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Term:response to epidermal growth factor
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Accession:GO:0070849 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.
Synonyms:exact_synonym: response to EGF stimulus;   response to epidermal growth factor stimulus

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response to epidermal growth factor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl1 achaete-scute family bHLH transcription factor 1 ISO RGD PMID:9473334 RGD:2314149 NCBI chrNW_004936492:11,315,929...11,317,166 JBrowse link
G Igf1 insulin like growth factor 1 ISO RGD PMID:2003595 RGD:12910130 NCBI chrNW_004936492:11,709,623...11,784,028 JBrowse link
G Il1r1 interleukin 1 receptor type 1 ISO RGD PMID:9233842 RGD:8662880 NCBI chrNW_004936713:808,761...881,070 JBrowse link
G Mapk1 mitogen-activated protein kinase 1 ISO (PMID:18794356) UniProtKB PMID:18794356 NCBI chrNW_004936619:1,889,841...1,932,646 JBrowse link
G Mapk3 mitogen-activated protein kinase 3 ISO (PMID:18794356), (PMID:21968647) UniProtKB PMID:18794356, PMID:21968647 NCBI chrNW_004936501:12,342,670...12,390,650 JBrowse link
G Serpine1 serpin family E member 1 ISO RGD PMID:1333984 RGD:8547845 NCBI chrNW_004936543:1,032,543...1,040,956 JBrowse link
G Sftpb surfactant protein B ISO RGD PMID:19781387 RGD:4143468 NCBI chrNW_004936712:1,614,979...1,621,207 JBrowse link
G Tpr translocated promoter region, nuclear basket protein ISO (PMID:18794356) UniProtKB PMID:18794356 NCBI chrNW_004936481:4,050,693...4,111,682 JBrowse link
cellular response to epidermal growth factor stimulus term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actr3 actin related protein 3 ISO RGD PMID:10209028 RGD:2306208 NCBI chrNW_004936469:55,639,345...55,699,330 JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO (MGI:MGI:5292318|PMID:21712384) UniProtKB PMID:21712384 MGI:MGI:5292318 NCBI chrNW_004936621:620,163...639,115 JBrowse link
G Arpc2 actin related protein 2/3 complex subunit 2 ISO RGD PMID:15252126 RGD:2306210 NCBI chrNW_004936569:758,358...786,995 JBrowse link
G Bag4 BAG cochaperone 4 ISO (MGI:MGI:5292318|PMID:21712384) UniProtKB PMID:21712384 MGI:MGI:5292318 NCBI chrNW_004936710:1,551,729...1,575,393 JBrowse link
G Baiap2 BAR/IMD domain containing adaptor protein 2 ISO RGD PMID:17855387 RGD:2306203 NCBI chrNW_004936594:4,797,068...4,863,409 JBrowse link
G Becn1 beclin 1 ISO RGD PMID:20539009 RGD:6483081 NCBI chrNW_004936490:17,518,100...17,531,126 JBrowse link
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase ISO RGD PMID:10659854 RGD:2303528 NCBI chrNW_004936493:5,308,268...5,332,934 JBrowse link
G Cbl Cbl proto-oncogene ISO RGD PMID:22203672 RGD:11576305 NCBI chrNW_004936542:4,136,389...4,235,746 JBrowse link
G Cfl1 cofilin 1 ISO RGD PMID:23704350, PMID:26324884 RGD:11568705, RGD:11570555 NCBI chrNW_004936599:3,678,724...3,682,314 JBrowse link
G Cflar CASP8 and FADD like apoptosis regulator ISO RGD PMID:16033771 RGD:11341689 NCBI chrNW_004936726:381,888...425,565 JBrowse link
G Col1a1 collagen type I alpha 1 chain ISO RGD PMID:2016852 RGD:2316227 NCBI chrNW_004936490:11,448,552...11,465,836 JBrowse link
G Dab2 DAB adaptor protein 2 ISO PMID:12473651 UniProt PMID:12473651 RGD:8553624 NCBI chrNW_004936518:2,915,819...2,936,474 JBrowse link
