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ONTOLOGY REPORT - ANNOTATIONS


Term:response to epidermal growth factor
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Accession:GO:0070849 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.
Synonyms:exact_synonym: response to EGF stimulus;   response to epidermal growth factor stimulus


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response to epidermal growth factor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acot2 acyl-CoA thioesterase 2 ISO murine EGF RGD PMID:18388199 RGD:2315857 NCBI chr12:83,987,861...83,993,877
Ensembl chr12:83,987,861...83,993,873
JBrowse link
G Ascl1 achaete-scute family bHLH transcription factor 1 ISO RGD PMID:9473334 RGD:2314149 NCBI chr10:87,490,819...87,493,660
Ensembl chr10:87,490,819...87,493,660
JBrowse link
G Igf1 insulin-like growth factor 1 ISO RGD PMID:2003595 RGD:12910130 NCBI chr10:87,858,265...87,937,047
Ensembl chr10:87,858,265...87,937,042
JBrowse link
G Il1r1 interleukin 1 receptor, type I ISO RGD PMID:9233842 RGD:8662880 NCBI chr 1:40,222,480...40,316,201
Ensembl chr 1:40,225,080...40,317,257
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr16:16,983,382...17,047,453
Ensembl chr16:16,983,382...17,047,453
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 7:126,759,626...126,765,816
Ensembl chr 7:126,759,601...126,765,819
JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 ISO RGD PMID:1333984 RGD:8547845 NCBI chr 5:137,061,504...137,072,272
Ensembl chr 5:137,061,504...137,072,268
JBrowse link
G Sftpa1 surfactant associated protein A1 ISO RGD PMID:19781387 RGD:4143468 NCBI chr14:41,131,788...41,136,373
Ensembl chr14:41,131,782...41,136,452
JBrowse link
G Sftpb surfactant associated protein B ISO RGD PMID:19781387 RGD:4143468 NCBI chr 6:72,304,610...72,314,373
Ensembl chr 6:72,304,610...72,314,371
JBrowse link
G Tpr translocated promoter region, nuclear basket protein ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 1:150,392,802...150,449,935
Ensembl chr 1:150,392,838...150,449,935
JBrowse link
cellular response to epidermal growth factor stimulus term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actr3 ARP3 actin-related protein 3 ISO RGD PMID:10209028 RGD:2306208 NCBI chr 1:125,392,905...125,435,727
Ensembl chr 1:125,392,905...125,435,727
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 IDA (MGI:MGI:5292318|PMID:21712384) UniProtKB PMID:21712384 MGI:MGI:5292318 NCBI chr12:112,653,821...112,674,884
Ensembl chr12:112,653,821...112,674,884
JBrowse link
G Arpc2 actin related protein 2/3 complex, subunit 2 ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr 1:74,236,490...74,268,209
Ensembl chr 1:74,236,084...74,268,209
JBrowse link
G Bag4 BCL2-associated athanogene 4 IDA (MGI:MGI:5292318|PMID:21712384) UniProtKB PMID:21712384 MGI:MGI:5292318 NCBI chr 8:25,764,538...25,785,209
Ensembl chr 8:25,764,538...25,785,287
JBrowse link
G Baiap2 brain-specific angiogenesis inhibitor 1-associated protein 2 ISO RGD PMID:17855387 RGD:2306203 NCBI chr11:119,939,916...120,006,782
Ensembl chr11:119,942,763...120,006,782
JBrowse link
G Becn1 beclin 1, autophagy related ISO RGD PMID:20539009 RGD:6483081 NCBI chr11:101,288,258...101,302,286
Ensembl chr11:101,285,952...101,302,286
JBrowse link
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase ISO RGD PMID:10659854 RGD:2303528 NCBI chr 5:31,054,620...31,078,479
Ensembl chr 5:31,054,780...31,078,479
JBrowse link
G Cbl Casitas B-lineage lymphoma ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr 9:44,142,976...44,234,259
Ensembl chr 9:44,142,976...44,234,049
JBrowse link
G Cfl1 cofilin 1, non-muscle ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr19:5,490,455...5,494,031
Ensembl chr19:5,490,455...5,495,201
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator ISO RGD PMID:16033771 RGD:11341689 NCBI chr 1:58,711,311...58,758,884
Ensembl chr 1:58,711,508...58,758,884
JBrowse link
G Col1a1 collagen, type I, alpha 1 ISO RGD PMID:2016852 RGD:2316227 NCBI chr11:94,936,224...94,953,042
Ensembl chr11:94,936,224...94,953,042
JBrowse link
G Dab2 disabled 2, mitogen-responsive phosphoprotein ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr15:6,299,788...6,440,715
Ensembl chr15:6,299,788...6,440,712
JBrowse link
