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ONTOLOGY REPORT - ANNOTATIONS


Term:response to epidermal growth factor
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Accession:GO:0070849 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.
Synonyms:exact_synonym: response to EGF stimulus;   response to epidermal growth factor stimulus


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response to epidermal growth factor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASCL1 achaete-scute family bHLH transcription factor 1 ISO RGD PMID:9473334 RGD:2314149 NCBI chr 5:81,357,431...81,360,335 JBrowse link
G IGF1 insulin like growth factor 1 ISO RGD PMID:2003595 RGD:12910130 NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,037
JBrowse link
G IL1R1 interleukin 1 receptor type 1 ISO RGD PMID:9233842 RGD:8662880 NCBI chr 3:52,192,912...52,334,734
Ensembl chr 3:52,192,914...52,288,515
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 ISO (PMID:18794356) UniProtKB PMID:18794356 NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,523
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 IEA Ensembl GO_REF:0000107 NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567
JBrowse link
G SERPINE1 serpin family E member 1 ISO RGD PMID:1333984 RGD:8547845 NCBI chr 3:8,863,738...8,871,572
Ensembl chr 3:8,863,695...8,871,564
JBrowse link
G SFTPA1 surfactant protein A1 ISO RGD PMID:19781387 RGD:4143468 NCBI chr14:82,091,178...82,095,393
Ensembl chr14:82,091,178...82,107,675
JBrowse link
G SFTPB surfactant protein B ISO RGD PMID:19781387 RGD:4143468 NCBI chr 3:59,101,940...59,113,442
Ensembl chr 3:59,101,952...59,111,834
JBrowse link
G TPR translocated promoter region, nuclear basket protein IEA Ensembl GO_REF:0000107 NCBI chr 9:127,481,678...127,540,393
Ensembl chr 9:127,481,684...127,540,790
JBrowse link
cellular response to epidermal growth factor stimulus term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTR3 actin related protein 3 ISO RGD PMID:10209028 RGD:2306208 NCBI chr15:20,104,808...20,171,721
Ensembl chr15:20,104,846...20,208,186
JBrowse link
G AKT1 AKT serine/threonine kinase 1 ISO (MGI:MGI:5292318|PMID:21712384) UniProtKB PMID:21712384 MGI:MGI:5292318
G ARPC2 actin related protein 2/3 complex subunit 2 ISO RGD PMID:15252126 RGD:2306210 NCBI chr15:120,297,122...120,328,795
Ensembl chr15:120,297,127...120,329,059
JBrowse link
G BAG4 BAG cochaperone 4 IEA Ensembl GO_REF:0000107 NCBI chr15:48,299,456...48,348,810
Ensembl chr15:48,299,662...48,348,527
JBrowse link
G BAIAP2 BAR/IMD domain containing adaptor protein 2 ISO RGD PMID:17855387 RGD:2306203 NCBI chr12:1,609,420...1,666,965
Ensembl chr12:1,603,538...1,670,076
JBrowse link
G BECN1 beclin 1 ISO RGD PMID:20539009 RGD:6483081 NCBI chr12:20,041,914...20,054,249
Ensembl chr12:20,041,956...20,054,373
JBrowse link
G CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase ISO RGD PMID:10659854 RGD:2303528 NCBI chr 3:111,887,017...111,914,511
Ensembl chr 3:111,887,020...111,914,495
JBrowse link
G CBL Cbl proto-oncogene ISO RGD PMID:22203672 RGD:11576305 NCBI chr 9:46,416,937...46,512,855
Ensembl chr 9:46,404,999...46,512,834
JBrowse link
G CFL1 cofilin 1 ISO RGD PMID:23704350, PMID:26324884 RGD:11568705, RGD:11570555 NCBI chr 2:6,471,558...6,475,019
Ensembl chr 2:6,469,254...6,475,035
JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator ISO RGD PMID:16033771 RGD:11341689 NCBI chr15:104,780,744...104,835,631
Ensembl chr15:104,781,615...104,844,921
JBrowse link
G COL1A1 collagen type I alpha 1 chain ISO RGD PMID:2016852 RGD:2316227 NCBI chr12:26,379,087...26,397,180
Ensembl chr12:26,379,090...26,397,003
JBrowse link
G DAB2 DAB adaptor protein 2 ISO PMID:12473651 UniProt PMID:12473651 RGD:8553624 NCBI chr16:24,590,638...24,776,937
Ensembl chr16:24,514,722...24,776,903
JBrowse link