G Dab2ip DAB2 interacting protein ISO PMID:11812785 BHF-UCL PMID:11812785 RGD:632628 NCBI chrNW_004936487:10,056,809...10,243,021 JBrowse link
G Dusp22 dual specificity phosphatase 22 ISO (PMID:20018849) ARUK-UCL PMID:20018849 NCBI chrNW_004936633:1,459,487...1,528,080 JBrowse link
G Dusp3 dual specificity phosphatase 3 ISO (MGI:MGI:6101044|PMID:28759036)
BHF-UCL PMID:28759036 MGI:MGI:6101044 NCBI chrNW_004936541:325,443...338,426 JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 ISO (PMID:9852145) UniProtKB PMID:9852145 NCBI chrNW_004936859:740,620...744,534 JBrowse link
G Egfr epidermal growth factor receptor ISO PMID:20639532 UniProt PMID:20639532 RGD:8553583 NCBI chrNW_004936678:365,005...560,546 JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO (PMID:27134172) UniProtKB PMID:27134172 NCBI chrNW_004936490:14,887,062...14,910,038 JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 ISO (MGI:MGI:82360|PMID:8702723) MGI PMID:8702723 MGI:MGI:82360 NCBI chrNW_004936586:4,065,767...5,100,690 JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 ISO RGD PMID:15556944 RGD:9685545 NCBI chrNW_004936623:2,457,709...2,462,956 JBrowse link
G Garem1 GRB2 associated regulator of MAPK1 subtype 1 ISO (PMID:19509291) UniProtKB PMID:19509291 NCBI chrNW_004936682:947,420...1,068,468 JBrowse link
G Git1 GIT ArfGAP 1 ISO RGD PMID:18523162 RGD:13513208 NCBI chrNW_004936538:5,684,660...5,694,779 JBrowse link
G Grk2 G protein-coupled receptor kinase 2 ISO RGD PMID:24018045 RGD:13792711 NCBI chrNW_004936599:2,437,061...2,456,141 JBrowse link
G Gstp1 glutathione S-transferase pi 1 ISO RGD PMID:1908848 RGD:2317845 NCBI chrNW_004936599:2,197,681...2,200,642 JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 ISO RGD PMID:3062579 RGD:10041005 NCBI chrNW_004936512:11,481,017...11,487,737 JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein ISO RGD PMID:7623812 RGD:9686118 NCBI chrNW_004936485:18,610,721...18,611,889 JBrowse link
G Igfals insulin like growth factor binding protein acid labile subunit ISO RGD PMID:8070348 RGD:12911020 NCBI chrNW_004936694:2,205,294...2,207,343 JBrowse link
G Inpp5k inositol polyphosphate-5-phosphatase K ISO (PMID:21712384) UniProtKB PMID:21712384 NCBI chrNW_004936538:7,641,485...7,662,033 JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 ISO (MGI:MGI:5430891|PMID:17563371)
(PMID:17563371), (PMID:26242911)
PMID:17563371, PMID:26242911 MGI:MGI:5430891 NCBI chrNW_004936483:16,489,127...16,594,712 JBrowse link
G Ireb2 iron responsive element binding protein 2 ISO RGD PMID:10889193 RGD:12910555 NCBI chrNW_004936471:36,547,552...36,601,327 JBrowse link
G Knstrn kinetochore localized astrin (SPAG5) binding protein ISO (PMID:26242911) ARUK-UCL PMID:26242911 NCBI chrNW_004936471:3,838,507...3,849,521 JBrowse link
G Mars1 methionyl-tRNA synthetase 1 ISO (PMID:10791971) CAFA PMID:10791971 NCBI chrNW_004936646:1,644,457...1,665,081 JBrowse link
G Mcm7 minichromosome maintenance complex component 7 ISO RGD PMID:19821535 RGD:2316313 NCBI chrNW_004936543:238,573...246,746 JBrowse link
G Med1 mediator complex subunit 1 ISO (PMID:16314496) UniProtKB PMID:16314496 NCBI chrNW_004936490:14,625,201...14,663,184 JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming ISO RGD PMID:11769575 RGD:2324971 NCBI chrNW_004936816:129,926...159,396 JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor ISO RGD PMID:7524476 RGD:10059620 NCBI chrNW_004936470:20,480,844...20,485,955 JBrowse link