G Dab2ip disabled 2 interacting protein ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr 2:35,558,446...35,730,994
Ensembl chr 2:35,558,266...35,730,994
JBrowse link
G Dusp22 dual specificity phosphatase 22 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr13:30,660,059...30,711,232
Ensembl chr13:30,659,999...30,711,231
JBrowse link
G Dusp3 dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) ISO
IMP
(MGI:MGI:6101044|PMID:28759036) MGI
BHF-UCL
PMID:28759036 GO_REF:0000096, MGI:MGI:4834177, MGI:MGI:6101044 NCBI chr11:101,971,141...101,987,013
Ensembl chr11:101,971,143...101,987,013
JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 9:78,478,453...78,481,724
Ensembl chr 9:78,478,449...78,489,151
JBrowse link
G Egfr epidermal growth factor receptor ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr11:16,752,203...16,913,907
Ensembl chr11:16,752,203...16,918,158
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr11:98,412,484...98,437,716
Ensembl chr11:98,412,470...98,437,716
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 IDA (MGI:MGI:82360|PMID:8702723) MGI PMID:8702723 MGI:MGI:82360 NCBI chr 1:68,031,884...69,108,576
Ensembl chr 1:68,032,186...69,108,059
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 ISO RGD PMID:15556944 RGD:9685545 NCBI chr 4:150,853,796...150,868,889
Ensembl chr 4:150,853,919...150,868,892
JBrowse link
G Foxc1 forkhead box C1 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr13:31,806,646...31,810,635
Ensembl chr13:31,806,633...31,812,476
JBrowse link
G Garem1 GRB2 associated regulator of MAPK1 subtype 1 ISO
IBA
(MGI:MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096, MGI:MGI:4834177, MGI:MGI:6201960 NCBI chr18:21,127,342...21,300,139
Ensembl chr18:21,127,201...21,300,138
JBrowse link
G Git1 GIT ArfGAP 1 ISO MGI GO_REF:0000096, MGI:MGI:4417868 NCBI chr11:77,493,288...77,507,774
Ensembl chr11:77,493,562...77,507,786
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 ISO MGI GO_REF:0000096, MGI:MGI:4417868 NCBI chr19:4,285,999...4,306,222
Ensembl chr19:4,286,001...4,306,222
JBrowse link
G Gstp1 glutathione S-transferase, pi 1 ISO RGD PMID:1908848 RGD:2317845 NCBI chr19:4,035,411...4,037,912
Ensembl chr19:4,035,407...4,037,985
JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 ISO RGD PMID:3062579 RGD:10041005 NCBI chr15:103,239,943...103,246,698
Ensembl chr15:103,240,432...103,246,692
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein ISO RGD PMID:7623812 RGD:9686118 NCBI chr 2:152,736,251...152,737,410
Ensembl chr 2:152,736,251...152,737,410
JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit ISO RGD PMID:8070348 RGD:12911020 NCBI chr17:24,877,844...24,882,011
Ensembl chr17:24,865,997...24,882,010
JBrowse link
G Inpp5k inositol polyphosphate 5-phosphatase K ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr11:75,629,067...75,648,865
Ensembl chr11:75,630,988...75,648,871
JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 IMP
ISO
(MGI:MGI:5430891|PMID:17563371) BHF-UCL
MGI
PMID:17563371 GO_REF:0000096, MGI:MGI:4834177, MGI:MGI:5430891 NCBI chr 7:80,711,583...80,815,549
Ensembl chr 7:80,711,583...80,825,974
JBrowse link
G Ireb2 iron responsive element binding protein 2 ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr 9:54,862,658...54,912,534
Ensembl chr 9:54,863,789...54,912,530
JBrowse link
G Knstrn kinetochore-localized astrin/SPAG5 binding ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 2:118,813,988...118,837,210
Ensembl chr 2:118,814,003...118,853,957
JBrowse link
G Mars1 methionine-tRNA synthetase 1 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr10:127,296,221...127,311,786
Ensembl chr10:127,296,221...127,311,786
JBrowse link
G Mcm7 minichromosome maintenance complex component 7 ISO RGD PMID:19821535 RGD:2316313 NCBI chr 5:138,164,583...138,172,111
Ensembl chr 5:138,164,583...138,172,422
JBrowse link
G Med1 mediator complex subunit 1 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr11:98,152,154...98,193,313
Ensembl chr11:98,152,154...98,193,293
JBrowse link
G Muc5ac mucin 5, subtypes A and C, tracheobronchial/gastric ISO RGD PMID:11769575 RGD:2324971 NCBI chr 7:141,788,958...141,819,227
Ensembl chr 7:141,788,972...141,819,231
JBrowse link
G Myc myelocytomatosis oncogene ISO RGD PMID:7524476 RGD:10059620 NCBI chr15:61,985,341...61,990,361
Ensembl chr15:61,985,391...61,990,374