G DAB2IP DAB2 interacting protein ISO PMID:11812785 BHF-UCL PMID:11812785 RGD:632628 NCBI chr 1:261,732,280...261,859,833
Ensembl chr 1:261,659,660...261,859,830
JBrowse link
G DUSP22 dual specificity phosphatase 22 IEA Ensembl GO_REF:0000107 NCBI chr 7:43,437...96,270
Ensembl chr 7:43,486...96,270
JBrowse link
G DUSP3 dual specificity phosphatase 3 IEA Ensembl GO_REF:0000107 NCBI chr12:19,336,308...19,349,739
Ensembl chr12:19,336,354...19,349,734
JBrowse link
G EEF1A1 eukaryotic translation elongation factor 1 alpha 1 ISO (PMID:9852145) UniProtKB PMID:9852145 NCBI chr 1:92,421,235...92,425,053
Ensembl chr 1:92,421,005...92,488,565
JBrowse link
G EGFR epidermal growth factor receptor ISO PMID:20639532 UniProt PMID:20639532 RGD:8553583 NCBI chr 9:139,302,410...139,474,632
Ensembl chr 9:139,300,022...139,478,882
JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 IEA Ensembl GO_REF:0000107 NCBI chr12:22,591,621...22,621,384
Ensembl chr12:22,590,725...22,621,351
JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 IEA Ensembl GO_REF:0000107 NCBI chr15:113,966,573...115,096,984
Ensembl chr15:113,973,037...114,696,375
JBrowse link
G ERRFI1 ERBB receptor feedback inhibitor 1 ISO RGD PMID:15556944 RGD:9685545 NCBI chr 6:68,667,651...68,682,629
Ensembl chr 6:68,669,153...68,682,624
JBrowse link
G FOXC1 forkhead box C1 IEA Ensembl GO_REF:0000107 NCBI chr 7:837,088...840,593
Ensembl chr 7:837,171...838,805
JBrowse link
G GAREM1 GRB2 associated regulator of MAPK1 subtype 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:116,100,371...116,324,853
Ensembl chr 6:116,100,370...116,325,331
JBrowse link
G GIT1 GIT ArfGAP 1 ISO RGD PMID:18523162 RGD:13513208 NCBI chr12:45,768,172...45,783,652
Ensembl chr12:45,768,174...45,783,747
JBrowse link
G GRK2 G protein-coupled receptor kinase 2 ISO RGD PMID:24018045 RGD:13792711 NCBI chr 2:5,209,435...5,227,543
Ensembl chr 2:5,209,436...5,227,748
JBrowse link
G HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 ISO RGD PMID:3062579 RGD:10041005 NCBI chr 5:19,485,033...19,491,418
Ensembl chr 5:19,485,096...19,491,419
JBrowse link
G ID1 inhibitor of DNA binding 1, HLH protein ISO RGD PMID:7623812 RGD:9686118 NCBI chr17:35,316,518...35,317,742
Ensembl chr17:35,315,964...35,317,744
JBrowse link
G IGFALS insulin like growth factor binding protein acid labile subunit ISO RGD PMID:8070348 RGD:12911020 NCBI chr 3:40,173,595...40,177,789
Ensembl chr 3:40,174,764...40,177,785
JBrowse link
G INPP5K inositol polyphosphate-5-phosphatase K IEA Ensembl GO_REF:0000107 NCBI chr12:47,717,898...47,738,540
Ensembl chr12:47,717,907...47,738,477
JBrowse link
G IQGAP1 IQ motif containing GTPase activating protein 1 IEA Ensembl GO_REF:0000107 NCBI chr 7:53,020,479...53,129,964
Ensembl chr 7:52,958,106...53,129,960
JBrowse link
G IREB2 iron responsive element binding protein 2 ISO RGD PMID:10889193 RGD:12910555 NCBI chr 7:47,481,539...47,529,199
Ensembl chr 7:47,479,629...47,529,227
JBrowse link
G KNSTRN kinetochore localized astrin (SPAG5) binding protein ISO (PMID:26242911) ARUK-UCL PMID:26242911 NCBI chr 1:130,916,956...130,930,172
Ensembl chr 1:130,893,983...130,940,350
JBrowse link
G LOC100739163 glutathione S-transferase P-like ISO RGD PMID:1908848 RGD:2317845 NCBI chr 2:4,978,761...4,982,233 JBrowse link
G MARS1 methionyl-tRNA synthetase 1 IEA Ensembl GO_REF:0000107 NCBI chr 5:22,752,405...22,785,509
Ensembl chr 5:22,751,921...22,785,928
JBrowse link
G MCM7 minichromosome maintenance complex component 7 ISO RGD PMID:19821535 RGD:2316313 NCBI chr 3:8,005,890...8,014,047
Ensembl chr 3:8,005,900...8,014,053
JBrowse link
G MED1 mediator complex subunit 1 ISS UniProt GO_REF:0000024 NCBI chr12:22,830,405...22,872,420
Ensembl chr12:22,839,005...22,872,407
JBrowse link
G MUC5AC mucin 5AC, oligomeric mucus/gel-forming ISO RGD PMID:11769575 RGD:2324971 NCBI chr 2:757,897...790,321 JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO RGD PMID:7524476 RGD:10059620 NCBI chr 4:12,455,141...12,460,360
