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ONTOLOGY REPORT - ANNOTATIONS


Term:response to epidermal growth factor
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Accession:GO:0070849 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.
Synonyms:exact_synonym: response to EGF stimulus;   response to epidermal growth factor stimulus


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response to epidermal growth factor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl1 achaete-scute family bHLH transcription factor 1 ISO RGD PMID:9473334 RGD:2314149 NCBI chrNW_004955405:37,941,243...37,943,641 JBrowse link
G Igf1 insulin like growth factor 1 ISO RGD PMID:2003595 RGD:12910130 NCBI chrNW_004955405:37,505,830...37,582,152 JBrowse link
G Il1r1 interleukin 1 receptor type 1 ISO RGD PMID:9233842 RGD:8662880 NCBI chrNW_004955470:7,685,498...7,703,374 JBrowse link
G Mapk1 mitogen-activated protein kinase 1 ISO (PMID:18794356) UniProtKB PMID:18794356 NCBI chrNW_004955442:17,284,232...17,380,026 JBrowse link
G Mapk3 mitogen-activated protein kinase 3 ISO (PMID:18794356), (PMID:21968647) UniProtKB PMID:18794356, PMID:21968647 NCBI chrNW_004955493:6,870,699...6,876,836 JBrowse link
G Serpine1 serpin family E member 1 ISO RGD PMID:1333984 RGD:8547845 NCBI chrNW_004955456:16,147,523...16,157,040 JBrowse link
G Sftpb surfactant protein B ISO RGD PMID:19781387 RGD:4143468 NCBI chrNW_004955424:1,849,313...1,858,087 JBrowse link
G Tpr translocated promoter region, nuclear basket protein ISO (PMID:18794356) UniProtKB PMID:18794356 NCBI chrNW_004955406:24,742,525...24,805,989 JBrowse link
cellular response to epidermal growth factor stimulus term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actr3 actin related protein 3 ISO RGD PMID:10209028 RGD:2306208 NCBI chrNW_004955459:15,216,914...15,284,013 JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO (MGI:MGI:5292318|PMID:21712384) UniProtKB PMID:21712384 MGI:MGI:5292318 NCBI chrNW_004955538:3,208,711...3,224,386 JBrowse link
G Arpc2 actin related protein 2/3 complex subunit 2 ISO RGD PMID:15252126 RGD:2306210 NCBI chrNW_004955453:15,117,978...15,145,895 JBrowse link
G Bag4 BAG cochaperone 4 ISO (MGI:MGI:5292318|PMID:21712384) UniProtKB PMID:21712384 MGI:MGI:5292318 NCBI chrNW_004955463:13,788,852...13,824,135 JBrowse link
G Baiap2 BAR/IMD domain containing adaptor protein 2 ISO RGD PMID:17855387 RGD:2306203 NCBI chrNW_004955506:1,868,624...1,936,786 JBrowse link
G Becn1 beclin 1 ISO RGD PMID:20539009 RGD:6483081 NCBI chrNW_004955451:16,616,595...16,625,731 JBrowse link
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase ISO RGD PMID:10659854 RGD:2303528 NCBI chrNW_004955469:9,203,433...9,227,526 JBrowse link
G Cbl Cbl proto-oncogene ISO RGD PMID:22203672 RGD:11576305 NCBI chrNW_004955412:20,307,011...20,388,539 JBrowse link
G Cfl1 cofilin 1 ISO RGD PMID:23704350, PMID:26324884 RGD:11568705, RGD:11570555 NCBI chrNW_004955422:19,479,181...19,482,571 JBrowse link
G Cflar CASP8 and FADD like apoptosis regulator ISO RGD PMID:16033771 RGD:11341689 NCBI chrNW_004955403:415,092...442,214 JBrowse link
G Col1a1 collagen type I alpha 1 chain ISO RGD PMID:2016852 RGD:2316227 NCBI chrNW_004955451:11,468,156...11,484,410 JBrowse link
G Dab2 DAB adaptor protein 2 ISO PMID:12473651 UniProt PMID:12473651 RGD:8553624 NCBI chrNW_004955426:23,852,752...23,883,030 JBrowse link
G Dab2ip DAB2 interacting protein ISO PMID:11812785 BHF-UCL PMID:11812785 RGD:632628 NCBI chrNW_004955419:6,229,437...6,416,619 JBrowse link
