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ONTOLOGY REPORT - ANNOTATIONS


Term:response to epidermal growth factor
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Accession:GO:0070849 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.
Synonyms:exact_synonym: response to EGF stimulus;   response to epidermal growth factor stimulus


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response to epidermal growth factor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASCL1 achaete-scute family bHLH transcription factor 1 ISO RGD PMID:9473334 RGD:2314149 NCBI chr15:41,694,021...41,696,933
Ensembl chr15:41,694,269...41,695,391
JBrowse link
G IGF1 insulin like growth factor 1 ISO RGD PMID:2003595 RGD:12910130 NCBI chr15:41,203,320...41,275,964
Ensembl chr15:41,202,518...41,275,794
JBrowse link
G IL1R1 interleukin 1 receptor type 1 ISO RGD PMID:9233842 RGD:8662880 NCBI chr10:40,825,986...40,897,898
Ensembl chr10:40,827,377...40,897,596
JBrowse link
G LOC490770 acyl-coenzyme A thioesterase 1 ISO murine EGF RGD PMID:18388199 RGD:2315857 NCBI chr 8:46,851,109...46,873,354
Ensembl chr 8:46,852,880...46,911,640
JBrowse link
G LOC610540 pulmonary surfactant-associated protein A-like ISO RGD PMID:19781387 RGD:4143468 NCBI chr 4:29,430,139...29,434,640 JBrowse link
G MAPK1 mitogen-activated protein kinase 1 IEA Ensembl GO_REF:0000107 NCBI chr26:31,013,607...31,132,998
Ensembl chr26:31,013,607...31,132,998
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 ISO (PMID:18794356), (PMID:21968647) UniProtKB PMID:18794356, PMID:21968647 NCBI chr 6:18,109,184...18,115,728
Ensembl chr 6:18,109,222...18,114,425
JBrowse link
G SERPINE1 serpin family E member 1 ISO RGD PMID:1333984 RGD:8547845 NCBI chr 6:8,719,547...8,727,160
Ensembl chr 6:8,720,825...8,726,301
JBrowse link
G SFTPB surfactant protein B ISO RGD PMID:19781387 RGD:4143468 NCBI chr17:39,419,305...39,428,513
Ensembl chr17:39,386,584...39,426,229
JBrowse link
G TPR translocated promoter region, nuclear basket protein IEA Ensembl GO_REF:0000107 NCBI chr 7:19,376,951...19,442,368
Ensembl chr 7:19,376,975...19,442,303
JBrowse link
cellular response to epidermal growth factor stimulus term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTR3 actin related protein 3 ISO RGD PMID:10209028 RGD:2306208 NCBI chr19:35,097,968...35,133,330
Ensembl chr19:35,098,639...35,169,724
JBrowse link
G AKT1 AKT serine/threonine kinase 1 IEA Ensembl GO_REF:0000107 NCBI chr 8:72,317,399...72,335,686
Ensembl chr 8:72,317,869...72,335,193
JBrowse link
G ARPC2 actin related protein 2/3 complex subunit 2 ISO RGD PMID:15252126 RGD:2306210 NCBI chr37:24,914,389...24,935,998
Ensembl chr37:24,914,642...24,935,824
JBrowse link
G BAG4 BAG cochaperone 4 IEA Ensembl GO_REF:0000107 NCBI chr16:27,270,947...27,304,178
Ensembl chr16:27,273,848...27,303,786
JBrowse link
G BAIAP2 BAR/IMD domain containing adaptor protein 2 ISO RGD PMID:17855387 RGD:2306203 NCBI chr 9:923,519...992,254
Ensembl chr 9:923,493...981,923
JBrowse link
G BECN1 beclin 1 ISO RGD PMID:20539009 RGD:6483081 NCBI chr 9:20,204,203...20,215,081
Ensembl chr 9:20,204,220...20,214,236
JBrowse link
G CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase ISO RGD PMID:10659854 RGD:2303528 NCBI chr17:21,198,839...21,221,897
Ensembl chr17:21,197,826...21,221,635
JBrowse link
G CBL Cbl proto-oncogene ISO RGD PMID:22203672 RGD:11576305 NCBI chr 5:14,600,409...14,676,974
Ensembl chr 5:14,607,013...14,676,956
JBrowse link
G CFL1 cofilin 1 ISO RGD PMID:23704350, PMID:26324884 RGD:11568705, RGD:11570555 NCBI chr18:51,404,649...51,408,240
Ensembl chr18:51,401,659...51,408,212
JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator ISO RGD PMID:16033771 RGD:11341689 NCBI chr37:10,268,407...10,307,803
Ensembl chr37:10,268,582...10,345,095
JBrowse link
G COL1A1 collagen type I alpha 1 chain ISO RGD PMID:2016852 RGD:2316227 NCBI chr 9:26,183,852...26,199,927
Ensembl chr 9:26,183,852...26,199,927
JBrowse link