JBrowse link
G Ncl nucleolin IDA (MGI:MGI:82360|PMID:8702723) MGI PMID:8702723 MGI:MGI:82360 NCBI chr 1:86,344,719...86,359,455
Ensembl chr 1:86,344,719...86,359,400
JBrowse link
G Pax2 paired box 2 ISO RGD PMID:11262416 RGD:2316756 NCBI chr19:44,746,601...44,838,269
Ensembl chr19:44,756,045...44,837,871
JBrowse link
G Pde8a phosphodiesterase 8A IMP
IBA
ISO
(MGI:MGI:5484722|PMID:23509299)
(MGI:MGI:6201960|PMID:21873635)
UniProtKB
GO_Central
MGI
PMID:21873635, PMID:23509299 GO_REF:0000096, MGI:MGI:4834177, MGI:MGI:5484722, MGI:MGI:6201960 NCBI chr 7:81,213,265...81,334,535
Ensembl chr 7:81,213,596...81,334,533
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase 1 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr17:24,073,680...24,155,619
Ensembl chr17:24,073,680...24,150,924
JBrowse link
G Plcg1 phospholipase C, gamma 1 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 2:160,731,310...160,775,760
Ensembl chr 2:160,731,300...160,775,760
JBrowse link
G Ppp1r9b protein phosphatase 1, regulatory subunit 9B ISO RGD PMID:10620493 RGD:10002737 NCBI chr11:94,991,212...95,006,898
Ensembl chr11:94,991,035...95,006,899
JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 5:121,130,533...121,191,397
Ensembl chr 5:121,130,533...121,191,397
JBrowse link
G Ptpn12 protein tyrosine phosphatase, non-receptor type 12 ISO
IBA
(MGI:MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096, MGI:MGI:4834177, MGI:MGI:6201960 NCBI chr 5:20,986,645...21,055,911
Ensembl chr 5:20,986,645...21,055,911
JBrowse link
G Rasa1 RAS p21 protein activator 1 ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr13:85,214,699...85,289,486
Ensembl chr13:85,214,780...85,289,130
JBrowse link
G Snai2 snail family zinc finger 2 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr16:14,705,852...14,709,395
Ensembl chr16:14,705,852...14,709,385
JBrowse link
G Snx6 sorting nexin 6 ISO MGI GO_REF:0000096, MGI:MGI:4417868 NCBI chr12:54,746,339...54,795,749
Ensembl chr12:54,746,349...54,795,703
JBrowse link
G Sox9 SRY (sex determining region Y)-box 9 IDA (MGI:MGI:5285125|PMID:21512138) UniProtKB PMID:21512138 MGI:MGI:5285125 NCBI chr11:112,782,210...112,787,757
Ensembl chr11:112,782,224...112,787,760
JBrowse link
G Stat5b signal transducer and activator of transcription 5B ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr11:100,780,731...100,859,004
Ensembl chr11:100,780,731...100,850,724
JBrowse link
G Syap1 synapse associated protein 1 IMP
ISO
(MGI:MGI:6114863|PMID:23300339) UniProtKB
MGI
PMID:23300339 GO_REF:0000096, MGI:MGI:4834177, MGI:MGI:6114863 NCBI chr  X:162,856,843...162,888,462
Ensembl chr  X:162,857,057...162,888,447
JBrowse link
G Tdgf1 teratocarcinoma-derived growth factor 1 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 9:110,939,608...110,946,158
Ensembl chr 9:110,939,603...110,946,158
JBrowse link
G Vil1 villin 1 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 1:74,409,384...74,435,560
Ensembl chr 1:74,409,376...74,435,559
JBrowse link
G Zfp36 zinc finger protein 36 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 7:28,376,784...28,379,228
Ensembl chr 7:28,376,784...28,380,253
JBrowse link
G Zfp36l1 zinc finger protein 36, C3H type-like 1 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr12:80,107,760...80,113,013
Ensembl chr12:80,107,754...80,113,013
JBrowse link
G Zfp36l2 zinc finger protein 36, C3H type-like 2 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr17:84,183,924...84,187,947
Ensembl chr17:84,183,931...84,187,947
JBrowse link
G Zpr1 ZPR1 zinc finger ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 9:46,273,064...46,282,643
Ensembl chr 9:46,273,064...46,282,643
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23369
    response to stimulus 10280
      response to endogenous stimulus 2027
        response to epidermal growth factor 67
          cellular response to epidermal growth factor stimulus 57
Path 2
Term Annotations click to browse term
  biological_process 23369
    response to stimulus 10280
      response to chemical 5344
        response to organic substance 3991
          response to growth factor 810
            response to epidermal growth factor 67
              cellular response to epidermal growth factor stimulus 57
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.