G Dusp22 dual specificity phosphatase 22 ISO (PMID:20018849) ARUK-UCL PMID:20018849 NCBI chrNW_004955465:12,551,063...12,597,386 JBrowse link
G Dusp3 dual specificity phosphatase 3 ISO (MGI:MGI:6101044|PMID:28759036)
(PMID:28759036)
BHF-UCL PMID:28759036 MGI:MGI:6101044 NCBI chrNW_004955451:17,064,739...17,069,964 JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 ISO (PMID:9852145) UniProtKB PMID:9852145 NCBI chrNW_004955493:8,661,317...8,663,190 JBrowse link
G Egfr epidermal growth factor receptor ISO PMID:20639532 UniProt PMID:20639532 RGD:8553583 NCBI chrNW_004955456:321,222...456,431 JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO (PMID:27134172) UniProtKB PMID:27134172 NCBI chrNW_004955451:14,442,816...14,456,009 JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 ISO (MGI:MGI:82360|PMID:8702723) MGI PMID:8702723 MGI:MGI:82360 NCBI chrNW_004955457:3,177,905...4,236,152 JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 ISO RGD PMID:15556944 RGD:9685545 NCBI chrNW_004955486:4,941,143...4,955,693 JBrowse link
G Garem1 GRB2 associated regulator of MAPK1 subtype 1 ISO (PMID:19509291) UniProtKB PMID:19509291 NCBI chrNW_004955402:19,469,652...19,663,654 JBrowse link
G Git1 GIT ArfGAP 1 ISO RGD PMID:18523162 RGD:13513208 NCBI chrNW_004955481:3,671,728...3,681,279 JBrowse link
G Grk2 G protein-coupled receptor kinase 2 ISO RGD PMID:24018045 RGD:13792711 NCBI chrNW_004955422:18,173,438...18,192,357 JBrowse link
G Gstp1 glutathione S-transferase pi 1 ISO RGD PMID:1908848 RGD:2317845 NCBI chrNW_004955422:17,914,228...17,916,918 JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 ISO RGD PMID:3062579 RGD:10041005 NCBI chrNW_004955458:1,530,163...1,536,874 JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein ISO RGD PMID:7623812 RGD:9686118 NCBI chrNW_004955422:29,337,969...29,339,178 JBrowse link
G Igfals insulin like growth factor binding protein acid labile subunit ISO RGD PMID:8070348 RGD:12911020 NCBI chrNW_004955442:15,469,602...15,482,115 JBrowse link
G Inpp5k inositol polyphosphate-5-phosphatase K ISO (PMID:21712384) UniProtKB PMID:21712384 NCBI chrNW_004955481:1,651,422...1,674,402 JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 ISO (PMID:17563371), (PMID:26242911)
(MGI:MGI:5430891|PMID:17563371)
ARUK-UCL
BHF-UCL
PMID:17563371, PMID:26242911 MGI:MGI:5430891 NCBI chrNW_004955416:14,558,628...14,652,031 JBrowse link
G Ireb2 iron responsive element binding protein 2 ISO RGD PMID:10889193 RGD:12910555 NCBI chrNW_004955450:852,554...898,908 JBrowse link
G Knstrn kinetochore localized astrin (SPAG5) binding protein ISO (PMID:26242911) ARUK-UCL PMID:26242911 NCBI chrNW_004955416:7,311,483...7,322,272 JBrowse link
G Mars1 methionyl-tRNA synthetase 1 ISO (PMID:10791971) CAFA PMID:10791971 NCBI chrNW_004955458:5,215,853...5,233,037 JBrowse link
G Mcm7 minichromosome maintenance complex component 7 ISO RGD PMID:19821535 RGD:2316313 NCBI chrNW_004955573:763,358...770,782 JBrowse link
G Med1 mediator complex subunit 1 ISO (PMID:16314496) UniProtKB PMID:16314496 NCBI chrNW_004955451:14,204,326...14,237,809 JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming ISO RGD PMID:11769575 RGD:2324971 NCBI chrNW_004955476:11,061,405...11,084,294 JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor ISO RGD PMID:7524476 RGD:10059620 NCBI chrNW_004955461:2,714,022...2,718,872 JBrowse link
G Ncl nucleolin ISO (MGI:MGI:82360|PMID:8702723) MGI PMID:8702723 MGI:MGI:82360 NCBI chrNW_004955453:4,154,627...4,164,253 JBrowse link