G DAB2IP DAB2 interacting protein ISO PMID:11812785 BHF-UCL PMID:11812785 RGD:632628 NCBI chr 9:60,725,887...60,918,242
Ensembl chr 9:60,726,809...60,918,139
JBrowse link
G DUSP22 dual specificity phosphatase 22 IEA Ensembl GO_REF:0000107 NCBI chr35:678,320...733,225
Ensembl chr35:678,155...732,397
JBrowse link
G DUSP3 dual specificity phosphatase 3 IEA Ensembl GO_REF:0000107 NCBI chr 9:19,518,302...19,531,000
Ensembl chr 9:19,518,746...19,527,624
JBrowse link
G EEF1A1 eukaryotic translation elongation factor 1 alpha 1 IEA Ensembl GO_REF:0000107 NCBI chr12:35,576,576...35,581,339
Ensembl chr12:35,576,576...35,581,230
JBrowse link
G EGFR epidermal growth factor receptor ISO PMID:20639532 UniProt PMID:20639532 RGD:8553583 NCBI chr18:5,983,669...6,044,092
Ensembl chr18:5,982,770...6,042,631
JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 ISS
IEA
UniProtKB
Ensembl
GO_REF:0000024, GO_REF:0000107 NCBI chr 9:22,760,373...22,785,367
Ensembl chr 9:22,759,256...22,785,294
JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 IEA Ensembl GO_REF:0000107 NCBI chr37:19,029,647...20,134,576
Ensembl chr37:19,037,217...20,134,426
JBrowse link
G ERRFI1 ERBB receptor feedback inhibitor 1 ISO RGD PMID:15556944 RGD:9685545 NCBI chr 5:61,621,964...61,636,152
Ensembl chr 5:61,622,550...61,636,148
JBrowse link
G GAREM1 GRB2 associated regulator of MAPK1 subtype 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:57,158,005...57,423,643
Ensembl chr 7:57,295,070...57,419,252
JBrowse link
G GIT1 GIT ArfGAP 1 ISO RGD PMID:18523162 RGD:13513208 NCBI chr 9:43,676,707...43,686,566
Ensembl chr 9:43,677,899...43,693,177
JBrowse link
G GRK2 G protein-coupled receptor kinase 2 ISO RGD PMID:24018045 RGD:13792711 NCBI chr18:50,148,566...50,167,422
Ensembl chr18:50,148,598...50,167,428
JBrowse link
G GSTP1 glutathione S-transferase pi 1 ISO RGD PMID:1908848 RGD:2317845 NCBI chr18:49,905,161...49,908,182
Ensembl chr18:49,905,161...49,908,182
JBrowse link
G HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 ISO RGD PMID:3062579 RGD:10041005 NCBI chr27:1,013,459...1,020,083
Ensembl chr27:1,015,868...1,019,891
JBrowse link
G ID1 inhibitor of DNA binding 1, HLH protein ISO RGD PMID:7623812 RGD:9686118 NCBI chr24:21,094,339...21,096,276
Ensembl chr24:21,094,755...21,096,276
JBrowse link
G IGFALS insulin like growth factor binding protein acid labile subunit ISO RGD PMID:8070348 RGD:12911020 NCBI chr 6:39,115,744...39,118,831
Ensembl chr 6:39,114,315...39,119,652
JBrowse link
G INPP5K inositol polyphosphate-5-phosphatase K ISS UniProtKB GO_REF:0000024 NCBI chr 9:45,660,445...45,680,407
Ensembl chr 9:45,660,446...45,680,363
JBrowse link
G IQGAP1 IQ motif containing GTPase activating protein 1 IEA Ensembl GO_REF:0000107 NCBI chr 3:53,683,869...53,791,136
Ensembl chr 3:53,683,791...53,792,186
JBrowse link
G IREB2 iron responsive element binding protein 2 ISO RGD PMID:10889193 RGD:12910555 NCBI chr13:38,398,445...38,441,128
Ensembl chr13:38,400,591...38,441,015
JBrowse link
G KNSTRN kinetochore localized astrin (SPAG5) binding protein IEA Ensembl GO_REF:0000107 NCBI chr30:7,562,738...7,573,514
Ensembl chr30:7,562,807...7,572,950
JBrowse link
G LOC102155289 elongation factor 1-alpha 1 IEA Ensembl GO_REF:0000107 NCBI chr 3:60,899,797...60,901,258
Ensembl chr12:35,576,576...35,581,230
JBrowse link
G MARS1 methionyl-tRNA synthetase 1 IEA Ensembl GO_REF:0000107 NCBI chr10:1,588,503...1,606,752
Ensembl chr10:1,588,875...1,606,750
JBrowse link
G MCM7 minichromosome maintenance complex component 7 ISO RGD PMID:19821535 RGD:2316313 NCBI chr 6:9,492,654...9,499,846
Ensembl chr 6:9,492,573...9,499,855
JBrowse link
G MED1 mediator complex subunit 1 ISS UniProtKB GO_REF:0000024 NCBI chr 9:22,989,257...23,019,350
Ensembl chr 9:22,989,301...23,019,349
JBrowse link
G MUC5AC mucin 5AC, oligomeric mucus/gel-forming ISO RGD PMID:11769575 RGD:2324971 NCBI chr18:45,471,232...45,498,961 JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO RGD PMID:7524476 RGD:10059620 NCBI chr13:25,200,772...25,205,309