Ensembl chr 4:12,455,119...12,461,078
JBrowse link
G NCL nucleolin IEA Ensembl GO_REF:0000107 NCBI chr15:132,163,453...132,174,214
Ensembl chr15:132,163,002...132,174,220
JBrowse link
G PAX2 paired box 2 ISO RGD PMID:11262416 RGD:2316756 NCBI chr14:111,822,334...111,914,950
Ensembl chr14:111,834,168...111,914,304
JBrowse link
G PDE8A phosphodiesterase 8A IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:52,410,766...52,558,482
Ensembl chr 7:52,410,779...52,556,884
JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 IEA Ensembl GO_REF:0000107 NCBI chr 3:39,429,928...39,512,623
Ensembl chr 3:39,429,931...39,532,583
JBrowse link
G PLCG1 phospholipase C gamma 1 IEA Ensembl GO_REF:0000107 NCBI chr17:43,810,003...43,844,553
Ensembl chr17:43,809,677...43,844,555
JBrowse link
G PPP1R9B protein phosphatase 1 regulatory subunit 9B ISO RGD PMID:10620493 RGD:10002737 NCBI chr12:26,319,123...26,337,089
Ensembl chr12:26,319,124...26,336,562
JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 IEA Ensembl GO_REF:0000107 NCBI chr14:39,202,165...39,292,041
Ensembl chr14:39,202,168...39,292,018
JBrowse link
G PTPN12 protein tyrosine phosphatase non-receptor type 12 IEA Ensembl GO_REF:0000107 NCBI chr 9:102,480,914...102,563,969
Ensembl chr 9:102,480,922...102,563,905
JBrowse link
G RASA1 RAS p21 protein activator 1 ISO RGD PMID:2005883 RGD:10002731 NCBI chr 2:94,879,615...94,992,725
Ensembl chr 2:94,878,911...94,993,479
JBrowse link
G SNAI2 snail family transcriptional repressor 2 IEA Ensembl GO_REF:0000107 NCBI chr 4:79,264,880...79,268,475
Ensembl chr 4:79,264,878...79,268,475
JBrowse link
G SNX6 sorting nexin 6 ISO RGD PMID:18523162 RGD:13513208 NCBI chr 7:65,156,476...65,205,249
Ensembl chr 7:65,156,472...65,205,241
JBrowse link
G SOX9 SRY-box transcription factor 9 ISS
IEA
UniProt
Ensembl
GO_REF:0000024, GO_REF:0000107 NCBI chr12:8,642,154...8,647,315
Ensembl chr12:8,642,158...8,647,315
JBrowse link
G STAT5B signal transducer and activator of transcription 5B ISS UniProt GO_REF:0000024 NCBI chr12:20,498,103...20,574,365
Ensembl chr12:20,508,403...20,574,288
JBrowse link
G SYAP1 synapse associated protein 1 IEA Ensembl GO_REF:0000107 NCBI chr  X:13,181,948...13,206,948
Ensembl chr  X:13,181,953...13,208,347
JBrowse link
G TDGF1 teratocarcinoma-derived growth factor 1 IEA Ensembl GO_REF:0000107 NCBI chr13:29,537,874...29,544,686
Ensembl chr13:29,540,314...29,543,893
JBrowse link
G VIL1 villin 1 ISS
IEA
UniProt
Ensembl
GO_REF:0000024, GO_REF:0000107 NCBI chr15:120,463,470...120,494,772
Ensembl chr15:120,463,566...120,492,580
JBrowse link
G ZFP36 ZFP36 ring finger protein ISO (PMID:20166898) UniProtKB PMID:20166898 NCBI chr 6:48,063,732...48,066,235
Ensembl chr 6:48,052,137...48,066,257
JBrowse link
G ZFP36L1 ZFP36 ring finger protein like 1 IEA Ensembl GO_REF:0000107 NCBI chr 7:92,490,069...92,495,864
Ensembl chr 7:92,490,011...92,495,574
JBrowse link
G ZFP36L2 ZFP36 ring finger protein like 2 IEA Ensembl GO_REF:0000107 NCBI chr 3:97,200,395...97,203,094
Ensembl chr 3:97,200,406...97,204,700
JBrowse link
G ZPR1 ZPR1 zinc finger IEA Ensembl GO_REF:0000107 NCBI chr 9:44,167,422...44,178,137
Ensembl chr 9:44,166,040...44,180,307
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16524
    response to stimulus 8966
      response to endogenous stimulus 1921
        response to epidermal growth factor 66
          cellular response to epidermal growth factor stimulus 57
Path 2
Term Annotations click to browse term
  biological_process 16524
    response to stimulus 8966
      response to chemical 5474
        response to organic substance 3519
          response to growth factor 783
            response to epidermal growth factor 66
              cellular response to epidermal growth factor stimulus 57
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.