G Pax2 paired box 2 ISO RGD PMID:11262416 RGD:2316756 NCBI chrNW_004955485:9,351,913...9,430,607 JBrowse link
G Pde8a phosphodiesterase 8A ISO (MGI:MGI:5484722|PMID:23509299)
(PMID:23509299)
UniProtKB PMID:23509299 MGI:MGI:5484722 NCBI chrNW_004955416:14,063,117...14,204,297 JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase 1 ISO (PMID:22454520) BHF-UCL PMID:22454520 NCBI chrNW_004955442:14,685,089...14,772,870 JBrowse link
G Plcg1 phospholipase C gamma 1 ISO (PMID:17229814)
(PMID:22454520)
UniProtKB
BHF-UCL
PMID:17229814, PMID:22454520 NCBI chrNW_004955445:15,787,496...15,823,859 JBrowse link
G Ppp1r9b protein phosphatase 1 regulatory subunit 9B ISO RGD PMID:10620493 RGD:10002737 NCBI chrNW_004955451:11,516,548...11,530,263 JBrowse link
G Ptpn11 protein tyrosine phosphatase non-receptor type 11 ISO (PMID:28074573) UniProtKB PMID:28074573 NCBI chrNW_004955482:8,934,734...9,031,230 JBrowse link
G Ptpn12 protein tyrosine phosphatase non-receptor type 12 ISO (PMID:27134172) UniProtKB PMID:27134172 NCBI chrNW_004955410:7,556,283...7,599,170 JBrowse link
G Rasa1 RAS p21 protein activator 1 ISO RGD PMID:2005883 RGD:10002731 NCBI chrNW_004955418:23,807,740...23,897,699 JBrowse link
G Snai2 snail family transcriptional repressor 2 ISO (PMID:18716062) BHF-UCL PMID:18716062 NCBI chrNW_004955454:8,759,860...8,763,603 JBrowse link
G Snx6 sorting nexin 6 ISO RGD PMID:18523162 RGD:13513208 NCBI chrNW_004955409:26,323,940...26,353,675 JBrowse link
G Sox9 SRY-box transcription factor 9 ISO (MGI:MGI:5285125|PMID:21512138) UniProtKB PMID:21512138 MGI:MGI:5285125 NCBI chrNW_004955478:941,684...945,563 JBrowse link
G Stat5b signal transducer and activator of transcription 5B ISO PMID:20639532 UniProt PMID:20639532 RGD:8553583 NCBI chrNW_004955451:16,253,645...16,295,337 JBrowse link
G Syap1 synapse associated protein 1 ISO (PMID:23300339)
(MGI:MGI:6114863|PMID:23300339)
UniProtKB PMID:23300339 MGI:MGI:6114863 NCBI chrNW_004955519:1,556,376...1,575,144 JBrowse link
G Tdgf1 teratocarcinoma-derived growth factor 1 ISO (PMID:17720976) UniProtKB PMID:17720976 NCBI chrNW_004955420:25,476,975...25,479,969 JBrowse link
G Vil1 villin 1 ISO (PMID:17229814) UniProtKB PMID:17229814 NCBI chrNW_004955453:14,935,450...14,961,011 JBrowse link
G Zfp36 ZFP36 ring finger protein ISO (PMID:20166898) UniProtKB PMID:20166898 NCBI chrNW_004955468:152,744...155,140 JBrowse link
G Zfp36l1 ZFP36 ring finger protein like 1 ISO (PMID:20166898) UniProtKB PMID:20166898 NCBI chrNW_004955466:1,541,367...1,546,617 JBrowse link
G Zfp36l2 ZFP36 ring finger protein like 2 ISO (PMID:20166898) UniProtKB PMID:20166898 NCBI chrNW_004955441:10,467,608...10,469,885 JBrowse link
G Zpr1 ZPR1 zinc finger ISO (PMID:9852145) UniProtKB PMID:9852145 NCBI chrNW_004955412:18,117,957...18,127,552 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11857
    response to stimulus 6353
      response to endogenous stimulus 1681
        response to epidermal growth factor 64
          cellular response to epidermal growth factor stimulus 56
Path 2
Term Annotations click to browse term
  biological_process 11857
    response to stimulus 6353
      response to chemical 3715
        response to organic substance 2997
          response to growth factor 720
            response to epidermal growth factor 64
              cellular response to epidermal growth factor stimulus 56
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.