Ensembl chr13:25,200,577...25,205,309
JBrowse link
G NCL nucleolin IEA Ensembl GO_REF:0000107 NCBI chr25:43,330,524...43,384,909
Ensembl chr25:43,330,799...43,384,258
JBrowse link
G PAX2 paired box 2 ISO RGD PMID:11262416 RGD:2316756 NCBI chr28:13,442,894...13,519,853
Ensembl chr28:13,442,893...13,532,094
JBrowse link
G PDE8A phosphodiesterase 8A IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 3:54,278,498...54,367,492
Ensembl chr 3:54,128,680...54,367,400
JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 IEA Ensembl GO_REF:0000107 NCBI chr 6:38,426,464...38,506,520
Ensembl chr 6:38,431,600...38,499,295
JBrowse link
G PLCG1 phospholipase C gamma 1 IEA Ensembl GO_REF:0000107 NCBI chr24:29,198,536...29,213,899
Ensembl chr24:29,198,556...29,214,714
JBrowse link
G PPP1R9B protein phosphatase 1 regulatory subunit 9B ISO RGD PMID:10620493 RGD:10002737 NCBI chr 9:26,135,982...26,152,303
Ensembl chr 9:26,137,464...26,151,810
JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 IEA Ensembl GO_REF:0000107 NCBI chr26:9,989,218...10,072,245
Ensembl chr26:9,989,425...10,067,481
JBrowse link
G PTPN12 protein tyrosine phosphatase non-receptor type 12 IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr18:17,608,665...17,692,543
Ensembl chr18:17,607,936...17,692,219
JBrowse link
G RASA1 RAS p21 protein activator 1 ISO RGD PMID:2005883 RGD:10002731 NCBI chr 3:21,068,182...21,177,288
Ensembl chr 3:21,054,930...21,176,757
JBrowse link
G SLC28A1 solute carrier family 28 member 1 IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 3:54,128,172...54,177,544
Ensembl chr 3:54,128,680...54,367,400
JBrowse link
G SNAI2 snail family transcriptional repressor 2 IEA Ensembl GO_REF:0000107 NCBI chr29:1,154,132...1,156,653
Ensembl chr29:1,154,036...1,156,653
JBrowse link
G SNX6 sorting nexin 6 ISO RGD PMID:18523162 RGD:13513208 NCBI chr 8:13,460,676...13,520,282
Ensembl chr 8:13,460,947...13,520,423
JBrowse link
G SOX9 SRY-box transcription factor 9 ISS UniProtKB GO_REF:0000024 NCBI chr 9:8,275,049...8,278,172
Ensembl chr 9:8,275,049...8,278,172
JBrowse link
G STAT5B signal transducer and activator of transcription 5B ISO PMID:20639532 UniProt PMID:20639532 RGD:8553583 NCBI chr 9:20,647,712...20,718,453
Ensembl chr 9:20,691,483...20,716,485
JBrowse link
G SYAP1 synapse associated protein 1 IEA Ensembl GO_REF:0000107 NCBI chr  X:12,869,824...12,902,677
Ensembl chr  X:12,869,932...12,901,258
JBrowse link
G TDGF1 teratocarcinoma-derived growth factor 1 ISO (PMID:17720976) UniProtKB PMID:17720976 NCBI chr20:42,137,939...42,140,590 JBrowse link
G VIL1 villin 1 IEA Ensembl GO_REF:0000107 NCBI chr37:25,065,887...25,090,238
Ensembl chr37:25,065,180...25,090,705
JBrowse link
G ZFP36 ZFP36 ring finger protein ISO (PMID:20166898) UniProtKB PMID:20166898 NCBI chr 1:113,815,972...113,818,093
Ensembl chr 1:113,816,273...113,818,065
JBrowse link
G ZFP36L1 ZFP36 ring finger protein like 1 IEA Ensembl GO_REF:0000107 NCBI chr 8:42,663,287...42,668,665
Ensembl chr 8:42,664,223...42,668,514
JBrowse link
G ZFP36L2 ZFP36 ring finger protein like 2 IEA Ensembl GO_REF:0000107 NCBI chr10:45,746,952...45,751,268
Ensembl chr10:45,748,936...45,751,250
JBrowse link
G ZPR1 ZPR1 zinc finger IEA Ensembl GO_REF:0000107 NCBI chr 5:16,778,803...16,787,493
Ensembl chr 5:16,778,832...16,787,105
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16162
    response to stimulus 8537
      response to endogenous stimulus 1927
        response to epidermal growth factor 67
          cellular response to epidermal growth factor stimulus 57
Path 2
Term Annotations click to browse term
  biological_process 16162
    response to stimulus 8537
      response to chemical 5053
        response to organic substance 3538
          response to growth factor 784
            response to epidermal growth factor 67
              cellular response to epidermal growth factor stimulus 57
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.