G Pax2 paired box 2 ISO RGD PMID:11262416 RGD:2316756 NCBI chrNW_004936600:4,850,594...4,939,010 JBrowse link
G Pde8a phosphodiesterase 8A ISO (MGI:MGI:5484722|PMID:23509299)
UniProtKB PMID:23509299 MGI:MGI:5484722 NCBI chrNW_004936483:17,009,696...17,163,105 JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase 1 ISO (PMID:22454520) BHF-UCL PMID:22454520 NCBI chrNW_004936694:1,444,819...1,487,628 JBrowse link
G Plcg1 phospholipase C gamma 1 ISO (PMID:17229814)
PMID:17229814, PMID:22454520 NCBI chrNW_004936561:598,372...631,575 JBrowse link
G Ppp1r9b protein phosphatase 1 regulatory subunit 9B ISO RGD PMID:10620493 RGD:10002737 NCBI chrNW_004936490:11,497,389...11,514,191 JBrowse link
G Ptpn11 protein tyrosine phosphatase non-receptor type 11 ISO (PMID:28074573) UniProtKB PMID:28074573 NCBI chrNW_004936668:2,602,261...2,687,903 JBrowse link
G Ptpn12 protein tyrosine phosphatase non-receptor type 12 ISO (PMID:27134172) UniProtKB PMID:27134172 NCBI chrNW_004936479:20,909,557...21,016,562 JBrowse link
G Rasa1 RAS p21 protein activator 1 ISO RGD PMID:2005883 RGD:10002731 NCBI chrNW_004936469:5,839,560...5,933,049 JBrowse link
G Snai2 snail family transcriptional repressor 2 ISO (PMID:18716062) BHF-UCL PMID:18716062 NCBI chrNW_004936590:3,813,916...3,817,642 JBrowse link
G Snx6 sorting nexin 6 ISO RGD PMID:18523162 RGD:13513208 NCBI chrNW_004936494:8,819,695...8,880,298 JBrowse link
G Sox9 SRY-box transcription factor 9 ISO (MGI:MGI:5285125|PMID:21512138) UniProtKB PMID:21512138 MGI:MGI:5285125 NCBI chrNW_004936655:1,849,044...1,852,648 JBrowse link
G Stat5b signal transducer and activator of transcription 5B ISO PMID:20639532 UniProt PMID:20639532 RGD:8553583 NCBI chrNW_004936490:17,022,268...17,043,751 JBrowse link
G Syap1 synapse associated protein 1 ISO (PMID:23300339)
UniProtKB PMID:23300339 MGI:MGI:6114863 NCBI chrNW_004936470:5,994,217...6,026,057 JBrowse link
G Tdgf1 teratocarcinoma-derived growth factor 1 ISO (PMID:17720976) UniProtKB PMID:17720976 NCBI chrNW_004936596:451,483...453,892 JBrowse link
G Vil1 villin 1 ISO (PMID:17229814) UniProtKB PMID:17229814 NCBI chrNW_004936569:914,511...938,481 JBrowse link
G Zfp36 ZFP36 ring finger protein ISO (PMID:20166898) UniProtKB PMID:20166898 NCBI chrNW_004936661:2,251,148...2,253,527 JBrowse link
G Zfp36l1 ZFP36 ring finger protein like 1 ISO (PMID:20166898) UniProtKB PMID:20166898 NCBI chrNW_004936495:12,045,679...12,050,737 JBrowse link
G Zfp36l2 ZFP36 ring finger protein like 2 ISO (PMID:20166898) UniProtKB PMID:20166898 NCBI chrNW_004936508:8,617,185...8,620,823 JBrowse link
G Zpr1 ZPR1 zinc finger ISO (PMID:9852145) UniProtKB PMID:9852145 NCBI chrNW_004936542:2,058,048...2,067,468 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11962
    response to stimulus 6404
      response to endogenous stimulus 1690
        response to epidermal growth factor 63
          cellular response to epidermal growth factor stimulus 55
Path 2
Term Annotations click to browse term
  biological_process 11962
    response to stimulus 6404
      response to chemical 3741
        response to organic substance 3010
          response to growth factor 718
            response to epidermal growth factor 63
              cellular response to epidermal growth factor stimulus 55
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.