MGI:3574149 NCBI chr10:49,538,588...49,568,583
Ensembl chr10:49,538,588...49,568,583
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISO
ISS
(PMID:14645198)
GO_REF:0000024
RGD
ParkinsonsUK-UCL
PMID:14645198 GO_REF:0000024 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Trim37 tripartite motif-containing 37 ISO (PMID:15885686) RGD PMID:15885686 NCBI chr10:74,436,165...74,568,636
Ensembl chr10:74,436,208...74,568,493
JBrowse link
G Ubd ubiquitin D IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:19033385)
Ensembl
UniProt
RGD
PMID:19033385 GO_REF:0000024, GO_REF:0000107 NCBI chr20:1,876,175...1,878,126
Ensembl chr20:1,876,173...1,897,814
JBrowse link
G Vcp valosin-containing protein ISO MGI:1333752 (MGI:3653156|PMID:16810319) RGD PMID:16810319 MGI:3653156 NCBI chr 5:58,426,548...58,445,953
Ensembl chr 5:58,426,549...58,445,953
JBrowse link
negative regulation of inclusion body assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnaja4 DnaJ heat shock protein family (Hsp40) member A4 ISO (PMID:21231916) RGD PMID:21231916 NCBI chr 8:59,278,262...59,294,003
Ensembl chr 8:59,278,262...59,294,003
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 ISO (PMID:21231916) RGD PMID:21231916 NCBI chr19:24,747,178...24,750,919
Ensembl chr19:24,747,178...24,750,919
JBrowse link
G Dnajb2 DnaJ heat shock protein family (Hsp40) member B2 ISO (PMID:15936278), (PMID:20889486), (PMID:21231916) RGD PMID:15936278, PMID:20889486, PMID:21231916 NCBI chr 9:82,436,453...82,444,669
Ensembl chr 9:82,436,458...82,444,668
JBrowse link
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 ISO (PMID:20889486), (PMID:21231916) RGD PMID:20889486, PMID:21231916 NCBI chr 4:2,711,329...2,774,969
Ensembl chr 4:2,711,385...2,774,890
JBrowse link
G Dnajb8 DnaJ heat shock protein family (Hsp40) member B8 ISO (PMID:21231916) RGD PMID:21231916 NCBI chr 4:120,156,640...120,159,708
Ensembl chr 4:120,156,659...120,159,265
JBrowse link
G Hsf1 heat shock transcription factor 1 IMP RGD PMID:22216146 RGD:10402367 NCBI chr 7:117,538,523...117,565,478
Ensembl chr 7:117,538,523...117,565,478
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A ISO (PMID:15603737), (PMID:21231916) RGD PMID:15603737, PMID:21231916 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B ISO (PMID:15603737), (PMID:21231916) RGD PMID:15603737, PMID:21231916 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 ISO (PMID:21231916) RGD PMID:21231916 NCBI chr 6:99,433,575...99,436,288
Ensembl chr 6:99,433,550...99,436,289
JBrowse link
G Sacs sacsin molecular chaperone ISO (PMID:19208651) RGD PMID:19208651 NCBI chr15:41,448,078...41,530,412
Ensembl chr15:41,448,064...41,530,398
JBrowse link
negative regulation of neurofibrillary tangle assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sorl1 sortilin related receptor 1 ISO (MGI:5569468|PMID:22986780) RGD PMID:22986780 MGI:5569468 NCBI chr 8:46,228,077...46,287,171 JBrowse link
positive regulation of inclusion body assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc34 cell division cycle 34, ubiqiutin conjugating enzyme IMP RGD PMID:12401444 RGD:2316159 NCBI chr 7:12,899,957...12,905,339
Ensembl chr 7:12,899,958...12,905,339
JBrowse link
G Hap1 huntingtin-associated protein 1 IDA PMID:9798945 UniProt PMID:9798945 RGD:10047369 NCBI chr10:88,257,975...88,266,210
Ensembl chr10:88,257,976...88,266,210
JBrowse link
G Hsf1 heat shock transcription factor 1 IMP RGD PMID:22216146 RGD:10402367 NCBI chr 7:117,538,523...117,565,478
Ensembl chr 7:117,538,523...117,565,478
JBrowse link
G Psmc5 proteasome 26S subunit, ATPase 5 IMP RGD PMID:18986984 RGD:7242199 NCBI chr10:94,445,877...94,451,811
Ensembl chr10:94,445,877...94,451,811
JBrowse link
G Psmc6 proteasome 26S subunit, ATPase 6 IMP RGD PMID:18986984 RGD:7242199 NCBI chr15:19,667,453...19,688,916
Ensembl chr15:19,667,453...19,688,914
JBrowse link
positive regulation of neurofibrillary tangle assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E ISO (PMID:24154541) RGD PMID:24154541 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Clu clusterin ISO
IEA
ISS
(PMID:15897157)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
Alzheimers_University_of_Toronto
PMID:15897157 GO_REF:0000024, GO_REF:0000107 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
regulation of inclusion body assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag5 BAG cochaperone 5 IDA
IBA
ISO
PMID:15603737
PMID:21873635
(PMID:15603737)
RGD PMID:15603737, PMID:15603737, PMID:21873635 RGD:8553807, RGD:13792537 NCBI chr 6:136,180,640...136,185,651
Ensembl chr 6:136,182,006...136,185,651
JBrowse link
G Bag5l1 BCL2-associated athanogene 5-like 1 IDA
IBA
PMID:15603737
PMID:21873635
BHF-UCL
GO_Central
PMID:15603737, PMID:21873635 RGD:8553807, RGD:13792537 NCBI chr 6:136,274,351...136,279,414
Ensembl chr 6:136,182,006...136,185,651
Ensembl chr 6:136,182,006...136,185,651
JBrowse link
G Sncaip synuclein, alpha interacting protein ISO
ISS
(PMID:15603737)
GO_REF:0000024
RGD
ParkinsonsUK-UCL
PMID:15603737 GO_REF:0000024 NCBI chr18:47,739,284...47,877,679
Ensembl chr18:47,739,140...47,877,676
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    cellular process 18792
      cellular component organization or biogenesis 6789
        cellular component biogenesis 3291
          cellular component assembly 2983
            inclusion body assembly 28
              Lewy body formation + 0
              aggresome assembly 7
              negative regulation of inclusion body assembly + 11
              neurofibrillary tangle assembly + 3
              positive regulation of inclusion body assembly + 7
              regulation of inclusion body assembly + 20
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.